메뉴 건너뛰기




Volumn 121, Issue 26, 2013, Pages 5124-5130

Systemic light chain amyloidosis: An update for treating physicians

Author keywords

[No Author keywords available]

Indexed keywords

BENDAMUSTINE; BORTEZOMIB; CARFILZOMIB; CONGO RED; CYCLOPHOSPHAMIDE; DEXAMETHASONE; IMMUNOGLOBULIN LIGHT CHAIN; IXAZOMIB; LENALIDOMIDE; MELPHALAN; POMALIDOMIDE; THALIDOMIDE;

EID: 84884171906     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-01-453001     Document Type: Article
Times cited : (204)

References (80)
  • 1
    • 0042709605 scopus 로고    scopus 로고
    • Molecular mechanisms of amyloidosis
    • DOI 10.1056/NEJMra023144
    • Merlini G, Bellotti V. Molecular mechanisms of amyloidosis. N Engl J Med. 2003;349(6): 583-596. (Pubitemid 36951371)
    • (2003) New England Journal of Medicine , vol.349 , Issue.6 , pp. 583-596
    • Merlini, G.1    Bellotti, V.2
  • 2
    • 0026519157 scopus 로고
    • Incidence and natural history of primary systemic amyloidosis in olmsted county minnesota 1950 through 1989
    • Kyle RA, Linos A, Beard CM, et al. Incidence and natural history of primary systemic amyloidosis in Olmsted County, Minnesota, 1950 through 1989. Blood. 1992;79(7):1817-1822.
    • (1992) Blood , vol.79 , Issue.7 , pp. 1817-1822
    • Kyle, R.A.1    Linos, A.2    Beard, C.M.3
  • 3
    • 79955842001 scopus 로고    scopus 로고
    • Amyloidosis: Pathogenesis and new therapeutic options
    • Merlini G, Seldin DC, Gertz MA. Amyloidosis: pathogenesis and new therapeutic options. J Clin Oncol. 2011;29(14):1924-1933.
    • (2011) J Clin Oncol , vol.29 , Issue.14 , pp. 1924-1933
    • Merlini, G.1    Seldin, D.C.2    Gertz, M.A.3
  • 4
    • 33750616035 scopus 로고    scopus 로고
    • Dangerous small B-cell clones
    • Merlini G, Stone MJ. Dangerous small B-cell clones. Blood. 2006;108(8):2520-2530.
    • (2006) Blood , vol.108 , Issue.8 , pp. 2520-2530
    • Merlini, G.1    Stone, M.J.2
  • 5
    • 0032827077 scopus 로고    scopus 로고
    • Clonal immunoglobulin light chain variable region germline gene use in AL amyloidosis: Association with dominant amyloid-related organ involvement and survival after stem cell transplantation
    • DOI 10.1046/j.1365-2141.1999.01591.x
    • Comenzo RL, Wally J, Kica G, et al. Clonal immunoglobulin light chain variable region germline gene use in AL amyloidosis: association with dominant amyloid-related organ involvement.Br J Haematol 1999 106 3 744-751 (Pubitemid 29434217)
    • (1999) British Journal of Haematology , vol.106 , Issue.3 , pp. 744-751
    • Comenzo, R.L.1    Wally, J.2    Kica, G.3    Murray, J.4    Ericsson, T.5    Skinner, M.6    Zhang, Y.7
  • 6
    • 84855614136 scopus 로고    scopus 로고
    • The repertoire of l light chains causing predominant amyloid heart involvement and identification of a preferentially involved germline gene IGLV1-44
    • Perfetti V, Palladini G, Casarini S, et al. The repertoire of l light chains causing predominant amyloid heart involvement and identification of a preferentially involved germline gene, IGLV1-44. Blood. 2012;119(1):144-150.
    • (2012) Blood , vol.119 , Issue.1 , pp. 144-150
    • Perfetti, V.1    Palladini, G.2    Casarini, S.3
  • 7
    • 78650987230 scopus 로고    scopus 로고
    • Recent improvements in survival in primary systemic amyloidosis and the importance of an early mortality risk score
    • Kumar SK, Gertz MA, Lacy MQ, et al. Recent improvements in survival in primary systemic amyloidosis and the importance of an early mortality risk score. Mayo Clin Proc. 2011;86(1): 12-18.
    • (2011) Mayo Clin Proc , vol.86 , Issue.1 , pp. 12-18
    • Kumar, S.K.1    Gertz, M.A.2    Lacy, M.Q.3
  • 8
    • 84860895856 scopus 로고    scopus 로고
    • CyBorD: Stellar response rates in AL amyloidosis
    • Merlini G. CyBorD: stellar response rates in AL amyloidosis. Blood. 2012;119(19):4343-4345.
    • (2012) Blood , vol.119 , Issue.19 , pp. 4343-4345
    • Merlini, G.1
  • 10
    • 79960015354 scopus 로고    scopus 로고
    • Abnormal N-terminal fragment of brain natriuretic peptide in patients with light chain amyloidosis without cardiac involvement at presentation is a risk factor for development of cardiac amyloidosis
    • Wechalekar AD, Gillmore JD, Wassef N, Lachmann HJ, Whelan C, Hawkins PN. Abnormal N-terminal fragment of brain natriuretic peptide in patients with light chain amyloidosis without cardiac involvement at presentation is a risk factor for development of cardiac amyloidosis. Haematologica. 2011;96(7):1079-1080.
