Transcriptional regulation, occurrence and putative role of the Pht family of Streptococcus pneumoniae

Microbiology

Volumn 157, Issue 2, 2011, Pages 335-348

  Rioux, Stéphane ^a   Neyt, Cécile ^a   Di Paolo, Emmanuel ^a   Turpin, Laurence ^a   Charland, Nathalie ^b   Labbé, Steve ^c   Mortier, Marie Cécile ^a   Mitchell, Tim J ^d   Feron, Christiane ^a   Martin, Denis ^c   Poolman, Jan T ^a  

^a GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

^b Medicago Inc   (Canada)

^c GSK Biologicals   (Canada)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; MANGANESE; MESSENGER RNA; PNEUMOCOCCUS VACCINE; PROTEIN PHT; SCAVENGER; UNCLASSIFIED DRUG; ZINC ION; BACTERIAL DNA; ZINC;

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; CULTURE MEDIUM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEQUENCE ANALYSIS; STREPTOCOCCUS PNEUMONIAE; TRANSCRIPTION REGULATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR GENETICS; MULTIGENE FAMILY; MUTATION; PROMOTER REGION; REGULATOR GENE;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

BACTERIAL PROTEINS; BASE SEQUENCE; DNA, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; MANGANESE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTATION; PROMOTER REGIONS, GENETIC; STREPTOCOCCUS PNEUMONIAE; TERMINATOR REGIONS, GENETIC; TRANSCRIPTION, GENETIC; ZINC;

EID: 79951476170     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.042184-0     Document Type: Article

References (58)

