-
1
-
-
0035215395
-
Proteasome inhibition in cancer: Development of PS-341
-
Adams J. Proteasome inhibition in cancer: Development of PS-341. Semin Oncol 2001, 28:613-619.
-
(2001)
Semin Oncol
, vol.28
, pp. 613-619
-
-
Adams, J.1
-
2
-
-
0035300479
-
The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
-
Hideshima T., Richardson P., Chauhan D., et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 2001, 61:3071-3076.
-
(2001)
Cancer Res
, vol.61
, pp. 3071-3076
-
-
Hideshima, T.1
Richardson, P.2
Chauhan, D.3
-
3
-
-
0242496212
-
Molecular sequelae of proteasome inhibition in human multiple myeloma cells
-
Mitsiades N., Mitsiades C.S., Poulaki V., et al. Molecular sequelae of proteasome inhibition in human multiple myeloma cells. Proc Natl Acad Sci USA 2002, 99:14374-14379.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14374-14379
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
-
4
-
-
0033615348
-
The proteasome: A macromolecular assembly designed for controlled proteolysis
-
Zwickl P., Voges D., Baumeister W. The proteasome: A macromolecular assembly designed for controlled proteolysis. Philos Trans R Soc Lond B Biol Sci 1999, 354:1501-1511.
-
(1999)
Philos Trans R Soc Lond B Biol Sci
, vol.354
, pp. 1501-1511
-
-
Zwickl, P.1
Voges, D.2
Baumeister, W.3
-
5
-
-
0029874138
-
The NF-kappa B and I kappa B proteins: New discoveries and insights
-
Baldwin A.S. The NF-kappa B and I kappa B proteins: New discoveries and insights. Annu Rev Immunol 1996, 14:649-683.
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 649-683
-
-
Baldwin, A.S.1
-
6
-
-
0142054051
-
Bortezomib (PS-341): A novel, first-in-class proteasome inhibitor for the treatment of multiple myeloma and other cancers
-
Richardson P.G., Hideshima T., Anderson K.C. Bortezomib (PS-341): A novel, first-in-class proteasome inhibitor for the treatment of multiple myeloma and other cancers. Cancer Control 2003, 10:361-369.
-
(2003)
Cancer Control
, vol.10
, pp. 361-369
-
-
Richardson, P.G.1
Hideshima, T.2
Anderson, K.C.3
-
7
-
-
0032885434
-
Constitutive activation of transcription factors NF-(kappa)B, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines
-
Ondrey F.G., Dong G., Sunwoo J., et al. Constitutive activation of transcription factors NF-(kappa)B, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines. Mol Carcinog 1999, 26:119-129.
-
(1999)
Mol Carcinog
, vol.26
, pp. 119-129
-
-
Ondrey, F.G.1
Dong, G.2
Sunwoo, J.3
-
8
-
-
0035207110
-
The role of nuclear factor-kappaB in the biology and treatment of multiple myeloma
-
Berenson J.R., Ma H.M., Vescio R. The role of nuclear factor-kappaB in the biology and treatment of multiple myeloma. Semin Oncol 2001, 28:626-633.
-
(2001)
Semin Oncol
, vol.28
, pp. 626-633
-
-
Berenson, J.R.1
Ma, H.M.2
Vescio, R.3
-
9
-
-
18544367201
-
NF-kappa B as a therapeutic target in multiple myeloma
-
Hideshima T., Chauhan D., Richardson P., et al. NF-kappa B as a therapeutic target in multiple myeloma. JBiol Chem 2002, 277:16639-16647.
-
(2002)
JBiol Chem
, vol.277
, pp. 16639-16647
-
-
Hideshima, T.1
Chauhan, D.2
Richardson, P.3
-
10
-
-
0031985626
-
Role of proteasomes in T cell activation and proliferation
-
Wang X., Luo H., Chen H., et al. Role of proteasomes in T cell activation and proliferation. JImmunol 1998, 160:788-801.
-
(1998)
JImmunol
, vol.160
, pp. 788-801
-
-
Wang, X.1
Luo, H.2
Chen, H.3
-
11
-
-
0036870323
-
On the role of proteasomes in cell biology and proteasome inhibition as a novel frontier in the development of immunosuppressants
-
Wu J. On the role of proteasomes in cell biology and proteasome inhibition as a novel frontier in the development of immunosuppressants. Am J Transplant 2002, 2:904-912.
