Effect of taurine and N-acetylcysteine on methionine restriction-mediated adiposity resistance

Metabolism: Clinical and Experimental

Volumn 62, Issue 4, 2013, Pages 509-517

  Elshorbagy, Amany K ^a,b   Valdivia Garcia, Maria ^a   Mattocks, Dwight A L ^c   Plummer, Jason D ^c   Orentreich, David S ^c   Orentreich, Norman ^c   Refsum, Helga ^a,d   Perrone, Carmen E ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ALEXANDRIA UNIVERSITY   (Egypt)

^c Orentreich Foundation for the Advancement of Science Inc   (United States)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

Cysteine; Fatty acid profile; Glutathione; Stearoyl coenzyme A desaturase; Sulfur amino acids

Indexed keywords

ACETYLCYSTEINE; FATTY ACID; LEPTIN; METHIONINE; SULFUR AMINO ACID; TAURINE; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FAT; CONTROLLED STUDY; FATTY ACID ANALYSIS; FATTY ACID BLOOD LEVEL; GENE EXPRESSION; HYPERTRIGLYCERIDEMIA; LIVER; MALE; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN; WHITE ADIPOSE TISSUE;

ACETYLCYSTEINE; ADIPOSITY; AMINO ACIDS; AMINO ACIDS, SULFUR; ANIMALS; CYSTEINE; DIET; FATTY ACIDS, NONESTERIFIED; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIPIDS; MALE; METHIONINE; RATS; RATS, INBRED F344; STEAROYL-COA DESATURASE; TAURINE; WEIGHT GAIN;

EID: 84884212781     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2012.10.005     Document Type: Article

References (49)

