Reversal of cerebral vasospasm via intravenous sodium nitrite after subarachnoid hemorrhage in primates: Laboratory investigation

Journal of Neurosurgery

Volumn 115, Issue 6, 2011, Pages 1213-1220

  Fathi, Ali Reza ^a,b   Pluta, Ryszard M ^a   Bakhtian, Kamran D ^a   Qi, Meng ^a,c   Lonser, Russell R ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b CANTONAL HOSPITAL AARAU   (Switzerland)

^c NANJING UNIVERSITY   (China)

Author keywords

Nitric oxide; Sodium nitrite; Subarachnoid hemorrhage; Traumatic brain injury; Vasospasm

Indexed keywords

NITRATE; NITRITE; S NITROSOTHIOL; SODIUM NITRITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOGRAPHY; ARTICLE; BRAIN ANGIOGRAPHY; BRAIN VASOSPASM; CEREBROSPINAL FLUID; CONTROLLED STUDY; DISEASE SEVERITY; DRUG BLOOD LEVEL; MACACA; METABOLOME; NONHUMAN; PRIORITY JOURNAL; SUBARACHNOID HEMORRHAGE;

ANIMALS; CEREBRAL ANGIOGRAPHY; DISEASE MODELS, ANIMAL; INFUSIONS, INTRAVENOUS; MACACA FASCICULARIS; MIDDLE CEREBRAL ARTERY; NITRATES; NITRIC OXIDE; NITRITES; S-NITROSOTHIOLS; SODIUM NITRITE; SUBARACHNOID HEMORRHAGE; TREATMENT OUTCOME; VASOSPASM, INTRACRANIAL;

EID: 83055172318     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2011.7.JNS11390     Document Type: Article

References (32)

