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Volumn 23, Issue 10, 2013, Pages 1143-1150

Systematic review and meta-analysis of serotonin transporter genotype and discontinuation from antidepressant treatment

Author keywords

5 HTTLPR; Antidepressant; Discontinuation; Meta analysis; SSRI

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; MIRTAZAPINE; NORTRIPTYLINE; PAROXETINE; REBOXETINE; SEROTONIN TRANSPORTER; SEROTONIN TRANSPORTER GENE LINKED POLYMORPHIC REGION; SERTRALINE; UNCLASSIFIED DRUG;

EID: 84884287492     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2012.12.001     Document Type: Article
Times cited : (18)

References (55)
  • 3
    • 78650308693 scopus 로고    scopus 로고
    • Association of the 5-HTTLPR genotype and unipolar depression: a meta-analysis
    • Clarke H., Flint J., Attwood A.S., Munafo M.R. Association of the 5-HTTLPR genotype and unipolar depression: a meta-analysis. Psychol. Med. 2010, 40:1767-1778.
    • (2010) Psychol. Med. , vol.40 , pp. 1767-1778
    • Clarke, H.1    Flint, J.2    Attwood, A.S.3    Munafo, M.R.4
  • 6
    • 0029832263 scopus 로고    scopus 로고
    • Cross sectional database analysis of antidepressant prescribing in general practice in the United Kingdom, 1993-5
    • Donoghue J., Tylee A., Wildgust H. Cross sectional database analysis of antidepressant prescribing in general practice in the United Kingdom, 1993-5. Br. Med. J. 1996, 313:861-862.
    • (1996) Br. Med. J. , vol.313 , pp. 861-862
    • Donoghue, J.1    Tylee, A.2    Wildgust, H.3
  • 7
    • 4344641185 scopus 로고    scopus 로고
    • The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder
    • Durham L.K., Webb S.M., Milos P.M., Clary C.M., Seymour A.B. The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder. Psychopharmacology 2004, 174:525-529.
    • (2004) Psychopharmacology , vol.174 , pp. 525-529
    • Durham, L.K.1    Webb, S.M.2    Milos, P.M.3    Clary, C.M.4    Seymour, A.B.5
  • 8
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M., Smith G.D., Schneider M., Minder C. Bias in meta-analysis detected by a simple, graphical test. Br. Med. J. 1997, 315:629-634.
    • (1997) Br. Med. J. , vol.315 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3    Minder, C.4
  • 9
    • 0011145384 scopus 로고    scopus 로고
    • SSRI antidepressant medications: adverse effects and tolerability
    • Ferguson J.M. SSRI antidepressant medications: adverse effects and tolerability. Primary care Companion J. Clin. Psychiatry 2001, 3:22.
    • (2001) Primary care Companion J. Clin. Psychiatry , vol.3 , pp. 22
    • Ferguson, J.M.1
  • 12
    • 70349513258 scopus 로고    scopus 로고
    • Emerging role of glutamate in the pathophysiology of major depressive disorder
    • Hashimoto K. Emerging role of glutamate in the pathophysiology of major depressive disorder. Brain Res. Rev. 2009, 61:105-123.
    • (2009) Brain Res. Rev. , vol.61 , pp. 105-123
    • Hashimoto, K.1
  • 15
    • 70449714178 scopus 로고    scopus 로고
    • Influence of serotonergic/noradrenergic gene polymorphisms on nausea and sweating induced by milnacipran in the treatment of depression
    • Higuchi H., Takahashi H., Kamata M., Yoshida K. Influence of serotonergic/noradrenergic gene polymorphisms on nausea and sweating induced by milnacipran in the treatment of depression. Neuropsychiatr. Dis. Treat. 2009, 5:393-398.
    • (2009) Neuropsychiatr. Dis. Treat. , vol.5 , pp. 393-398
    • Higuchi, H.1    Takahashi, H.2    Kamata, M.3    Yoshida, K.4
