Formulation, characterization, and evaluation of in vitro skin permeation and in vivo pharmacodynamics of surface-charged tripterine-loaded nanostructured lipid carriers

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 3023-3033

  Chen, Yan ^a   Zhou, Lei ^a   Yuan, Ling ^a   Zhang, Zhen hai ^a   Liu, Xuan ^a   Wu, Qingqing ^a  

^a KEY LABORATORY OF NEW DRUG DELIVERY SYSTEM OF CHINESE MATERIA MEDICA   (China)

Author keywords

Antimelanoma efficacy; Cellular uptake; Nanostructured lipid carriers; Percutaneous penetration; Surface charge; Tripterine

Indexed keywords

CELASTROL; DRUG CARRIER; NANOSTRUCTURED LIPID CARRIER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; CUTANEOUS MELANOMA; DRUG CYTOTOXICITY; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG UPTAKE; ENCAPSULATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PARTICLE SIZE; RAT; SKIN PERMEABILITY; SURFACE CHARGE; TUMOR VOLUME; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LIPIDS; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NANOPARTICLES; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; SKIN; SKIN ABSORPTION; STATIC ELECTRICITY; SURFACE PROPERTIES; TRITERPENES;

MUS;

EID: 84870366629     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S32476     Document Type: Article

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