-
1
-
-
81855218186
-
Intestinal stertransporters and cholesterol absorption inhibition
-
Davis H.R., Tershakovec A.M., Tomassini J.E., Musliner T. Intestinal sterol transporters and cholesterol absorption inhibition. Curr Opin Lipidol 2011, 22:467-478.
-
(2011)
Curr Opin Lipidol
, vol.22
, pp. 467-478
-
-
Davis, H.R.1
Tershakovec, A.M.2
Tomassini, J.E.3
Musliner, T.4
-
2
-
-
0037044454
-
Inhibition of intestinal cholesterol absorption by ezetimibe in humans
-
Sudhop T., Lutjohann D., Kodal A., et al. Inhibition of intestinal cholesterol absorption by ezetimibe in humans. Circulation 2002, 106:1943-1948.
-
(2002)
Circulation
, vol.106
, pp. 1943-1948
-
-
Sudhop, T.1
Lutjohann, D.2
Kodal, A.3
-
3
-
-
70350370453
-
Changes in cholesterol absorption and cholesterol synthesis caused by ezetimibe and/or simvastatin in men
-
Sudhop T., Reber M., Tribble D., et al. Changes in cholesterol absorption and cholesterol synthesis caused by ezetimibe and/or simvastatin in men. JLipid Res 2009, 50:2117-2123.
-
(2009)
JLipid Res
, vol.50
, pp. 2117-2123
-
-
Sudhop, T.1
Reber, M.2
Tribble, D.3
-
4
-
-
84884509981
-
-
Merck & Co., Inc, Whitehouse Station, NJ
-
Zetia [product insert] 2012, Merck & Co., Inc, Whitehouse Station, NJ.
-
(2012)
Zetia [product insert]
-
-
-
5
-
-
33646442215
-
Effect of ezetimibe on the invivo kinetics of apoB-48 and apoB-100 in men with primary hypercholesterolemia
-
Tremblay A.J., Lamarche B., Cohn J.S., Hogue J.C., Couture P. Effect of ezetimibe on the invivo kinetics of apoB-48 and apoB-100 in men with primary hypercholesterolemia. Arterioscler Thromb Vasc Biol 2006, 26:1101-1106.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1101-1106
-
-
Tremblay, A.J.1
Lamarche, B.2
Cohn, J.S.3
Hogue, J.C.4
Couture, P.5
-
6
-
-
67650552637
-
Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia
-
Tremblay A.J., Lamarche B., Hogue J.C., Couture P. Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia. JLipid Res 2009, 50:1463-1471.
-
(2009)
JLipid Res
, vol.50
, pp. 1463-1471
-
-
Tremblay, A.J.1
Lamarche, B.2
Hogue, J.C.3
Couture, P.4
-
7
-
-
46249110108
-
Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages
-
Sehayek E., Hazen S.L. Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages. Arterioscler Thromb Vasc Biol 2008, 28:1296-1297.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1296-1297
-
-
Sehayek, E.1
Hazen, S.L.2
-
8
-
-
70349563838
-
Both the peroxisome proliferator-activated receptor delta agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol
-
Briand F., Naik S.U., Fuki I., et al. Both the peroxisome proliferator-activated receptor delta agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol. Clin Transl Sci 2009, 2:127-133.
-
(2009)
Clin Transl Sci
, vol.2
, pp. 127-133
-
-
Briand, F.1
Naik, S.U.2
Fuki, I.3
-
9
-
-
84876288577
-
Ezetimibe inhibits hepatic Niemann-Pick C1-Like 1 to facilitate macrophage reverse cholesterol transport in mice
-
Xie P., Jia L., Ma Y., et al. Ezetimibe inhibits hepatic Niemann-Pick C1-Like 1 to facilitate macrophage reverse cholesterol transport in mice. Arterioscler Thromb Vasc Biol 2013, 33:920-925.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 920-925
-
-
Xie, P.1
Jia, L.2
Ma, Y.3
-
10
-
-
79953036831
-
Effects of ezetimibe on atherosclerosis in preclinical models
-
Davis H.R., Lowe R.S., Neff D.R. Effects of ezetimibe on atherosclerosis in preclinical models. Atherosclerosis 2011, 215:266-278.