1. Aaslid R, Huber P, Nornes H: Evaluation of cerebrovascular spasm with transcranial Doppler ultrasound. J Neurosurg 60:37-41, 1984 (Pubitemid 14181553)
2. Cosby K, Partovi KS, Crawford JH, Patel RP, Reiter CD, Martyr S, et al.: Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nat Med 9:1498-1505, 2003 (Pubitemid 38004777)
3. Cross DT III, Moran CJ, Angtuaco EE, Milburn JM, Diringer MN, Dacey RG Jr: Intracranial pressure monitoring during intraarterial papaverine infusion for cerebral vasospasm. AJNR Am J Neuroradiol 19:1319-1323, 1998 (Pubitemid 30418681)
4. Crowley RW, Medel R, Dumont AS, Ilodigwe D, Kassell NF, Mayer SA, et al.: Angiographic vasospasm is strongly correlated with cerebral infarction after subarachnoid hemorrhage. Stroke 42:919-923, 2011
5. Dejam A, Hunter CJ, Tremonti C, Pluta RM, Hon YY, Grimes G, et al.: Nitrite infusion in humans and nonhuman primates: endocrine effects, pharmacokinetics, and tolerance formation. Circulation 116:1821-1831, 2007 (Pubitemid 350287107)
6. Doyle MP, Pickering RA, DeWeert TM, Hoekstra JW, Pater D: Kinetics and mechanism of the oxidation of human deoxyhemoglobin by nitrites. J Biol Chem 256:12393-12398, 1981 (Pubitemid 12141507)
7. Espinosa F, Weir B, Overton T, Castor W, Grace M, Boisvert D: A randomized placebo-controlled double-blind trial of nimodipine after SAH in monkeys. Part 1: clinical and radiological findings. J Neurosurg 60:1167-1175, 1984 (Pubitemid 14108236)
8. Frontera JA, Fernandez A, Schmidt JM, Claassen J, Wartenberg KE, Badjatia N, et al.: Clinical response to hypertensive hypervolemic therapy and outcome after subarachnoid hemorrhage. Neurosurgery 66:35-41, 2010
9. Giller CA, Hatab MR, Giller AM: Estimation of vessel flow and diameter during cerebral vasospasm using transcranial Doppler indices. Neurosurgery 42:1076-1082, 1998 (Pubitemid 28196520)
10. Hoh BL, Ogilvy CS: Endovascular treatment of cerebral vasospasm: transluminal balloon angioplasty, intra-arterial papaverine, and intra-arterial nicardipine. Neurosurg Clin N Am 16:501-516, vi, 2005
11. Jung CS, Iuliano BA, Harvey-White J, Espey MG, Oldfield EH, Pluta RM: Association between cerebrospinal fluid levels of asymmetric dimethyl-L-arginine, an endogenous inhibitor of endothelial nitric oxide synthase, and cerebral vasospasm in a primate model of subarachnoid hemorrhage. J Neurosurg 101:836-842, 2004 (Pubitemid 39430979)
12. Jung CS, Oldfield EH, Harvey-White J, Espey MG, Zimmermann M, Seifert V, et al.: Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg 107:945-950, 2007 (Pubitemid 350255207)
13. Kassell NF, Torner JC: The International Cooperative Study on Timing of Aneurysm Surgery - an update. Stroke 15:566-570, 1984 (Pubitemid 14105977)
14. Keefer LK: Progress toward clinical application of the nitric oxide-releasing diazeniumdiolates. Annu Rev Pharmacol Toxicol 43:585-607, 2003
15. MacArthur PH, Shiva S, Gladwin MT: Measurement of circulating nitrite and S-nitrosothiols by reductive chemiluminescence. J Chromatogr B Analyt Technol Biomed Life Sci 851:93-105, 2007 (Pubitemid 46720142)
16. Macdonald RL, Kassell NF, Mayer S, Ruefenacht D, Schmiedek P, Weidauer S, et al.: Clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (CONSCIOUS-1): randomized, double-blind, placebocontrolled phase 2 dose-finding trial. Stroke 39:3015-3021, 2008
17. Macdonald RL, Weir BK: A review of hemoglobin and the pathogenesis of cerebral vasospasm. Stroke 22:971-982, 1991
18. Park KW, Dai HB, Metais C, Comunale ME, Sellke FW: Isoflurane does not further impair microvascular vasomotion in a rat model of subarachnoid hemorrhage. Can J Anaesth 49:427-433, 2002 (Pubitemid 34546177)
19. Pluta RM, Dejam A, Grimes G, Gladwin MT, Oldfield EH: Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage. JAMA 293:1477-1484, 2005 (Pubitemid 40393292)
20. Pluta RM, Oldfield EH, Bakhtian KD, Fathi AR, Smith RK, Devroom HL, et al.: Safety and feasibility of long-term intravenous sodium nitrite infusion in healthy volunteers. PLoS ONE 6:e14504, 2011
21. Pluta RM, Thompson BG, Dawson TM, Snyder SH, Boock RJ, Oldfield EH: Loss of nitric oxide synthase immunoreactivity in cerebral vasospasm. J Neurosurg 84:648-654, 1996 (Pubitemid 26104234)
22. Polin RS, Coenen VA, Hansen CA, Shin P, Baskaya MK, Nanda A, et al.: Efficacy of transluminal angioplasty for the management of symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage. J Neurosurg 92:284-290, 2000 (Pubitemid 30071048)
23. Polin RS, Hansen CA, German P, Chadduck JB, Kassell NF: Intra-arterially administered papaverine for the treatment of symptomatic cerebral vasospasm. Neurosurgery 42:1256-1267, 1998 (Pubitemid 28264858)
24. Raabe A, Zimmermann M, Setzer M, Vatter H, Berkefeld J, Seifert V: Effect of intraventricular sodium nitroprusside on cerebral hemodynamics and oxygenation in poor-grade aneurysm patients with severe, medically refractory vasospasm. Neurosurgery 50:1006-1014, 2002 (Pubitemid 36331136)
25. Reinert M, Wiest R, Barth L, Andres R, Ozdoba C, Seiler R: Transdermal nitroglycerin in patients with subarachnoid hemorrhage. Neurol Res 26:435-439, 2004 (Pubitemid 38758469)
26. Rejdak K, Petzold A, Sharpe MA, Kay AD, Kerr M, Keir G, et al.: Cerebrospinal fluid nitrite/nitrate correlated with oxyhemoglobin and outcome in patients with subarachnoid hemorrhage. J Neurol Sci 219:71-76, 2004 (Pubitemid 38406000)
27. Thomas JE, Rosenwasser RH, Armonda RA, Harrop J, Mitchell W, Galaria I: Safety of intrathecal sodium nitroprusside for the treatment and prevention of refractory cerebral vasospasm and ischemia in humans. Stroke 30:1409-1416, 1999 (Pubitemid 29296069)
28. Tierney TS, Pradilla G, Wang PP, Clatterbuck RE, Tamargo RJ: Intracranial delivery of the nitric oxide donor diethylenetriamine/ nitric oxide from a controlled-release polymer: toxicity in cynomolgus monkeys. Neurosurgery 58:952-960, 2006 (Pubitemid 43772440)
29. Vajkoczy P, Horn P, Bauhuf C, Munch E, Hubner U, Ing D, et al.: Effect of intra-arterial papaverine on regional cerebral blood flow in hemodynamically relevant cerebral vasospasm. Stroke 32:498-505, 2001 (Pubitemid 32155242)
30. Vellimana AK, Milner E, Azad TD, Harries MD, Zhou ML, Gidday JM, et al.: Endothelial nitric oxide synthase mediates endogenous protection against subarachnoid hemorrhage-induced cerebral vasospasm. Stroke 42:776-782, 2011
31. Weir B, Grace M, Hansen J, Rothberg C: Time course of vasospasm in man. J Neurosurg 48:173-178, 1978 (Pubitemid 8269962)
32. Zwienenberg-Lee M, Hartman J, Rudisill N, Madden LK, Smith K, Eskridge J, et al.: Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical trial. Stroke 39:1759-1765, 2008