Surface association of pht proteins of streptococcus pneumoniae

Infection and Immunity

Volumn 81, Issue 10, 2013, Pages 3644-3651

  Plumptre, Charles D ^a   Ogunniyi, Abiodun D ^a   Paton, James C ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ARGININE; BACTERIAL PROTEIN; ERYTHROMYCIN; GLUTAMINE; HISTIDINE; MEMBRANE PROTEIN; PHTA PROTEIN; POLYHISTIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOLYSIS; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM CULTURE; CELL ADHESION; CELL SURFACE; CONTROLLED STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PNEUMOCOCCAL INFECTION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; SUPERNATANT; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; BACTERIAL PROTEINS; FITNESS CENTERS; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; MEMBRANE PROTEINS; MICE; PNEUMOCOCCAL INFECTIONS; POINT MUTATION; PROTEIN TRANSPORT; STREPTOCOCCUS PNEUMONIAE; VIRULENCE;

EID: 84884399920     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00562-13     Document Type: Article

References (41)

1. Walker CLF, Rudan I, Liu L, Nair H, Theodoratou E, Bhutta ZA, O'Brien KL, Campbell H, Black RE. 2013. Global burden of childhood pneumonia and diarrhoea. Lancet 381:1405-1416.
2. Jedrzejas MJ. 2007. Unveiling molecular mechanisms of bacterial surface proteins: Streptococcus pneumoniae as a model organism for structural studies. Cell. Mol. Life. Sci. 64:2799-2822.
3. Kadioglu A, Weiser JN, Paton JC, Andrew PW. 2008. The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nat. Rev. Microbiol. 6:288-301.
4. Pérez-Dorado I, Galan-Bartual S, Hermoso JA. 2012. Pneumococcal surface proteins: when the whole is greater than the sum of its parts. Mol. Oral Microbiol. 27:221-245.
5. Paterson GK, Mitchell TJ. 2004. The biology of Gram-positive sortase enzymes. Trends Microbiol. 12:89-95.
6. Nobbs AH, Lamont RJ, Jenkinson HF. 2009. Streptococcus adherence and colonization. Microbiol. Mol. Biol. Rev. 73:407-450.
7. Henderson B, Martin A. 2011. Bacterial virulence in the moonlight: multitasking bacterial moonlighting proteins are virulence determinants in infectious disease. Infect. Immun. 79:3476-3491.
8. Bergmann S. 2006. Versatility of pneumococcal surface proteins. Microbiology 152:295-303.
9. Adamou JE, Heinrichs JH, Erwin AL, Walsh W, Gayle T, Dormitzer M, Dagan R, Brewah YA, Barren P, Lathigra R, Langermann S, Koenig S, Johnson S. 2001. Identification and characterization of a novel family of pneumococcal proteins that are protective against sepsis. Infect. Immun. 69:949-958.
10. Rioux S, Neyt C, Di Paolo E, Turpin L, Charland N, Labbe S, Mortier MC, Mitchell TJ, Feron C, Martin D, Poolman JT. 2011. Transcriptional regulation, occurrence and putative role of the Pht family of Streptococcus pneumoniae. Microbiology 157:336-348.
11. Plumptre CD, Ogunniyi AD, Paton JC. 2012. Polyhistidine triad proteins of pathogenic streptococci. Trends Microbiol. 20:485-493.
12. Ogunniyi AD, Grabowicz M, Mahdi LK, Cook J, Gordon DL, Sadlon TA, Paton JC. 2009. Pneumococcal histidine triad proteins are regulated by the Zn2+-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H. FASEB J. 23:731-738.
13. Melin M, Tikkanen E DIPL, Jarva H, Neyt C, Kayhty H, Meri S, Poolman J, Vakevainen M. 2010. Interaction of pneumococcal histidine triad proteins with human complement. Infect. Immun. 78:2089-2098.
14. Loisel E, Chimalapati S, Bougault C, Imberty A, Gallet B, Di Guilmi AM, Brown J, Vernet T, Durmort C. 2011. Biochemical characterization of the histidine triad protein PhtD as a cell surface zinc-binding protein of pneumococcus. Biochemistry 50:3551-3558.
15. Khan MN, Pichichero ME. 2012. Vaccine candidates PhtD and PhtE of Streptococcus pneumoniae are adhesins that elicit functional antibodies in humans. Vaccine 30:2900-2907.
16. Godfroid F, Hermand P, Verlant V, Denoël P, Poolman JT. 2011. Preclinical evaluation of the Pht proteins as potential cross-protective pneumococcal vaccine antigens. Infect. Immun. 79:238-245.
17. Denoël P, Philipp MT, Doyle L, Martin D, Carletti G, Poolman JT. 2011. A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae. Vaccine 29:5495-5501.
18. Hamel J, Charland N, Pineau I, Ouellet C, Rioux S, Martin D, Brodeur BR. 2004. Prevention of pneumococcal disease in mice immunized with conserved surface-accessible proteins. Infect. Immun. 72:2659-2670.
19. Zhang Y, Masi AW, Barniak V, Mountzouros K, Hostetter MK, Green BA. 2001. Recombinant PhpA protein, a unique histidine motifcontaining protein from Streptococcus pneumoniae, protects mice against intranasal pneumococcal challenge. Infect. Immun. 69:3827-3836.
