Biodistribution and Subcellular Localization of an Unnatural Boron-Containing Amino Acid (Cis-ABCPC) by Imaging Secondary Ion Mass Spectrometry for Neutron Capture Therapy of Melanomas and Gliomas

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Chandra, Subhash ^a   Barth, Rolf F ^b   Haider, Syed A ^a,d   Yang, Weilian ^b   Huo, Tianyao ^b,e   Shaikh, Aarif L ^c   Kabalka, George W ^c  

^a Cornell University   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TENNESSEE   (United States)

^d RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINO 3 BORONO CYCLOPENTANECARBOXYLIC ACID; 4 BORONOPHENYLALANINE; AMINO ACID DERIVATIVE; AMINO ACID TRANSPORTER; BORON; DRUG CARRIER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CANCER GRADING; CELL CYCLE; CELL CYCLE S PHASE; CELL INFILTRATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG STRUCTURE; DRUG UPTAKE; ENANTIOMER; EXTRACELLULAR MATRIX; FEMALE; GLIOMA; HUMAN; HUMAN CELL; IMAGING; IN VITRO STUDY; IN VIVO STUDY; MALE; MASS SPECTROMETRY; MELANOMA; MOUSE; NEUTRON CAPTURE THERAPY; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; UPREGULATION;

AMINO ACIDS; ANIMALS; BLOOD-BRAIN BARRIER; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; BRAIN NEOPLASMS; GLIOMA; HUMANS; MALE; MELANOMA; NEOPLASMS, EXPERIMENTAL; RATS; RATS, INBRED F344; S PHASE; SPECTROMETRY, MASS, SECONDARY ION;

EID: 84884238683     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075377     Document Type: Article

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