Effects of acute and subchronic AT1 receptor blockade on cardiovascular, hydromineral and neuroendocrine responses in female rats

Physiology and Behavior

Volumn 122, Issue , 2013, Pages 104-112

  Araujo, Iracema Gomes ^a   Elias, Lucila Leico Kagohara ^b   Antunes Rodrigues, José ^b   Reis, Luís Carlos ^a   Mecawi, Andre Souza ^b  

^a FEDERAL RURAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

AT1 receptors; Estrogen; Hypotension; Sodium appetite; Thirst

Indexed keywords

ANGIOTENSIN II; ATRIAL NATRIURETIC FACTOR; ESTRADIOL; LOSARTAN; OXYTOCIN; SODIUM; VASOPRESSIN;

ARTICLE; CARDIOVASCULAR RESPONSE; FEMALE; FLUID INTAKE; HEART RATE; HYPOTENSION; MEAN ARTERIAL PRESSURE; NATRIURESIS; NEUROENDOCRINE SYSTEM; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; SALT INTAKE; SODIUM APPETITE; SODIUM BLOOD LEVEL; WISTAR RAT;

AT1 RECEPTORS; ESTROGEN; HYPOTENSION; SODIUM APPETITE; THIRST;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; ARTERIAL PRESSURE; ATRIAL NATRIURETIC FACTOR; ESTRADIOL; FEMALE; HEART RATE; LOSARTAN; OVARIECTOMY; OXYTOCIN; RATS; RATS, WISTAR; SODIUM; VASOPRESSINS;

EID: 84884408180     PISSN: 00319384     EISSN: 1873507X     Source Type: Journal    
DOI: 10.1016/j.physbeh.2013.08.018     Document Type: Article

References (58)

