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Volumn 39, Issue 3, 2013, Pages 489-496

SuPAR and PAI-1 in critically ill, mechanically ventilated patients

Author keywords

Acute respiratory distress syndrome (ARDS); Acute respiratory failure (ARF); Biomarkers; Plasminogen activator inhibitor 1 (PAI 1); Soluble urokinase plasminogen activator receptor (suPAR)

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR 1; UROKINASE RECEPTOR;

EID: 84884213392     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-012-2730-x     Document Type: Article
Times cited : (42)

References (35)
  • 1
    • 72949116366 scopus 로고    scopus 로고
    • Regulation of cell signalling by uPAR
    • 20027185 10.1038/nrm2821 1:CAS:528:DC%2BD1MXhsFymtb7M
    • Smith HV, Marshall CJ (2010) Regulation of cell signalling by uPAR. Nat Rev Mol Cell Biol 11:23-36
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 23-36
    • Smith, H.V.1    Marshall, C.J.2
  • 2
    • 0037394513 scopus 로고    scopus 로고
    • Coagulation, fibrinolysis, and fibrin deposition in acute lung injury
    • 12682443 10.1097/01.CCM.0000057846.21303.AB 1:CAS:528: DC%2BD3sXis12qtLs%3D
    • Idell S (2003) Coagulation, fibrinolysis, and fibrin deposition in acute lung injury. Crit Care Med 31(4 Suppl):S213-S220
    • (2003) Crit Care Med , vol.31 , Issue.SUPPL. 4
    • Idell, S.1
  • 4
    • 54049118045 scopus 로고    scopus 로고
    • Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury
    • 18358078 10.1186/cc6846
    • McClintock D, Zhuo H, Wickersham N, Matthay MA, Ware LB (2008) Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury. Crit Care 12:R41
    • (2008) Crit Care , vol.12 , pp. 41
    • McClintock, D.1    Zhuo, H.2    Wickersham, N.3    Matthay, M.A.4    Ware, L.B.5
  • 5
    • 76749100153 scopus 로고    scopus 로고
    • Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury
    • NHLBI ARDS Clinical Trials Network 19858233 10.1378/chest.09-1484
    • Ware LB, Koyama T, Billheimer DD, Wu W, Bernard GR, Thompson BT, Brower RG, Standiford TJ, Martin TR, Matthay MA, NHLBI ARDS Clinical Trials Network (2009) Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest 137:288-296
    • (2009) Chest , vol.137 , pp. 288-296
    • Ware, L.B.1    Koyama, T.2    Billheimer, D.D.3    Wu, W.4    Bernard, G.R.5    Thompson, B.T.6    Brower, R.G.7    Standiford, T.J.8    Martin, T.R.9    Matthay, M.A.10
  • 6
    • 80052050835 scopus 로고    scopus 로고
    • Acute respiratory distress syndrome and acute lung injury
    • 21642654 10.1136/pgmj.2011.118398 1:CAS:528:DC%2BC3MXhtlGjtbfO
    • Dushianthan A, Grocott MP, Postle AD, Cusack R (2011) Acute respiratory distress syndrome and acute lung injury. Postgrad Med J 87:612-622
    • (2011) Postgrad Med J , vol.87 , pp. 612-622
    • Dushianthan, A.1    Grocott, M.P.2    Postle, A.D.3    Cusack, R.4
  • 8
    • 0242525181 scopus 로고    scopus 로고
    • Plasma surfactant protein levels and clinical outcomes in patients with acute lung injury
    • Acute Respiratory Distress Syndrome Network 14586055 10.1136/thorax.58. 11.983 1:STN:280:DC%2BD3srjvVCjtg%3D%3D
    • Eisner MD, Parsons P, Matthay MA, Ware L, Greene K, Acute Respiratory Distress Syndrome Network (2003) Plasma surfactant protein levels and clinical outcomes in patients with acute lung injury. Thorax 58:983-988
    • (2003) Thorax , vol.58 , pp. 983-988
    • Eisner, M.D.1    Parsons, P.2    Matthay, M.A.3    Ware, L.4    Greene, K.5
  • 9
    • 77949457996 scopus 로고    scopus 로고
    • Plasma levels of surfactant protein D and KL-6 for evaluation of lung injury in critically ill mechanically ventilated patients
    • 20158912 10.1186/1471-2466-10-6
    • Determann RM, Royakkers AA, Haitsma JJ, Zhang H, Slutsky AS, Ranieri VM, Schultz MJ (2010) Plasma levels of surfactant protein D and KL-6 for evaluation of lung injury in critically ill mechanically ventilated patients. BMC Pulm Med 10:6
    • (2010) BMC Pulm Med , vol.10 , pp. 6