    • (2011) Haematologica , vol.96 , Issue.7 , pp. 1079-1080
    • Wechalekar, A.D.1    Gillmore, J.D.2    Wassef, N.3    Lachmann, H.J.4    Whelan, C.5    Hawkins, P.N.6
  • 11
    • 77954610729 scopus 로고    scopus 로고
    • Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management
    • Kyle RA, Durie BG, Rajkumar SV, et al; International Myeloma Working Group. Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management. Leukemia. 2010;24(6):1121-1127.
    • (2010) Leukemia , vol.24 , Issue.6 , pp. 1121-1127
    • Kyle, R.A.1    Durie, B.G.2    Rajkumar, S.V.3
  • 13
    • 84868374880 scopus 로고    scopus 로고
    • Nomenclature committee of the international society of amyloidosis. Amyloid fibril protein nomenclature: 2012 recommendations from the nomenclature committee of the international society of amyloidosis
    • Sipe JD, Benson MD, Buxbaum JN, et al; Nomenclature Committee of the International Society of Amyloidosis. Amyloid fibril protein nomenclature: 2012 recommendations from the Nomenclature Committee of the International Society of Amyloidosis. Amyloid. 2012;19(4): 167-170.
    • (2012) Amyloid , vol.19 , Issue.4 , pp. 167-170
    • Sipe, J.D.1    Benson, M.D.2    Buxbaum, J.N.3
  • 14
    • 76149083590 scopus 로고    scopus 로고
    • Structural typing of systemic amyloidoses by luminescentconjugated polymer spectroscopy
    • Nilsson KP, Ikenberg K, Aslund A, et al. Structural typing of systemic amyloidoses by luminescentconjugated polymer spectroscopy. Am J Pathol. 2010;176(2):563-574.
    • (2010) Am J Pathol , vol.176 , Issue.2 , pp. 563-574
    • Nilsson, K.P.1    Ikenberg, K.2    Aslund, A.3
  • 15
    • 79960014743 scopus 로고    scopus 로고
    • The role of minor salivary gland biopsy in the diagnosis of systemic amyloidosis: Results of a prospective study in 62 patients
    • Foli A, Palladini G, Caporali R, et al. The role of minor salivary gland biopsy in the diagnosis of systemic amyloidosis: results of a prospective study in 62 patients. Amyloid. 2011;18(suppl 1): 80-82.
    • (2011) Amyloid , vol.18 , Issue.SUPPL. 1 , pp. 80-82
    • Foli, A.1    Palladini, G.2    Caporali, R.3
  • 16
    • 73949091104 scopus 로고    scopus 로고
    • Classification of amyloidosis by laser microdissection and mass spectrometry-based proteomic analysis in clinical biopsy specimens
    • Vrana JA, Gamez JD, Madden BJ, Theis JD, Bergen HR III, Dogan A. Classification of amyloidosis by laser microdissection and mass spectrometry-based proteomic analysis in clinical biopsy specimens. Blood. 2009;114(24): 4957-4959.
    • (2009) Blood , vol.114 , Issue.24 , pp. 4957-4959
    • Vrana, J.A.1    Gamez, J.D.2    Madden, B.J.3    Theis, J.D.4    Bergen III, H.R.5    Dogan, A.6
  • 17
    • 84855822559 scopus 로고    scopus 로고
    • Reliable typing of systemic amyloidoses through proteomic analysis of subcutaneous adipose tissue
    • Brambilla F, Lavatelli F, Di Silvestre D, et al. Reliable typing of systemic amyloidoses through proteomic analysis of subcutaneous adipose tissue. Blood. 2012;119(8):1844-1847.
    • (2012) Blood , vol.119 , Issue.8 , pp. 1844-1847
    • Brambilla, F.1    Lavatelli, F.2    Di Silvestre, D.3
  • 19
    • 84855838187 scopus 로고    scopus 로고
    • Immunohistochemistry in the classification of systemic forms of amyloidosis: A systematic investigation of 117 patients
    • Schönland SO, Hegenbart U, Bochtler T, et al. Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients. Blood. 2012;119(2): 488-493.
    • (2012) Blood , vol.119 , Issue.2 , pp. 488-493
    • Schönland, S.O.1    Hegenbart, U.2    Bochtler, T.3
  • 21
    • 33646241631 scopus 로고    scopus 로고
    • Seeking confidence in the diagnosis of systemic AL (Ig light-chain) amyloidosis: Patients can have both monoclonal gammopathies and hereditary amyloid proteins
    • Comenzo RL, Zhou P, Fleisher M, Clark B, Teruya-Feldstein J. Seeking confidence in the diagnosis of systemic AL (Ig light-chain) amyloidosis: patients can have both monoclonal gammopathies and hereditary amyloid proteins. Blood. 2006;107(9):3489-3491.