-
(2011)
Atherosclerosis
, vol.215
, pp. 266-278
-
-
Davis, H.R.1
Lowe, R.S.2
Neff, D.R.3
-
11
-
-
33646362257
-
Intestinal cholesterol absorption inhibitor ezetimibe added to cholestyramine for sitosterolemia and xanthomatosis
-
Salen G., Starc T., Sisk C.M., Patel S.B. Intestinal cholesterol absorption inhibitor ezetimibe added to cholestyramine for sitosterolemia and xanthomatosis. Gastroenterology 2006, 130:1853-1857.
-
(2006)
Gastroenterology
, vol.130
, pp. 1853-1857
-
-
Salen, G.1
Starc, T.2
Sisk, C.M.3
Patel, S.B.4
-
12
-
-
40649098464
-
The role of Niemann-Pick C1-Like 1 (NPC1L1) in intestinal sterol absorption
-
Turley S.D. The role of Niemann-Pick C1-Like 1 (NPC1L1) in intestinal sterol absorption. JClin Lipidol 2008, 2:S20-S28.
-
(2008)
JClin Lipidol
, vol.2
-
-
Turley, S.D.1
-
13
-
-
33751006139
-
Emerging roles of the intestine in control of cholesterol metabolism
-
Kruit J.K., Groen A.K., van Berkel T.J., Kuipers F. Emerging roles of the intestine in control of cholesterol metabolism. World J Gastroenterol 2006, 12:6429-6439.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 6429-6439
-
-
Kruit, J.K.1
Groen, A.K.2
van Berkel, T.J.3
Kuipers, F.4
-
15
-
-
84869991362
-
Measurement of reverse cholesterol transport pathways in humans: invivo rates of free cholesterol efflux, esterification, and excretion
-
Turner S., Voogt J., Davidson M., et al. Measurement of reverse cholesterol transport pathways in humans: invivo rates of free cholesterol efflux, esterification, and excretion. JAm Heart Assoc 2012, 1:e001826.
-
(2012)
JAm Heart Assoc
, vol.1
-
-
Turner, S.1
Voogt, J.2
Davidson, M.3
-
16
-
-
84879003004
-
Invivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1
-
Holleboom A.G., Jakulj L., Franssen R., et al. Invivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1. JLipid Res 2013, 10.1194/jlr.P028449.
-
(2013)
JLipid Res
-
-
Holleboom, A.G.1
Jakulj, L.2
Franssen, R.3
-
18
-
-
79959261143
-
2)O: enabling back-to-back studies in the same subject
-
2)O: enabling back-to-back studies in the same subject. JLipid Res 2011, 52:1420-1428.
-
(2011)
JLipid Res
, vol.52
, pp. 1420-1428
-
-
Previs, S.F.1
Mahsut, A.2
Kulick, A.3
-
19
-
-
0027400822
-
Cholesterol kinetics insubjects with bile fistula. Positive relationship between size of the bileacid precursor pool and bile acid synthetic rate
-
Schwartz C.C., Zech L.A., Vandenbroek J.M., Cooper P.S. Cholesterol kinetics insubjects with bile fistula. Positive relationship between size of the bileacid precursor pool and bile acid synthetic rate. JClin Invest 1993, 91:923-938.
-
(1993)
JClin Invest
, vol.91
, pp. 923-938
-
-
Schwartz, C.C.1
Zech, L.A.2
Vandenbroek, J.M.3
Cooper, P.S.4
-
20
-
-
4544331579
-
Lipoprotein cholesteryl ester production, transfer, and output invivo in humans
-
Schwartz C.C., Vandenbroek J.M., Cooper P.S. Lipoprotein cholesteryl ester production, transfer, and output invivo in humans. JLipid Res 2004, 45:1594-1607.
-
(2004)
JLipid Res
, vol.45
, pp. 1594-1607
-
-
Schwartz, C.C.1
Vandenbroek, J.M.2
Cooper, P.S.3
-
21
-
-
68749102069
-
Ezetimibe reduces plaque inflammation in a rabbit model of atherosclerosis and inhibits monocyte migration in addition to its lipid-lowering effect
-
Gomez-Garre D., Munoz-Pacheco P., Gonzalez-Rubio M., Aragoncillo P., Granados R., Fernandez-Cruz A. Ezetimibe reduces plaque inflammation in a rabbit model of atherosclerosis and inhibits monocyte migration in addition to its lipid-lowering effect. Br J Pharmacol 2009, 156:1218-1227.
