-
1
-
-
80755187806
-
Double-strand break end resection and repair pathway choice
-
Symington L.S., Gautier J. Double-strand break end resection and repair pathway choice. Annu. Rev. Genet. 2011, 45:247-271.
-
(2011)
Annu. Rev. Genet.
, vol.45
, pp. 247-271
-
-
Symington, L.S.1
Gautier, J.2
-
2
-
-
84866935347
-
The heterochromatic barrier to DNA double strand break repair: how to get the entry visa
-
Goodarzi A.A., Jeggo P.A. The heterochromatic barrier to DNA double strand break repair: how to get the entry visa. Int. J. Mol. Sci. 2012, 13:11844-11860.
-
(2012)
Int. J. Mol. Sci.
, vol.13
, pp. 11844-11860
-
-
Goodarzi, A.A.1
Jeggo, P.A.2
-
3
-
-
0037062492
-
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX
-
Bassing C.H., Chua K.F., Sekiguchi J., Suh H., Whitlow S.R., Fleming J.C., Monroe B.C., Ciccone D.N., Yan C., Vlasakova K., Livingston D.M., Ferguson D.O., Scully R., Alt F.W. Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:8173-8178.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 8173-8178
-
-
Bassing, C.H.1
Chua, K.F.2
Sekiguchi, J.3
Suh, H.4
Whitlow, S.R.5
Fleming, J.C.6
Monroe, B.C.7
Ciccone, D.N.8
Yan, C.9
Vlasakova, K.10
Livingston, D.M.11
Ferguson, D.O.12
Scully, R.13
Alt, F.W.14
-
4
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A., Petersen S., Romanienko P.J., Fernandez-Capetillo O., Chen H.T., Sedelnikova O.A., Reina-San-Martin B., Coppola V., Meffre E., Difilippantonio M.J., Redon C., Pilch D.R., Olaru A., Eckhaus M., Camerini-Otero R.D., Tessarollo L., Livak F., Manova K., Bonner W.M., Nussenzweig M.C., Nussenzweig A. Genomic instability in mice lacking histone H2AX. Science 2002, 296:922-927.
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
Sedelnikova, O.A.6
Reina-San-Martin, B.7
Coppola, V.8
Meffre, E.9
Difilippantonio, M.J.10
Redon, C.11
Pilch, D.R.12
Olaru, A.13
Eckhaus, M.14
Camerini-Otero, R.D.15
Tessarollo, L.16
Livak, F.17
Manova, K.18
Bonner, W.M.19
Nussenzweig, M.C.20
Nussenzweig, A.21
more..
-
5
-
-
65149084552
-
Crosstalk between histone modifications during the DNA damage response
-
van Attikum H., Gasser S.M. Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol. 2009, 19:207-217.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 207-217
-
-
van Attikum, H.1
Gasser, S.M.2
-
6
-
-
79251531097
-
Protein acetylation within the cellular response to radiation
-
Averbeck N.B., Durante M. Protein acetylation within the cellular response to radiation. J. Cell. Physiol. 2011, 226:962-967.
-
(2011)
J. Cell. Physiol.
, vol.226
, pp. 962-967
-
-
Averbeck, N.B.1
Durante, M.2
-
7
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
-
Polo S.E., Jackson S.P. Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev. 2011, 25:409-433.
-
(2011)
Genes Dev.