1. Johnson A.K., Thunhorst R.L. The neuroendocrinology of thirst and salt appetite: visceral sensory signals and mechanisms of central integration. Front Neuroendocrinol 1997, 18:292-353.
2. Antunes-Rodrigues J., de Castro M., Elias L.L., Valença M.M., McCann S.M. Neuroendocrine control of body fluid metabolism. Physiol Rev 2004, 84:169-208.
3. Somponpun S.J. Neuroendocrine regulation of fluid and electrolyte balance by ovarian steroids: contributions from central oestrogen receptors. J Neuroendocrinol 2007, 19:809-818.
4. Mecawi A.S., Lepletier A., Araujo I.G., Olivares E.L., Reis L.C. Assessment of brain AT1-receptor on the nocturnal basal and angiotensin-induced thirst and sodium appetite in ovariectomised rats. J Renin Angiotensin Aldosterone Syst 2007, 8:169-175.
5. Mecawi A.S., Lepletier A., Araujo I.G., Fonseca F.V., Reis L.C. Oestrogenic influence on brain AT1 receptor signalling on the thirst and sodium appetite in osmotically stimulated and sodium-depleted female rats. Exp Physiol 2008, 93:1002-1010.
6. Mecawi A.S., Vilhena-Franco T., Araujo I.G., Reis L.C., Elias L.L., Antunes-Rodrigues J. Estradiol potentiates hypothalamic vasopressin and oxytocin neuron activation and hormonal secretion induced by hypovolemic shock. Am J Physiol Regul Integr Comp Physiol 2011, 301:R905-R915.
7. Curtis K.S. Estrogen and the central control of body fluid balance. Physiol Behav 2009, 97:180-192.
8. Fitzsimons J.T. Angiotensin, thirst, and sodium appetite. Physiol Rev 1998, 78:583-686.
9. Reis L.C. Role of the serotoninergic system in the sodium appetite control. An Acad Bras Cienc 2007, 79:261-283.
10. Ojeda N.B., Intapad S., Royals T.P., Black J.T., Dasinger J.H., Tull F.L., et al. Hypersensitivity to acute ANG II in female growth-restricted offspring is exacerbated by ovariectomy. Am J Physiol Regul Integr Comp Physiol 2011, 301:R1199-R1205.
11. Nickenig G., Bäumer A.T., Grohè C., Kahlert S., Strehlow K., Rosenkranz S., et al. Estrogen modulates AT1 receptor gene expression in vitro and in vivo. Circulation 1998, 97:2197-2201.
12. Kisley L.R., Sakai R.R., Ma L.Y., Fluharty S.J. Estrogen decreases hypothalamic angiotensin II AT1 receptor binding and mRNA in the female rats. Brain Res 1999, 844:34-42.
13. Dean S.A., Tan J., O'Brien E.R., Leenen F.H.H. 17-β-estradiol downregulates tissue angiotensin-converting enzyme ANG II type 1 receptor in female rats. Am J Physiol Regul Integr Comp Physiol 2005, 288:R759-R766.
14. Antunes Rodrigues J., Covian M.R. Hypothalamic control of sodium chloride and water intake. Acta Physiol Lat Am 1963, 13:94-100.
15. Vilhena-Franco T., Mecawi A.S., Elias L.L.K., Antunes-Rodrigues J. Oestradiol potentiates hormone secretion and neuronal activation in response to hypertonic extracellular volume expansion in ovariectomised rats. J Neuroendocrinol 2011, 23:481-489.
16. Ventura R.R., Gomes D.A., Reis W.L., Elias L.L., Castro M., Valença M.M., et al. Nitrergic modulation of vasopressin, oxytocin and atrial natriuretic peptide secretion in response to sodium intake and hypertonic blood volume expansion. Braz J Med Biol Res 2002, 35:1101-1109.
17. Frajewicki V., Kahana L., Yechieli H., Brod V., Kohan R., Bitterman H. Effects of severe hemorrhage on plasma ANP and glomerular ANP receptors. Am J Physiol Regul Integr Comp Physiol 1997, 273:R1623-R1630.
18. Schiltz J.C., Hoffman G.E., Stricker E.M., Sved A.F. Decreases in arterial pressure activate oxytocin neurons in conscious rats. Am J Physiol Regul Integr Comp Physiol 1997, 273:R1474-R1483.
19. Wenner M.M., Stachenfeld N.S. Blood pressure and water regulation: understanding sex hormone effects within and between men and women. J Physiol 2012, 590:5949-5961.
20. Maric-Bilkan C., Manigrasso M.B. Sex differences in hypertension: contribution of the renin-angiotensin system. Gend Med 2012, 9:287-291.
21. Mirza F.S., Ong P., Collins P., Okamura K., Gerhard-Herman M., Williams G.H., et al. Effects of estradiol and the angiotensin II receptor blocker irbesartan on vascular function in postmenopausal women. Menopause 2008, 15:44-50.
22. Graves N.S., Hayes H., Fan L., Curtis K.S. Time course of behavioral, physiological, and morphological changes after estradiol treatment of ovariectomized rats. Physiol Behav 2012, 103(3-4):261-267.
23. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
24. Brown A.J., Casals-Stenzel J., Gofford S., Lever A.F., Morton J.J. Comparison of fast and slow pressor effects of angiotensin II in the conscious rat. Am J Physiol Heart Circ Physiol 1981, 241:H381-H388.
25. Reid I.A. Interactions between ANG II, sympathetic nervous system, and baroreceptor reflexes in regulation of blood pressure. Am J Physiol Endocrinol Metab 1992, 262:E763-E778.
26. Krause E.G., Curtis K.S., Markle J.P., Contreras R.J. Oestrogen affects the cardiovascular and central responses to isoproterenol of female rats. J Physiol 2007, 582:435-447.
27. Giménez J., García M.P., Serna M., Bonacasa B., Carbonell L.F., Quesada T., et al. 17beta-oestradiol enhances the acute hypotensive effect of captopril in female ovariectomized spontaneously hypertensive rats. Exp Physiol 2006, 91:715-722.
28. Saleh T.M., Connell B.J. Role of oestrogen in the central regulation of autonomic function. Clin Exp Pharmacol Physiol 2007, 34:827-832.
