The effect of subsyndromal symptoms of depression and white matter lesions on disability for individuals with mild cognitive impairment

American Journal of Geriatric Psychiatry

Volumn 21, Issue 9, 2013, Pages 906-914

  Mackin, R Scott ^a,b   Insel, Philip ^a   Tosun, Duygu ^a,c   Mueller, Susanne G ^a,c   Schuff, Norbert ^a,c   Truran Sacrey, Diana ^a   Raptentsetsang, Sky T ^a   Lee, Jun Young ^a   Jack Jr , Clifford R ^d   Aisen, Paul S ^e   Petersen, Ronald C ^f   Weiner, Michael W ^a,b,c  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MAYO CLINIC   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Mayo Clinic   (United States)

Author keywords

ApoE; Dementia; Disability; Longitudinal; Mild cognitive impairment; Subsyndromal depression; Subthreshold depression; White matter lesions

Indexed keywords

AGED; ALLELE; ALZHEIMER DISEASE ASSESSMENT SCALE; APOLIPOPROTEIN E EPSILON4 GENE; ARTICLE; BRAIN SIZE; COGNITION; DEMENTIA; DEPRESSION; DISABILITY; FEMALE; FUNCTIONAL ASSESSMENT QUESTIONNAIRE; GENE; GERIATRIC DEPRESSION SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MILD COGNITIVE IMPAIRMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; QUESTIONNAIRE; SUBSYNDROMAL SYMPTOMS OF DEPRESSION; WHITE MATTER LESION;

APOE; DEMENTIA; DISABILITY; LONGITUDINAL; MILD COGNITIVE IMPAIRMENT; SUBSYNDROMAL DEPRESSION; SUBTHRESHOLD DEPRESSION; WHITE MATTER LESIONS;

AGED; AGED, 80 AND OVER; APOLIPOPROTEIN E4; BRAIN; DEPRESSION; DISABILITY EVALUATION; FEMALE; GENE FREQUENCY; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MILD COGNITIVE IMPAIRMENT; NERVE FIBERS, MYELINATED; ORGAN SIZE; SEVERITY OF ILLNESS INDEX;

EID: 84884587956     PISSN: 10647481     EISSN: 15457214     Source Type: Journal    
DOI: 10.1016/j.jagp.2013.01.021     Document Type: Article

References (41)