, vol.25
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
8
-
-
33644905252
-
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
-
Kruhlak M.J., Celeste A., Dellaire G., Fernandez-Capetillo O., Muller W.G., McNally J.G., Bazett-Jones D.P., Nussenzweig A. Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks. J. Cell Biol. 2006, 172:823-834.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 823-834
-
-
Kruhlak, M.J.1
Celeste, A.2
Dellaire, G.3
Fernandez-Capetillo, O.4
Muller, W.G.5
McNally, J.G.6
Bazett-Jones, D.P.7
Nussenzweig, A.8
-
9
-
-
33746601439
-
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway
-
Ziv Y., Bielopolski D., Galanty Y., Lukas C., Taya Y., Schultz D.C., Lukas J., Bekker-Jensen S., Bartek J., Shiloh Y. Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway. Nat. Cell Biol. 2006, 8:870-876.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 870-876
-
-
Ziv, Y.1
Bielopolski, D.2
Galanty, Y.3
Lukas, C.4
Taya, Y.5
Schultz, D.C.6
Lukas, J.7
Bekker-Jensen, S.8
Bartek, J.9
Shiloh, Y.10
-
10
-
-
34848852196
-
Chromatin dynamics during DSB repair
-
Falk M., Lukasova E., Gabrielova B., Ondrej V., Kozubek S. Chromatin dynamics during DSB repair. Biochim. Biophys. Acta 2007, 1773:1534-1545.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 1534-1545
-
-
Falk, M.1
Lukasova, E.2
Gabrielova, B.3
Ondrej, V.4
Kozubek, S.5
-
11
-
-
62849083222
-
The emerging role of nuclear architecture in DNA repair and genome maintenance
-
Misteli T., Soutoglou E. The emerging role of nuclear architecture in DNA repair and genome maintenance. Nat. Rev. Mol. Cell Biol. 2009, 10:243-254.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 243-254
-
-
Misteli, T.1
Soutoglou, E.2
-
12
-
-
55149112815
-
Chromatin structure influences the sensitivity of DNA to gamma-radiation
-
Falk M., Lukasova E., Kozubek S. Chromatin structure influences the sensitivity of DNA to gamma-radiation. Biochim. Biophys. Acta 2008, 1783:2398-2414.
-
(2008)
Biochim. Biophys. Acta
, vol.1783
, pp. 2398-2414
-
-
Falk, M.1
Lukasova, E.2
Kozubek, S.3
-
13
-
-
47349107760
-
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
-
Goodarzi A.A., Noon A.T., Deckbar D., Ziv Y., Shiloh Y., Lobrich M., Jeggo P.A. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell 2008, 31:167-177.
-
(2008)
Mol. Cell
, vol.31
, pp. 167-177
-
-
Goodarzi, A.A.1
Noon, A.T.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
Lobrich, M.6
Jeggo, P.A.7
-
14
-
-
79961207835
-
DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin
-
Jakob B., Splinter J., Conrad S., Voss K.O., Zink D., Durante M., Lobrich M., Taucher-Scholz G. DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin. Nucleic Acids Res. 2011, 39:6489-6499.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 6489-6499
-
-
Jakob, B.1
Splinter, J.2
Conrad, S.3
Voss, K.O.4
Zink, D.5
Durante, M.6
Lobrich, M.7
Taucher-Scholz, G.8
-
15
-
-
79952314830
-
Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair
-
Chiolo I., Minoda A., Colmenares S.U., Polyzos A., Costes S.V., Karpen G.H. Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair. Cell 2011, 144:732-744.
-
(2011)
Cell
, vol.144
, pp. 732-744
-
-
Chiolo, I.1
Minoda, A.2
Colmenares, S.U.3
Polyzos, A.4
Costes, S.V.5
Karpen, G.H.6
-
16
-
-
34547591933
-
The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus
-
Torres-Rosell J., Sunjevaric I., De Piccoli G., Sacher M., Eckert-Boulet N., Reid R., Jentsch S., Rothstein R., Aragon L., Lisby M. The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus. Nat. Cell Biol. 2007, 9:923-931.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 923-931
-
-
Torres-Rosell, J.1
Sunjevaric, I.2
De Piccoli, G.3
Sacher, M.4
Eckert-Boulet, N.5
Reid, R.6
Jentsch, S.7
Rothstein, R.8
Aragon, L.9
Lisby, M.10
-
17
-
-
44349186294
-
Epigenetic regulation of heterochromatic DNA stability
-
Peng J.C., Karpen G.H. Epigenetic regulation of heterochromatic DNA stability. Curr. Opin. Genet. Dev. 2008, 18:204-211.
