Preparation and characterization of minoxidil loaded nanostructured lipid carrier gel for effective treatment of alopecia

Saudi Pharmaceutical Journal

Volumn 21, Issue 4, 2013, Pages 379-385

  Uprit, Shubham ^a   Kumar Sahu, Ram ^b   Roy, Amit ^b   Pare, Aniruddha ^c  

^a Oriental College of Pharmacy   (India)

^b Department of Pharmaceutical Analysis and Quality Assurance   (India)

^c VNS Institute of Pharmacy   (India)

Author keywords

DSC; Minoxidil; Nanostructured lipid carrier; SEM

Indexed keywords

MINOXIDIL; NANOCARRIER; NANOSTRUCTURED LIPID CARRIER; UNCLASSIFIED DRUG;

ALOPECIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DISPERSION; DRUG FORMULATION; FEMALE; FLOW KINETICS; GEL; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; SKIN IRRITATION; ZETA POTENTIAL;

EID: 84884531054     PISSN: 13190164     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsps.2012.11.005     Document Type: Article

References (31)

1. Aronson J.K. Minoxidil. Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions 2006, 2354-2356. Elsevier, Amsterdam. J.K. Aronson (Ed.).
2. Atrux-Tallau N., Falson F., Pirot F. Nanotherapeutics for skin diseases. Nanotherapeutics: Drug Delivery Concepts in Nanoscience 2009, 125-161. Pan Stanford, Singapore. A. Lamprecht (Ed.).
3. Chaudhari Y.S. Nanoparticles - a paradigm for topical drug delivery. Chronicles of Young Scientists 2012, 3:82-85.
4. Chen Y., Zhou L., Yuan L., Zhang Z., Liu X., Wu Q. Formulation, characterization, and evaluation of in vitro skin permeation and in vivo pharmacodynamics of surface-charged tripterine-loaded nanostructured lipid carriers. International Journal of Nanomedicine 2012, 7:3023-3033.
5. Hommoss, A., 2008. Nanostructured lipid carriers (NLC). In: Dermal and Personal Care Formulations, Inaugural-Dissertation, Department of Biology, Chemistry and Pharmacy, Freie Universitat Berlin, p. 14.
6. Hu F.Q., Jiang S.P., Du Y.Z., Yuan H., Ye Y.Q., Zeng S. Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system. Colloids and Surfaces, B: Biointerfaces 2005, 45:167-173.
7. Jain P., Mishra A., Yadav S.K., Patil U.K., Baghel U.S. Formulation development and characterization of solid lipid nanoparticles containing nimesulide. International Journal of Drug Delivery Technology 2009, 1:24-27.
8. Jia L., Zhang D., Li Z., Feng F., Wang Y., Dai W., Duan C., Zhang Q. Preparation and characterization of silybin-loaded nanostructured lipid carriers. Drug Delivery 2010, 17(1):11-18.
9. Joshi M., Patravale V. Formulation and evaluation of nanostructured lipid carrier (NLC)-based Gel of Valdecoxib. Drug Development and Industrial Pharmacy 2006, 32:911-918.
10. Lim S.J., Kim C.K. Formulation parameters determining the physicochemical characteristics of solid lipid nanoparticles loaded with all-trans retinoic acid. International Journal of Pharmaceutics 2002, 243:135-146.
11. Liu J., Gong T., Wang C., Zhong Z., Zhang Z. Solid lipid nanoparticles loaded with insulin by sodium cholate-phosphatidylcholine-based mixed micelles: preparation and characterization. International Journal of Pharmaceutics 2007, 340:153-162.
12. Messenger A.G., Rundegren J. Minoxidil: mechanisms of action on hair growth. British Journal of Dermatology 2004, 150:186-194.
13. Muller, R.H., Almeida, A.J., 2005, SLN and NLC for Topical Antifungals for Drug Delivery, Inaugural-Dissertation, Department of Biology, Chemistry and Pharmacy, Freie Universitat Berlin, pp. 32-40.
14. Muller R.H., Ruh D., Runge S., Schulze-Forster K., Mehnert W. Cytotoxicity of solid lipid nanoparticles as a function of the lipid matrix and the surfactant. Pharmaceutical Research 1997, 14:458-462.
15. Muller, R.H., Mader, K., Lippacher, A., Jenning, V., 2000. Solid-liquid (semi-solid) liquid particles and method of producing highly concentrated lipid particle dispersions, in PCT/EP00/04565.
16. Muller R.H., Radtke M., Wissing S.A. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Advanced Drug Delivery Reviews 2002, 54:131-155.
17. Padoisa K., Cantienia C., Berthollea V., Bardel C., Pirot F., Falson F. Solid lipid nanoparticles suspension versus commercial solutions for dermal delivery of minoxidil. International Journal of Pharmaceutics 2011, 416:300-304.
18. Pardeike J., Hommoss A., Müller R.H. Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. International Journal of Pharmaceutics 2009, 366:170-184.
19. Rajashree H., Harshal G., Vilasrao K. Solid lipid nanoparticles and nanostructured lipid carriers: a review. Current Drug Therapy 2011, 6(4):240-250.
20. Sarmento B., Ferreira D., Veiga V., Ribeiro A. Characterization of insulin loaded alginate nanoparticles produced by ionotropic pregelation through DSC and FTIR studies. Carbohydrate Polymers 2006, 66:1-7.
21. Saupe A., Wissing S.A., Lenk A., Schmidt C., Müller R.H. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) - structural investigations on two different carrier systems. Bio-medical Materials and Engineering 2005, 15:393-402.
22. Souto E.B., Muller R.H. SLN and NLC for topical delivery of ketoconazole. Journal of Microencapsulation 2005, 22(5):501-510.
23. Teeranachaideekul V., Muller R.H., Junyaprasert V.B. Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC)-effects of formulation parameters on physicochemical stability. International Journal of Pharmaceutics 2007, 340:198-206.
24. Uner M., Yener G. Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives. International Journal of Nanomedicine 2007, 2(3):289-300.
25. Utreja S., Jain N.K. Solid lipid nanoparticles. Advances in Controlled and Novel Drug Delivery 2001, CBS Publishers, New Delhi, India, pp. 408-425.
26. Wagner L., Kenreigh C. Minoxidil. xPharm: The Comprehensive Pharmacology Reference 2007, 1-5. Elsevier, New York. S.J. Enna, B.B. David (Eds.).
27. Wang M., Jin Y., Yang Y., Zhao C., Yang H., Xu X., Qin X., Wang Z., Zang Z., Jian Y., Huang Y. In vivo biodistribution, anti-inflammatory, and hepatoprotective effects of liver targeting dexamethasone acetate loaded nanostructured lipid carrier system. International Journal of Nanomedicine 2010, 5:487-497.
28. Wissing S.A., Muller R.H. Solid lipid nanoparticles as carrier for sunscreens: in vitro release and in vivo skin penetration. Journal of Controlled Release 2002, 81:225-233.
29. Wissing S.A., Muller R.H. The influence of the crystallinity of lipid nanoparticles on their occlusive properties. International Journal of Pharmaceutics 2002, 242:377-379.
30. Wissing S.A., Muller R.H. The influence of solid lipid nanoparticles on skin hydration and viscoelasticity-in vivo study. European Journal of Pharmaceutics and Biopharmaceutics 2003, 56(1):67-72.
31. Zhao X., Yang C., Yang K., Li K., Hu H., Chen D. Preparation and characterization of nanostructured lipid carriers loaded traditional Chinese medicine, zedoary turmeric oil. Drug Development and Industrial Pharmacy 2010, 36(7):773-780.