-
(2002)
Am J Transplant
, vol.2
, pp. 904-912
-
-
Wu, J.1
-
12
-
-
0037008780
-
Evidence that inhibition of p44/42 mitogen-activated protein kinase signaling is a factor in proteasome inhibitor-mediated apoptosis
-
Orlowski R.Z., Small G.W., Shi Y.Y. Evidence that inhibition of p44/42 mitogen-activated protein kinase signaling is a factor in proteasome inhibitor-mediated apoptosis. JBiol Chem 2002, 277:27864-27871.
-
(2002)
JBiol Chem
, vol.277
, pp. 27864-27871
-
-
Orlowski, R.Z.1
Small, G.W.2
Shi, Y.Y.3
-
13
-
-
0035958517
-
The role of tumor necrosis factor alpha in the pathophysiology of human multiple myeloma: Therapeutic applications
-
Hideshima T., Chauhan D., Schlossman R., et al. The role of tumor necrosis factor alpha in the pathophysiology of human multiple myeloma: Therapeutic applications. Oncogene 2001, 20:4519-4527.
-
(2001)
Oncogene
, vol.20
, pp. 4519-4527
-
-
Hideshima, T.1
Chauhan, D.2
Schlossman, R.3
-
14
-
-
0034902354
-
Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma
-
Sunwoo J.B., Chen Z., Dong G., et al. Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. Clin Cancer Res 2001, 7:1419-1428.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1419-1428
-
-
Sunwoo, J.B.1
Chen, Z.2
Dong, G.3
-
15
-
-
0031895637
-
Mechanisms of MHC class I-restricted antigen processing
-
Pamer E., Cresswell P. Mechanisms of MHC class I-restricted antigen processing. Annu Rev Immunol 1998, 16:323-358.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 323-358
-
-
Pamer, E.1
Cresswell, P.2
-
16
-
-
0032971227
-
Degradation of cell proteins and the generation of MHC class I-presented peptides
-
Rock K.L., Goldberg A.L. Degradation of cell proteins and the generation of MHC class I-presented peptides. Annu Rev Immunol 1999, 17:739-779.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 739-779
-
-
Rock, K.L.1
Goldberg, A.L.2
-
18
-
-
33845520806
-
Proteasome inhibitors: Antitumor effects and beyond
-
Nencioni A., Grunebach F., Patrone F., et al. Proteasome inhibitors: Antitumor effects and beyond. Leukemia 2007, 21:30-36.
-
(2007)
Leukemia
, vol.21
, pp. 30-36
-
-
Nencioni, A.1
Grunebach, F.2
Patrone, F.3
-
19
-
-
0035889230
-
Inhibition of NF-kappaB-dependent T cell activation abrogates acute allograft rejection
-
Finn P.W., Stone J.R., Boothby M.R., Perkins D.L. Inhibition of NF-kappaB-dependent T cell activation abrogates acute allograft rejection. JImmunol 2001, 167:5994-6001.
-
(2001)
JImmunol
, vol.167
, pp. 5994-6001
-
-
Finn, P.W.1
Stone, J.R.2
Boothby, M.R.3
Perkins, D.L.4
-
20
-
-
43749098729
-
Proteasome inhibition suppresses essential immune functions of human CD4+ T cells
-
Berges C., Haberstock H., Fuchs D., et al. Proteasome inhibition suppresses essential immune functions of human CD4+ T cells. Immunology 2008, 124:234-246.
-
(2008)
Immunology
, vol.124
, pp. 234-246
-
-
Berges, C.1
Haberstock, H.2
Fuchs, D.3
-
21
-
-
33646421393
-
Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines
-
Blanco B., Perez-Simon J.A., Sanchez-Abarca L.I., et al. Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines. Blood 2006, 107:3575-3583.
-
(2006)
Blood
, vol.107
, pp. 3575-3583
-
-
Blanco, B.1
Perez-Simon, J.A.2
Sanchez-Abarca, L.I.3
-
22
-
-
67650767034
-
Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T cell population
-
Blanco B., Perez-Simon J.A., Sanchez-Abarca L.I., et al. Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T cell population. Haematologica 2009, 94:975-983.
