Exploiting the burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology

Chemistry and Biology

Volumn 20, Issue 9, 2013, Pages 1147-1156

  Gourlay, Louise J ^a   Peri, Claudio ^b   Ferrer Navarro, Mario ^c   Conchillo Solé, Oscar ^c   Gori, Alessandro ^b   Rinchai, Darawan ^e   Thomas, Rachael J ^f   Champion, Olivia L ^f   Michell, Stephen L ^f   Kewcharoenwong, Chidchamai ^e   Nithichanon, Arnone ^e   Lassaux, Patricia ^a   Perletti, Lucia ^a   Longhi, Renato ^b   Lertmemongkolchai, Ganjana ^e   Titball, Richard W ^f   Daura, Xavier ^c,d   Colombo, Giorgio ^b   Bolognesi, Martino ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b CNR   (Italy)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^e KHON KAEN UNIVERSITY   (Thailand)

^f UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BPSL2765 ANTIGEN; EPITOPE; RECOMBINANT PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANTIBODY PRODUCTION; ANTIGEN ANTIBODY REACTION; ARTICLE; BACTERICIDAL ACTIVITY; BURKHOLDERIA PSEUDOMALLEI; CRYSTAL STRUCTURE; EPITOPE MAPPING; IN VITRO STUDY; MELIOIDOSIS; NONHUMAN; OPSONIZATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SERODIAGNOSIS; STRUCTURE ANALYSIS; VACCINATION;

ANTIBODIES; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BACTERIAL VACCINES; BURKHOLDERIA PSEUDOMALLEI; CRYSTALLOGRAPHY, X-RAY; EPITOPE MAPPING; EPITOPES; HUMANS; MOLECULAR DYNAMICS SIMULATION; NEUTROPHILS; PHAGOCYTOSIS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 84884519958     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2013.07.010     Document Type: Article

References (39)