1. N. Orentreich, J.R. Matias, and A. DeFelice Low methionine ingestion by rats extends life span J Nutr 123 2 1993 269 274
2. V.L. Malloy, R.A. Krajcik, and S.J. Bailey Methionine restriction decreases visceral fat mass and preserves insulin action in aging male Fischer 344 rats independent of energy restriction Aging Cell 5 4 2006 305 314
3. B.E. Hasek, L.K. Stewart, and T.M. Henagan Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states Am J Physiol Regul Integr Comp Physiol 299 3 2010 R728 R739
4. L.K. Heilbronn, and E. Ravussin Calorie restriction and aging: review of the literature and implications for studies in humans Am J Clin Nutr 78 3 2003 361 369
5. E.P. Plaisance, T.M. Henagan, and H. Echlin Role of beta-adrenergic receptors in the hyperphagic and hypermetabolic responses to dietary methionine restriction Am J Physiol Regul Integr Comp Physiol 299 3 2010 R740 R750
6. Y. Cheng, Q. Meng, and C. Wang Leucine deprivation decreases fat mass by stimulation of lipolysis in white adipose tissue and upregulation of uncoupling protein 1 (UCP1) in brown adipose tissue Diabetes 59 1 2010 17 25
7. M.J. Toth, and E.T. Poehlman Sympathetic nervous system activity and resting metabolic rate in vegetarians Metabolism 43 5 1994 621 625
8. M. Rosell, P. Appleby, and E. Spencer Weight gain over 5 years in 21,966 meat-eating, fish-eating, vegetarian, and vegan men and women in EPIC-Oxford Int J Obes (Lond) 30 9 2006 1389 1396
9. G.M. Turner-McGrievy, N.D. Barnard, and A.R. Scialli A two-year randomized weight loss trial comparing a vegan diet to a more moderate low-fat diet Obesity (Silver Spring) 15 9 2007 2276 2281
10. A.K. Elshorbagy, M. Valdivia-Garcia, and H. Refsum Sulfur amino acids in methionine-restricted rats: hyperhomocysteinemia Nutrition 26 11-12 2010 1201 1204
11. A.K. Elshorbagy, E. Nurk, and C.G. Gjesdal Homocysteine, cysteine, and body composition in the Hordaland Homocysteine Study: does cysteine link amino acid and lipid metabolism? Am J Clin Nutr 88 3 2008 738 746
12. A.K. Elshorbagy, M. Valdivia-Garcia, and D.A. Mattocks Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase J Lipid Res 52 1 2011 104 112
13. G. Rizki, L. Arnaboldi, and B. Gabrielli Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1 J Lipid Res 47 10 2006 2280 2290
14. C.E. Perrone, D.A. Mattocks, and M. Jarvis-Morar Methionine restriction effects on mitochondrial biogenesis and aerobic capacity in white adipose tissue, liver, and skeletal muscle of F344 rats Metabolism 59 7 2010 1000 1011
15. A.K. Elshorbagy, M. Valdivia-Garcia, and I.M. Graham The association of fasting plasma sulfur-containing compounds with BMI, serum lipids and apolipoproteins Nutr Metab Cardiovasc Dis 2011 http://dx.doi.org/S0939-4753(11) 00024-X [pii] 10.1016/j.numecd.2011.01.008 (In press)
16. T.R. Nardelli, R.A. Ribeiro, and S.L. Balbo Taurine prevents fat deposition and ameliorates plasma lipid profile in monosodium glutamate-obese rats Amino Acids 41 4 2011 901 908
17. N. Tsuboyama-Kasaoka, C. Shozawa, and K. Sano Taurine (2-aminoethanesulfonic acid) deficiency creates a vicious circle promoting obesity Endocrinology 147 7 2006 3276 3284
18. K. Hultman, C. Alexanderson, and L. Manneras Maternal taurine supplementation in the late pregnant rat stimulates postnatal growth and induces obesity and insulin resistance in adult offspring J Physiol 579 Pt 3 2007 823 833
19. C.S. Solon, D. Franci, and L.M. Ignacio-Souza Taurine enhances the anorexigenic effects of insulin in the hypothalamus of rats Amino Acids 42 6 2012 2403 2410
20. W. Hildebrandt, A. Hamann, and H. Krakowski-Roosen Effect of thiol antioxidant on body fat and insulin reactivity J Mol Med 82 5 2004 336 344
21. J.R. Kim, H.H. Ryu, and H.J. Chung Association of anti-obesity activity of N-acetylcysteine with metallothionein-II down-regulation Exp Mol Med 38 2 2006 162 172
22. E.L. Novelli, P.P. Santos, and H.B. Assalin N-acetylcysteine in high-sucrose diet-induced obesity: energy expenditure and metabolic shifting for cardiac health Pharmacol Res 59 1 2009 74 79
23. C. Antoniades, C. Shirodaria, and P. Leeson MTHFR 677 C>T polymorphism reveals functional importance for 5-mthyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis Circulation 119 18 2009 2507 2515
24. K.J. Vinknes, A.K. Elshorbagy, and E. Nurk Plasma stearoyl-CoA desaturase indices: association with lifestyle, diet and body composition Obesity (Silver Spring) 2012 In press