    • Determann, R.M.1    Royakkers, A.A.2    Haitsma, J.J.3    Zhang, H.4    Slutsky, A.S.5    Ranieri, V.M.6    Schultz, M.J.7
  • 10
    • 70449637194 scopus 로고    scopus 로고
    • Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: A systematic review and meta-analysis
    • NGAL Meta-analysis Investigator Group 19850388 10.1053/j.ajkd.2009.07.020 1:CAS:528:DC%2BC3cXkvFKqsA%3D%3D
    • Haase M, Bellomo R, Devarajan P, Schlattmann P, Haase-Fielitz A, NGAL Meta-analysis Investigator Group (2009) Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis 54:1012-1024
    • (2009) Am J Kidney Dis , vol.54 , pp. 1012-1024
    • Haase, M.1    Bellomo, R.2    Devarajan, P.3    Schlattmann, P.4    Haase-Fielitz, A.5
  • 11
    • 84863007624 scopus 로고    scopus 로고
    • Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia
    • Genetic and Inflammatory Markers of Sepsis (GenIMS) Study Investigators 21677634 10.1038/ki.2011.160 1:CAS:528:DC%2BC3MXhtVWnurnN
    • Srisawat N, Murugan R, Lee M, Kong L, Carter M, Angus DC, Kellum JA, Genetic and Inflammatory Markers of Sepsis (GenIMS) Study Investigators (2011) Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia. Kidney Int 80:545-552
    • (2011) Kidney Int , vol.80 , pp. 545-552
    • Srisawat, N.1    Murugan, R.2    Lee, M.3    Kong, L.4    Carter, M.5    Angus, D.C.6    Kellum, J.A.7
  • 12
    • 1242306694 scopus 로고    scopus 로고
    • Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumonia
    • 14760153 10.1136/thorax.2003.013888 1:STN:280:DC%2BD2c%2FnvFWjsA%3D%3D
    • Schultz MJ, Millo J, Levi M, Hack CE, Weverling GJ, Garrard CS, van der Poll T (2004) Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumonia. Thorax 59:130-135
    • (2004) Thorax , vol.59 , pp. 130-135
    • Schultz, M.J.1    Millo, J.2    Levi, M.3    Hack, C.E.4    Weverling, G.J.5    Garrard, C.S.6    Van Der Poll, T.7
  • 14
    • 0346881256 scopus 로고    scopus 로고
    • Clinical significance of urokinase-type plasminogen activator receptor (uPAR) expression in cancer
    • 14595671 10.1002/med.10054
    • de Bock CE, Wang Y (2004) Clinical significance of urokinase-type plasminogen activator receptor (uPAR) expression in cancer. Med Res Rev 24:13-39
    • (2004) Med Res Rev , vol.24 , pp. 13-39
    • De Bock, C.E.1    Wang, Y.2
  • 15
    • 73349125115 scopus 로고    scopus 로고
    • SuPAR: The molecular crystal ball
    • 19893210
    • Thunø M, Macho B, Eugen-Olsen J (2009) suPAR: the molecular crystal ball. Dis Markers 27:157-172
    • (2009) Dis Markers , vol.27 , pp. 157-172
    • Thunø, M.1    Macho, B.2    Eugen-Olsen, J.3
  • 16
    • 2642563088 scopus 로고    scopus 로고
    • The plasma level of soluble urokinase receptor is elevated in patients with Streptococcus pneumoniae bacteraemia and predicts mortality
    • 15113317 10.1111/j.1469-0691.2004.00850.x 1:CAS:528:DC%2BD2cXkvFCntrw%3D
    • Wittenhagen P, Kronborg G, Weis N, Nielsen H, Obel N, Pedersen SS, Eugen-Olsen J (2004) The plasma level of soluble urokinase receptor is elevated in patients with Streptococcus pneumoniae bacteraemia and predicts mortality. Clin Microbiol Infect 10:409-415
    • (2004) Clin Microbiol Infect , vol.10 , pp. 409-415
    • Wittenhagen, P.1    Kronborg, G.2    Weis, N.3    Nielsen, H.4    Obel, N.5    Pedersen, S.S.6    Eugen-Olsen, J.7
  • 17
    • 79959331335 scopus 로고    scopus 로고
    • Plasma level of soluble urokinase-type plasminogen activator receptor as a predictor of disease severity and case fatality in patients with bacteraemia: A prospective cohort study
    • 21332843 10.1111/j.1365-2796.2011.02363.x 1:CAS:528:DC%2BC3MXhtVKksrzL
    • Huttunen R, Syrjänen J, Vuento R, Hurme M, Huhtala H, Laine J, Pessi J, Aittoniemi J (2011) Plasma level of soluble urokinase-type plasminogen activator receptor as a predictor of disease severity and case fatality in patients with bacteraemia: a prospective cohort study. J Intern Med 270:32-40