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, pp. 204-211
-
-
Peng, J.C.1
Karpen, G.H.2
-
18
-
-
31444435046
-
Targeted irradiation of mammalian cells using a heavy-ion microprobe
-
Heiss M., Fischer B.E., Jakob B., Fournier C., Becker G., Taucher-Scholz G. Targeted irradiation of mammalian cells using a heavy-ion microprobe. Radiat. Res. 2006, 165:231-239.
-
(2006)
Radiat. Res.
, vol.165
, pp. 231-239
-
-
Heiss, M.1
Fischer, B.E.2
Jakob, B.3
Fournier, C.4
Becker, G.5
Taucher-Scholz, G.6
-
19
-
-
0038301384
-
Biological imaging of heavy charged-particle tracks
-
Jakob B., Scholz M., Taucher-Scholz G. Biological imaging of heavy charged-particle tracks. Radiat. Res. 2003, 159:676-684.
-
(2003)
Radiat. Res.
, vol.159
, pp. 676-684
-
-
Jakob, B.1
Scholz, M.2
Taucher-Scholz, G.3
-
20
-
-
62549097982
-
Positional stability of damaged chromatin domains along radiation tracks in mammalian cells
-
Jakob B., Splinter J., Taucher-Scholz G. Positional stability of damaged chromatin domains along radiation tracks in mammalian cells. Radiat. Res. 2009, 171:405-418.
-
(2009)
Radiat. Res.
, vol.171
, pp. 405-418
-
-
Jakob, B.1
Splinter, J.2
Taucher-Scholz, G.3
-
21
-
-
84879053998
-
-
Photobleaching setup for the biological end-station of the Darmstadt heavy-ion microprobe, NIMB Proceedings, doi:10.1016/j.nimb.2012.11.043
-
B. Merk, K.O. Voss, I. Müller, B.E. Fischer, B. Jakob, G. Taucher-Scholz, C. Trautmann, M. Durante, Photobleaching setup for the biological end-station of the Darmstadt heavy-ion microprobe, NIMB Proceedings, doi:10.1016/j.nimb.2012.11.043.
-
-
-
Merk, B.1
Voss, K.O.2
Müller, I.3
Fischer, B.E.4
Jakob, B.5
Taucher-Scholz, G.6
Trautmann, C.7
Durante, M.8
-
22
-
-
0030454586
-
Three-dimensional reconstruction of painted human interphase chromosomes: active and inactive X chromosome territories have similar volumes but differ in shape and surface structure
-
Eils R., Dietzel S., Bertin E., Schrock E., Speicher M.R., Ried T., Robert-Nicoud M., Cremer C., Cremer T. Three-dimensional reconstruction of painted human interphase chromosomes: active and inactive X chromosome territories have similar volumes but differ in shape and surface structure. J. Cell Biol. 1996, 135:1427-1440.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1427-1440
-
-
Eils, R.1
Dietzel, S.2
Bertin, E.3
Schrock, E.4
Speicher, M.R.5
Ried, T.6
Robert-Nicoud, M.7
Cremer, C.8
Cremer, T.9
-
23
-
-
0242668706
-
Role of histone H3 lysine 27 methylation in X inactivation
-
Plath K., Fang J., Mlynarczyk-Evans S.K., Cao R., Worringer K.A., Wang H., de la Cruz C.C., Otte A.P., Panning B., Zhang Y. Role of histone H3 lysine 27 methylation in X inactivation. Science 2003, 300:131-135.