25. A. Peter, A. Cegan, and S. Wagner Hepatic lipid composition and stearoyl-coenzyme A desaturase 1 mRNA expression can be estimated from plasma VLDL fatty acid ratios Clin Chem 55 12 2009 2113 2120
26. H. Yokogoshi, and H. Oda Dietary taurine enhances cholesterol degradation and reduces serum and liver cholesterol concentrations in rats fed a high-cholesterol diet Amino Acids 23 4 2002 433 439
27. M.J. Choi, and K.J. Chang The effects of dietary taurine supplementation on plasma and liver lipid in ovariectomized rats Adv Exp Med Biol 643 2009 389 395
28. M.T. Flowers, and J.M. Ntambi Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism Curr Opin Lipidol 19 3 2008 248 256
29. E. Fujihira, H. Takahashi, and M. Nakazawa Effect of long-term feeding of taurine in hereditary hyperglycemic obese mice Chem Pharm Bull(Tokyo) 18 8 1970 1636 1642
30. G. Pina-Zentella, G. delaRosa-Cuevas, and H. Vazquez-Meza Taurine in adipocytes prevents insulin-mediated H2O2 generation and activates Pka and lipolysis Amino Acids 42 5 2012 1927 1935
31. C.E. Perrone, D.A. Mattocks, and G. Hristopoulos Methionine restriction effects on 11β-HSD1 activity and lipogenic/lipolytic balance in F344 rat adipose tissue J Lipid Res 49 1 2008 12 23
32. S.H. Cheong, C.H. Yu, and M.J. Choi Effects of garlic powder and taurine supplementation on abdominal fat, muscle weight, and blood amino acid pattern in ovariectomized rats Adv Exp Med Biol 583 2006 221 226
33. S. Murakami, Y. Kondo, and T. Nagate Effects of long-term treatment with taurine in mice fed a high-fat diet: improvement in cholesterol metabolism and vascular lipid accumulation by taurine Adv Exp Med Biol 483 2000 177 186
34. K.R. Atkuri, J.J. Mantovani, and L.A. Herzenberg N-Acetylcysteine - a safe antidote for cysteine/glutathione deficiency Curr Opin Pharmacol 7 4 2007 355 359
35. B. Ates, L. Abraham, and N. Ercal Antioxidant and free radical scavenging properties of N-acetylcysteine amide (NACA) and comparison with N-acetylcysteine (NAC) Free Radic Res 42 4 2008 372 377
36. B. Hultberg, A. Andersson, and P. Masson Plasma homocysteine and thiol compound fractions after oral administration of N-acetylcysteine Scand J Clin Lab Invest 54 6 1994 417 422
37. P. Ventura, R. Panini, and G. Abbati Urinary and plasma homocysteine and cysteine levels during prolonged oral N-acetylcysteine therapy Pharmacology 68 2 2003 105 114
38. K.N. Maclean, J. Sikora, and V. Kozich Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment Mol Genet Metab 101 2-3 2010 163 171
39. O. Wiklund, G. Fager, and A. Andersson N-acetylcysteine treatment lowers plasma homocysteine but not serum lipoprotein(a) levels Atherosclerosis 119 1 1996 99 106
40. S. Doshi, I. McDowell, and J. Goodfellow Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia Metabolism 54 3 2005 351 360
41. C.C. Lin, and M.C. Yin Effects of cysteine-containing compounds on biosynthesis of triacylglycerol and cholesterol and anti-oxidative protection in liver from mice consuming a high-fat diet Br J Nutr 99 1 2008 37 43
42. G. Muller, S. Wied, and S. Over Inhibition of lipolysis by palmitate, H2O2 and the sulfonylurea drug, glimepiride, in rat adipocytes depends on cAMP degradation by lipid droplets Biochemistry (Mosc) 47 5 2008 1259 1273
43. M.Z. de Pina, H. Vazquez-Meza, and J.P. Pardo Signaling the signal, cyclic AMP-dependent protein kinase inhibition by insulin-formed H2O2 and reactivation by thioredoxin J Biol Chem 283 18 2008 12373 12386
44. S. Furukawa, T. Fujita, and M. Shimabukuro Increased oxidative stress in obesity and its impact on metabolic syndrome J Clin Invest 114 12 2004 1752 1761
45. T. Wang, Y. Si, and O.S. Shirihai Respiration in adipocytes is inhibited by reactive oxygen species Obesity (Silver Spring) 18 8 2010 1493 1502
46. P. Calzadilla, D. Sapochnik, and S. Cosentino N-acetylcysteine reduces markers of differentiation in 3T3-L1 adipocytes Int J Mol Sci 12 10 2011 6936 6951
47. M.W. Lieberman, A.L. Wiseman, and Z.Z. Shi Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice Proc Natl Acad Sci USA 93 15 1996 7923 7926
48. S. Gupta, and W.D. Kruger Cystathionine beta-synthase deficiency causes fat loss in mice PLoS One 6 11 2011 e27598
49. A.K. Elshorbagy, A.D. Smith, and V. Kozich Cysteine and obesity Obesity (Silver Spring) 20 3 2012 473 481