The role of vitamin D in improving physical performance in the elderly

Journal of Bone and Mineral Research

Volumn 28, Issue 10, 2013, Pages 2194-2201

  Lagari, Violet ^a,b   Gõmez Marín, Orlando ^a   Levis, Silvina ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

body composition; muscle strength; vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; COLECALCIFEROL;

AGED; ARTICLE; BODY COMPOSITION; BODY EQUILIBRIUM; COMPLIANCE (PHYSICAL); CONTROLLED STUDY; FEMALE; GAIT; GERIATRIC NUTRITION; HAND GRIP; HUMAN; MAJOR CLINICAL STUDY; MALE; MUSCLE STRENGTH; PHYSICAL PERFORMANCE; RANDOMIZED CONTROLLED TRIAL; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION; WEIGHT GAIN;

BODY COMPOSITION; MUSCLE STRENGTH; VITAMIN D;

AGED; AGED, 80 AND OVER; BODY COMPOSITION; DEMOGRAPHY; DIETARY SUPPLEMENTS; FEMALE; HUMANS; MALE; MOTOR ACTIVITY; PATIENT COMPLIANCE; PHYSICAL FITNESS; VITAMIN D;

EID: 84884350219     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1949     Document Type: Article

References (50)

1. Cherniack EP, Florez HJ, Hollis BW, Roos BA, Troen BR, Levis S., The response of elderly veterans to daily vitamin D3 supplementation of 2,000 IU: a pilot efficacy study. J Am Geriatr Soc. 2011; 59 (2): 286-90.
2. Shea MK, Houston DK, Tooze JA, Davis CC, Johnson MA, Hausman DB, Cauley JA, Bauer DC, Tylavsky F, Harris TB, Kritchevsky SB., Correlates and prevalence of insufficient 25-hydroxyvitamin D status in black and white older adults: the health, aging and body composition study. J Am Geriatr Soc. 2011; 59 (7): 1165-74.
3. Wicherts IS, van Schoor NM, Boeke AJ, Visser M, Deeg DJ, Smit J, Knol DL, Lips P., Vitamin D status predicts physical performance and its decline in older persons. J Clin Endocrinol Metab. 2007; 92 (6): 2058-65.
4. Wei MY, Giovannucci EL., Vitamin D and multiple health outcomes in the Harvard cohorts. Mol Nutr Food Res. 2010; 54 (8): 1114-26.
5. Dobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Maerz W., Independent association of low serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels with all-cause and cardiovascular mortality. Arch Int Med. 2008; 168 (12): 1340-9.
6. Michaelsson K, Baron JA, Snellman G, Gedeborg R, Byberg L, Sundstrom J, Berglund L, Arnlov J, Hellman P, Blomhoff R, Wolk A, Garmo H, Holmberg L, Melhus H., Plasma vitamin D and mortality in older men: a community-based prospective cohort study. Am J Clin Nutr. 2010; 92 (4): 841-8.
7. Bischoff-Ferrari HA, Willett WC, Wong JB, Stuck AE, Staehelin HB, Orav EJ, Thoma A, Kiel DP, Henschkowski J., Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials. Arch Int Med. 2009; 169 (6): 551-61.
8. Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, Orav JE, Stuck AE, Theiler R, Wong JB, Egli A, Kiel DP, Henschkowski J., Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. BMJ. 2009; 339: b3692.
9. Bischoff-Ferrari HA, Conzelmann M, Stahelin HB, Dick W, Carpenter MG, Adkin AL, Theiler R, Pfeifer M, Allum JH., Is fall prevention by vitamin D mediated by a change in postural or dynamic balance?. Osteoporos Int. 2006; 17 (5): 656-3.
10. Latham NK, Anderson CS, Lee A, Bennett DA, Moseley A, Cameron ID., A randomized, controlled trial of quadriceps resistance exercise and vitamin D in frail older people: the Frailty Interventions Trial in Elderly Subjects (FITNESS). J Am Geriatr Soc. 2003; 51 (3): 291-9.
11. Sato Y, Iwamoto J, Kanoko T, Satoh K., Low-dose vitamin D prevents muscular atrophy and reduces falls and hip fractures in women after stroke: a randomized controlled trial. Cerebrovasc Dis. 2005; 20 (3): 187-92.
12. Bunout D, Barrera G, Leiva L, Gattas V, de la Maza MP, Avendano M, Hirsch S., Effects of vitamin D supplementation and exercise training on physical performance in Chilean vitamin D deficient elderly subjects. Exper Gerontol. 2006; 41 (8): 746-52.
