Efficient synthesis of (S)-1-(5-fluoropyrimidin-2-yl)ethylamine using an ω-transaminase biocatalyst in a two-phase system

Organic Process Research and Development

Volumn 17, Issue 9, 2013, Pages 1117-1122

  Meadows, Rebecca E ^a,b   Mulholland, Keith R ^b   Schürmann, Martin ^a   Golden, Michael ^b   Kierkels, Hans ^a   Meulenbroeks, Elise ^a   Mink, Daniel ^a   May, Oliver ^a   Squire, Christopher ^b   Straatman, Harrie ^a   Wells, Andrew S ^b  

^a DSM RESOLVE   (Netherlands)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DRY WEIGHT; COMMERCIAL ENZYMES; EFFICIENT SYNTHESIS; LOW COST ENZYMES; METHYLBENZYLAMINE; TWO PHASE SYSTEMS; VIBRIO FLUVIALIS; WHOLE CELL BIOCATALYSTS;

ESCHERICHIA COLI; OPTIMIZATION;

ENZYMES;

EID: 84884634180     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op400131h     Document Type: Article

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