    • (2006) Blood , vol.107 , Issue.9 , pp. 3489-3491
    • Comenzo, R.L.1    Zhou, P.2    Fleisher, M.3    Clark, B.4    Teruya-Feldstein, J.5
  • 22
    • 62149124802 scopus 로고    scopus 로고
    • Identification of amyloidogenic light chains requires the combination of serum-free light chain assay with immunofixation of serum and urine
    • Palladini G, Russo P, Bosoni T, et al. Identification of amyloidogenic light chains requires the combination of serum-free light chain assay with immunofixation of serum and urine. Clin Chem. 2009;55(3):499-504.
    • (2009) Clin Chem , vol.55 , Issue.3 , pp. 499-504
    • Palladini, G.1    Russo, P.2    Bosoni, T.3
  • 23
    • 25444434458 scopus 로고    scopus 로고
    • Diagnosis and management of the cardiac amyloidoses
    • DOI 10.1161/CIRCULATIONAHA.104.489187
    • Falk RH. Diagnosis and management of the cardiac amyloidoses. Circulation. 2005;112(13): 2047-2060. (Pubitemid 41377426)
    • (2005) Circulation , vol.112 , Issue.13 , pp. 2047-2060
    • Falk, R.H.1
  • 24
    • 84866078444 scopus 로고    scopus 로고
    • Longitudinal left ventricular function for prediction of survival in systemic light-chain amyloidosis: Incremental value compared with clinical and biochemical markers
    • Buss SJ, Emami M, Mereles D, et al. Longitudinal left ventricular function for prediction of survival in systemic light-chain amyloidosis: incremental value compared with clinical and biochemical markers. J Am Coll Cardiol. 2012;60(12): 1067-1076.
    • (2012) J Am Coll Cardiol , vol.60 , Issue.12 , pp. 1067-1076
    • Buss, S.J.1    Emami, M.2    Mereles, D.3
  • 25
    • 84874533688 scopus 로고    scopus 로고
    • Quantification of myocardial extracellular volume fraction in systemic AL amyloidosis: An equilibrium contrast cardiovascular magnetic resonance study
    • Banypersad SM, Sado DM, Flett AS, et al. Quantification of myocardial extracellular volume fraction in systemic AL amyloidosis: an equilibrium contrast cardiovascular magnetic resonance study. Circ Cardiovasc Imaging. 2013; 6(1):34-39.
    • (2013) Circ Cardiovasc Imaging , vol.6 , Issue.1 , pp. 34-39
    • Banypersad, S.M.1    Sado, D.M.2    Flett, A.S.3
  • 26
  • 27
    • 79953733503 scopus 로고    scopus 로고
    • Usefulness and limitations of 99mTc-3,3- diphosphono-1,2- propanodicarboxylic acid scintigraphy in the aetiological diagnosis of amyloidotic cardiomyopathy
    • Rapezzi C, Quarta CC, Guidalotti PL, et al. Usefulness and limitations of 99mTc-3,3- diphosphono-1,2-propanodicarboxylic acid scintigraphy in the aetiological diagnosis of amyloidotic cardiomyopathy. Eur J Nucl Med Mol Imaging. 2011;38(3):470-478.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , Issue.3 , pp. 470-478
    • Rapezzi, C.1    Quarta, C.C.2    Guidalotti, P.L.3
  • 28
    • 84879458198 scopus 로고    scopus 로고
    • A European collaborative study of treatment outcomes in 346 patients with cardiac stage III AL amyloidosis
    • Wechalekar AD, Schonland SO, Kastritis E, et al. A European collaborative study of treatment outcomes in 346 patients with cardiac stage III AL amyloidosis. Blood. 2013;121(17):3420-3427.
    • (2013) Blood , vol.121 , Issue.17 , pp. 3420-3427
    • Wechalekar, A.D.1    Schonland, S.O.2    Kastritis, E.3
  • 30
    • 78149291059 scopus 로고    scopus 로고
    • The combination of high-sensitivity cardiac troponin T (hs-cTnT) at presentation and changes in N-terminal natriuretic peptide type B (NT-proBNP) after chemotherapy best predicts survival in AL amyloidosis
    • Palladini G, Barassi A, Klersy C, et al. The combination of high-sensitivity cardiac troponin T (hs-cTnT) at presentation and changes in N-terminal natriuretic peptide type B (NT-proBNP) after chemotherapy best predicts survival in AL amyloidosis. Blood. 2010;116(18):3426-3430.
    • (2010) Blood , vol.116 , Issue.18 , pp. 3426-3430
    • Palladini, G.1    Barassi, A.2    Klersy, C.3
  • 31
    • 77957735365 scopus 로고    scopus 로고
    • Assessment of disease severity and outcome in patients with systemic light-chain amyloidosis by the high-sensitivity troponin T assay
    • Kristen AV, Giannitsis E, Lehrke S, et al. Assessment of disease severity and outcome in patients with systemic light-chain amyloidosis by the high-sensitivity troponin T assay. Blood. 2010; 116(14):2455-2461.
    • (2010) Blood , vol.116 , Issue.14 , pp. 2455-2461
    • Kristen, A.V.1    Giannitsis, E.2    Lehrke, S.3
  • 32
    • 33645748052 scopus 로고    scopus 로고
    • Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation
    • Dispenzieri A, Lacy MQ, Katzmann JA, et al. Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation. Blood. 2006;107(8): 3378-3383.