-
(2003)
Science
, vol.300
, pp. 131-135
-
-
Plath, K.1
Fang, J.2
Mlynarczyk-Evans, S.K.3
Cao, R.4
Worringer, K.A.5
Wang, H.6
de la Cruz, C.C.7
Otte, A.P.8
Panning, B.9
Zhang, Y.10
-
24
-
-
10644221120
-
Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome
-
Chadwick B.P., Willard H.F. Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:17450-17455.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 17450-17455
-
-
Chadwick, B.P.1
Willard, H.F.2
-
25
-
-
74949108644
-
The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks
-
Nakamura A.J., Rao V.A., Pommier Y., Bonner W.M. The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks. Cell Cycle 2010, 9:389-397.
-
(2010)
Cell Cycle
, vol.9
, pp. 389-397
-
-
Nakamura, A.J.1
Rao, V.A.2
Pommier, Y.3
Bonner, W.M.4
-
26
-
-
77951967843
-
Biological dose estimation of UVA laser microirradiation utilizing charged particle-induced protein foci
-
Splinter J., Jakob B., Lang M., Yano K., Engelhardt J., Hell S.W., Chen D.J., Durante M., Taucher-Scholz G. Biological dose estimation of UVA laser microirradiation utilizing charged particle-induced protein foci. Mutagenesis 2010, 25:289-297.
-
(2010)
Mutagenesis
, vol.25
, pp. 289-297
-
-
Splinter, J.1
Jakob, B.2
Lang, M.3
Yano, K.4
Engelhardt, J.5
Hell, S.W.6
Chen, D.J.7
Durante, M.8
Taucher-Scholz, G.9
-
27
-
-
27944496485
-
BRCA1 associates with the inactive X chromosome in late S-phase, coupled with transient H2AX phosphorylation
-
Chadwick B.P., Lane T.F. BRCA1 associates with the inactive X chromosome in late S-phase, coupled with transient H2AX phosphorylation. Chromosoma 2005, 114:432-439.
-
(2005)
Chromosoma
, vol.114
, pp. 432-439
-
-
Chadwick, B.P.1
Lane, T.F.2
-
28
-
-
84869105709
-
The WSTF-ISWI chromatin remodeling complex transiently associates with the human inactive X chromosome during late S-phase prior to BRCA1 and gamma-H2AX
-
Culver-Cochran A.E., Chadwick B.P. The WSTF-ISWI chromatin remodeling complex transiently associates with the human inactive X chromosome during late S-phase prior to BRCA1 and gamma-H2AX. PLoS ONE 2012, 7:e50023.
-
(2012)
PLoS ONE
, vol.7
-
-
Culver-Cochran, A.E.1
Chadwick, B.P.2
-
29
-
-
33845866637
-
H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability
-
Peng J.C., Karpen G.H. H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability. Nat. Cell Biol. 2007, 9:25-35.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 25-35
-
-
Peng, J.C.1
Karpen, G.H.2
-
30
-
-
63449109369
-
Heterochromatic genome stability requires regulators of histone H3 K9 methylation
-
Peng J.C., Karpen G.H. Heterochromatic genome stability requires regulators of histone H3 K9 methylation. PLoS Genet. 2009, 5:e1000435.
-
(2009)
PLoS Genet.
, vol.5
-
-
Peng, J.C.1
Karpen, G.H.2
-
31
-
-
33646743365
-
The X chromosome is organized into a gene-rich outer rim and an internal core containing silenced nongenic sequences
-
Clemson C.M., Hall L.L., Byron M., McNeil J., Lawrence J.B. The X chromosome is organized into a gene-rich outer rim and an internal core containing silenced nongenic sequences. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:7688-7693.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 7688-7693
-
-
Clemson, C.M.1
Hall, L.L.2
Byron, M.3
McNeil, J.4
Lawrence, J.B.5
-
32
-
-
80052146061
-
Chromatin and the DNA damage response: the cancer connection
-
Luijsterburg M.S., van Attikum H. Chromatin and the DNA damage response: the cancer connection. Mol. Oncol. 2011, 5:349-367.
-
(2011)
Mol. Oncol.