13. Bischoff-Ferrari HA, Dietrich T, Orav EJ, Hu FB, Zhang Y, Karlson EW, Dawson-Hughes B., Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or = 60 y. Am J Clin Nutr. 2004; 80 (3): 752-8.
14. Boxer RS, Dauser DA, Walsh SJ, Hager WD, Kenny AM., The association between vitamin D and inflammation with the 6-minute walk and frailty in patients with heart failure. J Am Geriatr Soc. 2008; 56 (3): 454-61.
15. Houston DK, Cesari M, Ferrucci L, Cherubini A, Maggio D, Bartali B, Johnson MA, Schwartz GG, Kritchevsky SB., Association between vitamin D status and physical performance: the InCHIANTI study. J Gerontol A Biol Sci Med Sci. 2007; 62 (4): 440-6.
16. Kwon J, Suzuki T, Yoshida H, Kim H, Yoshida Y, Iwasa H., Concomitant lower serum albumin and vitamin D levels are associated with decreased objective physical performance among Japanese community-dwelling elderly. Gerontology. 2007; 53 (5): 322-8.
17. Toffanello ED, Perissinotto E, Sergi G, Zambon S, Musacchio E, Maggi S, Coin A, Sartori L, Corti MC, Baggio G, Crepaldi G, Manzato E., Vitamin D and physical performance in elderly subjects: the Pro.V.A. study. PloS One. 2012; 7 (4): e34950.
18. Chan R, Chan D, Woo J, Ohlsson C, Mellstrom D, Kwok T, Leung PC., Not all elderly people benefit from vitamin D supplementation with respect to physical function: results from the Osteoporotic Fractures in Men Study. Hong Kong. J Am Geriatr Soc. 2012; 60 (2): 290-5.
19. Ceglia L, Chiu GR, Harris SS, Araujo AB., Serum 25-hydroxyvitamin D concentration and physical function in adult men. Clin Endocrinol. 2011; 74 (3): 370-6.
20. Michael YL, Smit E, Seguin R, Curb JD, Phillips LS, Manson JE., Serum 25-hydroxyvitamin D and physical performance in postmenopausal women. J Womens Health (Larchmt). 2011; 20 (11): 1603-8.
21. Houston DK, Neiberg RH, Tooze JA, Hausman DB, Johnson MA, Cauley JA, Bauer DC, Shea MK, Schwartz GG, Williamson JD, Harris TB, Kritchevsky SB., Low 25-hydroxyvitamin D predicts the onset of mobility limitation and disability in community-dwelling older adults: the Health ABC Study. J Gerontol A Biol Sci Med Sci. 2013; 68 (2): 181-7.
22. Latham NK, Anderson CS, Reid IR., Effects of vitamin D supplementation on strength, physical performance, and falls in older persons: a systematic review. J Am Geriatr Soc. 2003; 51 (9): 1219-26.
23. Dhesi JK, Jackson SH, Bearne LM, Moniz C, Hurley MV, Swift CG, Allain TJ., Vitamin D supplementation improves neuromuscular function in older people who fall. Age Ageing. 2004; 33 (6): 589-95.
24. Gallagher JC, Rapuri PB, Smith LM., An age-related decrease in creatinine clearance is associated with an increase in number of falls in untreated women but not in women receiving calcitriol treatment. J Clin Endocrinol Metab. 2007; 92 (1): 51-8.
25. Mowe M, Haug E, Bohmer T., Low serum calcidiol concentration in older adults with reduced muscular function. J Am Geriatr Soc. 1999; 47 (2): 220-6.
26. Bischoff HA, Stahelin HB, Urscheler N, Ehrsam R, Vonthein R, Perrig-Chiello P, Tyndall A, Theiler R., Muscle strength in the elderly: its relation to vitamin D metabolites. Arch Phys Med Rehabil. 1999; 80 (1): 54-8.
27. Zamboni M, Zoico E, Tosoni P, Zivelonghi A, Bortolani A, Maggi S, Di Francesco V, Bosello O., Relation between vitamin D, physical performance, and disability in elderly persons. J Gerontol A Biol Sci Med Sci. 2002; 57 (1): M7-11.
28. Dhesi JK, Bearne LM, Moniz C, Hurley MV, Jackson SH, Swift CG, Allain TJ., Neuromuscular and psychomotor function in elderly subjects who fall and the relationship with vitamin D status. J Bone Miner Res. 2002; 17 (5): 891-7.
29. Greenspan SL, Resnick NM, Parker RA., Vitamin D supplementation in older women. J Gerontol A Biol Sci Med Sci. 2005; 60 (6): 754-9.
30. Scott D, Blizzard L, Fell J, Ding C, Winzenberg T, Jones G., A prospective study of the associations between 25-hydroxy-vitamin D, sarcopenia progression and physical activity in older adults. Clin Endocrinol. 2010; 73 (5): 581-7.