1. Chisholm D, Sanderson K, Ayuso-Mateos JL, et al: Reducing the global burden of depression: population-level analysis of intervention cost-effectiveness in 14 world regions. Br J Psychiatry 2004; 184: 393-403
2. Anstey KJ, von Sanden C, Sargent-Cox K, et al: Prevalence and risk factors for depression in a longitudinal, population-based study including individuals in the community and residential care. Am J Geriatr Psychiatry 2007; 15: 497-505
3. Penninx BW, Beekman AT, Deeg DJ, et al: Effects of depression on physical health and mortality in the elderly. Longitudinal results of the LASA research. Tijdschr Gerontol Geriatr 2000; 31: 211-218
4. Lyketsos CG, Lopez O, Jones B, et al: Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA 2002; 288: 1475-1483
5. Kales HC, Chen P, Blow FC, et al: Rates of clinical depression diagnosis, functional impairment, and nursing home placement in coexisting dementia and depression. Am J Geriatr Psychiatry 2005; 13: 441-449
6. Kiosses DN, Klimstra S, Murphy C, et al: Executive dysfunction and disability in elderly patients with major depression. Am J Geriatr Psychiatry 2001; 9: 269-274
7. Dorenlot P, Harboun M, Bige V, et al: Major depression as a risk factor for early institutionalization of dementia patients living in the community. Int J Geriatr Psychiatry 2005; 20: 471-478
8. Lyness JM, Chapman BP, McGriff J, et al: One-year outcomes of minor and subsyndromal depression in older primary care patients. Int Psychogeriatr 2009; 21: 60-68
9. Goldney RD, Fisher LJ, Dal Grande E, et al: Subsyndromal depression: prevalence, use of health services and quality of life in an Australian population. Soc Psychiatry Psychiatr Epidemiol 2004; 39: 293-298
10. Geda YE, Roberts RO, Knopman DS, et al: Prevalence of neuropsychiatric symptoms in mild cognitive impairment and normal cognitive aging: population-based study. Arch Gen Psychiatry 2008; 65: 1193-1198
11. Gabryelewicz T, Styczynska M, Pfeffer A, et al: Prevalence of major and minor depression in elderly persons with mild cognitive impairment: MADRS factor analysis. Int J Geriatr Psychiatry 2004; 19: 1168-1172
12. Chopra MP, Zubritsky C, Knott K, et al: Importance of subsyndromal symptoms of depression in elderly patients. Am J Geriatr Psychiatry 2005; 13: 597-606
13. Lyness JM, Kim J, Tang W, et al: The clinical significance of subsyndromal depression in older primary care patients. Am J Geriatr Psychiatry 2007; 15: 214-223
14. Muangpaisan W, Assantachai P, Intalapaporn S, et al: Quality of life of the community-based patients with mild cognitive impairment. Geriatr Gerontol Int 2008; 8: 80-85
15. Panza F, Capurso C, D'Introno A, et al: Impact of depressive symptoms on the rate of progression to dementia in patients affected by mild cognitive impairment. The Italian longitudinal study on aging. Int J Geriatr Psychiatry 2008; 23: 726-734
16. Gabryelewicz T, Styczynska M, Luczywek E, et al: The rate of conversion of mild cognitive impairment to dementia: predictive role of depression. Int J Geriatr Psychiatry 2007; 22: 563-567
17. Hannestad J, Taylor WD, McQuoid DR, et al: White matter lesion volumes and caudate volumes in late-life depression. Int J Geriatr Psychiatry 2006; 21: 1193-1198
18. Kuo HK, Lipsitz LA: Cerebral white matter changes and geriatric syndromes: is there a link? J Gerontol A Biol Sci Med Sci 2004; 59: 818-826
19. Sachdev PS, Wen W, Christensen H, et al: White matter hyperintensities are related to physical disability and poor motor function. J Neurol Neurosurg Psychiatry 2005; 76: 362-367
20. Steffens DC, Norton MC, Hart AD, et al: Apolipoprotein E genotype and major depression in a community of older adults. The Cache County Study. Psychol Med 2003; 33: 541-547
21. Folstein MF, Robins LN, Helzer JE: The mini-mental state examination. Arch Gen Psychiatry 1983; 40:812
22. Morris JC: The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 1993; 43: 2412-2414
23. Yesavage JA, Brink TL, Rose TL, et al: Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982; 17: 37-49
24. McKhann G, Drachman D, Folstein M, et al: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984; 34: 939-944
25. Pfeffer RI, Kurosaki TT, Harrah CH Jr, et al: Measurement of functional activities in older adults in the community. J Gerontol 1982; 37: 323-329
26. Marc LG, Raue PJ, Bruce ML: Screening performance of the 15- item geriatric depression scale in a diverse elderly home care population. Am J Geriatr Psychiatry 2008; 16: 914-921
27. Rosen WG, Mohs RC, Davis KL: A new rating scale for Alzheimer's disease. Am J Psychiatry 1984; 141: 1356-1364
28. Jack CR Jr., Bernstein MA, Fox NC, et al: The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods. J Magn Reson Imaging 2008; 27: 685-691
29. Leow AD, Klunder AD, Jack CR Jr, et al: Longitudinal stability of MRI for mapping brain change using tensor-based morphometry. Neuroimage 2006; 31: 627-640
30. Jack CR Jr., Petersen RC, Grundman M, et al: Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI. Neurobiol Aging 2008; 29: 1285-1295
31. Smith EE, Salat DH, Jeng J, et al: Correlations between MRI white matter lesion location and executive function and episodic memory. Neurology 2011; 76: 1492-1499
32. Fischl B, van der Kouwe A, Destrieux C, et al: Automatically parcellating the human cerebral cortex. Cereb Cortex 2004; 14: 11-22
33. Tadic A, Helmreich I, Mergl R, et al: Early improvement is a predictor of treatment outcome in patients with mild major, minor or subsyndromal depression. J Affect Disord 2010; 120(1): 86-93
34. Oxman TE, Hegel MT, Hull JG, et al: Problem-solving treatment and coping styles in primary care for minor depression. J Consult Clin Psychol 2008; 76: 933-943
35. Brenes GA, Williamson JD, Messier SP, et al: Treatment of minor depression in older adults: a pilot study comparing sertraline and exercise. Aging Ment Health 2007; 11: 61-68
36. Rosenberg D, Depp CA, Vahia IV, et al: Exergames for subsyndromal depression in older adults: a pilot study of a novel intervention. Am J Geriatr Psychiatry 2010; 18: 221-226
37. Arean PA, Raue P, Mackin RS, et al: Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction. Am J Psychiatry 2010; 167: 1391-1398
38. Alexopoulos GS, Meyers BS, Young RC, et al: "Vascular depression" hypothesis. Arch Gen Psychiatry 1997; 54: 915-922
39. Penninx BW, Leveille S, Ferrucci L, et al: Exploring the effect of depression on physical disability: longitudinal evidence from the established populations for epidemiologic studies of the elderly. Am J Public Health 1999; 89: 1346-1352
40. Debruyne H, Van Buggenhout M, Le Bastard N, et al: Is the geriatric depression scale a reliable screening tool for depressive symptoms in elderly patients with cognitive impairment? Int J Geriatr Psychiatry 2009; 24: 556-562
41. Almeida JR, Alves TC,Wajngarten M, et al: Late-life depression, heart failure and frontalwhitematter hyperintensity: a structuralmagnetic resonance imaging study. Braz J Med Biol Res 2005; 38: 431-436