    • (2011) J Intern Med , vol.270 , pp. 32-40
    • Huttunen, R.1    Syrjänen, J.2    Vuento, R.3    Hurme, M.4    Huhtala, H.5    Laine, J.6    Pessi, J.7    Aittoniemi, J.8
  • 19
    • 79951557734 scopus 로고    scopus 로고
    • Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients
    • 21324198 10.1186/cc10037
    • Koch A, Voigt S, Kruschinski C, Sanson E, Duckers H, Horn A, Yagmur E, Zimmermann H, Trautwein C, Tacke F (2011) Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients. Crit Care 15:R63
    • (2011) Crit Care , vol.15 , pp. 63
    • Koch, A.1    Voigt, S.2    Kruschinski, C.3    Sanson, E.4    Duckers, H.5    Horn, A.6    Yagmur, E.7    Zimmermann, H.8    Trautwein, C.9    Tacke, F.10
  • 22
    • 0038805215 scopus 로고    scopus 로고
    • Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury
    • 12730079 1:CAS:528:DC%2BD3sXls1Wmsb8%3D
    • Prabhakaran P, Ware LB, White KE, Cross MT, Matthay MA, Olman MA (2003) Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol 285:L20-L28
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285
    • Prabhakaran, P.1    Ware, L.B.2    White, K.E.3    Cross, M.T.4    Matthay, M.A.5    Olman, M.A.6
  • 23
    • 34547689307 scopus 로고    scopus 로고
    • Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome
    • National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network 17667242 10.1097/01.CCM.0000221922.08878.49
    • Ware LB, Matthay MA, Parsons PE, Thompson BT, Januzzi JL, Eisner MD, National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network (2007) Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome. Crit Care Med 35:1821-1828
    • (2007) Crit Care Med , vol.35 , pp. 1821-1828
    • Ware, L.B.1    Matthay, M.A.2    Parsons, P.E.3    Thompson, B.T.4    Januzzi, J.L.5    Eisner, M.D.6
  • 24
    • 76549118187 scopus 로고    scopus 로고
    • Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury
    • 19855955 10.1007/s00134-009-1690-2
    • Sapru A, Curley MA, Brady S, Matthay MA, Flori H (2010) Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. Intensive Care Med 36:157-163
    • (2010) Intensive Care Med , vol.36 , pp. 157-163
    • Sapru, A.1    Curley, M.A.2    Brady, S.3    Matthay, M.A.4    Flori, H.5
  • 25
    • 0024562002 scopus 로고
    • Promotion and subsequent inhibition of plasminogen activation after administration of intravenous endotoxin to normal subjects
    • 2496309 10.1056/NEJM198905043201802 1:CAS:528:DyaL1MXktVGitL8%3D
    • Suffredini AF, Harpel PC, Parrillo JE (1989) Promotion and subsequent inhibition of plasminogen activation after administration of intravenous endotoxin to normal subjects. N Engl J Med 320:1165-1172
    • (1989) N Engl J Med , vol.320 , pp. 1165-1172
    • Suffredini, A.F.1    Harpel, P.C.2    Parrillo, J.E.3
  • 26
    • 33845978751 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor 1 promotes a poor prognosis in sepsis-induced disseminated intravascular coagulation
    • 17189219 10.1532/IJH97.05190 1:CAS:528:DC%2BD2sXhsVSmsr4%3D
    • Madoiwa S, Nunomiya S, Ono T, Shintani Y, Ohmori T, Mimuro J, Sakata Y (2006) Plasminogen activator inhibitor 1 promotes a poor prognosis in sepsis-induced disseminated intravascular coagulation. Int J Hematol 84:398-405
    • (2006) Int J Hematol , vol.84 , pp. 398-405
    • Madoiwa, S.1    Nunomiya, S.2    Ono, T.3    Shintani, Y.4    Ohmori, T.5    Mimuro, J.6    Sakata, Y.7
  • 27
    • 36448962782 scopus 로고    scopus 로고
    • Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury
    • National Heart, Lung, and Blood Institute ARDS Network Clinical Trials Group 18074478 10.1097/01.CCM.0000291649.72238.6D
    • Liu KD, Glidden DV, Eisner MD, Parsons PE, Ware LB, Wheeler A, Korpak A, Thompson BT, Chertow GM, Matthay MA, National Heart, Lung, and Blood Institute ARDS Network Clinical Trials Group (2007) Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury. Crit Care Med 35:2755-2756
    • (2007) Crit Care Med , vol.35 , pp. 2755-2756
