메뉴 건너뛰기




Volumn 44, Issue 10, 2013, Pages 2097-2105

The nuclear protein expression levels of SNAI1 and ZEB1 are involved in the progression and lymph node metastasis of cervical cancer via the epithelial-mesenchymal transition pathway

Author keywords

Cervical cancer; Epithelial mesenchymal transition (EMT); SNAI1; Vimentin; ZEB1

Indexed keywords

NUCLEAR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SNAI1; TRANSCRIPTION FACTOR ZEB1; UNCLASSIFIED DRUG; VIMENTIN;

EID: 84884414149     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2013.04.001     Document Type: Article
Times cited : (48)

References (33)
  • 2
    • 84863011646 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cervical carcinoma
    • M.Y. Lee, and M.R. Shen Epithelial-mesenchymal transition in cervical carcinoma Am J Transl Res 2012 1 13
    • (2012) Am J Transl Res , pp. 1-13
    • Lee, M.Y.1    Shen, M.R.2
  • 3
    • 51049109014 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cervical cancer: Correlation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation
    • M.Y. Lee, C.Y. Chou, M.J. Tang, and M.R. Shen Epithelial-mesenchymal transition in cervical cancer: correlation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation Clin Cancer Res 14 2008 4743 4750
    • (2008) Clin Cancer Res , vol.14 , pp. 4743-4750
    • Lee, M.Y.1    Chou, C.Y.2    Tang, M.J.3    Shen, M.R.4
  • 4
    • 46049120814 scopus 로고    scopus 로고
    • ZEB1 expression in type i vs type II endometrial cancers: A marker of aggressive disease
    • M. Singh, N.S. Spoelstra, and A. Jean ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease Mod Pathol 21 2008 912 923
    • (2008) Mod Pathol , vol.21 , pp. 912-923
    • Singh, M.1    Spoelstra, N.S.2    Jean, A.3
  • 5
    • 42049092980 scopus 로고    scopus 로고
    • Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells
    • T.R. Graham, H.E. Zhau, and V.A. Odero-Marah Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells Cancer Res 68 2008 2479 2488
    • (2008) Cancer Res , vol.68 , pp. 2479-2488
    • Graham, T.R.1    Zhau, H.E.2    Odero-Marah, V.A.3
  • 6
    • 65249101685 scopus 로고    scopus 로고
    • ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells
    • J.M. Drake, G. Strohbehn, T.B. Bair, J.G. Moreland, and M.D. Henry ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells Mol Biol Cell 20 2009 2207 2217
    • (2009) Mol Biol Cell , vol.20 , pp. 2207-2217
    • Drake, J.M.1    Strohbehn, G.2    Bair, T.B.3    Moreland, J.G.4    Henry, M.D.5
  • 7
    • 54949147234 scopus 로고    scopus 로고
    • Expression of the ZEB1 (deltaEF1) transcription factor in human: Additional insights
    • E.M. Hurt, J.N. Saykally, B.M. Anose, K.R. Kalli, and M.M. Sanders Expression of the ZEB1 (deltaEF1) transcription factor in human: additional insights Mol Cell Biochem 318 2008 89 99
    • (2008) Mol Cell Biochem , vol.318 , pp. 89-99
    • Hurt, E.M.1    Saykally, J.N.2    Anose, B.M.3    Kalli, K.R.4    Sanders, M.M.5
  • 8
    • 85045351899 scopus 로고    scopus 로고
    • Snail negatively regulates cell adhesion to extracellular matrix and integrin expression via the MAPK pathway in prostate cancer cells
    • C.L. Neal, D. McKeithen, and V.A. Odero-Marah Snail negatively regulates cell adhesion to extracellular matrix and integrin expression via the MAPK pathway in prostate cancer cells Cell Adh Migr 5 2011 249 257
    • (2011) Cell Adh Migr , vol.5 , pp. 249-257
    • Neal, C.L.1    McKeithen, D.2    Odero-Marah, V.A.3
  • 9
    • 0037131409 scopus 로고    scopus 로고
    • Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression
    • S. Guaita, I. Puig, and C. Franci Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression J Biol Chem 277 2002 39209 39216
    • (2002) J Biol Chem , vol.277 , pp. 39209-39216
    • Guaita, S.1    Puig, I.2    Franci, C.3
  • 10
    • 84859350804 scopus 로고    scopus 로고
    • Correlation of epithelial-mesenchymal transition markers with clinicopathologic parameters in adenocarcinomas and squamous cell carcinoma of the lung
    • S.H. Kim, J.M. Kim, and M.H. Shin Correlation of epithelial-mesenchymal transition markers with clinicopathologic parameters in adenocarcinomas and squamous cell carcinoma of the lung Histol Histopathol 27 2012 581 591
    • (2012) Histol Histopathol , vol.27 , pp. 581-591
    • Kim, S.H.1    Kim, J.M.2    Shin, M.H.3
  • 11
    • 73949087260 scopus 로고    scopus 로고
    • Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1
    • I. Ota, X.Y. Li, Y. Hu, and S.J. Weiss Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1 Proc Natl Acad Sci U S A 106 2009 20318 20323
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 20318-20323
    • Ota, I.1    Li, X.Y.2    Hu, Y.3    Weiss, S.J.4
  • 12
    • 79952772897 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 cooperates with transcription factor Snail to induce epithelial-mesenchymal transition
    • C.Y. Lin, P.H. Tsai, and C.C. Kandaswami Matrix metalloproteinase-9 cooperates with transcription factor Snail to induce epithelial-mesenchymal transition Cancer Sci 102 2011 815 827
    • (2011) Cancer Sci , vol.102 , pp. 815-827
    • Lin, C.Y.1    Tsai, P.H.2    Kandaswami, C.C.3
  • 13
    • 85047698213 scopus 로고    scopus 로고
    • Correlation of Snail expression with histological grade and lymph node status in breast carcinomas
    • M.J. Blanco, G. Moreno-Bueno, and D. Sarrio Correlation of Snail expression with histological grade and lymph node status in breast carcinomas Oncogene 21 2002 3241 3246
    • (2002) Oncogene , vol.21 , pp. 3241-3246
    • Blanco, M.J.1    Moreno-Bueno, G.2    Sarrio, D.3
  • 14
    • 0029804487 scopus 로고    scopus 로고
    • Vimentin expression in cervical carcinomas: Association with invasive and migratory potential
    • C. Gilles, M. Polette, and J. Piette Vimentin expression in cervical carcinomas: association with invasive and migratory potential J Pathol 180 1996 175 180
    • (1996) J Pathol , vol.180 , pp. 175-180
    • Gilles, C.1    Polette, M.2    Piette, J.3
  • 15
    • 77954095184 scopus 로고    scopus 로고
    • Vimentin expression in the cervix
    • C.J. Stewart, and L. Little Vimentin expression in the cervix Int J Gynecol Pathol 29 2010 402 403
    • (2010) Int J Gynecol Pathol , vol.29 , pp. 402-403
    • Stewart, C.J.1    Little, L.2
  • 16
    • 84863981376 scopus 로고    scopus 로고
    • Significance of E-cadherin, beta-catenin, and vimentin expression as postoperative prognosis indicators in cervical squamous cell carcinoma
    • Y. Cheng, Y. Zhou, and W. Jiang Significance of E-cadherin, beta-catenin, and vimentin expression as postoperative prognosis indicators in cervical squamous cell carcinoma Hum Pathol 43 2012 1213 1220
    • (2012) Hum Pathol , vol.43 , pp. 1213-1220
    • Cheng, Y.1    Zhou, Y.2    Jiang, W.3
  • 17
    • 0031749594 scopus 로고    scopus 로고
    • Is the invasive front of an oral carcinoma the most important area for prognostication?
    • M. Bryne Is the invasive front of an oral carcinoma the most important area for prognostication? Oral Dis 4 1998 70 77
    • (1998) Oral Dis , vol.4 , pp. 70-77