-
(2009)
Haematologica
, vol.94
, pp. 975-983
-
-
Blanco, B.1
Perez-Simon, J.A.2
Sanchez-Abarca, L.I.3
-
23
-
-
2542599273
-
Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib
-
Sun K., Welniak L.A., Panoskaltsis-Mortari A., et al. Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib. Proc Natl Acad Sci USA 2004, 101:8120-8125.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 8120-8125
-
-
Sun, K.1
Welniak, L.A.2
Panoskaltsis-Mortari, A.3
-
24
-
-
30444458109
-
NF-kappaB as a target for the prevention of graft-versus-host disease: Comparative efficacy of bortezomib and PS-1145
-
Vodanovic-Jankovic S., Hari P., Jacobs P., et al. NF-kappaB as a target for the prevention of graft-versus-host disease: Comparative efficacy of bortezomib and PS-1145. Blood 2006, 107:827-834.
-
(2006)
Blood
, vol.107
, pp. 827-834
-
-
Vodanovic-Jankovic, S.1
Hari, P.2
Jacobs, P.3
-
25
-
-
27644477944
-
Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): Delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity
-
Sun K., Wilkins D.E., Anver M.R., et al. Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): Delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity. Blood 2005, 106:3293-3299.
-
(2005)
Blood
, vol.106
, pp. 3293-3299
-
-
Sun, K.1
Wilkins, D.E.2
Anver, M.R.3
-
26
-
-
36348990198
-
Use of bortezomib in the management of chronic graft-versus-host disease among multiple myeloma patients relapsing after allogeneic transplantation
-
Mateos-Mazon J., Perez-Simon J.A., Lopez O., et al. Use of bortezomib in the management of chronic graft-versus-host disease among multiple myeloma patients relapsing after allogeneic transplantation. Haematologica 2007, 92:1295-1296.
-
(2007)
Haematologica
, vol.92
, pp. 1295-1296
-
-
Mateos-Mazon, J.1
Perez-Simon, J.A.2
Lopez, O.3
-
27
-
-
0032587384
-
Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor
-
Wang X.C., Jobin C., Allen J.B., et al. Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor. Invest Ophthalmol Vis Sci 1999, 40:477-486.
-
(1999)
Invest Ophthalmol Vis Sci
, vol.40
, pp. 477-486
-
-
Wang, X.C.1
Jobin, C.2
Allen, J.B.3
-
28
-
-
40849096556
-
High response rate and improved graft-versus-host disease following bortezomib as salvage therapy after reduced intensity conditioning allogeneic stem cell transplantation for multiple myeloma
-
El-Cheikh J., Michallet M., Nagler A., et al. High response rate and improved graft-versus-host disease following bortezomib as salvage therapy after reduced intensity conditioning allogeneic stem cell transplantation for multiple myeloma. Haematologica 2008, 93:455-458.
-
(2008)
Haematologica
, vol.93
, pp. 455-458
-
-
El-Cheikh, J.1
Michallet, M.2
Nagler, A.3
-
29
-
-
70449723162
-
Bortezomib, tacrolimus, and methotrexate for prophylaxis of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation from HLA-mismatched unrelated donors
-
Koreth J., Stevenson K.E., Kim H.T., et al. Bortezomib, tacrolimus, and methotrexate for prophylaxis of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation from HLA-mismatched unrelated donors. Blood 2009, 114:3956-3959.
-
(2009)
Blood
, vol.114
, pp. 3956-3959
-
-
Koreth, J.1
Stevenson, K.E.2
Kim, H.T.3
-
30
-
-
84866546465
-
Bortezomib-based graft-versus-host disease prophylaxis in HLA-mismatched unrelated donor transplantation
-
Koreth J., Stevenson K.E., Kim H.T., et al. Bortezomib-based graft-versus-host disease prophylaxis in HLA-mismatched unrelated donor transplantation. JClin Oncol 2012, 30:3202-3208.
-
(2012)
JClin Oncol
, vol.30
, pp. 3202-3208
-
-
Koreth, J.1
Stevenson, K.E.2
Kim, H.T.3
-
31
-
-
75749083746
-
Deciphering antibody-mediated rejection: New insights into mechanisms and treatment
-
Stegall M.D., Gloor J.M. Deciphering antibody-mediated rejection: New insights into mechanisms and treatment. Curr Opin Organ Transplant 2010, 15:8-10.
-
(2010)
Curr Opin Organ Transplant
, vol.15
, pp. 8-10
-
-
Stegall, M.D.1
Gloor, J.M.2
-
32
-
-
77957734604
-
Rejection of the kidney allograft
-
Nankivell B.J., Alexander S.I. Rejection of the kidney allograft. NEngl J Med 2010, 363:1451-1462.