1. Adamou, J. E., Heinrichs, J. H., Erwin, A. L., Walsh, W., Gayle, T., Dormitzer, M., Dagan, R., Brewah, Y. A., Barren, P. & other authors (2001). Identification and characterization of a novel family of pneumococcal proteins that are protective against sepsis. Infect Immun 69, 949-958. (Pubitemid 32109561)
2. Ajdić, D., McShan, W. M., McLaughlin, R. E., Savic, G., Chang, J., Carson, M. B., Primeaux, C., Tian, R., Kenton, S. & other authors (2002). Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen. Proc Natl Acad Sci U S A 99, 14434-14439.
3. Ancsin, J. B. & Kisilevsky, R. (1996). Laminin interactions important for basement membrane assembly are promoted by zinc and implicate laminin zinc finger-like sequences. J Biol Chem 271, 6845-6851. (Pubitemid 26104119)
4. Bandyopadhyay, K., Karmakar, S., Ghosh, A. & Das, P. K. (2002). High affinity binding between laminin and laminin binding protein of Leishmania is stimulated by zinc and may involve laminin zinc-finger like sequences. Eur J Biochem 269, 1622-1629. (Pubitemid 34304461)
5. Beghetto, E., Gargano, N., Ricci, S., Garufi, G., Peppoloni, S., Montagnani, F., Oggioni, M., Pozzi, G. & Felici, F. (2006). Discovery of novel Streptococcus pneumoniae antigens by screening a whole-genome λ-display library. FEMS Microbiol Lett 262, 14-21. (Pubitemid 44212884)
6. Blom, A. M., Kask, L., Ramesh, B. & Hillarp, A. (2003). Effects of zinc on factor I cofactor activity of C4b-binding protein and factor H. Arch Biochem Biophys 418, 108-118. (Pubitemid 37159377)
7. Brendel, V. & Trifonov, E. N. (1984). A computer algorithm for testing potential prokaryotic terminators. Nucleic Acids Res 12, 4411-4427.
8. Brenot, A., Weston, B. F. & Caparon, M. G. (2007). A PerR-regulated metal transporter (PmtA) is an interface between oxidative stress and metal homeostasis in Streptococcus pyogenes. Mol Microbiol 63, 1185-1196. (Pubitemid 46184521)
9. Bridy-Pappas, A. E., Margolis, M. B., Center, K. J. & Isaacman, D. J. (2005). Streptococcus pneumoniae: description of the pathogen, disease epidemiology, treatment, and prevention. Pharmacotherapy 25, 1193-1212. (Pubitemid 41242579)
10. Bunker, V. W., Hinks, L. J., Lawson, M. S. & Clayton, B. E. (1984). Assessment of zinc and copper status of healthy elderly people using metabolic balance studies and measurement of leucocyte concentrations. Am J Clin Nutr 40, 1096-1102. (Pubitemid 15210590)
11. Claverys, J.-P. (2001). A new family of high-affinity ABC manganese and zinc permeases. Res Microbiol 152, 231-243.
12. Cockayne, A., Hill, P. J., Powell, N. B. L., Bishop, K., Sims, C. & Williams, P. (1998). Molecular cloning of a 32-kilodalton lipoprotein component of a novel iron-regulated Staphylococcus epidermidis ABC transporter. Infect Immun 66, 3767-3774. (Pubitemid 28347835)
13. Dagan, R., Engelhard, D., Piccard, E. & Englehard, D. (1992). Epidemiology of invasive childhood pneumococcal infections in Israel. The Israeli Pediatric Bacteremia and Meningitis Group. JAMA 268, 3328-3332.
14. Dagan, R., Käyhty, H., Wuorimaa, T., Yaich, M., Bailleux, F., Zamir, O. & Eskola, J. (2004). Tolerability and immunogenicity of an eleven valent mixed carrier Streptococcus pneumoniae capsular polysaccharide-diphtheria toxoid or tetanus protein conjugate vaccine in Finnish and Israeli infants. Pediatr Infect Dis J 23, 91-98. (Pubitemid 38222778)
15. Dintilhac, A. & Claverys, J.-P. (1997). The adc locus, which affects competence for genetic transformation in Streptococcus pneumoniae, encodes an ABC transporter with a putative lipoprotein homologous to a family of streptococcal adhesins. Res Microbiol 148, 119-131. (Pubitemid 27106905)
16. Dintilhac, A., Alloing, G., Granadel, C. & Claverys, J.-P. (1997). Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases. Mol Microbiol 25, 727-739. (Pubitemid 27394570)
17. Elsner, A., Kreikemeyer, B., Braun-Kiewnick, A., Spellerberg, B., Buttaro, B. A. & Podbielski, A. (2002). Involvement of Lsp, a member of the LraI-lipoprotein family in Streptococcus pyogenes, in eukaryotic cell adhesion and internalization. Infect Immun 70, 4859-4869.