    • Bryne, M.1
  • 18
    • 0030960750 scopus 로고    scopus 로고
    • Prognostic value of histobiological factors (malignancy grading and AgNor content) assessed at the invasive tumour front of oral squamous cell carcinomas
    • J. Piffko, A. Bankfalvi, and D. Ofner Prognostic value of histobiological factors (malignancy grading and AgNor content) assessed at the invasive tumour front of oral squamous cell carcinomas Br J Cancer 75 1997 1543 1546
    • (1997) Br J Cancer , vol.75 , pp. 1543-1546
    • Piffko, J.1    Bankfalvi, A.2    Ofner, D.3
  • 19
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • H. Peinado, D. Olmeda, and A. Cano Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7 2007 415 428
    • (2007) Nat Rev Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 20
    • 0022479541 scopus 로고
    • Immunohistochemical analyses of estrogen receptor in endometrial adenocarcinoma using a monoclonal antibody
    • D.A. Budwit-Novotny, K.S. McCarty, and E.B. Cox Immunohistochemical analyses of estrogen receptor in endometrial adenocarcinoma using a monoclonal antibody Cancer Res 46 1986 5419 5425
    • (1986) Cancer Res , vol.46 , pp. 5419-5425
    • Budwit-Novotny, D.A.1    McCarty, K.S.2    Cox, E.B.3
  • 21
    • 79960423794 scopus 로고    scopus 로고
    • Nuclear Snail1 and nuclear ZEB1 protein expression in invasive and intraductal human breast carcinomas
    • J. Geradts, A.G. de Herreros, Z. Su, J. Burchette, G. Broadwater, and R.E. Bachelder Nuclear Snail1 and nuclear ZEB1 protein expression in invasive and intraductal human breast carcinomas Hum Pathol 42 2011 1125 1131
    • (2011) Hum Pathol , vol.42 , pp. 1125-1131
    • Geradts, J.1    De Herreros, A.G.2    Su, Z.3    Burchette, J.4    Broadwater, G.5    Bachelder, R.E.6
  • 22
    • 78649987980 scopus 로고    scopus 로고
    • Repression of E-cadherin by SNAIL, ZEB1, and TWIST in invasive ductal carcinomas of the breast: A cooperative effort?
    • N. Montserrat, A. Gallardo, and D. Escuin Repression of E-cadherin by SNAIL, ZEB1, and TWIST in invasive ductal carcinomas of the breast: a cooperative effort? Hum Pathol 42 2011 103 110
    • (2011) Hum Pathol , vol.42 , pp. 103-110
    • Montserrat, N.1    Gallardo, A.2    Escuin, D.3
  • 23
    • 67650663205 scopus 로고    scopus 로고
    • Changes in the expression of E-cadherin repressors, Snail, Slug, SIP1, and Twist, in the development and progression of ovarian carcinoma: The important role of Snail in ovarian tumorigenesis and progression
    • J. Yoshida, A. Horiuchi, and N. Kikuchi Changes in the expression of E-cadherin repressors, Snail, Slug, SIP1, and Twist, in the development and progression of ovarian carcinoma: the important role of Snail in ovarian tumorigenesis and progression Med Mol Morphol 42 2009 82 91
    • (2009) Med Mol Morphol , vol.42 , pp. 82-91
    • Yoshida, J.1    Horiuchi, A.2    Kikuchi, N.3
  • 24
    • 0141760411 scopus 로고    scopus 로고
    • Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells
    • T. Imai, A. Horiuchi, and C. Wang Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells Am J Pathol 163 2003 1437 1447
    • (2003) Am J Pathol , vol.163 , pp. 1437-1447
    • Imai, T.1    Horiuchi, A.2    Wang, C.3
  • 25
    • 84867404032 scopus 로고    scopus 로고
    • High expression of nuclear Snail, but not cytoplasmic staining, predicts poor survival in nasopharyngeal carcinoma
    • W.R. Luo, S.Y. Li, L.M. Cai, and K.T. Yao High expression of nuclear Snail, but not cytoplasmic staining, predicts poor survival in nasopharyngeal carcinoma Ann Surg Oncol 19 2012 2971 2979