    • (2006) Blood , vol.107 , Issue.8 , pp. 3378-3383
    • Dispenzieri, A.1    Lacy, M.Q.2    Katzmann, J.A.3
  • 33
    • 84979667499 scopus 로고    scopus 로고
    • High early mortality and poor outcomes for patients with AL amyloidosis presenting with high serum free light chains - A new risk stratification model [abstract]
    • Abstract 0544
    • Wechalekar AD, Wassef N, Lachmann H, et al. High early mortality and poor outcomes for patients with AL amyloidosis presenting with high serum free light chains - a new risk stratification model [abstract]. Haematologica. 2009;94(suppl 2): 222. Abstract 0544.
    • (2009) Haematologica , vol.94 SUPPL. 2 , pp. 222
    • Wechalekar, A.D.1    Wassef, N.2    Lachmann, H.3
  • 34
    • 84860643971 scopus 로고    scopus 로고
    • Revised prognostic staging system for light chain amyloidosis incorporating cardiac biomarkers and serum free light chain measurements
    • Kumar S, Dispenzieri A, Lacy MQ, et al. Revised prognostic staging system for light chain amyloidosis incorporating cardiac biomarkers and serum free light chain measurements. J Clin Oncol. 2012;30(9):989-995.
    • (2012) J Clin Oncol , vol.30 , Issue.9 , pp. 989-995
    • Kumar, S.1    Dispenzieri, A.2    Lacy, M.Q.3
  • 35
    • 84859923501 scopus 로고    scopus 로고
    • Best use of cardiac biomarkers in patients with AL amyloidosis and renal failure
    • Palladini G, Foli A, Milani P, et al. Best use of cardiac biomarkers in patients with AL amyloidosis and renal failure. Am J Hematol. 2012;87(5):465-471.
    • (2012) Am J Hematol , vol.87 , Issue.5 , pp. 465-471
    • Palladini, G.1    Foli, A.2    Milani, P.3
  • 36
    • 79953818145 scopus 로고    scopus 로고
    • Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14)
    • Bochtler T, Hegenbart U, Heiss C, et al. Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14). Blood. 2011;117(14):3809-3815.
    • (2011) Blood , vol.117 , Issue.14 , pp. 3809-3815
    • Bochtler, T.1    Hegenbart, U.2    Heiss, C.3
  • 37
    • 84885660451 scopus 로고    scopus 로고
    • Patients with immunoglobulin light chain amyloidosis undergoing autologous stem cell transplantation have superior outcomes compared with patients with multiple myeloma: A retrospective review from a tertiary referral center
    • Epub ahead of print
    • Dispenzieri A, Seenithamby K, Lacy MQ, et al. Patients with immunoglobulin light chain amyloidosis undergoing autologous stem cell transplantation have superior outcomes compared with patients with multiple myeloma: a retrospective review from a tertiary referral center. Bone Marrow Transplant. 2013 [Epub ahead of print]
    • (2013) Bone Marrow Transplant
    • Dispenzieri, A.1    Seenithamby, K.2    Lacy, M.Q.3
  • 38
    • 84871772553 scopus 로고    scopus 로고
    • New criteria for response to treatment in immunoglobulin light chain amyloidosis based on free light chain measurement and cardiac biomarkers: Impact on survival outcomes
    • Palladini G, Dispenzieri A, Gertz MA, et al. New criteria for response to treatment in immunoglobulin light chain amyloidosis based on free light chain measurement and cardiac biomarkers: impact on survival outcomes. J Clin Oncol. 2012;30(36):4541-4549.
    • (2012) J Clin Oncol , vol.30 , Issue.36 , pp. 4541-4549
    • Palladini, G.1    Dispenzieri, A.2    Gertz, M.A.3
  • 39
    • 77957690324 scopus 로고    scopus 로고
    • Discordance between serum cardiac biomarker and immunoglobulin-free light-chain response in patients with immunoglobulin light-chain amyloidosis treated with immune modulatory drugs
    • Dispenzieri A, Dingli D, Kumar SK, et al. Discordance between serum cardiac biomarker and immunoglobulin-free light-chain response in patients with immunoglobulin light-chain amyloidosis treated with immune modulatory drugs. Am J Hematol. 2010;85(10):757-759.
    • (2010) Am J Hematol , vol.85 , Issue.10 , pp. 757-759
    • Dispenzieri, A.1    Dingli, D.2    Kumar, S.K.3
  • 40
    • 79952139728 scopus 로고    scopus 로고
    • Outcome in renal Al amyloidosis after chemotherapy
    • Pinney JH, Lachmann HJ, Bansi L, et al. Outcome in renal Al amyloidosis after chemotherapy. J Clin Oncol. 2011;29(6):674-681.
    • (2011) J Clin Oncol , vol.29 , Issue.6 , pp. 674-681
    • Pinney, J.H.1    Lachmann, H.J.2    Bansi, L.3
  • 41
    • 78650073315 scopus 로고    scopus 로고
    • Autologous stem cell transplant for immunoglobulin light chain amyloidosis: A status report
    • Gertz MA, Lacy MQ, Dispenzieri A, et al. Autologous stem cell transplant for immunoglobulin light chain amyloidosis: a status report. Leuk Lymphoma. 2010;51(12):2181-2187.
