Male Sprague-Dawley rats exposed to in utero di(n-butyl) phthalate: Dose dependent and age-related morphological changes in leydig cell smooth endoplasmic reticulum

Toxicologic Pathology

Volumn 41, Issue 7, 2013, Pages 984-991

  Shirai, Masaru ^a   Wakui, Shin ^a,b   Wempe, Michael F ^c   Mutou, Tomoko ^d   Oyama, Noriko ^d   Motohashi, Masaya ^a   Takahashi, Hiroyuki ^b   Kansaku, Norio ^a   Asari, Masao ^a   Hano, Hiroshi ^b   Endou, Hitoshi ^e  

^a AZABU UNIVERSITY   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF COLORADO   (United States)

^d Drug Safety Testing Center   (Japan)

^e J Pharma Co   (Japan)

Author keywords

electron microscopy; Leydig cell; prenatal DBP exposure to rats; smooth endoplasmic reticulum; testis

Indexed keywords

LUTEINIZING HORMONE; PHTHALIC ACID DIBUTYL ESTER; TESTOSTERONE;

AGE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; FEMALE; GESTATION PERIOD; LEYDIG CELL; LITTER SIZE; LUTEINIZING HORMONE BLOOD LEVEL; MALE; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; SEX RATIO; SMOOTH ENDOPLASMIC RETICULUM; SPRAGUE DAWLEY RAT; TESTOSTERONE BLOOD LEVEL;

ELECTRON MICROSCOPY; LEYDIG CELL; PRENATAL DBP EXPOSURE TO RATS; SMOOTH ENDOPLASMIC RETICULUM; TESTIS.;

AGE FACTORS; ANIMALS; BODY WEIGHT; DIBUTYL PHTHALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM, SMOOTH; FEMALE; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; MATERNAL EXPOSURE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; TESTIS; TESTOSTERONE;

EID: 84884241810     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623312474725     Document Type: Article

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