Huntington disease in the South African population occurs on diverse and ethnically distinct genetic haplotypes

European Journal of Human Genetics

Volumn 21, Issue 10, 2013, Pages 1120-1127

  Baine, Fiona K ^a,b   Kay, Chris ^b   Ketelaar, Maria E ^b,c   Collins, Jennifer A ^b   Semaka, Alicia ^b   Doty, Crystal N ^b   Krause, Amanda ^d   Jacquie Greenberg, L ^a   Hayden, Michael R ^a,b  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

CAG expansion; haplogroups; haplotypes; Huntington disease; prevalence; South Africa

Indexed keywords

HUNTINGTIN;

ALLELE; ARTICLE; CAG REPEAT; CAUCASIAN; ETHNIC DIFFERENCE; EUROPE; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HIGH RISK POPULATION; HUMAN; HUNTINGTON CHOREA; MAJOR CLINICAL STUDY; PREVALENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH AFRICA;

AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; HAPLOTYPES; HUMANS; HUNTINGTON DISEASE; NERVE TISSUE PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; SOUTH AFRICA;

EID: 84884596055     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2013.2     Document Type: Article

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