20. Wizemann TM, Heinrichs JH, Adamou JE, Erwin AL, Kunsch C, Choi GH, Barash SC, Rosen CA, Masure HR, Tuomanen E, Gayle A, Brewah YA, Walsh W, Barren P, Lathigra R, Hanson M, Langermann S, Johnson S, Koenig S. 2001. Use of a whole genome approach to identify vaccine molecules affording protection against Streptococcus pneumoniae infection. Infect. Immun. 69:1593-1598.
21. Choi C-W, Lee YG, Kwon S-O, Kim H-Y, Lee JC, Chung Y-H, Yun C-Y, Kim SI. 2012. Analysis of Streptococcus pneumoniae secreted antigens by immuno-proteomic approach. Diagn. Microbiol. Infect. Dis. 72:318-327.
22. Horton RM, Ho SN, Pullen JK, Hunt HD, Cai Z, Pease LR. 1993. Gene splicing by overlap extension. Methods Enzymol. 217:270-279.
23. McAllister LJ, Tseng HJ, Ogunniyi AD, Jennings MP, McEwan AG, Paton JC. 2004. Molecular analysis of the psa permease complex of Streptococcus pneumoniae. Mol. Microbiol. 53:889-901.
24. Sung CK, Li H, Claverys JP, Morrison DA. 2001. An rpsL cassette, janus, for gene replacement through negative selection in Streptococcus pneumoniae. Appl. Environ. Microbiol. 67:5190-5196.
25. Pearce BJ, Iannelli F, Pozzi G. 2002. Construction of new unencapsulated (rough) strains of Streptococcus pneumoniae. Res. Microbiol. 153: 243-247.
26. Ogunniyi AD, Mahdi LK, Trappetti C, Verhoeven N, Mermans D, Van der Hoek MB, Plumptre CD, Paton JC. 2012. Identification of genes that contribute to pathogenesis of invasive pneumococcal disease by in vivo transcriptomic analysis. Infect. Immun. 80:3268-3278.
27. McAllister LJ, Ogunniyi AD, Stroeher UH, Leach AJ, Paton JC. 2011. Contribution of serotype and genetic background to virulence of serotype 3 and serogroup 11 pneumococcal isolates. Infect. Immun. 79:4839-4849.
28. Juncker AS, Willenbrock H, Von Heijne G, Brunak S, Nielsen H, Krogh A. 2003. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Protein Sci. 12:1652-1662.
29. Petersen TN, Brunak S, Von Heijne G, Nielsen H. 2011. SignalP 4.0: discriminating signal peptides from transmembrane regions. Nat. Methods 8:785-786.
30. Seiberling M, Bologa M, Brookes R, Ochs M, Go K, Neveu D, Kamtchoua T, Lashley P, Yuan T, Gurunathan S. 2012. Safety and immunogenicity of a pneumococcal histidine triad protein D vaccine candidate in adults. Vaccine 30:7455-7460.
31. Kharat AS, Tomasz A. 2003. Inactivation of the srtA gene affects localization of surface proteins and decreases adhesion of Streptococcus pneumoniae to human pharyngeal cells in vitro. Infect. Immun. 71:2758-2765.
32. Price KE, Camilli A. 2009. Pneumolysin localizes to the cell wall of Streptococcus pneumoniae. J. Bacteriol. 191:2163-2168.
33. Price KE, Greene NG, Camilli A. 2012. Export requirements of pneumolysin in Streptococcus pneumoniae. J. Bacteriol. 194:3651-3660.
34. López R, García E. 2004. Recent trends on the molecular biology of pneumococcal capsules, lytic enzymes, and bacteriophage. FEMS Microbiol. Rev. 28:553-580.
35. Hammerschmidt S, WolffS, Hocke A, Rosseau S, Müller E, Rohde M. 2005. Illustration of pneumococcal polysaccharide capsule during adherence and invasion of epithelial cells. Infect. Immun. 73:4653-4667.
36. Weinberger DM, Trzciński K, Lu Y-J, Bogaert D, Brandes A, Galagan J, Anderson PW, Malley R, Lipsitch M. 2009. Pneumococcal capsular polysaccharide structure predicts serotype prevalence. PLoS Pathog. 5:e1000476.
37. Bergmann S, Rohde M, Chhatwal GS, Hammerschmidt S. 2001. Alphaenolase of Streptococcus pneumoniae is a plasmin(ogen)-binding protein displayed on the bacterial cell surface. Mol. Microbiol. 40:1273-1287.
38. Pichichero ME, Kaur R, Casey JR, Xu Q, Almudevar A, Ochs M. 2012. Antibody response to Streptococcus pneumoniae proteins PhtD, LytB, PcpA, PhtE and Ply after nasopharyngeal colonization and acute otitis media in children. Hum. Vaccin. Immunother. 8:799-805.
39. Hagerman A, Posfay-Barbe KM, Grillet S, Ochs MM, Brookes RH, Greenberg D, Givon-Lavi N, Dagan R, SiegristC-A. 2013. Influence of age, social patterns and nasopharyngeal carriage on antibodies to three conserved pneumococcal surface proteins (PhtD, PcpA and PrtA) in healthy young children. Eur. J. Clin. Microbiol. Infect. Dis. 32:43-49.
40. Briles DE, Nahm M, Schroer K, Davie J, Baker P, Kearney J, Barletta R. 1981. Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 Streptococcus pneumoniae. J. Exp. Med. 153:694-705.
41. Trappetti C, Van der Maten E, Amin Z, Potter AJ, Chen AY, Van Mourik PM, Lawrence AJ, Paton AW, Paton JC. 2013. Site of isolation determines biofilm formation and virulence phenotypes of serotype 3 Streptococcus pneumoniae clinical isolates. Infect. Immun. 81:505-513.