Cellular retinaldehyde binding protein - Different binding modes and micro-solvation patterns for high-affinity 9-cis- and 11-cis-retinal substrates

Journal of Physical Chemistry B

Volumn 117, Issue 37, 2013, Pages 10719-10729

  Helbling, Rachel E ^a   Bolze, Christin S ^a   Golczak, Marcin ^b   Palczewski, Krzysztof ^b   Stocker, Achim ^a   Cascella, Michele ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; LIGANDS; MOLECULAR DYNAMICS; PROTEINS; SOLVATION;

BINDING CONFORMATIONS; BINDING GEOMETRIES; ISOMERASE ACTIVITY; MOLECULAR DYNAMICS SIMULATIONS; SEMI-EMPIRICAL METHODS; SOLVATION PATTERNS; STRUCTURAL ELEMENTS; VERY LOW TEMPERATURES;

OPHTHALMOLOGY;

11 CIS RETINAL BINDING PROTEIN; 11-CIS-RETINAL-BINDING PROTEIN; 9 CIS RETINAL; 9,13 DICIS RETINAL; 9,13-DICIS-RETINAL; 9-CIS-RETINAL; CARRIER PROTEIN; DRUG DERIVATIVE; RETINAL;

ARTICLE; CHEMISTRY; EYE DISEASE; GENETICS; HUMAN; METABOLISM; MOLECULAR DYNAMICS; MUTATION; PROTEIN CONFORMATION; RETINA DISEASE;

CARRIER PROTEINS; EYE DISEASES, HEREDITARY; HUMANS; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN CONFORMATION; RETINAL DISEASES; RETINALDEHYDE;

EID: 84884506578     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp405410t     Document Type: Article

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