18. Fedson, D. C. & Musher, D. M. (2004). Pneumococcal polysaccharide vaccines. In Vaccines, 4th edn, pp. 529-588. Edited by S. A. Plotkin & W. A. Orenstein. Philadelphia, PA: Elsevier, Inc.
19. Ferretti, J. J., McShan, W. M., Ajdić, D., Savic, D. J., Savic, G., Lyon, K., Primeaux, C., Sezate, S., Suvorov, A. N. & other authors (2001). Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc Natl Acad Sci U S A 98, 4658-4663. (Pubitemid 32295032)
20. Gagnon, G., Vadeboncoeur, C., Levesque, R. C. & Frenette, M. (1992). Cloning, sequencing and expression in Escherichia coli of the ptsI gene encoding enzyme I of the phosphoenolpyruvate:sugar phosphotransferase transport system from Streptococcus salivarius. Gene 121, 71-78.
21. Godfroid, F., Hermand, P., Verlant, V., Denoël, P. & Poolman, J. T. (2011). Preclinical evaluation of the Pht proteins as potential cross-protective pneumococcal vaccine antigens. Infect Immun 79, 238-245.
22. Hamel, J., Charland, N., Pineau, I., Ouellet, C., Rioux, S., Martin, D. & Brodeur, B. R. (2004). Prevention of pneumococcal disease in mice immunized with conserved surface-accessible proteins. Infect Immun 72, 2659-2670. (Pubitemid 38542392)
23. Hanahan, D. (1985). Plasmid transformation by Simanis. In DNA Cloning, pp. 109-135. Edited by D. M. Glover. London: IRL Press.
24. Harlyk, C., Mccourt, J., Bordin, G., Rodriguez, A. R. & van der Eeckhout, A. (1997). Determination of copper, zinc and iron in broncho-alveolar lavages by atomic absorption spectroscopy. J Trace Elem Med Biol 11, 137-142. (Pubitemid 27523797)
25. Hausdorff, W. P., Feikin, D. R. & Klugman, K. P. (2005). Epidemiological differences among pneumococcal serotypes. Lancet Infect Dis 5, 83-93. (Pubitemid 40174779)
26. Hava, D. L. & Camilli, A. (2002). Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Mol Microbiol 45, 1389-1406.
27. Hoskins, J., Alborn, W. E., Jr, Arnold, J., Blaszczak, L. C., Burgett, S., DeHoff, B. S., Estrem, S. T., Fritz, L., Fu, D.-J. & other authors (2001). Genome of the bacterium Streptococcus pneumoniae strain R6. J Bacteriol 183, 5709-5717.
28. Hostetter, M. K. (1999). Opsonic and nonopsonic interactions of C3 with Streptococcus pneumoniae. Microb Drug Resist 5, 85-89.
29. Jenkinson, H. F. (1994). Cell surface protein receptors in oral streptococci. FEMS Microbiol Lett 121, 133-140.
30. Kunst, F., Ogasawara, N., Moszer, I., Albertini, A. M., Alloni, G., Azevedo, V., Bertero, M. G., Bessieres, P., Bolotin, A. & other authors (1997). The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature 390, 249-256. (Pubitemid 27513299)
31. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
32. -ΔΔCT method. Methods 25, 402-408.
33. Loisel, E., Jacquamet, L., Serre, L., Bauvois, C., Ferrer, J. L., Vernet, T., Di Guilmi, A. M. & Durmort, C. (2008). AdcAII, a new pneumococcal Zn-binding protein homologous with ABC transporters: biochemical and structural analysis. J Mol Biol 381, 594-606.
34. Lynch, J. P., III & Zhanel, G. G. (2005). Escalation of antimicrobial resistance among Streptococcus pneumoniae: implications for therapy. Semin Respir Crit Care Med 26, 575-616.
35. Maruvada, R., Prasadarao, N. V. & Rubens, C. E. (2009). Acquisition of factor H by a novel surface protein on group B Streptococcus promotes complement degradation. FASEB J 23, 3967-3977.
36. Mbelle, N., Huebner, R. E., Wasas, A. D., Kimura, A., Chang, I. & Klugman, K. P. (1999). Immunogenicity and impact on nasopharyngeal carriage of a nonavalent pneumococcal conjugate vaccine. J Infect Dis 180, 1171-1176. (Pubitemid 30070201)
37. McCullers, J. A. & Tuomanen, E. I. (2001). Molecular pathogenesis of pneumococcal pneumonia. Front Biosci 6, D877-D889.
38. Melin, M., Di Paolo, E., Tikkanen, L., Jarva, H., Neyt, C., Kayhty, H., Meri, S., Poolman, J. & Vakevainen, M. (2010). Interaction of pneumococcal histidine triad proteins with human complement. Infect Immun 78, 2089-2098.
39. Morrison, D. A. & Jaurin, B. (1990). Streptococcus pneumoniae possesses canonical Escherichia coli (sigma 70) promoters. Mol Microbiol 4, 1143-1152.