-
(2010)
NEngl J Med
, vol.363
, pp. 1451-1462
-
-
Nankivell, B.J.1
Alexander, S.I.2
-
33
-
-
58049200722
-
Proteasome inhibition causes apoptosis of normal human plasma cells preventing alloantibody production
-
Perry D.K., Burns J.M., Pollinger H.S., et al. Proteasome inhibition causes apoptosis of normal human plasma cells preventing alloantibody production. Am J Transplant 2009, 9:201-209.
-
(2009)
Am J Transplant
, vol.9
, pp. 201-209
-
-
Perry, D.K.1
Burns, J.M.2
Pollinger, H.S.3
-
34
-
-
58849136282
-
Bortezomib provides effective therapy for antibody- and cell-mediated acute rejection
-
Everly M.J., Everly J.J., Susskind B., et al. Bortezomib provides effective therapy for antibody- and cell-mediated acute rejection. Transplantation 2008, 86:1754-1761.
-
(2008)
Transplantation
, vol.86
, pp. 1754-1761
-
-
Everly, M.J.1
Everly, J.J.2
Susskind, B.3
-
35
-
-
76649086359
-
Proteasome inhibitor-based primary therapy for antibody-mediated renal allograft rejection
-
Walsh R.C., Everly J.J., Brailey P., et al. Proteasome inhibitor-based primary therapy for antibody-mediated renal allograft rejection. Transplantation 2010, 89:277-284.
-
(2010)
Transplantation
, vol.89
, pp. 277-284
-
-
Walsh, R.C.1
Everly, J.J.2
Brailey, P.3
-
36
-
-
78650840827
-
The role of proteasome inhibition with bortezomib in the treatment of antibody-mediated rejection after kidney-only or kidney-combined organ transplantation
-
Flechner S.M., Fatica R., Askar M., et al. The role of proteasome inhibition with bortezomib in the treatment of antibody-mediated rejection after kidney-only or kidney-combined organ transplantation. Transplantation 2010, 90:1486-1492.
-
(2010)
Transplantation
, vol.90
, pp. 1486-1492
-
-
Flechner, S.M.1
Fatica, R.2
Askar, M.3
-
37
-
-
68049119098
-
Elimination of post-transplant donor-specific HLA antibodies with bortezomib
-
Idica A., Kaneku H., Everly M.J., et al. Elimination of post-transplant donor-specific HLA antibodies with bortezomib. Clin Transplant 2008, 229-239.
-
(2008)
Clin Transplant
, pp. 229-239
-
-
Idica, A.1
Kaneku, H.2
Everly, M.J.3
-
38
-
-
67649586605
-
Abrogation of anti-HLA antibodies via proteasome inhibition
-
Trivedi H.L., Terasaki P.I., Feroz A., et al. Abrogation of anti-HLA antibodies via proteasome inhibition. Transplantation 2009, 87:1555-1561.
-
(2009)
Transplantation
, vol.87
, pp. 1555-1561
-
-
Trivedi, H.L.1
Terasaki, P.I.2
Feroz, A.3
-
39
-
-
60649114718
-
Proteasome inhibition reduces donor-specific antibody levels
-
Everly M.J., Everly J.J., Susskind B., et al. Proteasome inhibition reduces donor-specific antibody levels. Transplant Proc 2009, 41:105-107.
-
(2009)
Transplant Proc
, vol.41
, pp. 105-107
-
-
Everly, M.J.1
Everly, J.J.2
Susskind, B.3
-
40
-
-
77954583919
-
Bortezomib for acute humoral rejection in two repeat transplant recipients
-
Hardinger K.L., Alford K., Murillo D. Bortezomib for acute humoral rejection in two repeat transplant recipients. Clin Transplant 2009, 479-483.
-
(2009)
Clin Transplant
, pp. 479-483
-
-
Hardinger, K.L.1
Alford, K.2
Murillo, D.3
-
41
-
-
77954617224
-
Antihumoral rejection therapy by proteasome inhibitor bortezomib: A case series
-
Lachmann N., Schutz M., Budde K., et al. Antihumoral rejection therapy by proteasome inhibitor bortezomib: A case series. Clin Transplant 2009, 351-358.
-
(2009)
Clin Transplant
, pp. 351-358
-
-
Lachmann, N.1
Schutz, M.2
Budde, K.3
-
42
-
-
77954616402
-
Bortezomib in the treatment of antibody-mediated rejection-a report of 3 cases
-
Mai H.L., Cesbron A., Brouard S., et al. Bortezomib in the treatment of antibody-mediated rejection-a report of 3 cases. Clin Transplant 2009, 361-368.
