Identification of diterpene alkaloids from Aconitum napellus subsp. firmum and GIRK channel activities of some Aconitum alkaloids

Fitoterapia

Volumn 90, Issue , 2013, Pages 85-93

  Kiss, Tivadar ^a   Orvos, Péter ^a,b   Bánsághi, Száva ^b   Forgo, Peter ^a   Jedlinszki, Nikoletta ^a   Tálosi, László ^b   Hohmann, Judit ^a   Csupor, Dezso ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

^b Rytmion Ltd   (Hungary)

Author keywords

Aconitum napellus L. subsp. Firmum; Cardiovascular ion channels; Diterpene alkaloids; GIRK; hERG

Indexed keywords

ACONITINE; ACONITUM NAPELLUS EXTRACT; ALKALOID DERIVATIVE; DITERPENE; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; ISOTALATIZIDINE; KARAKOLINE; NAPELLINE; NEOLINE; PLANT EXTRACT; POTASSIUM CHANNEL HERG; SENBUSINE C; TAURENINE; UNCLASSIFIED DRUG;

ACONITUM NAPELLUS; ARTICLE; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; ELECTROPHYSIOLOGY; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; ION CURRENT; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PATCH CLAMP; PRIORITY JOURNAL; SCREENING;

ACONITUM NAPELLUS L. SUBSP. FIRMUM; CARDIOVASCULAR ION CHANNELS; DITERPENE ALKALOIDS; GIRK; HERG;

ACONITINE; ACONITUM; ETHER-A-GO-GO POTASSIUM CHANNELS; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; HEK293 CELLS; HUMANS; MOLECULAR STRUCTURE; PLANT EXTRACTS; POTASSIUM CHANNEL BLOCKERS; RANUNCULACEAE;

EID: 84884468718     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2013.07.010     Document Type: Article

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