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Volumn 58, Issue 9, 2013, Pages 2705-2712

Insulin-like growth factor 1 receptor promotes the growth and chemoresistance of pancreatic cancer

Author keywords

Chemosensitivity; Gemcitabine; Insulin like growth factor 1 receptor; Pancreatic cancer

Indexed keywords

GEMCITABINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LENTIVIRUS VECTOR; PROTEIN KINASE B; SHORT HAIRPIN RNA; SOMATOMEDIN C RECEPTOR;

EID: 84884204473     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-013-2673-2     Document Type: Article
Times cited : (28)

References (18)
  • 1
    • 84856723290 scopus 로고    scopus 로고
    • Novel medical therapies of recurrent and metastatic gastroenteropancreatic neuroendocrine tumors
    • 21938486 10.1007/s10620-011-1854-0
    • Miljković MD, Girotra M, Abraham RR, Erlich RB. Novel medical therapies of recurrent and metastatic gastroenteropancreatic neuroendocrine tumors. Dig Dis Sci. 2012;57:9-18.
    • (2012) Dig Dis Sci , vol.57 , pp. 9-18
    • Miljković, M.D.1    Girotra, M.2    Abraham, R.R.3    Erlich, R.B.4
  • 2
    • 79951773787 scopus 로고    scopus 로고
    • Clinical significance of vascular endothelial growth factor and connexin43 for predicting pancreatic cancer clinicopathologic parameters
    • 19908168 10.1007/s12032-009-9354-1 1:CAS:528:DC%2BC3cXhsVGrt7jJ
    • Liang QL, Wang BR, Chen GQ, Li GH, Xu YY. Clinical significance of vascular endothelial growth factor and connexin43 for predicting pancreatic cancer clinicopathologic parameters. Med Oncol. 2010;27:1164-1170.
    • (2010) Med Oncol , vol.27 , pp. 1164-1170
    • Liang, Q.L.1    Wang, B.R.2    Chen, G.Q.3    Li, G.H.4    Xu, Y.Y.5
  • 3
    • 28544444712 scopus 로고    scopus 로고
    • Type i insulin-like growth factor receptor as a therapeutic target in cancer
    • 16287993 10.1158/0008-5472.CAN-05-2752 1:CAS:528:DC%2BD2MXht1WgurjF
    • Miller BS, Yee D. Type I insulin-like growth factor receptor as a therapeutic target in cancer. Cancer Res. 2005;65:10123-10127.
    • (2005) Cancer Res , vol.65 , pp. 10123-10127
    • Miller, B.S.1    Yee, D.2
  • 4
    • 33846807433 scopus 로고    scopus 로고
    • Disrupting insulin-like growth factor signaling as a potential cancer therapy
    • 17237261 10.1158/1535-7163.MCT-06-0080 1:CAS:528:DC%2BD2sXmsVantg%3D%3D
    • Sachdev D, Yee D. Disrupting insulin-like growth factor signaling as a potential cancer therapy. Mol Cancer Ther. 2007;6:1-12.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1-12
    • Sachdev, D.1    Yee, D.2
  • 5
    • 84871639614 scopus 로고    scopus 로고
    • MiR-17-5p inhibitor enhances chemosensitivity to gemcitabine via upregulating Bim expression in pancreatic cancer cells
    • 23001407 10.1007/s10620-012-2400-4 1:CAS:528:DC%2BC38Xhslaqt7nK
    • Yan HJ, Liu WS, Sun WH, et al. miR-17-5p inhibitor enhances chemosensitivity to gemcitabine via upregulating Bim expression in pancreatic cancer cells. Dig Dis Sci. 2012;57:3160-3167.
    • (2012) Dig Dis Sci , vol.57 , pp. 3160-3167
    • Yan, H.J.1    Liu, W.S.2    Sun, W.H.3
  • 6
    • 0028997487 scopus 로고
    • Insulin-like growth factor i overexpression in human pancreatic cancer: Evidence for autocrine and paracrine roles
    • 7743492 1:CAS:528:DyaK2MXls1OlurY%3D
    • Bergmann U, Funatomi H, Yokoyama M, Beger HG, Korc M. Insulin-like growth factor I overexpression in human pancreatic cancer: evidence for autocrine and paracrine roles. Cancer Res. 1995;55:2007-2011.
    • (1995) Cancer Res , vol.55 , pp. 2007-2011
    • Bergmann, U.1    Funatomi, H.2    Yokoyama, M.3    Beger, H.G.4    Korc, M.5
  • 7
    • 77953641778 scopus 로고    scopus 로고
    • Biological rationale and current clinical experience with anti-insulin-like growth factor 1 receptor monoclonal antibodies in treating sarcoma: Twenty years from the bench to the bedside
    • 20526094 10.1097/PPO.0b013e3181dbebf9 1:CAS:528:DC%2BC3cXovV2rt74%3D
    • Olmos D, Tan DS, Jones RL, Judson IR. Biological rationale and current clinical experience with anti-insulin-like growth factor 1 receptor monoclonal antibodies in treating sarcoma: twenty years from the bench to the bedside. Cancer J. 2010;16:183-194.
    • (2010) Cancer J , vol.16 , pp. 183-194
    • Olmos, D.1    Tan, D.S.2    Jones, R.L.3    Judson, I.R.4
  • 8
    • 66849140937 scopus 로고    scopus 로고
    • AMG 479, a fully human anti-insulin-like growth factor receptor type i monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells
    • 19366899 10.1158/1535-7163.MCT-08-1171 1:CAS:528:DC%2BD1MXmtlGqsLY%3D