-
(2009)
Clin Transplant
, pp. 361-368
-
-
Mai, H.L.1
Cesbron, A.2
Brouard, S.3
-
43
-
-
77954595639
-
Use of bortezomib for treatment of antibody medicated rejection in kidney transplant recipients-case report
-
Hamawi K., Heilman R.L., Mazur M.J., et al. Use of bortezomib for treatment of antibody medicated rejection in kidney transplant recipients-case report. Clin Transplant 2009, 407-414.
-
(2009)
Clin Transplant
, pp. 407-414
-
-
Hamawi, K.1
Heilman, R.L.2
Mazur, M.J.3
-
44
-
-
76949099011
-
Bortezomib as the sole post-renal transplantation desensitization agent does not decrease donor-specific anti-HLA antibodies
-
Sberro-Soussan R., Zuber J., Suberbielle-Boissel C., et al. Bortezomib as the sole post-renal transplantation desensitization agent does not decrease donor-specific anti-HLA antibodies. Am J Transplant 2010, 10:681-686.
-
(2010)
Am J Transplant
, vol.10
, pp. 681-686
-
-
Sberro-Soussan, R.1
Zuber, J.2
Suberbielle-Boissel, C.3
-
45
-
-
77954575639
-
Bortezomib in kidney transplant recipients with antibody mediated rejection: Three case reports
-
Wong W., Lee R.A., Saidman S.L., et al. Bortezomib in kidney transplant recipients with antibody mediated rejection: Three case reports. Clin Transplant 2009, 401-405.
-
(2009)
Clin Transplant
, pp. 401-405
-
-
Wong, W.1
Lee, R.A.2
Saidman, S.L.3
-
46
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett F.C., Edworthy S.M., Bloch D.A., et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988, 31:315-324.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
-
47
-
-
0034079894
-
Current treatment paradigms in rheumatoid arthritis
-
Fries J.F. Current treatment paradigms in rheumatoid arthritis. Rheumatology (Oxford) 2000, 39(Suppl 1):30-35.
-
(2000)
Rheumatology (Oxford)
, vol.39
, Issue.SUPPL 1
, pp. 30-35
-
-
Fries, J.F.1
-
48
-
-
33747795644
-
Progression of radiographic joint damage in different eras: Trends towards milder disease in rheumatoid arthritis are attributable to improved treatment
-
Finckh A., Choi H.K., Wolfe F. Progression of radiographic joint damage in different eras: Trends towards milder disease in rheumatoid arthritis are attributable to improved treatment. Ann Rheum Dis 2006, 65:1192-1197.
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 1192-1197
-
-
Finckh, A.1
Choi, H.K.2
Wolfe, F.3
-
49
-
-
77649107244
-
Discussion: DMARDs and biologic therapies in the management of inflammatory joint diseases
-
Vaz A., Lisse J., Rizzo W., Albani S. Discussion: DMARDs and biologic therapies in the management of inflammatory joint diseases. Expert Rev Clin Immunol 2009, 5:291-299.
-
(2009)
Expert Rev Clin Immunol
, vol.5
, pp. 291-299
-
-
Vaz, A.1
Lisse, J.2
Rizzo, W.3
Albani, S.4
-
51
-
-
79955040826
-
New therapies in the management of rheumatoid arthritis
-
Buch M.H., Emery P. New therapies in the management of rheumatoid arthritis. Curr Opin Rheumatol 2011, 23:245-251.
-
(2011)
Curr Opin Rheumatol
, vol.23
, pp. 245-251
-
-
Buch, M.H.1
Emery, P.2
-
52
-
-
0033144367
-
Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis
-
Jue D.M., Jeon K.I., Jeong J.Y. Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis. JKorean Med Sci 1999, 14:231-238.
-
(1999)
JKorean Med Sci
, vol.14
, pp. 231-238
-
-
Jue, D.M.1
Jeon, K.I.2
Jeong, J.Y.3
-
54
-
-
0036729083
-
Interleukin 1 or tumor necrosis factor-alpha: Which is the real target in rheumatoid arthritis?
-
Dayer J.M. Interleukin 1 or tumor necrosis factor-alpha: Which is the real target in rheumatoid arthritis?. JRheumatol Suppl 2002, 65:10-15.
