Operationalization of frailty using eight commonly used scales and comparison of their ability to predict all-cause mortality

Journal of the American Geriatrics Society

Volumn 61, Issue 9, 2013, Pages 1537-1551

  Theou, Olga ^a   Brothers, Thomas D ^a   Mitnitski, Arnold ^a   Rockwood, Kenneth ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

aging; Europe; frail older adults; health status indicators; prognosis

Indexed keywords

70 ITEM FRAILTY INDEX; ACCURACY; ADULT; AGED; ARTICLE; CLINICAL FRAILTY SCALE; COMPREHENSIVE GERIATRIC ASSESSMENT; CONTENT VALIDITY; EDMONTON FRAIL SCALE; FEASIBILITY STUDY; FEMALE; FRAIL ELDERLY; FRAIL SCALE; GRONINGEN FRAILTY INDICATOR; HUMAN; HUMAN EXPERIMENT; INTERMETHOD COMPARISON; MALE; MORTALITY; PHENOTYPE; PREVALENCE; RATING SCALE; TILBURG FRAILTY INDICATOR;

AGING; EUROPE; FRAIL OLDER ADULTS; HEALTH STATUS INDICATORS; PROGNOSIS;

AGED; AGED, 80 AND OVER; CAUSE OF DEATH; EUROPE; FEMALE; FRAIL ELDERLY; GERIATRIC ASSESSMENT; HEALTH SURVEYS; HUMANS; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; SURVIVAL RATE;

EID: 84884281845     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/jgs.12420     Document Type: Article

References (54)