    • (2010) Leuk Lymphoma , vol.51 , Issue.12 , pp. 2181-2187
    • Gertz, M.A.1    Lacy, M.Q.2    Dispenzieri, A.3
  • 42
    • 34548716992 scopus 로고    scopus 로고
    • Myélome Autogreffe (MAG) and Intergroupe Francophone du Myélome (IFM) Intergroup. High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis
    • Jaccard A, Moreau P, Leblond V, et al; Myélome Autogreffe (MAG) and Intergroupe Francophone du Myélome (IFM) Intergroup. High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis. N Engl J Med. 2007;357(11):1083-1093.
    • (2007) N Engl J Med , vol.357 , Issue.11 , pp. 1083-1093
    • Jaccard, A.1    Moreau, P.2    Leblond, V.3
  • 43
    • 84876420384 scopus 로고    scopus 로고
    • Refinement in patient selection to reduce treatment-related mortality from autologous stem cell transplantation in amyloidosis
    • Gertz MA, Lacy MQ, Dispenzieri A, et al. Refinement in patient selection to reduce treatment-related mortality from autologous stem cell transplantation in amyloidosis. Bone Marrow Transplant. 2013;48(4):557-561.
    • (2013) Bone Marrow Transplant , vol.48 , Issue.4 , pp. 557-561
    • Gertz, M.A.1    Lacy, M.Q.2    Dispenzieri, A.3
  • 44
    • 67549086765 scopus 로고    scopus 로고
    • Improvement of long-term survival after highdose melphalan in patients with light chain amyloidosis responding to induction chemotherapy [abstract]
    • Abstract 3334
    • Mangatter A, Schoenland SO, Hansberg M, et al. Improvement of long-term survival after highdose melphalan in patients with light chain amyloidosis responding to induction chemotherapy [abstract]. Blood. 2008;112(11). Abstract 3334.
    • (2008) Blood , vol.112 , Issue.11
    • Mangatter, A.1    Schoenland, S.O.2    Hansberg, M.3
  • 45
    • 80054844341 scopus 로고    scopus 로고
    • Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: Long-term results in a series of 421 patients
    • Cibeira MT, Sanchorawala V, Seldin DC, et al. Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients. Blood. 2011;118(16):4346-4352.
    • (2011) Blood , vol.118 , Issue.16 , pp. 4346-4352
    • Cibeira, M.T.1    Sanchorawala, V.2    Seldin, D.C.3
  • 46
    • 79952005272 scopus 로고    scopus 로고
    • Transplantation vs. Conventional-dose therapy for amyloidosis
    • Palladini G, Merlini G. Transplantation vs. conventional-dose therapy for amyloidosis. Curr Opin Oncol. 2011;23(2):214-220.
    • (2011) Curr Opin Oncol , vol.23 , Issue.2 , pp. 214-220
    • Palladini, G.1    Merlini, G.2
  • 48
    • 84876120242 scopus 로고    scopus 로고
    • Bortezomib and dexamethasone consolidation following risk-adapted melphalan and stem cell transplantation for patients with newly diagnosed light-chain amyloidosis
    • Landau H, Hassoun H, Rosenzweig MA, et al. Bortezomib and dexamethasone consolidation following risk-adapted melphalan and stem cell transplantation for patients with newly diagnosed light-chain amyloidosis. Leukemia. 2013;27(4): 823-828.
    • (2013) Leukemia , vol.27 , Issue.4 , pp. 823-828
    • Landau, H.1    Hassoun, H.2    Gertz, M.A.3
  • 49
    • 84890569032 scopus 로고    scopus 로고
    • Longterm outcomes of patients with systemic light Comenzo RL, Fein DE, Hassoun H, et al. Longterm outcomes of patients with systemic light chain amyloidosis (AL) treated at diagnosis with risk-adapted stem cell transplant and consolidation with novel agents [abstract]
    • Abstract 3150
    • Comenzo RL, Fein DE, Hassoun H, et al. Longtermoutcomes of patients with systemic light chain amyloidosis (AL) treated at diagnosis with risk-adapted stem cell transplant and consolidation with novel agents [abstract]. Blood.2012;120(21). Abstract 3150.
    • (2012) Blood , vol.120 , Issue.21
    • Comenzo, R.L.1    Fein, D.E.2    Hassoun, H.3
  • 50
    • 84860897399 scopus 로고    scopus 로고
    • Cyclophosphamide, bortezomib, and dexamethasone therapy in AL amyloidosis is associated with high clonal response rates and prolonged progression-free survival
    • Venner CP, Lane T, Foard D, et al. Cyclophosphamide, bortezomib, and dexamethasone therapy in AL amyloidosis is associated with high clonal response rates and prolonged progression-free survival. Blood. 2012; 119(19):4387-4390.