    • (2012) Ann Surg Oncol , vol.19 , pp. 2971-2979
    • Luo, W.R.1    Li, S.Y.2    Cai, L.M.3    Yao, K.T.4
  • 26
    • 84863332428 scopus 로고    scopus 로고
    • Snail is an independent prognostic predictor for progression and patient survival of gastric cancer
    • H. He, W. Chen, and X. Wang Snail is an independent prognostic predictor for progression and patient survival of gastric cancer Cancer Sci 103 2012 1296 1303
    • (2012) Cancer Sci , vol.103 , pp. 1296-1303
    • He, H.1    Chen, W.2    Wang, X.3
  • 27
    • 84865160116 scopus 로고    scopus 로고
    • Transcriptional repressor snail and metastasis in hepatocellular carcinoma
    • D. Chen, X. Zheng, X. Jiao, Y. Gao, K. Zhang, and J. Liang Transcriptional repressor snail and metastasis in hepatocellular carcinoma Hepatogastroenterology 59 2012 1359 1365
    • (2012) Hepatogastroenterology , vol.59 , pp. 1359-1365
    • Chen, D.1    Zheng, X.2    Jiao, X.3    Gao, Y.4    Zhang, K.5    Liang, J.6
  • 28
    • 78650975722 scopus 로고    scopus 로고
    • Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression
    • M.T. Huang, P.L. Wei, and J.J. Liu Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression Ann Surg Oncol 17 2010 3379 3385
    • (2010) Ann Surg Oncol , vol.17 , pp. 3379-3385
    • Huang, M.T.1    Wei, P.L.2    Liu, J.J.3
  • 29
    • 77955270730 scopus 로고    scopus 로고
    • Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) gene, suppresses anchorage-independent cell growth of lung cancer cells
    • Y. Takeyama, M. Sato, and M. Horio Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) gene, suppresses anchorage- independent cell growth of lung cancer cells Cancer Lett 296 2010 216 224
    • (2010) Cancer Lett , vol.296 , pp. 216-224
    • Takeyama, Y.1    Sato, M.2    Horio, M.3
  • 30
    • 33645732687 scopus 로고    scopus 로고
    • The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers
    • N.S. Spoelstra, N.G. Manning, and Y. Higashi The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers Cancer Res 66 2006 3893 3902
    • (2006) Cancer Res , vol.66 , pp. 3893-3902
    • Spoelstra, N.S.1    Manning, N.G.2    Higashi, Y.3
  • 31
    • 68549106083 scopus 로고    scopus 로고
    • E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer
    • O. Schmalhofer, S. Brabletz, and T. Brabletz E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer Cancer Metastasis Rev 28 2009 151 166
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 151-166
    • Schmalhofer, O.1    Brabletz, S.2    Brabletz, T.3
  • 32
    • 77953884067 scopus 로고    scopus 로고
    • Vimentin expression of esophageal squamous cell carcinoma and its aggressive potential for lymph node metastasis
    • H. Jin, S. Morohashi, and F. Sato Vimentin expression of esophageal squamous cell carcinoma and its aggressive potential for lymph node metastasis Biomed Res 31 2010 105 112
    • (2010) Biomed Res , vol.31 , pp. 105-112
    • Jin, H.1    Morohashi, S.2    Sato, F.3
  • 33
    • 70349664021 scopus 로고    scopus 로고
    • Role of protein kinase C in advanced glycation end products-induced epithelial-mesenchymal transition in renal proximal tubular epithelial cells
    • S. Ge, R. Zeng, and Y. Luo Role of protein kinase C in advanced glycation end products-induced epithelial-mesenchymal transition in renal proximal tubular epithelial cells J Huazhong Univ Sci Technolog Med Sci 29 2009 281 285
    • (2009) J Huazhong Univ Sci Technolog Med Sci , vol.29 , pp. 281-285
    • Ge, S.1    Zeng, R.2    Luo, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.