1. Vaupel JW,. Biodemography of human ageing. Nature 2010; 464: 536-542.
2. Rodriguez-Manas L, Feart C, Mann G, et al. Searching for an operational definition of frailty: A Delphi method based consensus statement. The Frailty Operative Definition-Consensus Conference Project. J Gerontol A Biol Sci Med Sci 2012; 68A: 62-67.
3. Theou O, Rockwood K,. Should frailty status always be considered when treating the elderly patient? Aging Health 2012; 8: 261-271.
4. Auyeung TW, Lee JS, Kwok T, et al. Physical frailty predicts future cognitive decline: A four-year prospective study in 2737 cognitively normal older adults. J Nutr Health Aging 2011; 15: 690-694.
5. Mitnitski A, Fallah N, Rockwood MR, et al. Transitions in cognitive status in relation to frailty in older adults: A comparison of three frailty measures. J Nutr Health Aging 2011; 15: 863-867.
6. Hurria A, Togawa K, Mohile SG, et al. Predicting chemotherapy toxicity in older adults with cancer: A prospective multicenter study. J Clin Oncol 2011; 29: 3457-3465.
7. Makary MA, Segev DL, Pronovost PJ, et al. Frailty as a predictor of surgical outcomes in older patients. J Am Coll Surg 2010; 210: 901-908.
8. Hastings SN, Purser JL, Johnson KS, et al. Frailty predicts some but not all adverse outcomes in older adults discharged from the emergency department. J Am Geriatr Soc 2008; 56: 1651-1657.
9. Gill TM, Gahbauer EA, Han L, et al. Trajectories of disability in the last year of life. N Engl J Med 2010; 362: 1173-1180.
10. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: Evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56A: M146-M156.
11. Mitnitski AB, Mogilner AJ, Rockwood K,. Accumulation of deficits as a proxy measure of aging. ScientificWorld 2001; 1: 323-336.
12. de Vries NM, Staal JB, van Ravensberg CD, et al. Outcome instruments to measure frailty: A systematic review. Ageing Res Rev 2011; 10: 104-114.
13. Theou O, Kloseck M,. Tools to identify community-dwelling older adults in different stages of frailty. Phys Occup Ther Geriatr 2007; 26: 1-21.
14. Cigolle CT, Ofstedal MB, Tian Z, et al. Comparing models of frailty: The Health and Retirement Study. J Am Geriatr Soc 2009; 57: 830-839.
15. Woo J, Leung J, Morley JE,. Comparison of frailty indicators based on clinical phenotype and the multiple deficit approach in predicting mortality and physical limitation. J Am Geriatr Soc 2012; 60: 1478-1486.
16. Martin FC, Brighton P,. Frailty: Different tools for different purposes? Age Ageing 2008; 37: 129-131.
17. United Nations Department of Economic and Social Affairs, Population Division. Population ageing and development 2012 [on-line]. Available at http://www.un.org/esa/population/publications/2012WorldPopAgeingDev-Chart/ 2012PopAgeingandDev-WallChart.pdf Accessed December 12, 2012.
18. Santos-Eggiman B, Cuenod P, Spagnoli J, et al. Prevalence of frailty in middle-aged and older community-dwelling Europeans living in 10 countries. J Gerontol A Biol Sci Med Sci 2009; 64A: 675-681.
19. Börsch-Supan A, Jürges H,. The Survey of Health, Ageing and Retirement in Europe-Methodology. Mannheim, Germany: Mannheim Research Institute for the Economics of Aging, 2005.
20. Börsch-Supan A, Brugiavini A, Jürges H, et al. Health, ageing and retirement in Europe-First results from the Survey of Health, Ageing and Retirement in Europe. Mannheim, Germany: Mannheim Research Institute for the Economics of Aging, 2005.
21. Schuurmans H, Steverink N, Lindenberg S, et al. Old or frail: What tells us more? J Gerontol A Biol Sci Med Sci 2004; 59A: M962-M965.
22. Gobbens RJJ, van Assen MALM, Luijkx KG, et al. The Tilburg frailty indicator: Psychometric properties. J Am Med Dir Assoc 2010; 11: 344-355.
23. Jones DM, Song X, Rockwood K,. Operationalizing a frailty index from a standardized comprehensive geriatric assessment. J Am Geriatr Soc 2004; 52: 1929-1933.
24. Rockwood K, Song X, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people. Can Med Assoc J 2005; 173: 489-495.
25. Rolfson DB, Majumdar SR, Tsuyuki RT, et al. Validity and reliability of the Edmonton Frail Scale. Age Ageing 2006; 35: 526-529.
26. Abellan Van Kan G, Rolland Y, Morley JE, et al. Frailty: Toward a clinical definition. J Am Dir Assoc 2008; 9: 71-72.
27. Shanmugasegaram S, Gagliese L, Oh P, et al. Psychometric validation of the cardiac rehabilitation barriers scale. Clin Rehabil 2012; 26: 152-164.
28. World Health Organization Programme on Mental Health. WHOQOL-BREF Introduction, Administration and Scoring. Geneva: World Health Organization, 1996 [on-line]. Available at http://www.who.int/mental-health/media/en/76.pdf Accessed December 12, 2012.
