Three new neuritogenic steroidal saponins from Ophiopogon japonicus (Thunb.) Ker-Gawl

Steroids

Volumn 78, Issue 12-13, 2013, Pages 1171-1176

  Ye, Ying ^a   Qu, Yuan ^a   Tang, Ruiqi ^a   Cao, Shining ^a   Yang, Wei ^a   Xiang, Lan ^a   Qi, Jianhua ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

ERK phosphorylation; Neuritogenic activity; Ophiopogon japonicus; Steroidal saponins

Indexed keywords

25 RUSCOGENIN 1 O ALPHA L RHAMNOPYRANOSYL (1-2) [BETA D XYLOPYRANOSY (1-3)] 4 O ACETYL BETA D FUCOPYRANOSIDE; 25 RUSCOGENIN 1 O ALPHA L RHAMNOPYRANOSYL (1-2) [BETA D XYLOPYRANOSYL (1-3)] BETA D FUCOPYRANOSIDE; 25 RUSCOGENIN 1 O BETA D XYLOPYRANOSYL (1-2) [BETA D XYLOPYRANOSYL (1-3)] BETA D FUCOPYRANOSIDE; AGLYCONE; CENTRAL NERVOUS SYSTEM AGENTS; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NEORUSCOGENIN 1 O ALPHA L RHAMNOPYRANOSYL (1-3) ALPHA L RHAMNOPYRANOSYL (1-2) BETA D FUCOPYRANOSIDE; SAPONIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DERIVATIZATION; DRUG ACTIVITY; DRUG ISOLATION; ENZYME ACTIVATION; NEURITOGENIC ACTIVITY; NONHUMAN; OPHIOPOGON JAPONICUS; PLANT ROOT; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; WESTERN BLOTTING;

OPHIOPOGON JAPONICUS;

ERK PHOSPHORYLATION; NEURITOGENIC ACTIVITY; OPHIOPOGON JAPONICUS; STEROIDAL SAPONINS;

ANIMALS; MAP KINASE SIGNALING SYSTEM; NEURITES; OPHIOPOGON; PC12 CELLS; PLANT EXTRACTS; RATS; SAPONINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84884339779     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2013.08.005     Document Type: Article

References (22)

1. R. Levi-Montalcini The nerve growth factor 35 years later Science 237 1987 1154 1162 (Pubitemid 17124912)
2. K. Heese, J.W. Low, and N. Inoue Nerve growth factor, neural stem cells and Alzheimer's disease Neurosignals 15 2006 1 12 (Pubitemid 44131419)
3. B.A. Yankner, A. Caceres, and L.K. Duffy Nerve growth factor potentiates the neurotoxicity of beta amyloid Proc Natl Acad Sci USA 87 1990 9020 9023 (Pubitemid 120007641)
4. W. Fischer, K. Wictorin, A. Björklund, L.R. Williams, S. Varon, and F.H. Gage Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor Nature 329 1987 65 68 (Pubitemid 17125895)
5. V.E. Koliatsos, R.E. Clatterbuck, H.J.W. Nauta, B. Knüsel, L.E. Burton, and F.F. Hefti Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates Ann Neurol 30 1991 831 840
6. M.H. Tuszynski, L. Thal, M. Pay, D.P. Salmon, U.H. Sang, and R. Bakay A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease Nat Med 11 2005 551 555 (Pubitemid 40691288)
7. A.C. Granholm, D. Albeck, C. Bäckman, M. Curtis, T. Ebendal, and P. Friden A non-invasive system for delivering neural growth factors across the blood-brain barrier: a review Rev Neurosci 9 1998 31 55 (Pubitemid 28334038)
8. J. Xu, L. Trzoss, W.K. Chang, and E.A. Theodorakis Enantioselective total synthesis of (-)-jiadifenolide Angew Chem Int Ed 50 2011 3672 3676
9. X. Cheng, N. Harzdorf, Z. Khaing, D. Kang, A.M. Camelio, and T. Shaw Neuronal growth promoting sesquiterpene-neolignans; syntheses and biological studies Org Biomol Chem 10 2012 383 393
10. J. Hoecker, R. Liffert, P. Burch, R. Wehlauch, and K. Gademann Caged retinoids as photoinducible activators: implications for cell differentiation and neurite outgrowth Org Biomol Chem 11 2013 3314 3321
11. L.A. Greene, and A.S. Tischler Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor Proc Natl Acad Sci USA 73 1976 2424 2428
12. L.J. Gao, J.Y. Li, and J.H. Qi Gentisides A and B, two new neuritogenic compounds from the traditional Chinese medicine Gentiana rigescens Franch Bioorg Med Chem 18 2010 2131 2134
13. L.J. Gao, L. Xiang, Y. Luo, G.F. Wang, J.Y. Li, J.H. Qi, and C.-K. Gentisides Nine new neuritogenic compounds from the traditional Chinese medicine Gentiana rigescens Franch Bioorg Med Chem 18 2010 6995 7000
14. Y. Qu, Y. Zhang, L. Pei, Y. Wang, L. Gao, and Q.M. Huang New neuritogenic steroidal saponin from Ophiopogon japonicus (Thunb.) Ker-Gawl Biosci Biotechnol Biochem 75 2011 1201 1204
15. Y. Watanabe, S. Sanada, Y. Ida, and J. Shoji Comparative studies on the constituents of ophiopogonis tuber and its congeners. I. Studies of the constituents of the subterranean part of Liriope platyphylla WANG et TANG. (1) Chem Pharm Bull 31 1983 1980 1990
16. T. Tanaka, T. Nakashima, T. Ueda, K. Tomii, and I. Kouno Facile discrimination of aldose enantiomers by reversed-phase HPLC Chem Pharm Bull (Tokyo) 55 2007 899 901 (Pubitemid 46890090)
17. F. Berrué, M.W. McCulloch, P. Boland, S. Hart, M.K. Harper, J. Johnston, and R. Kerr Isolation of steroidal glycosides from the Caribbean sponge Pandaros acanthifolium J Nat Prod 75 2012 2094 2100
18. Y. Mimaki, Y. Takaashi, M. Kuroda, Y. Sashida, and T. Nikaido Steroidal saponins from Nolina recurvata stems and their inhibitory activity on cyclic AMP phosphodiesterase Phytochemistry 42 1996 1609 1615 (Pubitemid 27065657)
19. B.Y. Yu, S.X. Qiu, K. Zaw, G.J. Xu, Y. Hirai, and J. Shoji Steroidal glycosides from the subterranean parts of Liriope spicata var. prolifera Phytochemistry 43 1996 201 206 (Pubitemid 27065615)
20. Y. Luo, K.Y. Sun, L. Li, L.J. Gao, G.F. Wang, and Y. Qu Structure-activity relationships of neuritogenic gentiside derivatives ChemMedChem 6 2011 1986 1989
21. S.L. Rankin, C.S. Guy, and K.M. Mearow TrkA NGF receptor plays a role in the modulation of p75NTR expression Neurosci Lett 383 2005 305 310 (Pubitemid 40805575)
22. D. Vaudry, P.J.S. Stork, P. Lazarovici, and L.E. Eiden Signaling pathways for PC12 cell differentiation: making the right connections Science 296 2002 1648 1649 (Pubitemid 34579153)