Use of ω-transaminase enzyme chemistry in the synthesis of a JAK2 kinase inhibitor

Organic Process Research and Development

Volumn 17, Issue 9, 2013, Pages 1123-1130

  Frodsham, Lianne ^a   Golden, Michael ^a   Hard, Susan ^a   Kenworthy, Martin N ^a   Klauber, David J ^a   Leslie, Kevin ^a   Macleod, Claire ^a   Meadows, Rebecca E ^a   Mulholland, Keith R ^a   Reilly, Julie ^a   Squire, Christopher ^a   Tomasi, Simone ^a   Watt, Denise ^a   Wells, Andrew S ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHIRAL AMINES; ENZYME CHEMISTRY; KINASE INHIBITORS;

ENZYME INHIBITION; KETONES;

STEREOCHEMISTRY;

EID: 84884666388     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op400133d     Document Type: Article

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