    • Beltran PJ, Mitchell P, Chung YA, et al. AMG 479, a fully human anti-insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells. Mol Cancer Ther. 2009;8:1095-1105.
    • (2009) Mol Cancer Ther , vol.8 , pp. 1095-1105
    • Beltran, P.J.1    Mitchell, P.2    Chung, Y.A.3
  • 9
    • 79961010790 scopus 로고    scopus 로고
    • The efficacy of IGF-I receptor monoclonal antibody against human gastrointestinal carcinomas is independent of k-ras mutation status
    • 21642381 10.1158/1078-0432.CCR-10-3131
    • Li M, Li H, Adachi Y, et al. The efficacy of IGF-I receptor monoclonal antibody against human gastrointestinal carcinomas is independent of k-ras mutation status. Clin Cancer Res. 2011;17:5048-5059.
    • (2011) Clin Cancer Res , vol.17 , pp. 5048-5059
    • Li, M.1    Li, H.2    Adachi, Y.3
  • 10
    • 59449101038 scopus 로고    scopus 로고
    • Detection and downregulation of type i IGF receptor expression by antibody-conjugated quantum dots in breast cancer cells
    • 18418709 10.1007/s10549-008-0014-5 1:CAS:528:DC%2BD1MXhsFWnu70%3D
    • Zhang H, Sachdev D, Wang C, Hubel A, Gaillard-Kelly M, Yee D. Detection and downregulation of type I IGF receptor expression by antibody-conjugated quantum dots in breast cancer cells. Breast Cancer Res Treat. 2009;114:277-285.
    • (2009) Breast Cancer Res Treat , vol.114 , pp. 277-285
    • Zhang, H.1    Sachdev, D.2    Wang, C.3    Hubel, A.4    Gaillard-Kelly, M.5    Yee, D.6
  • 11
    • 79959284354 scopus 로고    scopus 로고
    • Down-regulation of IGF-1R expression inhibits growth and enhances chemosensitivity of endometrial carcinoma in vitro
    • 21442237 10.1007/s11010-011-0790-9 1:CAS:528:DC%2BC3MXmslyjtL8%3D
    • Shu S, Yang Y, Li X, et al. Down-regulation of IGF-1R expression inhibits growth and enhances chemosensitivity of endometrial carcinoma in vitro. Mol Cell Biochem. 2011;353:225-233.
    • (2011) Mol Cell Biochem , vol.353 , pp. 225-233
    • Shu, S.1    Yang, Y.2    Li, X.3
  • 12
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • 9196156 1:CAS:528:DyaK2sXlsFKksLY%3D
    • Burris HA III, Moore MJ, Andersen J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol. 1997;15:2403-2413.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris III, H.A.1    Moore, M.J.2    Andersen, J.3
  • 13
    • 1242319394 scopus 로고    scopus 로고
    • Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis
    • 14750167 10.1002/ijc.11679 1:CAS:528:DC%2BD2cXhvVClu7k%3D
    • Schniewind B, Christgen M, Kurdow R, et al. Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis. Int J Cancer. 2004;109:182-188.
    • (2004) Int J Cancer , vol.109 , pp. 182-188
    • Schniewind, B.1    Christgen, M.2    Kurdow, R.3
  • 14
    • 0034792844 scopus 로고    scopus 로고
    • Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice
    • 11595724 1:CAS:528:DC%2BD3MXnvF2rs7k%3D
    • Ng SS, Tsao MS, Nicklee T, Hedley DW. Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice. Clin Cancer Res. 2001;7:3269-3275.
    • (2001) Clin Cancer Res , vol.7 , pp. 3269-3275
    • Ng, S.S.1    Tsao, M.S.2    Nicklee, T.3    Hedley, D.W.4
  • 15
    • 0036327139 scopus 로고    scopus 로고
    • NFkappaB-dependent chemoresistance in solid tumors
    • 12467302 10.5414/CPP40336 1:CAS:528:DC%2BD38XmsVamsLs%3D
    • Arlt A, Schäfer H. NFkappaB-dependent chemoresistance in solid tumors. Int J Clin Pharmacol Ther. 2002;40:336-347.
    • (2002) Int J Clin Pharmacol Ther , vol.40 , pp. 336-347
    • Arlt, A.1    Schäfer, H.2
  • 17
    • 0034142254 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation
    • 10640750 1:CAS:528:DC%2BD3cXot1Grtw%3D%3D
    • Reddy SA, Huang JH, Liao WS. Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation. J Immunol. 2000;164:1355-1363.
    • (2000) J Immunol , vol.164 , pp. 1355-1363
    • Reddy, S.A.1    Huang, J.H.2    Liao, W.S.3
  • 18
    • 84863022415 scopus 로고    scopus 로고
    • Inhibition of AKT2 enhances sensitivity to gemcitabine via regulating PUMA and NF-κB signaling pathway in human pancreatic ductal adenocarcinoma
    • 22312312 10.3390/ijms13011186 1:CAS:528:DC%2BC38XitFemsbs%3D
    • Chen D, Niu M, Jiao X, Zhang K, Liang J, Zhang D. Inhibition of AKT2 enhances sensitivity to gemcitabine via regulating PUMA and NF-κB signaling pathway in human pancreatic ductal adenocarcinoma. Int J Mol Sci. 2012;13:1186-1208.
    • (2012) Int J Mol Sci , vol.13 , pp. 1186-1208
    • Chen, D.1    Niu, M.2    Jiao, X.3    Zhang, K.4    Liang, J.5    Zhang, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.