Safety and pharmacokinetics of sodium nitrite in patients with subarachnoid hemorrhage: A Phase IIA study

Journal of Neurosurgery

Volumn 119, Issue 3, 2013, Pages 634-641

  Oldfield, Edward H ^a   Loomba, Johanna J ^a   Monteith, Stephen J ^a   Crowley, R Webster ^a   Medel, Ricky ^a   Gress, Daryl R ^a   Kassell, Neal F ^a   Dumont, Aaron S ^a   Sherman, Craig ^b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b Hope Pharmaceuticals   (United States)

Author keywords

Nitric oxide; Sodium nitrite; Subarachnoid hemorrhage; Vascular disorders; Vasospasm

Indexed keywords

METHEMOGLOBIN; SODIUM CHLORIDE; SODIUM NITRITE;

ADULT; AGED; ANEMIA; ARTICLE; BLOOD CELL COUNT; BLOOD CHEMISTRY; BLOOD PRESSURE; BODY TEMPERATURE; BREATHING RATE; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DRUG DOSE ESCALATION; DRUG HALF LIFE; DRUG SAFETY; FEVER; HUMAN; HYPONATREMIA; HYPOTENSION; LABORATORY TEST; MASS SPECTROMETRY; PHASE 2 CLINICAL TRIAL; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PULSE OXIMETER; PULSE RATE; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SUBARACHNOID HEMORRHAGE; SYSTOLIC BLOOD PRESSURE; URINALYSIS;

ADULT; AGED; ANEURYSM, RUPTURED; CRITICAL ILLNESS; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; INDICATORS AND REAGENTS; INFUSIONS, INTRAVENOUS; INTRACRANIAL ANEURYSM; MALE; MIDDLE AGED; SODIUM NITRITE; SUBARACHNOID HEMORRHAGE;

EID: 84884397227     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2013.3.JNS13266     Document Type: Article

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