, vol.5
, pp. 349-367
-
-
Luijsterburg, M.S.1
van Attikum, H.2
-
33
-
-
80053589357
-
Analysis of human syndromes with disordered chromatin reveals the impact of heterochromatin on the efficacy of ATM-dependent G2/M checkpoint arrest
-
Brunton H., Goodarzi A.A., Noon A.T., Shrikhande A., Hansen R.S., Jeggo P.A., Shibata A. Analysis of human syndromes with disordered chromatin reveals the impact of heterochromatin on the efficacy of ATM-dependent G2/M checkpoint arrest. Mol. Cell. Biol. 2011, 31:4022-4035.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 4022-4035
-
-
Brunton, H.1
Goodarzi, A.A.2
Noon, A.T.3
Shrikhande, A.4
Hansen, R.S.5
Jeggo, P.A.6
Shibata, A.7
-
34
-
-
43149100549
-
The facultative heterochromatin of the inactive X chromosome has a distinctive condensed ultrastructure
-
Rego A., Sinclair P.B., Tao W., Kireev I., Belmont A.S. The facultative heterochromatin of the inactive X chromosome has a distinctive condensed ultrastructure. J. Cell Sci. 2008, 121:1119-1127.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 1119-1127
-
-
Rego, A.1
Sinclair, P.B.2
Tao, W.3
Kireev, I.4
Belmont, A.S.5
-
35
-
-
79955625071
-
Constitutive heterochromatin reorganization during somatic cell reprogramming
-
Fussner E., Djuric U., Strauss M., Hotta A., Perez-Iratxeta C., Lanner F., Dilworth F.J., Ellis J., Bazett-Jones D.P. Constitutive heterochromatin reorganization during somatic cell reprogramming. EMBO J. 2011, 30:1778-1789.
-
(2011)
EMBO J.
, vol.30
, pp. 1778-1789
-
-
Fussner, E.1
Djuric, U.2
Strauss, M.3
Hotta, A.4
Perez-Iratxeta, C.5
Lanner, F.6
Dilworth, F.J.7
Ellis, J.8
Bazett-Jones, D.P.9
-
36
-
-
80054705013
-
A top-down analysis of Xa- and Xi-territories reveals differences of higher order structure at ≥20Mb genomic length scales
-
Teller K., Illner D., Thamm S., Casas-Delucchi C.S., Versteeg R., Indemans M., Cremer T., Cremer M. A top-down analysis of Xa- and Xi-territories reveals differences of higher order structure at ≥20Mb genomic length scales. Nucleus 2011, 2:465-477.
-
(2011)
Nucleus
, vol.2
, pp. 465-477
-
-
Teller, K.1
Illner, D.2
Thamm, S.3
Casas-Delucchi, C.S.4
Versteeg, R.5
Indemans, M.6
Cremer, T.7
Cremer, M.8
-
38
-
-
78649349810
-
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
-
Chou D.M., Adamson B., Dephoure N.E., Tan X., Nottke A.C., Hurov K.E., Gygi S.P., Colaiacovo M.P., Elledge S.J. A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:18475-18480.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 18475-18480
-
-
Chou, D.M.1
Adamson, B.2
Dephoure, N.E.3
Tan, X.4
Nottke, A.C.5
Hurov, K.E.6
Gygi, S.P.7
Colaiacovo, M.P.8
Elledge, S.J.9
-
39
-
-
82955249089
-
Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4
-
Seiler D.M., Rouquette J., Schmid V.J., Strickfaden H., Ottmann C., Drexler G.A., Mazurek B., Greubel C., Hable V., Dollinger G., Cremer T., Friedl A.A. Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4. Chromosome Res. 2011, 19:883-899.
-
(2011)
Chromosome Res.
, vol.19
, pp. 883-899
-
-
Seiler, D.M.1
Rouquette, J.2
Schmid, V.J.3
Strickfaden, H.4
Ottmann, C.5
Drexler, G.A.6
Mazurek, B.7
Greubel, C.8
Hable, V.9
Dollinger, G.10
Cremer, T.11
Friedl, A.A.12
|