1. C. Aagaard, T. Hoang, J. Dietrich, P.J. Cardona, A. Izzo, G. Dolganov, G.K. Schoolnik, J.P. Cassidy, R. Billeskov, and P. Andersen A multistage tuberculosis vaccine that confers efficient protection before and after exposure Nat. Med. 17 2011 189 194
2. H. Berendsen, J.R. Grigera, and T.P. Straatsma The missing term in effective pair potentials J. Phys. Chem. 91 1987 6269 6271
3. P.J. Brett, and D.E. Woods Structural and immunological characterization of Burkholderia pseudomallei O-polysaccharide-flagellin protein conjugates Infect. Immun. 64 1996 2824 2828
4. C.G. Bull The agglutination of bacteria in vivo J. Exp. Med. 22 1915 484 491
5. S. Chanchamroen, C. Kewcharoenwong, W. Susaengrat, M. Ato, and G. Lertmemongkolchai Human polymorphonuclear neutrophil responses to Burkholderia pseudomallei in healthy and diabetic subjects Infect. Immun. 77 2009 456 463
6. A.C. Cheng, and B.J. Currie Melioidosis: epidemiology, pathophysiology, and management Clin. Microbiol. Rev. 18 2005 383 416
7. J. Cuccui, T.S. Milne, N. Harmer, A.J. George, S.V. Harding, R.E. Dean, A.E. Scott, M. Sarkar-Tyson, B.W. Wren, R.W. Titball, and J.L. Prior Characterization of the Burkholderia pseudomallei K96243 capsular polysaccharide I coding region Infect. Immun. 80 2012 1209 1221
8. X. Daura, K. Gademann, B. Jaun, D. Seebach, W.F. Van Gunsteren, and A.E. Mark Peptide folding: When simulation meets experiment Angew. Chem. Int. Ed. Engl. 38 1999 236 240
9. P.R. Dormitzer, J.B. Ulmer, and R. Rappuoli Structure-based antigen design: a strategy for next generation vaccines Trends Biotechnol. 26 2008 659 667
10. A.M. Egan, and D.L. Gordon Burkholderia pseudomallei activates complement and is ingested but not killed by polymorphonuclear leukocytes Infect. Immun. 64 1996 4952 4959
11. P.L. Felgner, M.A. Kayala, A. Vigil, C. Burk, R. Nakajima-Sasaki, J. Pablo, D.M. Molina, S. Hirst, J.S. Chew, and D. Wang A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens Proc. Natl. Acad. Sci. USA 106 2009 13499 13504
12. S. Fiorucci, and M. Zacharias Prediction of protein-protein interaction sites using electrostatic desolvation profiles Biophys. J. 98 2010 1921 1930
13. Y. Fujita, and H. Taguchi Current status of multiple antigen-presenting peptide vaccine systems: Application of organic and inorganic nanoparticles Chem. Cent. J. 5 2011 48
14. Y. Hara, R. Mohamed, and S. Nathan Immunogenic Burkholderia pseudomallei outer membrane proteins as potential candidate vaccine targets PLoS ONE 4 2009 e6496
15. B. Hess, C. Kutzner, D. van der Spoel, and E. Lindahl GROMACS 4: algorithms for highly efficient load-balanced, and scalable molecular simulation J. Chem. Theory Comput. 4 2008 435 447
16. C. Koehler, L. Carlier, D. Veggi, E. Balducci, F. Di Marcello, M. Ferrer-Navarro, M. Pizza, X. Daura, M. Soriani, R. Boelens, and A.M. Bonvin Structural and biochemical characterization of NarE, an iron-containing ADP-ribosyltransferase from Neisseria meningitidis J. Biol. Chem. 286 2011 14842 14851
17. P. Lassaux, C. Peri, M. Ferrer-Navarro, L.J. Gourlay, A. Gori, O. Conchillo-Solé, D. Rinchai, G. Lertmemongkolchai, R. Longhi, and X. Daura A structure-based strategy for epitope discovery in Burkholderia pseudomallei OppA antigen Structure 21 2013 167 175
18. H. Li, X.P. Xiong, B. Peng, C.X. Xu, M.Z. Ye, T.C. Yang, S.Y. Wang, and X.X. Peng Identification of broad cross-protective immunogens using heterogeneous antiserum-based immunoproteomic approach J. Proteome Res. 8 2009 4342 4349
19. F.T. Liu, M. Zinnecker, T. Hamaoka, and D.H. Katz New procedures for preparation and isolation of conjugates of proteins and a synthetic copolymer of D-amino acids and immunochemical characterization of such conjugates Biochemistry 18 1979 690 693
20. M. Nelson, J.L. Prior, M.S. Lever, H.E. Jones, T.P. Atkins, and R.W. Titball Evaluation of lipopolysaccharide and capsular polysaccharide as subunit vaccines against experimental melioidosis J. Med. Microbiol. 53 2004 1177 1182
21. A. Nuccitelli, R. Cozzi, L.J. Gourlay, D. Donnarumma, F. Necchi, N. Norais, J.L. Telford, R. Rappuoli, M. Bolognesi, and D. Maione Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections Proc. Natl. Acad. Sci. USA 108 2011 10278 10283
22. A.A. Pal'tsyn, E.G. Kolokol'chikova, A.K. Badikova, N.V. Chervonskaia, and I.A. Grishina [The role of agglutination during bacterial infection] Biull. Eksp. Biol. Med. 127 1999 4 8
23. L.M. Parsons, F. Lin, and J. Orban Peptidoglycan recognition by Pal, an outer membrane lipoprotein Biochemistry 45 2006 2122 2128
24. S.J. Peacock, D. Limmathurotsakul, Y. Lubell, G.C. Koh, L.J. White, N.P. Day, and R.W. Titball Melioidosis vaccines: a systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes PLoS Negl. Trop. Dis. 6 2012 e1488
25. C. Peri, P. Gagni, F. Combi, A. Gori, M. Chiari, R. Longhi, M. Cretich, and G. Colombo Rational epitope design for protein targeting ACS Chem. Biol. 8 2013 397 404
26. A.W. Purcell, J. McCluskey, and J. Rossjohn More than one reason to rethink the use of peptides in vaccine design Nat. Rev. Drug Discov. 6 2007 404 414
27. S.L. Reckseidler-Zenteno, R. DeVinney, and D.E. Woods The capsular polysaccharide of Burkholderia pseudomallei contributes to survival in serum by reducing complement factor C3b deposition Infect. Immun. 73 2005 1106 1115
28. M. Sarkar-Tyson, and R.W. Titball Progress toward development of vaccines against melioidosis: A review Clin. Ther. 32 2010 1437 1445
29. G. Scarabelli, G. Morra, and G. Colombo Predicting interaction sites from the energetics of isolated proteins: a new approach to epitope mapping Biophys. J. 98 2010 1966 1975
30. M. Soriani, P. Petit, R. Grifantini, R. Petracca, G. Gancitano, E. Frigimelica, F. Nardelli, C. Garcia, S. Spinelli, and G. Scarabelli Exploiting antigenic diversity for vaccine design: the chlamydia ArtJ paradigm J. Biol. Chem. 285 2010 30126 30138
31. Y.C. Su, K.L. Wan, R. Mohamed, and S. Nathan Immunization with the recombinant Burkholderia pseudomallei outer membrane protein Omp85 induces protective immunity in mice Vaccine 28 2010 5005 5011
32. D. Suwannasaen, J. Mahawantung, W. Chaowagul, D. Limmathurotsakul, P.L. Felgner, H. Davies, G.J. Bancroft, R.W. Titball, and G. Lertmemongkolchai Human immune responses to Burkholderia pseudomallei characterized by protein microarray analysis J. Infect. Dis. 203 2011 1002 1011
33. W.F. van Gunsteren, D. Bakowies, R. Baron, I. Chandrasekhar, M. Christen, X. Daura, P. Gee, D.P. Geerke, A. Glättli, and P.H. Hünenberger Biomolecular modeling: goals, problems, perspectives Angew. Chem. Int. Ed. Engl. 45 2006 4064 4092
34. M.E. Wand, C.M. Müller, R.W. Titball, and S.L. Michell Macrophage and Galleria mellonella infection models reflect the virulence of naturally occurring isolates of B. pseudomallei, B. thailandensis and B. oklahomensis BMC Microbiol. 11 2011 11
35. J.N. Weiser, and E.C. Gotschlich Outer membrane protein A (OmpA) contributes to serum resistance and pathogenicity of Escherichia coli K-1 Infect. Immun. 59 1991 2252 2258
36. E. Westhof, D. Altschuh, D. Moras, A.C. Bloomer, A. Mondragon, A. Klug, and M.H. Van Regenmortel Correlation between segmental mobility and the location of antigenic determinants in proteins Nature 311 1984 123 126
37. W.J. Wiersinga, T. van der Poll, N.J. White, N.P. Day, and S.J. Peacock Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei Nat. Rev. Microbiol. 4 2006 272 282
38. M.E. Woodman, R.G. Worth, and R.M. Wooten Capsule influences the deposition of critical complement C3 levels required for the killing of Burkholderia pseudomallei via NADPH-oxidase induction by human neutrophils PLoS ONE 7 2012 e52276
39. S. Zhang, S.H. Feng, B. Li, H.Y. Kim, J. Rodriguez, S. Tsai, and S.C. Lo In vitro and in vivo studies of monoclonal antibodies with prominent bactericidal activity against Burkholderia pseudomallei and Burkholderia mallei Clin. Vaccine Immunol. 18 2011 825 834