Effects of hydrophilic statins on renal tubular lipid accumulation in diet-induced obese mice

Obesity Research and Clinical Practice

Volumn 7, Issue 5, 2013, Pages

  Gotoh, Koro ^a   Masaki, Takayuki ^a   Chiba, Seiichi ^a   Ando, Hisae ^a   Fujiwara, Kansuke ^a   Shimasaki, Takanobu ^a   Tawara, Yasuko ^a   Toyooka, Ikuko ^a   Shiraishi, Kentaro ^a   Mitsutomi, Kimihiko ^a   Anai, Manabu ^a   Itateyama, Emi ^a   Hiraoka, Junji ^a   Aoki, Kohei ^a   Fukunaga, Naoya ^a   Nawata, Tomoko ^a   Kakuma, Tetsuya ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

Chronic kidney disease; Lipid accumulation; Obesity; Proximal tubules; Statins

Indexed keywords

ADIPONECTIN; ATORVASTATIN; CYSTATIN C; DESMIN; GLUCOSE; INSULIN; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; NEPHRIN; PITAVASTATIN; PRAVASTATIN; ROSUVASTATIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; ENERGY METABOLISM; GLOMERULOPATHY; GLOMERULUS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HYDROPHILICITY; INSULIN BLOOD LEVEL; KIDNEY HYPERTROPHY; KIDNEY INTERSTITIUM; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE; LIPID DIET; LIPID STORAGE; LIPOPHILICITY; MACROPHAGE; MALE; MESANGIUM CELL; METABOLIC PARAMETERS; METABOLIC SYNDROME X; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALIA; MUS;

ADIPONECTIN; ANIMALS; BODY WEIGHT; CHOLESTEROL; CYTOKINES; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KIDNEY DISEASES; KIDNEY TUBULES; LIPID METABOLISM; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; PRAVASTATIN; PYRROLES; QUINOLINES; TRIGLYCERIDES;

EID: 84884596987     PISSN: 1871403X     EISSN: 18780318     Source Type: Journal    
DOI: 10.1016/j.orcp.2013.04.001     Document Type: Article

References (34)

