Ibrutinib in relapsed chronic lymphocytic leukemia [5]

New England Journal of Medicine

Volumn 369, Issue 13, 2013, Pages 1277-1279

  Neffendorf, James E ^a   Gout, Irina ^a   Hildebrand, G Darius ^a  

^a KING EDWARD VII HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IBRUTINIB; ANTINEOPLASTIC AGENT; PROTEIN TYROSINE KINASE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; ADENOSINE DIPHOSPHATE; ARACHIDONIC ACID; BRUTON TYROSINE KINASE; COLLAGEN; THROMBIN RECEPTOR ACTIVATING PEPTIDE 6;

AGED; CASE REPORT; CATARACT; CHRONIC LYMPHATIC LEUKEMIA; FEMALE; HUMAN; LENS DISEASE; LETTER; LEUKEMIA RELAPSE; PHENOTYPE; PRIORITY JOURNAL; SLIT LAMP; VISUAL ACUITY; VISUAL IMPAIRMENT; DRUG ANTAGONISM; MALE; NOTE; CONCENTRATION RESPONSE; DRUG CYTOTOXICITY; DRUG SAFETY; IC 50; LYMPHOPROLIFERATIVE DISEASE; MANTLE CELL LYMPHOMA; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE FUNCTION;

ANTINEOPLASTIC AGENTS; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; PROTEIN-TYROSINE KINASES; PYRAZOLES; PYRIMIDINES;

EID: 84884512701     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc1309710     Document Type: Letter

References (4)

1. Byrd JC, Furman RR, Coutre SE, et al. Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia. N Engl J Med 2013;369:32-42.
2. Zhou YP, He YT, Chen CL, et al. Time-specific blockade of PDGFR with imatinib (Glivec) causes cataract and disruption of lens fiber cells in neonatal mice. Virchows Arch 2011;458:349-56.
3. Son AI, Park JE, Zhou R. The role of Eph receptors in lens function and disease. Sci China Life Sci 2012;55:434-43.
4. Park JE, Son AI, Hua R, Wang L, Zhang X, Zhou R. Human cataract mutations in EPHA2 SAM domain alter receptor stability and function. PLoS One 2012;7(5):e36564.