    • (2012) Blood , vol.119 , Issue.19 , pp. 4387-4390
    • Venner, C.P.1    Lane, T.2    Foard, D.3
  • 51
    • 84860898706 scopus 로고    scopus 로고
    • Cyclophosphamide-bortezomibdexamethasone (CyBorD) produces rapid and complete hematologic response in patients with AL amyloidosis
    • Mikhael JR, Schuster SR, Jimenez-Zepeda VH, et al. Cyclophosphamide- bortezomibdexamethasone (CyBorD) produces rapid and complete hematologic response in patients with AL amyloidosis. Blood. 2012;119(19):4391-4394.
    • (2012) Blood , vol.119 , Issue.19 , pp. 4391-4394
    • Mikhael, J.R.1    Schuster, S.R.2    Jimenez-Zepeda, V.H.3
  • 52
    • 77956051099 scopus 로고    scopus 로고
    • Treatment with intravenous melphalan and dexamethasone is not able to overcome the poor prognosis of patients with newly diagnosed systemic light chain amyloidosis and severe cardiac involvement
    • Dietrich S, Schönland SO, Benner A, et al. Treatment with intravenous melphalan and dexamethasone is not able to overcome the poor prognosis of patients with newly diagnosed systemic light chain amyloidosis and severe cardiac involvement. Blood. 2010;116(4): 522-528.
    • (2010) Blood , vol.116 , Issue.4 , pp. 522-528
    • Dietrich, S.1    Schönland, S.O.2    Benner, A.3
  • 53
    • 36348934009 scopus 로고    scopus 로고
    • Bortezomib in the treatment of AL amyloidosis: Targeted therapy?
    • DOI 10.3324/haematol.12136
    • Sitia R, Palladini G, Merlini G. Bortezomib in the treatment of AL amyloidosis: targeted therapy? Haematologica. 2007;92(10):1302-1307. (Pubitemid 350144146)
    • (2007) Haematologica , vol.92 , Issue.10 , pp. 1302-1307
    • Sitia, R.1    Palladini, G.2    Merlini, G.3
  • 54
    • 79952003103 scopus 로고    scopus 로고
    • Proteasome activity and stress in light chain amyloidosis [abstract]
    • Abstract OP-043
    • Oliva L, Pengo N, Palladini G, et al. Proteasome activity and stress in light chain amyloidosis [abstract]. Amyloid. 2010;17(suppl 1):99. Abstract OP-043.
    • (2010) Amyloid , vol.17 , Issue.SUPPL. 1 , pp. 99
    • Oliva, L.1    Pengo, N.2    Palladini, G.3
  • 55
    • 11144358046 scopus 로고    scopus 로고
    • Association of melphalan and high-dose dexamethasone is effective and well tolerated in patients with AL (primary) amyloidosis who are ineligible for stem cell transplantation
    • DOI 10.1182/blood-2003-08-2788
    • Palladini G, Perfetti V, Obici L, et al. Association of melphalan and high-dose dexamethasone is effective and well tolerated in patients with AL (primary) amyloidosis who are ineligible for stem cell transplantation. Blood. 2004;103(8): 2936-2938. (Pubitemid 38451663)
    • (2004) Blood , vol.103 , Issue.8 , pp. 2936-2938
    • Palladini, G.1    Perfetti, V.2    Obici, L.3    Caccialanza, R.4    Semino, A.5    Adami, F.6    Cavallero, G.7    Rustichelli, R.8    Virga, G.9    Merlini, G.10
  • 56
    • 34547137414 scopus 로고    scopus 로고
    • Treatment with oral melphalan plus dexamethasone produces long-term remissions in AL amyloidosis
    • DOI 10.1182/blood-2007-02-076034
    • Palladini G, Russo P, Nuvolone M, et al. Treatment with oral melphalan plus dexamethasone produces long-term remissions in AL amyloidosis. Blood. 2007;110(2):787-788. (Pubitemid 47105419)
    • (2007) Blood , vol.110 , Issue.2 , pp. 787-788
    • Palladini, G.1    Russo, P.2    Nuvolone, M.3    Lavatelli, F.4    Perfetti, V.5    Obici, L.6    Merlini, G.7
  • 57
    • 33846263334 scopus 로고    scopus 로고
    • Safety and efficacy of risk-adapted cyclophosphamide, thalidomide, and dexamethasone in systemic AL amyloidosis
    • DOI 10.1182/blood-2006-07-035352
    • Wechalekar AD, Goodman HJ, Lachmann HJ, Offer M, Hawkins PN, Gillmore JD. Safety and efficacy of risk-adapted cyclophosphamide, thalidomide, and dexamethasone in systemic AL amyloidosis. Blood. 2007;109(2):457-464. (Pubitemid 46105938)
    • (2007) Blood , vol.109 , Issue.2 , pp. 457-464
    • Wechalekar, A.D.1    Goodman, H.J.B.2    Lachmann, H.J.3    Offer, M.4    Hawkins, P.N.5    Gillmore, J.D.6
  • 58
    • 77951626820 scopus 로고    scopus 로고
    • Short and long-term outcome of treatment with high-dose melphalan and stem cell transplantation for multiple myeloma-associated AL amyloidosis
    • Girnius S, Seldin DC, Skinner M, et al. Short and long-term outcome of treatment with high-dose melphalan and stem cell transplantation for multiple myeloma-associated AL amyloidosis. Ann Hematol. 2010;89(6):579-584.