1. S. Watanabe, R. Yamanuma, and A. Ikejima Miyazaki Liver diseases and metabolic syndrome J Gastroenterol 43 2008 509 518
2. S. Kume, T. Uzu, S. Araki, T. Sugimoto, K. Isshiki, and M. Chin-Kanasaki Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet Am J Soc Nephrol 18 2007 2715 2723
3. P. Korantzopoulos, M. Elisaf, and H.J. Milionis Multifactorial intervention in metabolic syndrome targeting at prevention of chronic kidney disease ready for prime time? Nephrol Dail Transplant 22 2007 2768 2774
4. J.F. Moorhead, M.K. Chan, M. El-Nahas, and Z. Varghese Lipid nephrotoxity in chronic progressive glomerular and tubulo-interstitial disease Lancet 2 1982 1309 1311
5. A. Cases, and C. Elisabeth Dyslipidemia and the progression of renal disease in chronic renal failure Kidney Int 68 2005 87 93
6. I.M. Wahba, and R.H. Mak Obesity and obesity-initiated metabolic syndrome: mechanistic links to chronic kidney disease Clin J Am Soc Nephrol 2 2007 550 562
7. B. Afzali, A.A. Haydar, K. Vinen, and D.J. Goldsmith Beneficial effects of statins on the kidney: the evidence moves from mouse to man Nephrol Dial Transplant 19 2004 1032 1036
8. S. Sandhu, N. Wiebe, L.F. Fried, and M. Tonelli Statins for improving renal outcomes: a meta-analysis J Am Soc Nephrol 17 2006 2006 2016
9. G.F. Strippoli, S.D. Navanneethan, D.W. Johnson, V. Perkovic, F. Pellegrini, and A. Nicolucci Effects of statins in patients with chronic kidney disease: meta-analysis and meta-regression of randomized controlled traials BMJ 336 2008 645 651
10. B. Afzali, and D.J. Goldsmith Beneficial effects of statins on the kidney J Clin Pathol 57 2004 673 674
11. M. Epstein, and V.M. Campese Pleiotropic effects of 3-hydroxy3- methylglutaryl coenzyme a reductase inhibitors on renal function Am J Kidney Dis 45 2005 2 14
12. A. Miyazaki, T. Koieyama, Y. Shimada, T. Kikuchi, K. Ito, and N. Kasanuki Pravastatin sodium, an inhibitor of HMG-CoA reductase, decreases HDL cholesterol by transfer of cholesteryl ester from HDL to VLDL in Japanese white rabbits J Atheroscler Thromb 11 1 2004 22 28
13. T. Aoki, H. Yamazaki, H. Suzuki, T. Tamaki, F. Sato, and M. Kitahara Cholesterol-lowering effect of NK-104, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, in guinea pig model of hyperlipidemia Arzneimittelforschung 51 2001 197 203
14. M.F. Mahmoud, M. El-Nagar, and H.M. El-Bassossy Anti-inflammatory effect of atorvastatin on vascular reactivity and insulin resistance in fructose fed rats Arch Pharm Res 35 2012 155 162
15. B. Zhou, Y. Pan, Z. Hu, X. Wang, J. Han, and Q. Zhou All-trans-retinoic acid ameliorated high fat diet-induced atherosclerosis in rabbits by inhibiting platelet activation and inflammation J Biomed Biotechnol 2012 doi: 10.1155
16. K. Stemmer, D. Perez-Tilve, G. Ananthakrishnan, A. Bort, R.J. Seeley, and M.H. Tschöp High-fat-diet-induced obesity causes an inflammatory and tumor-promoting microenvironment in the rat kidney Dis Model Mech 5 2012 627 635
17. X.Z. Ruan, Z. Varghese, and J.F. Moorhead An update on lipid nephrotoxicity hypothesis Nat Rev Nephrol 5 2009 713 721
18. L. Sun, N. Halaihel, W. Zhang, T. Rogers, and M. Levi Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus J Biol Chem 277 2002 18919 18927
19. M.W. Spencer, A.S. Mühlfield, and S. Segerer Hyperglycemia and hyperlipidemia act synergistically to induce renal disease in LDL receptor-deficient BALB mice Am J Nephrol 24 2004 20 31
20. G. Proctor, T. Jiang, M. Iwahashi, Z. Wang, J. Li, and M. Levi Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes Diabetes 55 2006 2502 2509
21. T. Jiang, Z. Wang, G. Proctor, S. Moskowitz, S.E. Liebman, and T. Rogers Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway J Biol Chem 280 2005 32317 32325
22. S. Gordon, and P.R. Tayler Monocyte and macrophage heterogeneity Nat Rev Immunol 5 2005 953 964
23. S. Doublier, G. Salvidio, E. Lupia, V. Ruotsalainen, D. Verzola, and G. Deferrari Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin 2 Diabetes 52 2003 1023 1030
24. T. Ota, M. Tamura, A. Osajima, Y. Doi, H. Kudo, and H. Anai Expression of monocyte chemoattractant protein-1 in proximal tubular epithelial cells in a rat model of progressive kidney failure J Lab Med 140 2002 43 51
25. J.K. Sethi, and A.J. Vidal-Puig Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation J Lipid Res 48 2007 1253 1262
26. P.J. Ebenezer, N. Mariappan, C.M. Elks, M. Haque, Z. Soltani, and E. Reisin Effects of pyrrolidine dithiocarbamate on high-fat diet-induced metabolic and renal alterations in rats Life Sci 85 2009 357 364
27. M. von Eynatten, J.G. Schneider, S. Hadziselimovic, A. Hamann, A. Bierhaus, and P.P. Nawroth Adipocytokines as a novel target for the anti-inflammatory effect of atorvastatin in patients with type 2 diabetes Diabetes Care 28 2005 754 755
28. Y. Takahashi, M. Satoh, T. Tabuchi, and M. Nakamura Protective, randomized, single-blind comparison of effects of 6 months' treatment with atorvastatin versus pravastatin on leptin and angiogenic factors in patients with coronary artery disease Heart Vessels 27 2012 337 343
29. P. Anagnostis, D. Selalmatzidou, S.A. Polyzos, A. Panagiotou, A. Slavakis, and A. Panagiotidou Comparative effects of rosuvastatin and atorvastatin on glucose metabolism and adipokine levels in non-diabetic patients with dyslipidemia: a prospective randomized open-label study Int J Clin Pract 65 2011 679 683
30. N. Thongtang, M. Ai, S. Otokozawa, T.V. Himbergen, B.F. Asztalos, and K. Nakajima Effects of maximal atorvastatin and rosuvastatin treatment on markers of glucose homeostasis and inflammation Am J Cardiol 107 2011 387 392
31. M. Gupta, P.E. Szmitko, M. Tsigoulis, M.F. Braga, M. Kajil, and S. Herjikaka Effects of ezetimibe add-on to statin therapy on adipokine production in patients with metabolic syndrome and stable vascular disease J Cardiovasc Pharmacol 56 2010 241 245
32. B.M. Cheung, I.J. Lauder, C.R. Lau, and C.R. Kumana Meta-analysis of large randomized controlled trials to evaluate the impact of statins on cardiovascular outcomes Br J ClinPharmacol 57 2004 640 651
33. E. Reisin, J. Liao, P. Ebenezer, B.S. Lee, M. Larroque, and X. Hu Effect of the HMG-CoA reductase inhibitor rosuvastatin on early chronic kidney injury in obese Zucker rats fed with an atherogenic diet Am J Med Sci 338 2009 301 309
34. P.H. Chong, J.D. Seeger, and C. Franklin Clinically relevant differences between the statins: implications for therapeutic selection Am J Med 111 2001 390 400