  • 22
    • 0242552727 scopus 로고    scopus 로고
    • Is there an association between serotonin transporter gene polymorphism and family history of depression?
    • Joiner T.E., Johnson F., Soderstrom K., Brown J.S. Is there an association between serotonin transporter gene polymorphism and family history of depression?. J. Affect. Disord. 2003, 77:273-275.
    • (2003) J. Affect. Disord. , vol.77 , pp. 273-275
    • Joiner, T.E.1    Johnson, F.2    Soderstrom, K.3    Brown, J.S.4
  • 23
    • 0742305531 scopus 로고    scopus 로고
    • Age-dependent antidepressant pharmacogenomics: polymorphisms of the serotonin transporter and G protein beta 3 subunit as predictors of response to fluoxetine and nortriptyline
    • Joyce P.R., Mulder R.T., Luty S.E., McKenzie J.M., Miller A.L., Rogers G.R., Kennedy M.A. Age-dependent antidepressant pharmacogenomics: polymorphisms of the serotonin transporter and G protein beta 3 subunit as predictors of response to fluoxetine and nortriptyline. Int. J. Neuropsychopharmacol. 2003, 6:339-346.
    • (2003) Int. J. Neuropsychopharmacol. , vol.6 , pp. 339-346
    • Joyce, P.R.1    Mulder, R.T.2    Luty, S.E.3    McKenzie, J.M.4    Miller, A.L.5    Rogers, G.R.6    Kennedy, M.A.7
  • 24
    • 84884282739 scopus 로고    scopus 로고
    • Association study of the 5-HTT polymorphism and mirtazapine antidepressant response in major depressive disorder
    • Kang R.H., Kim J.G., Choi M.J., Lee H.W., Kang S.G., Lee H.J., Lee M.S. Association study of the 5-HTT polymorphism and mirtazapine antidepressant response in major depressive disorder. Eur. Neuropsychopharmacol. 2007, 17:S322-S323.
    • (2007) Eur. Neuropsychopharmacol. , vol.17
    • Kang, R.H.1    Kim, J.G.2    Choi, M.J.3    Lee, H.W.4    Kang, S.G.5    Lee, H.J.6    Lee, M.S.7
  • 25
    • 34447565937 scopus 로고    scopus 로고
    • Association study of the serotonin transporter promoter polymorphism and mirtazapine antidepressant response in major depressive disorder
    • Kang R.H., Wong M.L., Choi M.J., Paik J.W., Lee M.S. Association study of the serotonin transporter promoter polymorphism and mirtazapine antidepressant response in major depressive disorder. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 2007, 31:1317-1321.
    • (2007) Prog. Neuro-Psychopharmacol. Biol. Psychiatry , vol.31 , pp. 1317-1321
    • Kang, R.H.1    Wong, M.L.2    Choi, M.J.3    Paik, J.W.4    Lee, M.S.5
  • 26
    • 33747396949 scopus 로고    scopus 로고
    • Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients
    • Kato M., Fukuda T., Wakeno M., Fukuda K., Okugawa G., Ikenaga Y., Yamashita M., Takekita Y., Nobuhara K., Azuma J., Kinoshita T. Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients. Neuropsychobiology 2006, 53:186-195.
    • (2006) Neuropsychobiology , vol.53 , pp. 186-195
    • Kato, M.1    Fukuda, T.2    Wakeno, M.3    Fukuda, K.4    Okugawa, G.5    Ikenaga, Y.6    Yamashita, M.7    Takekita, Y.8    Nobuhara, K.9    Azuma, J.10    Kinoshita, T.11
  • 28
    • 77951844279 scopus 로고    scopus 로고
    • Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder
    • Kato M., Serretti A. Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder. Mol. Psychiatry 2010, 15:473-500.
    • (2010) Mol. Psychiatry , vol.15 , pp. 473-500
    • Kato, M.1    Serretti, A.2
  • 30
    • 0031423428 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder
    • Kunugi H., Hattori M., Kato T., Tatsumi M., Sakai T., Sasaki T., Hirose T., Nanko S. Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder. Mol. Psychiatry 1997, 2:457-462.