-
(2009)
Br J Pharmacol
, vol.156
, pp. 1218-1227
-
-
Gomez-Garre, D.1
Munoz-Pacheco, P.2
Gonzalez-Rubio, M.3
Aragoncillo, P.4
Granados, R.5
Fernandez-Cruz, A.6
-
22
-
-
30844437481
-
Inhibition of cholesterol absorption by the combination of dietary plant sterols and ezetimibe: effects on plasma lipid levels
-
Jakulj L., Trip M.D., Sudhop T., von Bergmann K., Kastelein J.J., Vissers M.N. Inhibition of cholesterol absorption by the combination of dietary plant sterols and ezetimibe: effects on plasma lipid levels. JLipid Res 2005, 46:2692-2698.
-
(2005)
JLipid Res
, vol.46
, pp. 2692-2698
-
-
Jakulj, L.1
Trip, M.D.2
Sudhop, T.3
von Bergmann, K.4
Kastelein, J.J.5
Vissers, M.N.6
-
23
-
-
77955653676
-
Ezetimibe stimulates faecal neutral sterol excretion depending on abcg8 function in mice
-
Jakulj L., Vissers M.N., van Roomen C.P., et al. Ezetimibe stimulates faecal neutral sterol excretion depending on abcg8 function in mice. FEBS Lett 2010, 584:3625-3628.
-
(2010)
FEBS Lett
, vol.584
, pp. 3625-3628
-
-
Jakulj, L.1
Vissers, M.N.2
van Roomen, C.P.3
-
24
-
-
44449103671
-
Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches
-
deGoma E.M., Degoma R.L., Rader D.J. Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches. JAm Coll Cardiol 2008, 51:2199-2211.
-
(2008)
JAm Coll Cardiol
, vol.51
, pp. 2199-2211
-
-
deGoma, E.M.1
Degoma, R.L.2
Rader, D.J.3
-
25
-
-
0035831089
-
The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys
-
Van Heek M., Compton D.S., Davis H.R. The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys. Eur J Pharmacol 2001, 415:79-84.
-
(2001)
Eur J Pharmacol
, vol.415
, pp. 79-84
-
-
Van Heek, M.1
Compton, D.S.2
Davis, H.R.3
-
26
-
-
32544443164
-
REVIEW: efficacy and mechanisms of action of statins in thetreatment of diabetic dyslipidemia
-
Ginsberg H.N. REVIEW: efficacy and mechanisms of action of statins in thetreatment of diabetic dyslipidemia. JClin Endocrinol Metab 2006, 91:383-392.
-
(2006)
JClin Endocrinol Metab
, vol.91
, pp. 383-392
-
-
Ginsberg, H.N.1
-
27
-
-
38549168453
-
Effects of ezetimibe, simvastatin, atorvastatin, and ezetimibe-statin therapies on non-cholesterol sterols in patients with primary hypercholesterolemia
-
Assmann G., Kannenberg F., Ramey D.R., Musliner T.A., Gutkin S.W., Veltri E.P. Effects of ezetimibe, simvastatin, atorvastatin, and ezetimibe-statin therapies on non-cholesterol sterols in patients with primary hypercholesterolemia. Curr Med Res Opin 2008, 24:249-259.
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 249-259
-
-
Assmann, G.1
Kannenberg, F.2
Ramey, D.R.3
Musliner, T.A.4
Gutkin, S.W.5
Veltri, E.P.6
-
28
-
-
21744457262
-
Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption
-
Repa J.J., Turley S.D., Quan G., Dietschy J.M. Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption. JLipid Res 2005, 46:779-789.
-
(2005)
JLipid Res
, vol.46
, pp. 779-789
-
-
Repa, J.J.1
Turley, S.D.2
Quan, G.3
Dietschy, J.M.4
-
29
-
-
1442335817
-
Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia
-
Salen G., von Bergmann K., Lutjohann D., et al. Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia. Circulation 2004, 109:966-971.
