Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events

Journal of the American College of Cardiology

Volumn 62, Issue 14, 2013, Pages 1267-1276

  Voora, Deepak ^a,b   Cyr, Derek ^a   Lucas, Joseph ^a   Chi, Jen Tsan ^a   Dungan, Jennifer ^b   Mccaffrey, Timothy A ^c   Katz, Richard ^d   Newby, L Kristin ^b   Kraus, William E ^b   Becker, Richard C ^b   Ortel, Thomas L ^b   Ginsburg, Geoffrey S ^a,b  

^a DUKE UNIVERSITY   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GEORGE WASHINGTON UNIVERSITY   (United States)

^d GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

aspirin; biomarkers; genes; myocardial infarction; platelets

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA2 INTEGRIN; ALPHA2B INTEGRIN; BETA 1 TUBULIN; BETA TUBULIN; BETA3 INTEGRIN; BIOLOGICAL MARKER; CALDESMON; CALDESMON 1; CHEMOKINE RECEPTOR; CLUSTERIN; CXCL7 CHEMOKINE; GLYCOPROTEIN IB; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN 9; NUCLEAR PROTEIN; OSTEONECTIN; PHOSPHATIDYLSERINE; PHOSPHODIESTERASE V; PHOSPHODIESTERASE VA; PROTEIN SH3; PROTEOME; RAB PROTEIN; RAB27B PROTEIN; RNA; SDPR PROTEIN; STEROID RECEPTOR COACTIVATOR 8; THROMBOCYTE FACTOR 4; THROMBOSPONDIN 1; UNCLASSIFIED DRUG;

ARS GENE; ARTICLE; BAYES THEOREM; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; DEATH; DISEASE CLASSIFICATION; DRUG EXPOSURE; DRUG RESPONSE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HEART CATHETERIZATION; HEART INFARCTION; HUMAN; ITGA2B GENE; PRIORITY JOURNAL; PROTEIN ANALYSIS; THROMBOCYTE FUNCTION;

ARS; ASPIRIN; ASPIRIN RESPONSE SIGNATURE; BIOMARKERS; CAD; CATHETERIZATION GENETICS; CATHGEN; CI; CONFIDENCE INTERVAL; CORONARY ARTERY DISEASE; DUKE UNIVERSITY MEDICAL CENTER; DUMC; GENES; HEALTHY VOLUNTEER DISCOVERY COHORT; HEALTHY VOLUNTEER VALIDATION COHORT; HV1; HV2; MEAN PLATELET VOLUME; MI; MPV; MYOCARDIAL INFARCTION; ODDS RATIO; OPC; OR; OUTPATIENT CARDIOLOGY COHORT; PCR; PFS; PLATELET FUNCTION SCORE; PLATELETS; POLYMERASE CHAIN REACTION; REAL-TIME POLYMERASE CHAIN REACTION; RIBONUCLEIC ACID; RNA; RT-PCR;

ASPIRIN; BAYES THEOREM; BLOOD PLATELETS; CARDIOVASCULAR DISEASES; GENES; HUMANS; MICROARRAY ANALYSIS; PLATELET AGGREGATION INHIBITORS; PLATELET FUNCTION TESTS; PROTEOMICS; REAL-TIME POLYMERASE CHAIN REACTION; RISK FACTORS; RNA;

EID: 84884564336     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.05.073     Document Type: Article

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