    • (1997) Mol. Psychiatry , vol.2 , pp. 457-462
    • Kunugi, H.1    Hattori, M.2    Kato, T.3    Tatsumi, M.4    Sakai, T.5    Sasaki, T.6    Hirose, T.7    Nanko, S.8
  • 34
    • 65049084627 scopus 로고    scopus 로고
    • Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression
    • Maron E., Tammiste A., Kallassalu K., Eller T., Vasar V., Nutt D.J., Metspalu A. Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression. Eur. Neuropsychopharmacol. 2009, 19:451-456.
    • (2009) Eur. Neuropsychopharmacol. , vol.19 , pp. 451-456
    • Maron, E.1    Tammiste, A.2    Kallassalu, K.3    Eller, T.4    Vasar, V.5    Nutt, D.J.6    Metspalu, A.7
  • 36
    • 7744233997 scopus 로고    scopus 로고
    • Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression
    • Murphy G.M., Hollander S.B., Rodrigues H.E., Kremer C., Schatzberg A.F. Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression. Arch. Gen. Psychiatry 2004, 61:1163-1169.
    • (2004) Arch. Gen. Psychiatry , vol.61 , pp. 1163-1169
    • Murphy, G.M.1    Hollander, S.B.2    Rodrigues, H.E.3    Kremer, C.4    Schatzberg, A.F.5
  • 41
    • 84857236103 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy
    • Porcelli S., Fabbri C., Serretti A. Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy. Eur. Neuropsychopharmacol. 2012, 22:239-258.
    • (2012) Eur. Neuropsychopharmacol. , vol.22 , pp. 239-258
    • Porcelli, S.1    Fabbri, C.2    Serretti, A.3
  • 42
    • 58149267603 scopus 로고    scopus 로고
    • Serotonin transporter gene promoter polymorphisms modify the association between paroxetine serotonin transporter occupancy and clinical response in major depressive disorder
    • Ruhe H.G., Ooteman W., Booij J., Michel M.C., Moeton M., Baas F., Schene A.H. Serotonin transporter gene promoter polymorphisms modify the association between paroxetine serotonin transporter occupancy and clinical response in major depressive disorder. Pharmacogenet. Genomics 2009, 19:67-76.
    • (2009) Pharmacogenet. Genomics , vol.19 , pp. 67-76
    • Ruhe, H.G.1    Ooteman, W.2    Booij, J.3    Michel, M.C.4    Moeton, M.5    Baas, F.6    Schene, A.H.7
  • 44
    • 72149084933 scopus 로고    scopus 로고
    • Analysis of association between the 5-HTTLPR and STin2 polymorphisms in the serotonin-transporter gene and clinical response to a selective serotonin reuptake inhibitor (sertraline) in patients with premature ejaculation
    • Safarinejad M.R. Analysis of association between the 5-HTTLPR and STin2 polymorphisms in the serotonin-transporter gene and clinical response to a selective serotonin reuptake inhibitor (sertraline) in patients with premature ejaculation. BJU Int. 2010, 105:73-78.
    • (2010) BJU Int. , vol.105 , pp. 73-78
    • Safarinejad, M.R.1
  • 45
    • 33846229238 scopus 로고    scopus 로고
    • Serotonin transporter gene influences the time course of improvement of "core" depressive and somatic anxiety symptoms during treatment with SSRIs for recurrent mood disorders
    • Serretti A., Mandelli L., Lorenzi C., Pirovano A., Olgiati P., Colombo C., Smeraldi E. Serotonin transporter gene influences the time course of improvement of "core" depressive and somatic anxiety symptoms during treatment with SSRIs for recurrent mood disorders. Psychiatry Res. 2007, 149:185-193.
    • (2007) Psychiatry Res. , vol.149 , pp. 185-193
    • Serretti, A.1    Mandelli, L.2    Lorenzi, C.3    Pirovano, A.4    Olgiati, P.5    Colombo, C.6    Smeraldi, E.7