-
(2004)
Circulation
, vol.109
, pp. 966-971
-
-
Salen, G.1
von Bergmann, K.2
Lutjohann, D.3
-
30
-
-
72049129430
-
Extended-release niacin or ezetimibe and carotid intima-media thickness
-
Taylor A.J., Villines T.C., Stanek E.J., et al. Extended-release niacin or ezetimibe and carotid intima-media thickness. NEngl J Med 2009, 361:2113-2122.
-
(2009)
NEngl J Med
, vol.361
, pp. 2113-2122
-
-
Taylor, A.J.1
Villines, T.C.2
Stanek, E.J.3
-
31
-
-
26444537961
-
Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 cells treated with ezetimibe
-
During A., Dawson H.D., Harrison E.H. Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 cells treated with ezetimibe. JNutr 2005, 135:2305-2312.
-
(2005)
JNutr
, vol.135
, pp. 2305-2312
-
-
During, A.1
Dawson, H.D.2
Harrison, E.H.3
-
32
-
-
74549210093
-
Model system for the analysis of cell surface expression of human ABCA1
-
Kasza I., Hegyi Z., Szabo K., et al. Model system for the analysis of cell surface expression of human ABCA1. BMC Cell Biol 2009, 10:93.
-
(2009)
BMC Cell Biol
, vol.10
, pp. 93
-
-
Kasza, I.1
Hegyi, Z.2
Szabo, K.3
-
33
-
-
34548620629
-
Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles
-
Labonte E.D., Howles P.N., Granholm N.A., et al. Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles. Biochim Biophys Acta 2007, 1771:1132-1139.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 1132-1139
-
-
Labonte, E.D.1
Howles, P.N.2
Granholm, N.A.3
-
34
-
-
34548182369
-
Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells
-
Field F.J., Watt K., Mathur S.N. Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells. JLipid Res 2007, 48:1735-1745.
-
(2007)
JLipid Res
, vol.48
, pp. 1735-1745
-
-
Field, F.J.1
Watt, K.2
Mathur, S.N.3
-
35
-
-
59649098119
-
Origins of intestinal ABCA1-mediated HDL-cholesterol
-
Field F.J., Watt K., Mathur S.N. Origins of intestinal ABCA1-mediated HDL-cholesterol. JLipid Res 2008, 49:2605-2619.
-
(2008)
JLipid Res
, vol.49
, pp. 2605-2619
-
-
Field, F.J.1
Watt, K.2
Mathur, S.N.3
-
36
-
-
0030951706
-
Theoretical considerations of what regulates low-density-lipoprotein and high-density-lipoprotein cholesterol
-
Dietschy J.M. Theoretical considerations of what regulates low-density-lipoprotein and high-density-lipoprotein cholesterol. Am J Clin Nutr 1997, 65:1581S-1589S.
-
(1997)
Am J Clin Nutr
, vol.65
-
-
Dietschy, J.M.1
-
37
-
-
79959746706
-
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial
-
Baigent C., Landray M.J., Reith C., et al. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. Lancet 2011, 377:2181-2192.
-
(2011)
Lancet
, vol.377
, pp. 2181-2192
-
-
Baigent, C.1
Landray, M.J.2
Reith, C.3
-
38
-
-
78449281377
-
Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials
-
Baigent C., Blackwell L., Emberson J., et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials. Lancet 2010, 376:1670-1681.
-
(2010)
Lancet
, vol.376
, pp. 1670-1681
-
-
Baigent, C.1
Blackwell, L.2
Emberson, J.3
-
39
-
-
77951622890
-
An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design
-
Califf R.M., Lokhnygina Y., Cannon C.P., et al. An update on the IMProved reduction of outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design. Am Heart J 2010, 159:705-709.
-
(2010)
Am Heart J
, vol.159
, pp. 705-709
-
-
Califf, R.M.1
Lokhnygina, Y.2
Cannon, C.P.3
-
40
-
-
43049183509
-
Ezetimibe: cholesterol lowering and beyond
-
Bays H.E., Neff D., Tomassini J.E., Tershakovec A.M. Ezetimibe: cholesterol lowering and beyond. Expert Rev Cardiovasc Ther 2008, 6:447-470.
-
(2008)
Expert Rev Cardiovasc Ther
, vol.6
, pp. 447-470
-
-
Bays, H.E.1
Neff, D.2
Tomassini, J.E.3
Tershakovec, A.M.4
|