Integrated Evaluation of Central Nervous System Lesions: StainS for Neurons, Astrocytes, and Microglia Reveal the Spatial and Temporal Features of MK-801-induced Neuronal Necrosis in the Rat Cerebral Cortex

Toxicologic Pathology

Volumn 24, Issue 3, 1996, Pages 291-304

  Fix, Andrew S ^a   Ross, Joseph F ^a   Stitzel, Susan R ^a   Switzer, Robert C ^b  

^a PROCTER AND GAMBLE COMPANY   (United States)

^b Neuroscience Associates   (United States)

Author keywords

Brain; cupric silver stain; dizocilpine maleate; GFAP immunohistochemistry; glial fibrillary acidic protein (GFAP); lectin histochemistry; neuropathology; neurotoxicity; risk assessment; toxicity

Indexed keywords

DIZOCILPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN NECROSIS; CONTROLLED STUDY; HISTOCHEMISTRY; HISTOPATHOLOGY; MALE; MICROGLIA; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SILVER STAINING; TOXICITY TESTING;

ANIMALS; ASTROCYTES; CENTRAL NERVOUS SYSTEM DISEASES; CEREBRAL CORTEX; COLORING AGENTS; COPPER; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; NECROSIS; NERVE DEGENERATION; NEURONS; PARAFFIN EMBEDDING; RATS; RATS, SPRAGUE-DAWLEY; SILVER STAINING;

ANIMALIA; GRIFFONIA SIMPLICIFOLIA;

EID: 0029894380     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339602400305     Document Type: Article

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