-
(2002)
JRheumatol Suppl
, vol.65
, pp. 10-15
-
-
Dayer, J.M.1
-
55
-
-
54049112718
-
Targeting NF-kappaB: A promising molecular therapy in inflammatory arthritis
-
Roman-Blas J.A., Jimenez S.A. Targeting NF-kappaB: A promising molecular therapy in inflammatory arthritis. Int Rev Immunol 2008, 27:351-374.
-
(2008)
Int Rev Immunol
, vol.27
, pp. 351-374
-
-
Roman-Blas, J.A.1
Jimenez, S.A.2
-
56
-
-
78049497262
-
The proteasome inhibitor bortezomib drastically affects inflammation and bone disease in adjuvant-induced arthritis in rats
-
Yannaki E., Papadopoulou A., Athanasiou E., et al. The proteasome inhibitor bortezomib drastically affects inflammation and bone disease in adjuvant-induced arthritis in rats. Arthritis Rheum 2010, 62:3277-3288.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 3277-3288
-
-
Yannaki, E.1
Papadopoulou, A.2
Athanasiou, E.3
-
57
-
-
70449727070
-
Bortezomib attenuates murine collagen-induced arthritis
-
Lee S.W., Kim J.H., Park Y.B., Lee S.K. Bortezomib attenuates murine collagen-induced arthritis. Ann Rheum Dis 2009, 68:1761-1767.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1761-1767
-
-
Lee, S.W.1
Kim, J.H.2
Park, Y.B.3
Lee, S.K.4
-
58
-
-
63049137443
-
The proteasome inhibitor bortezomib inhibits the release of NFkappaB-inducible cytokines and induces apoptosis of activated T cells from rheumatoid arthritis patients
-
van der Heijden J.W., Oerlemans R., Lems W.F., et al. The proteasome inhibitor bortezomib inhibits the release of NFkappaB-inducible cytokines and induces apoptosis of activated T cells from rheumatoid arthritis patients. Clin Exp Rheumatol 2009, 27:92-98.
-
(2009)
Clin Exp Rheumatol
, vol.27
, pp. 92-98
-
-
van der Heijden, J.W.1
Oerlemans, R.2
Lems, W.F.3
-
59
-
-
55249102985
-
Dual inhibition of proteasomal and lysosomal proteolysis ameliorates autoimmune central nervous system inflammation
-
Fissolo N., Kraus M., Reich M., et al. Dual inhibition of proteasomal and lysosomal proteolysis ameliorates autoimmune central nervous system inflammation. Eur J Immunol 2008, 38:2401-2411.
-
(2008)
Eur J Immunol
, vol.38
, pp. 2401-2411
-
-
Fissolo, N.1
Kraus, M.2
Reich, M.3
-
60
-
-
77954008149
-
Targeting the proteasome: Partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis
-
Schmidt N., Gonzalez E., Visekruna A., et al. Targeting the proteasome: Partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis. Gut 2010, 59:896-906.
-
(2010)
Gut
, vol.59
, pp. 896-906
-
-
Schmidt, N.1
Gonzalez, E.2
Visekruna, A.3
-
61
-
-
33745932074
-
Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation
-
Nencioni A., Schwarzenberg K., Brauer K.M., et al. Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation. Blood 2006, 108:551-558.
-
(2006)
Blood
, vol.108
, pp. 551-558
-
-
Nencioni, A.1
Schwarzenberg, K.2
Brauer, K.M.3
-
62
-
-
78751522626
-
Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis
-
Hirai M., Kadowaki N., Kitawaki T., et al. Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis. Blood 2011, 117:500-509.
-
(2011)
Blood
, vol.117
, pp. 500-509
-
-
Hirai, M.1
Kadowaki, N.2
Kitawaki, T.3
-
63
-
-
31544433927
-
Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells
-
Roccaro A.M., Hideshima T., Raje N., et al. Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells. Cancer Res 2006, 66:184-191.
-
(2006)
Cancer Res
, vol.66
, pp. 184-191
-
-
Roccaro, A.M.1
Hideshima, T.2
Raje, N.3
-
64
-
-
72449165023
-
Bortezomib and zoledronic acid on angiogenic and vasculogenic activities of bone marrow macrophages in patients with multiple myeloma
-
Moschetta M., Di Pietro G., Ria R., et al. Bortezomib and zoledronic acid on angiogenic and vasculogenic activities of bone marrow macrophages in patients with multiple myeloma. Eur J Cancer 2010, 46:420-429.
-
(2010)
Eur J Cancer
, vol.46
, pp. 420-429
-
-
Moschetta, M.1
Di Pietro, G.2
Ria, R.3
|