29. Peters LL, Boter H, Buskens E, et al. Measurement properties of the Groningen Frailty Indicator in home-dwelling and institutionalized elderly people. J Am Med Dir Assoc 2012; 13: 546-551.
30. Prince MJ, Reisches F, Beekman AT, et al. Development of the EURO-D scale-a European Union initiative to compare symptoms of depression in 14 European centres. Br J Psychiatry 1999; 174: 330-338.
31. Rockwood K, Mitnitski A,. Frailty defined by deficit accumulation and geriatric medicine defined by frailty. Clin Geriatr Med 2011; 27: 17-26.
32. Searle SD, Mitnitski A, Gahbauer EA, et al. A standard procedure for creating a frailty index. BMC Geriatr 2008; 8: 24e.
33. Romero-Ortuno R, Kenny RA,. The frailty index in Europeans: Association with age and mortality. Age Ageing 2012; 41: 684-689.
34. Theou O, Brothers TD, Rockwood MR, et al. Exploring the relationship between national economic indicators and relative fitness and frailty in middle-aged and older Europeans. Age Ageing 2013; 000: 000-000 [Epub ahead of print].
35. Rockwood K, Andrew M, Mitnitski A,. A comparison of two approaches to measuring frailty in elderly people. J Gerontol A Biol Sci Med Sci 2007; 62A: 738-743.
36. Romero-Ortuno R, Walsh CD, Lawlor BA, et al. A frailty instrument for primary care: Findings from the Survey of Health, Ageing and Retirement in Europe (SHARE). BMC Geriatr 2010; 10: 57e.
37. Hilmer SN, Perera V, Mitchell S, et al. The assessment of frailty in older people in acute care. Australas J Ageing 2009; 28: 182-188.
38. Hyde Z, Flicker L, Almeida OP, et al. Low free testosterone predicts frailty in older men: The Health in Men Study. J Clin Endocrinol Metab 2010; 95: 3165-3172.
39. Saum KU, Müller H, Stegmaier C, et al. Development and evaluation of a modification of the Fried frailty criteria using population-independent cutpoints. J Am Geriatr Soc 2012; 60: 2110-2115.
40. Freiheit EA, Hogan DB, Strain LA, et al. Operationalizing frailty among older residents of assisted living facilities. BMC Geriatr 2011; 11: 23e.
41. Bartali B, Frongillo EA, Bandinelli S, et al. Low nutrient intake is an essential component of frailty in older persons. J Gerontol A Biol Sci Med Sci 2006; 61A: 589-593.
42. Hoogendijk EO, van der Horst HE, Deeg DJ, et al. The identification of frail older adults in primary care: Comparing the accuracy of five simple instruments. Age Ageing 2013; 42: 262-265.
43. Rockwood K, Jones D, Wang Y, et al. Failure to complete performance-based measures is associated with poor health status and an increased risk of death. Age Ageing 2007; 36: 225-228.
44. Mitnitski A, Song X, Skoog I, et al. Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J Am Geriatr Soc 2005; 53: 2184-2189.
45. Collard RM, Boter H, Schoevers RA, et al. Prevalence of frailty in community-dwelling older persons: A systematic review. J Am Geriatr Soc 2012; 60: 1497-1492.
46. Sternberg SA, Wershof Schwartz A, Karunananthan S, et al. The identification of frailty: A systematic literature review. J Am Geriatr Soc 2011; 59: 2129-2138.
47. Rockwood K,. What would make a definition of frailty successful? Age Ageing 2005; 34: 432-434.
48. Kulminski AM, Ukrainsteva SV, Kulminskaya IV, et al. Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: Lessons from the Cardiovascular Health Study. J Am Geriatr Soc 2008; 56: 898-903.
49. Daniels R, van Rossum E, Beurskens A, et al. The predictive validity of three self-report screening instruments for identifying frail older people in the community. BMC Public Health 2012; 12: 69.
50. Kamaruzzaman S, Ploubidis GB, Fletcher A, et al. A reliable measure of frailty for a community dwelling older population. Health Qual Life Outcomes 2010; 8: 123.
51. Song X, Mitnitski A, MacKnight C, et al. Assessment of individual risk of death using self-report data: An artificial neural network compared with a frailty index. J Am Geriatr Soc 2004; 52: 1180-1184.
52. Romero-Ortuno R,. The Frailty Instrument for primary care of the Survey of Health, Ageing and Retirement in Europe predicts mortality similarly to a frailty index based on comprehensive geriatric assessment. Geriatr Gerontol Int 2013; 13: 497-504.
53. King-Kallimanis B, Sawa G, Kenny RA,. Using structural equation modelling to detect measurement invariance in a measure of frailty. Eur Geriatr Med 2012; 3 (Suppl 1): 17.
54. Romero-Ortuno R,. The Frailty Instrument for primary care of the Survey of Health, Ageing and Retirement in Europe (SHARE-FI): Results of the Spanish sample. Rev Esp Geriatr Gerontol 2011; 46: 243-249.