40. Nunes, S., Sá-Leão, R., Pereira, L. C. & de Lencastre, H. (2008). Emergence of a serotype 1 Streptococcus pneumoniae lineage colonising healthy children in Portugal in the seven-valent conjugate vaccination era. Clin Microbiol Infect 14, 82-84. (Pubitemid 350226575)
41. Ogunniyi, A. D., Grabowicz, M., Briles, D. E., Cook, J. & Paton, J. C. (2007). Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae. Infect Immun 75, 350-357. (Pubitemid 46047911)
42. 2+-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H. FASEB J 23, 731-738.
43. Panina, E. M., Mironov, A. A. & Gelfand, M. S. (2003). Comparative genomics of bacterial zinc regulons: enhanced ion transport, pathogenesis, and rearrangement of ribosomal proteins. Proc Natl Acad Sci U S A 100, 9912-9917. (Pubitemid 37087042)
44. Papp-Wallace, K. M. & Maguire, M. E. (2006). Manganese transport and the role of manganese in virulence. Annu Rev Microbiol 60, 187-209. (Pubitemid 44627946)
45. Peterson, J. D., Umayam, L. A., Dickinson, T., Hickey, E. K. & White, O. (2001). The comprehensive microbial resource. Nucleic Acids Res 29, 123-125. (Pubitemid 32054424)
46. Ranasinghe, C. & Hobbs, A. A. (1998). A simple method to obtain the 59 ends of mRNA sequences by direct ligation of cDNA-RNA hybrids to a plasmid vector. Tech Tips Online 3, 128-132.
47. Riboldi-Tunnicliffe, A., Isaacs, N. W. & Mitchell, T. J. (2005). 1.2 Å crystal structure of the S. pneumoniae PhtA histidine triad domain a novel zinc binding fold. FEBS Lett 579, 5353-5360. (Pubitemid 41398144)
48. Rosenberg, M. & Court, D. (1979). Regulatory sequences involved in the promotion and termination of RNA transcription. Annu Rev Genet 13, 319-353.
49. Sicard, A. M. (1964). A new synthetic medium for Diplococcus pneumoniae, and its use for the study of reciprocal transformations at the amiA locus. Genetics 50, 31-44.
50. Singleton, R. J., Hennessy, T. W., Bulkow, L. R., Hammitt, L. L., Zulz, T., Hurlburt, D. A., Butler, J. C., Rudolph, K. & Parkinson, A. (2007). Invasive pneumococcal disease caused by nonvaccine serotypes among Alaska native children with high levels of 7-valent pneumococcal conjugate vaccine coverage. JAMA 297, 1784-1792. (Pubitemid 46658647)
51. Smart, L. E., Dougall, A. J. & Girdwood, R. W. A. (1987). New 23-valent pneumococcal vaccine in relation to pneumococcal serotypes in systemic and non-systemic disease. J Infect 14, 209-215. (Pubitemid 17070107)
52. Spellerberg, B., Rozdzinski, E., Martin, S., Weber-Heynemann, J., Schnitzler, N., Lütticken, R. & Podbielski, A. (1999). Lmb, a protein with similarities to the LraI adhesin family, mediates attachment of Streptococcus agalactiae to human laminin. Infect Immun 67, 871-878. (Pubitemid 29059230)
53. Tettelin, H., Nelson, K. E., Paulsen, I. T., Eisen, J. A., Read, T. D., Peterson, S., Heidelberg, J., DeBoy, R. T., Haft, D. H. & other authors (2001). Complete genome sequence of a virulent isolate of Streptococcus pneumoniae. Science 293, 498-506. (Pubitemid 32679078)
54. Towbin, H., Staehelin, T. & Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 76, 4350-4354. (Pubitemid 9256559)
55. Turner, D. H., Sugimoto, N. & Freier, S. M. (1988). RNA structure prediction. Annu Rev Biophys Biophys Chem 17, 167-192.
56. Wizemann, T. M., Heinrichs, J. H., Adamou, J. E., Erwin, A. L., Kunsch, C., Choi, G. H., Barash, S. C., Rosen, C. A., Masure, H. R. & other authors (2001). Use of a whole genome approach to identify vaccine molecules affording protection against Streptococcus pneumoniae infection. Infect Immun 69, 1593-1598. (Pubitemid 32187614)
57. Yamamoto, H., Uchiyama, S., Nugroho, F. A. & Sekiguchi, J. (1997). A 23.4 kb segment at the 69°-70° region of the Bacillus subtilis genome. Microbiology 143, 1317-1320. (Pubitemid 27207800)
58. Zhang, Y., Masi, A. W., Barniak, V., Mountzouros, K., Hostetter, M. K. & Green, B. A. (2001). Recombinant PhpA protein, a unique histidine motif-containing protein from Streptococcus pneumoniae, protects mice against intranasal pneumococcal challenge. Infect Immun 69, 3827-3836. (Pubitemid 32493302)