    • Liu, K.D.1    Glidden, D.V.2    Eisner, M.D.3    Parsons, P.E.4    Ware, L.B.5    Wheeler, A.6    Korpak, A.7    Thompson, B.T.8    Chertow, G.M.9    Matthay, M.A.10
  • 28
    • 78751646073 scopus 로고    scopus 로고
    • Plasminogen activation inhibitor concentrations in bronchoalveolar lavage fluid distinguishes ventilator-associated pneumonia from colonization in mechanically ventilated pediatric patients
    • 20473240 10.1097/PCC.0b013e3181e2a352
    • Srinivasan R, Song Y, Wiener-Kronish J, Flori HR (2011) Plasminogen activation inhibitor concentrations in bronchoalveolar lavage fluid distinguishes ventilator-associated pneumonia from colonization in mechanically ventilated pediatric patients. Pediatr Crit Care Med 12:21-27
    • (2011) Pediatr Crit Care Med , vol.12 , pp. 21-27
    • Srinivasan, R.1    Song, Y.2    Wiener-Kronish, J.3    Flori, H.R.4
  • 31
    • 34247328556 scopus 로고    scopus 로고
    • Use of plasma C-reactive protein, procalcitonin, neutrophils, macrophage migration inhibitory factor, soluble urokinase-type plasminogen activator receptor, and soluble triggering receptor expressed on myeloid cells-1 in combination to diagnose infections: A prospective study
    • 17362525 10.1186/cc5723
    • Kofoed K, Andersen O, Kronborg G, Tvede M, Petersen J, Eugen-Olsen J, Larsen K (2007) Use of plasma C-reactive protein, procalcitonin, neutrophils, macrophage migration inhibitory factor, soluble urokinase-type plasminogen activator receptor, and soluble triggering receptor expressed on myeloid cells-1 in combination to diagnose infections: a prospective study. Crit Care 11:R38
    • (2007) Crit Care , vol.11 , pp. 38
    • Kofoed, K.1    Andersen, O.2    Kronborg, G.3    Tvede, M.4    Petersen, J.5    Eugen-Olsen, J.6    Larsen, K.7
  • 32
    • 77956561594 scopus 로고    scopus 로고
    • Selective abrogation of the uPA-uPAR interaction in vivo reveals a novel role in suppression of fibrin-associated inflammation
    • 20466854 10.1182/blood-2010-03-276642 1:CAS:528:DC%2BC3cXhtF2qsb3N
    • Connolly BM, Choi EY, Gårdsvoll H, Bey AL, Currie BM, Chavakis T, Liu S, Molinolo A, Ploug M, Leppla SH, Bugge TH (2010) Selective abrogation of the uPA-uPAR interaction in vivo reveals a novel role in suppression of fibrin-associated inflammation. Blood 116:1593-1603
    • (2010) Blood , vol.116 , pp. 1593-1603
    • Connolly, B.M.1    Choi, E.Y.2    Gårdsvoll, H.3    Bey, A.L.4    Currie, B.M.5    Chavakis, T.6    Liu, S.7    Molinolo, A.8    Ploug, M.9    Leppla, S.H.10    Bugge, T.H.11
  • 33
    • 0035715545 scopus 로고    scopus 로고
    • Soluble urokinase plasminogen activator receptor measurements: Influence of sample handling
    • 11820717 1:CAS:528:DC%2BD38XjtFChsrY%3D
    • Riisbro R, Christensen IJ, Høgdall C, Brünner N, Høgdall E (2001) Soluble urokinase plasminogen activator receptor measurements: influence of sample handling. Int J Biol Markers 16:233-239
    • (2001) Int J Biol Markers , vol.16 , pp. 233-239
    • Riisbro, R.1    Christensen, I.J.2    Høgdall, C.3    Brünner, N.4    Høgdall, E.5
  • 34
  • 35
    • 33751114649 scopus 로고    scopus 로고
    • A randomized controlled clinical trial to evaluate the efficacy, safety, cost-effectiveness and effect on PAI-1 levels of the three low-molecular-weight- heparins-enoxaparin nadroparin and dalteparin. The escape-end study
    • 17057417 10.1159/000096484 1:CAS:528:DC%2BD28Xht1SrtLnM
    • Shafiq N, Malhotra S, Pandhi P, Sharma N, Bhalla A, Grover A (2006) A randomized controlled clinical trial to evaluate the efficacy, safety, cost-effectiveness and effect on PAI-1 levels of the three low-molecular-weight- heparins-enoxaparin nadroparin and dalteparin. The escape-end study. Pharmacology 78:136-143
    • (2006) Pharmacology , vol.78 , pp. 136-143
    • Shafiq, N.1    Malhotra, S.2    Pandhi, P.3    Sharma, N.4    Bhalla, A.5    Grover, A.6


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