  • 46
    • 84884285660 scopus 로고    scopus 로고
    • StataCorp. Stata Statistical Software. StataCorp LP, College Station, TX.
    • StataCorp, 2011. Stata Statistical Software. StataCorp LP, College Station, TX.
    • (2011)
  • 47
    • 0034823867 scopus 로고    scopus 로고
    • Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis
    • Sterne J.A.C., Egger M. Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. J. Clin. Epidemiol. 2001, 54:1046-1055.
    • (2001) J. Clin. Epidemiol. , vol.54 , pp. 1046-1055
    • Sterne, J.A.C.1    Egger, M.2
  • 50
    • 77956170298 scopus 로고    scopus 로고
    • Antidepressant response and the serotonin transporter gene-linked polymorphic region
    • Taylor M.J., Sen S., Bhagwagar Z. Antidepressant response and the serotonin transporter gene-linked polymorphic region. Biol. Psychiatry 2010, 68:536-543.
    • (2010) Biol. Psychiatry , vol.68 , pp. 536-543
    • Taylor, M.J.1    Sen, S.2    Bhagwagar, Z.3
  • 51
    • 56449101949 scopus 로고    scopus 로고
    • The implications of gene-environment interactions in depression: will cause inform cure?
    • Uher R. The implications of gene-environment interactions in depression: will cause inform cure?. Mol. Psychiatry 2008, 13:1070-1078.
    • (2008) Mol. Psychiatry , vol.13 , pp. 1070-1078
    • Uher, R.1
  • 52
    • 78650157200 scopus 로고    scopus 로고
    • Predictive factors for responding to sertraline treatment: views from plasma catecholamine metabolites and serotonin transporter polymorphism
    • Umene-Nakano W., Yoshimura R., Ueda N., Suzuki A., Ikenouchi-Sugita A., Hori H., Otani K., Nakamura J. Predictive factors for responding to sertraline treatment: views from plasma catecholamine metabolites and serotonin transporter polymorphism. J. Psychopharmacol. 2010, 24:1764-1771.
    • (2010) J. Psychopharmacol. , vol.24 , pp. 1764-1771
    • Umene-Nakano, W.1    Yoshimura, R.2    Ueda, N.3    Suzuki, A.4    Ikenouchi-Sugita, A.5    Hori, H.6    Otani, K.7    Nakamura, J.8
  • 53
    • 67650446830 scopus 로고    scopus 로고
    • Long-term treatment with fluoxetine induces desensitization of 5-HT4 receptor-dependent signalling and functionality in rat brain
    • Vidal R., Valdizan E.M., Mostany R., Pazos A., Castro E. Long-term treatment with fluoxetine induces desensitization of 5-HT4 receptor-dependent signalling and functionality in rat brain. J. Neurochem. 2009, 110:1120-1127.
    • (2009) J. Neurochem. , vol.110 , pp. 1120-1127
    • Vidal, R.1    Valdizan, E.M.2    Mostany, R.3    Pazos, A.4    Castro, E.5
  • 54
    • 70349540888 scopus 로고    scopus 로고
    • Rapid response to paroxetine is associated with plasma paroxetine levels at 4 but not 8 weeks of treatment, and is independent of serotonin transporter promoter polymorphism in Japanese depressed patients
    • Yoshimura R., Umene-Nakano W., Suzuki A., Ueda N., Miyamoto K., Ikenouchi-Sugita A., Hori H., Otani K., Nakamura J. Rapid response to paroxetine is associated with plasma paroxetine levels at 4 but not 8 weeks of treatment, and is independent of serotonin transporter promoter polymorphism in Japanese depressed patients. Human Psychopharmacol.-Clin. Exp. 2009, 24:489-494.
    • (2009) Human Psychopharmacol.-Clin. Exp. , vol.24 , pp. 489-494
    • Yoshimura, R.1    Umene-Nakano, W.2    Suzuki, A.3    Ueda, N.4    Miyamoto, K.5    Ikenouchi-Sugita, A.6    Hori, H.7    Otani, K.8    Nakamura, J.9


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