29. Spary E.J., Maqbool A., Batten T.F. Oestrogen receptors in the central nervous system and evidence for their role in the control of cardiovascular function. J Chem Neuroanat 2009, 38:185-196.
30. Saleh T.M., Connell B.J. 17beta-estradiol modulates baroreflex sensitivity and autonomic tone of female rats. J Auton Nerv Syst 2000, 80:148-161.
31. Shughrue P.J., Lane M.V., Merchenthaler I. Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system. J Comp Neurol 1997, 388507-388525.
32. Chan R.K., Sawchenko P.E. Spatially and temporally differentiated patterns of c-Fos expression in brainstem catecholaminergic cell groups induced by cardiovascular challenges in the rat. J Comp Neurol 1994, 348:433-460.
33. + transporter redistribution patterns. Am J Physiol Regul Integr Comp Physiol 2004, 287:R878-R885.
34. Peng Y., Knox F.G. Comparison of systemic and direct intrarenal angiotensin II blockade on sodium excretion in rats. Am J Physiol Renal Physiol 1995, 269:F40-F46.
35. Lohmeier T.E., Cowley A.W., Trippodo N.C., Hall J.E., Guyton A.C. Effects of endogenous angiotensin II on renal sodium excretion and renal hemodynamics. Am J Physiol Renal Physiol 1977, 233:F388-F395.
36. DiBona G.F., Esler M. Translational medicine: the antihypertensive effect of renal denervation. Am J Physiol Regul Integr Comp Physiol 2010, 298:R245-R253.
37. Houpt K.A., Epstein A.N. The complete dependence of beta-adrenergic drinking on the renal dipsogen. Physiol Behav 1971, 7:897-902.
38. Krause E.G., Curtis K.S., Davis L.M., Stowe J.R., Contreras R.J. Estrogen influences stimulated water intake by ovariectomized female rats. Physiol Behav 2003, 79(2):267-274.
39. Kisley L.R., Sakai R.R., Ma L.Y., Fluhart S.J. Ovarian steroid regulation of angiotensin II-induced water intake in the rat. Am J Physiol 1999, 276:R90-R96.
40. Thornton S.N., Sanchez A., Nicolaïdis S. An angiotensin-independent, hypotension-induced, sodium appetite in the rat. Physiol Behav 1995, 57:555-561.
41. Collister J.P., Nahey D.B. Changing dietary sodium alters the chronic cardiovascular effects of losartan in rats. J Renin Angiotensin Aldosterone Syst 2008, 9:10-16.
42. Brooks V.L. Chronic infusion of angiotensin II resets baroreflex control of heart rate by an arterial pressure-independent mechanism. Hypertension 1995, 26:420-424.
43. Dalmasso C., Amigone J.L., Vivas L. Serotonergic system involvement in the inhibitory action of estrogen on induced sodium appetite in female rats. Physiol Behav 2011, 104:398-407.
44. Curtis K.S., Contreras R.J. Sex differences in electrophysiological and behavioral responses to NaCl taste. Behav Neurosci 2006, 120:917-924.
45. Schweda F., Friis U., Wagner C., Skott O., Kurtz A. Renin release. Physiology (Bethesda) 2007, 22:310-319.
46. Stricker E.M., Hosutt J.A., Verbalis J.G. Neurohypophyseal secretion in hypovolemic rats: inverse relation to sodium appetite. Am J Physiol Regul Integr Comp Physiol 1987, 252:R889-R896.
47. Shen E., Dun S.L., Ren C., Bennett-Clarke C., Dun N.J. Hypotension preferentially induces c-Fos immunoreactivity in supraoptic vasopressin neurons. Brain Res 1992, 593:136-139.
48. Huang W., Sjöquist M., Skott O., Stricker E.M., Sved A.F. Oxytocin antagonist disrupts hypotension-evoked renin secretion and other responses in conscious rats. Am J Physiol Regul Integr Comp Physiol 2001, 280:R760-R765.
49. Lenkei Z., Palkovits M., Corvol P., Llorens-Cortes C. Distribution of angiotensin type-1 receptor messenger RNA expression in the adult rat brain. Neuroscience 1998, 82:827-841.
50. Sladek C.D., Joynt R.J. Angiotensin stimulation of vasopressin release from the rat hypothalamo-neurohypophyseal system in organ culture. Endocrinology 1979, 104:148-153.
51. Keil L.C., Summy-Long J., Severs W.B. Release of vasopressin by angiotensin II. Endocrinology 1975, 96:1063-1065.
52. Lee W.J., Yang E.K., Ahn D.K., Park Y.Y., Park J.S., Kim H.J. Central ANG II-receptor antagonists impair cardiovascular and vasopressin response to hemorrhage in rats. Am J Physiol Regul Integr Comp Physiol 1995, 268:R1500-R1506.
53. Renaud L.P. CNS pathways mediating cardiovascular regulation of vasopressin. Clin Exp Pharmacol Physiol 1996, 23:157-160.
54. Smith D.W., Day T.A. Catecholamine and oxytocin cells respond to hypovolaemia as well as hypotension. Neuroreport 2003, 14:1493-1495.
55. Yang E.K., Lee W.J., Park Y.Y., Ahn D.K., Park J.S., Kim H.J. Effects of chronic central administration of losartan on the cardiovascular and hormonal responses to hemorrhage in conscious rats. Regul Pept 1996, 67:107-113.
56. Huang W., Sjöquist M., Skott O., Stricker E.M., Sved A.F. Oxytocin-induced renin secretion in conscious rats. Am J Physiol Regul Integr Comp Physiol 2000, 278:R226-R230.
57. Engelmann M., Wotjak C.T., Landgraf R. Differential central and peripheral release of vasopressin and oxytocin in response to swim stress in rats. Adv Exp Med Biol 1998, 449:175-177.
58. Madden C.J., Stocker S.D., Sved A.F. Attenuation of homeostatic responses to hypotension and glucoprivation after destruction of catecholaminergic rostral ventrolateral medulla neurons. Am J Physiol Regul Integr Comp Physiol 2006, 291:R751-R759.