    • (2010) Ann Hematol , vol.89 , Issue.6 , pp. 579-584
    • Girnius, S.1    Seldin, D.C.2    Skinner, M.3
  • 59
    • 77949897868 scopus 로고    scopus 로고
    • Bortezomib with or without dexamethasone in primary systemic (light chain) amyloidosis
    • Kastritis E, Wechalekar AD, Dimopoulos MA, et al. Bortezomib with or without dexamethasone in primary systemic (light chain) amyloidosis. J Clin Oncol. 2010;28(6):1031-1037.
    • (2010) J Clin Oncol , vol.28 , Issue.6 , pp. 1031-1037
    • Kastritis, E.1    Wechalekar, A.D.2    Dimopoulos, M.A.3
  • 60
    • 79960934028 scopus 로고    scopus 로고
    • Efficacy and safety of once-weekly and twice-weekly bortezomib in patients with relapsed systemic AL amyloidosis: Results of a phase 1/2 study
    • Reece DE, Hegenbart U, Sanchorawala V, et al. Efficacy and safety of once-weekly and twice-weekly bortezomib in patients with relapsed systemic AL amyloidosis: results of a phase 1/2 study. Blood. 2011;118(4):865-873.
    • (2011) Blood , vol.118 , Issue.4 , pp. 865-873
    • Reece, D.E.1    Hegenbart, U.2    Sanchorawala, V.3
  • 62
    • 84857087905 scopus 로고    scopus 로고
    • Salvage therapy with lenalidomide and dexamethasone in patients with advanced AL amyloidosis refractory to melphalan, bortezomib, and thalidomide
    • Palladini G, Russo P, Foli A, et al. Salvage therapy with lenalidomide and dexamethasone in patients with advanced AL amyloidosis refractory to melphalan, bortezomib, and thalidomide. Ann Hematol. 2012;91(1):89-92.
    • (2012) Ann Hematol , vol.91 , Issue.1 , pp. 89-92
    • Palladini, G.1    Russo, P.2    Foli, A.3
  • 63
    • 84862512160 scopus 로고    scopus 로고
    • Activity of pomalidomide in patients with immunoglobulin lightchain amyloidosis
    • Dispenzieri A, Buadi F, Laumann K, et al. Activity of pomalidomide in patients with immunoglobulin lightchain amyloidosis. Blood. 2012;119(23):5397- 5404.
    • (2012) Blood , vol.119 , Issue.23 , pp. 5397-5404
    • Dispenzieri, A.1    Buadi, F.2    Laumann, K.3
  • 65
    • 79952126085 scopus 로고    scopus 로고
    • Kidney dysfunction during lenalidomide treatment for AL amyloidosis
    • Specter R, Sanchorawala V, Seldin DC, et al. Kidney dysfunction during lenalidomide treatment for AL amyloidosis. Nephrol Dial Transplant. 2011;26(3):881-886.
    • (2011) Nephrol Dial Transplant , vol.26 , Issue.3 , pp. 881-886
    • Specter, R.1    Sanchorawala, V.2    Seldin, D.C.3
  • 66
    • 84861521224 scopus 로고    scopus 로고
    • Lenalidomide, cyclophosphamide, and dexamethasone (CRd) for light-chain amyloidosis: Long-term results from a phase 2 trial
    • Kumar SK, Hayman SR, Buadi FK, et al. Lenalidomide, cyclophosphamide, and dexamethasone (CRd) for light-chain amyloidosis: long-term results from a phase 2 trial. Blood. 2012;119(21):4860-4867.
    • (2012) Blood , vol.119 , Issue.21 , pp. 4860-4867
    • Kumar, S.K.1    Hayman, S.R.2    Buadi, F.K.3
  • 67
    • 84862551010 scopus 로고    scopus 로고
    • A phase 1/2 study of lenalidomide with low-dose oral cyclophosphamide and low-dose dexamethasone (RdC) in AL amyloidosis
    • Kastritis E, Terpos E, Roussou M, et al. A phase 1/2 study of lenalidomide with low-dose oral cyclophosphamide and low-dose dexamethasone (RdC) in AL amyloidosis. Blood. 2012;119(23): 5384-5390.
    • (2012) Blood , vol.119 , Issue.23 , pp. 5384-5390
    • Kastritis, E.1    Terpos, E.2    Roussou, M.3
  • 68
    • 84874549558 scopus 로고    scopus 로고
    • A phase II trial of cyclophosphamide, lenalidomide and dexamethasone in previously treated patients with AL amyloidosis
    • Palladini G, Russo P, Milani P, et al. A phase II trial of cyclophosphamide, lenalidomide and dexamethasone in previously treated patients with AL amyloidosis. Haematologica. 2013;98(3):433-436.
    • (2013) Haematologica , vol.98 , Issue.3 , pp. 433-436
    • Palladini, G.1    Russo, P.2    Milani, P.3
  • 69
    • 78649759752 scopus 로고    scopus 로고
    • Lenalidomide in combination with melphalan and dexamethasone in patients with newly diagnosed AL amyloidosis: A multicenter phase 1/2 doseescalation study
    • Moreau P, Jaccard A, Benboubker L, et al. Lenalidomide in combination with melphalan and dexamethasone in patients with newly diagnosed AL amyloidosis: a multicenter phase 1/2 doseescalation study. Blood. 2010;116(23): 4777-4782.