31. Faulkner KA, Cauley JA, Zmuda JM, Landsittel DP, Newman AB, Studenski SA, Redfern MS, Ensrud KE, Fink HA, Lane NE, Nevitt MC., Higher 1,25-dihydroxyvitamin D3 concentrations associated with lower fall rates in older community-dwelling women. Osteoporos Int. 2006; 17 (9): 1318-28.
32. Gerdhem P, Ringsberg KA, Obrant KJ, Akesson K., Association between 25-hydroxy vitamin D levels, physical activity, muscle strength and fractures in the prospective population-based OPRA Study of Elderly Women. Osteoporos Int. 2005; 16 (11): 1425-31.
33. Imms FJ, Edholm OG., Studies of gait and mobility in the elderly. Age Ageing. 1981; 10 (3): 147-56.
34. Csuka M, McCarty DJ., Simple method for measurement of lower extremity muscle strength. Am J Med. 1985; 78 (1): 77-81.
35. Briggs RC, Gossman MR, Birch R, Drews JE, Shaddeau SA., Balance performance among noninstitutionalized elderly women. Phys Ther. 1989; 69 (9): 748-56.
36. Anemaet W, Moffa-Trotter M., Functional tools for assessing balance and gait impairments. Top Geriatr Rehab. 1999; 15 (1): 66-83.
37. Lagari VS, Gomez-Marin O, Levis S., Differences in Vitamin D3 dosing regimens in a geriatric community-dwelling population. Endocr Pract. 2012; 1-22.
38. Signorile JF, Sandler D, Ma F, Bamel S, Stanziano D, Smith W, Sandals L, Roos BA., The gallon-jug shelf-transfer test: an instrument to evaluate deteriorating function in older adults. J Aging Phys Act. 2007; 15 (1): 56-74.
39. Heymsfield SB, Smith R, Aulet M, Bensen B, Lichtman S, Wang J, Pierson RN, Jr., Appendicular skeletal muscle mass: measurement by dual-photon absorptiometry. Am J Clin Nutr. 1990; 52 (2): 214-8.
40. Kelly TL, Wilson KE, Heymsfield SB., Dual energy X-ray absorptiometry body composition reference values from NHANES. PloS One. 2009; 4 (9): e7038.
41. Kleinbaum D, Kupper L, Morgenstern H., Confounding. In:, Kleinbaum D, Kupper L, Morgenstern H, editors. Epidemiologic research: principles and quantitative methods. Belmont. CA: Lifetime Learning Publications; p. 242-65. 1982.
42. Schott GD, Wills MR., Muscle weakness in osteomalacia. Lancet. 1976; 1 (7960): 626-9.
43. Bischoff HA, Stahelin HB, Dick W, Akos R, Knecht M, Salis C, Nebiker M, Theiler R, Pfeifer M, Begerow B, Lew RA, Conzelmann M., Effects of vitamin D and calcium supplementation on falls: a randomized controlled trial. J Bone Miner Res. 2003; 18 (2): 343-51.
44. Brech GC, Alonso AC, Luna NM, Greve JM., Correlation of postural balance and knee muscle strength in the sit-to-stand test among women with and without postmenopausal osteoporosis. Osteoporos Int. 2013 Feb 2. [Epub ahead of print].
45. Annweiler C, Allali G, Allain P, Bridenbaugh S, Schott AM, Kressig RW, Beauchet O., Vitamin D and cognitive performance in adults: a systematic review. Eur J Neurol. 2009; 16 (10): 1083-9.
46. Brunner RL, Cochrane B, Jackson RD, Larson J, Lewis C, Limacher M, Rosal M, Shumaker S, Wallace R., Calcium, vitamin D supplementation, and physical function in the Women's Health Initiative. J Am Diet Assoc. 2008; 108 (9): 1472-9.
47. Pfeifer M, Begerow B, Minne HW, Abrams C, Nachtigall D, Hansen C., Effects of a short-term vitamin D and calcium supplementation on body sway and secondary hyperparathyroidism in elderly women. J Bone Miner Res. 2000; 15 (6): 1113-8.
48. Dukas L, Staehelin HB, Schacht E, Bischoff HA., Better functional mobility in community-dwelling elderly is related to D-hormone serum levels and to daily calcium intake. J Nutr Health Aging. 2005; 9 (5): 347-51.
49. Marantes I, Achenbach SJ, Atkinson EJ, Khosla S, Melton LJ 3rd, Amin S., Is vitamin D a determinant of muscle mass and strength?. J Bone Miner Res. 2011; 26 (12): 2860-71.
50. Leblanc ES, Rizzo JH, Pedula KL, Ensrud KE, Cauley J, Hochberg M, Hillier TA., Associations between 25-hydroxyvitamin D and weight gain in elderly women. J Women's Health (Larchmt). 2012; 21 (10): 1066-73.