    • (2010) Blood , vol.116 , Issue.23 , pp. 4777-4782
    • Moreau, P.1    Jaccard, A.2    Benboubker, L.3
  • 70
    • 84877063628 scopus 로고    scopus 로고
    • Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: Results of a phase II trial
    • Sanchorawala V, Patel JM, Sloan JM, Shelton AC, Zeldis JB, Seldin DC. Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: results of a phase II trial. Haematologica. 2013;98(5):789-792.
    • (2013) Haematologica , vol.98 , Issue.5 , pp. 789-792
    • Sanchorawala, V.1    Patel, J.M.2    Sloan, J.M.3    Shelton, A.C.4    Zeldis, J.B.5    Seldin, D.C.6
  • 71
    • 84890937654 scopus 로고    scopus 로고
    • MLN9708, a novel, investigational oral proteasome inhibitor, in patients with relapsed or refractory light-chain amyloidosis (AL): Results of a phase 1 study [abstract]
    • Abstract 731
    • Merlini G, Sanchorawala V, Zonder JA, et al. MLN9708, a novel, investigational oral proteasome inhibitor, in patients with relapsed or refractory light-chain amyloidosis (AL): results of a phase 1 study [abstract]. Blood. 2012;120(21). Abstract 731.
    • (2012) Blood , vol.120 , Issue.21
    • Merlini, G.1    Sanchorawala, V.2    Zonder, J.A.3
  • 72
    • 84947486659 scopus 로고    scopus 로고
    • Treatment of AL amyloidosis with bendamustine [abstract]
    • Abstract 4057
    • Palladini G, Schonland SO, Milani P, et al. Treatment of AL amyloidosis with bendamustine [abstract]. Blood. 2012;120(21). Abstract 4057.
    • (2012) Blood , vol.120 , Issue.21
    • Palladini, G.1    Schonland, S.O.2    Milani, P.3
  • 73
    • 84887859910 scopus 로고    scopus 로고
    • Systemic amyloidoses: What an internist should know
    • In press
    • Palladini G, Merlini G. Systemic amyloidoses: what an internist should know. Eur J Intern Med. In press.
    • Eur J Intern Med.
    • Palladini, G.1    Merlini, G.2
  • 75
    • 38349057368 scopus 로고    scopus 로고
    • Treatment options for severe cardiac amyloidosis: Heart transplantation combined with chemotherapy and stem cell transplantation for patients with AL-amyloidosis and heart and liver transplantation for patients with ATTRamyloidosis
    • Sack FU, Kristen A, Goldschmidt H, et al. Treatment options for severe cardiac amyloidosis: heart transplantation combined with chemotherapy and stem cell transplantation for patients with AL-amyloidosis and heart and liver transplantation for patients with ATTRamyloidosis. Eur J Cardiothorac Surg. 2008;33(2): 257-262.
    • (2008) Eur J Cardiothorac Surg , vol.33 , Issue.2 , pp. 257-262
    • Sack, F.U.1    Kristen, A.2    Goldschmidt, H.3
  • 76
    • 47749109821 scopus 로고    scopus 로고
    • Autologous stem cell transplant after heart transplant for light chain (Al) amyloid cardiomyopathy
    • Lacy MQ, Dispenzieri A, Hayman SR, et al. Autologous stem cell transplant after heart transplant for light chain (Al) amyloid cardiomyopathy. J Heart Lung Transplant. 2008; 27(8):823-829.
    • (2008) J Heart Lung Transplant , vol.27 , Issue.8 , pp. 823-829
    • Lacy, M.Q.1    Dispenzieri, A.2    Hayman, S.R.3
  • 77
    • 78249290790 scopus 로고    scopus 로고
    • Cardiac transplantation followed by dose-intensive melphalan and autologous stem-cell transplantation for light chain amyloidosis and heart failure
    • Dey BR, Chung SS, Spitzer TR, et al. Cardiac transplantation followed by dose-intensive melphalan and autologous stem-cell transplantation for light chain amyloidosis and heart failure. Transplantation. 2010;90(8): 905-911.
    • (2010) Transplantation , vol.90 , Issue.8 , pp. 905-911
    • Dey, B.R.1    Chung, S.S.2    Spitzer, T.R.3
  • 79
    • 84869081202 scopus 로고    scopus 로고
    • Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis
    • Comenzo RL, Reece D, Palladini G, et al. Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis. Leukemia. 2012;26(11): 2317-2325.
    • (2012) Leukemia , vol.26 , Issue.11 , pp. 2317-2325
    • Comenzo, R.L.1    Reece, D.2    Palladini, G.3
  • 80
    • 78149282151 scopus 로고    scopus 로고
    • Antibodies to human serum amyloid P component eliminate visceral amyloid deposits
    • Bodin K, Ellmerich S, Kahan MC, et al. Antibodies to human serum amyloid P component eliminate visceral amyloid deposits. Nature. 2010; 468(7320):93-97.
    • (2010) Nature , vol.468 , Issue.7320 , pp. 93-97
    • Bodin, K.1    Ellmerich, S.2    Kahan, M.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.