메뉴 건너뛰기




Volumn 109, Issue 2, 2007, Pages 457-464

Safety and efficacy of risk-adapted cyclophosphamide, thalidomide, and dexamethasone in systemic AL amyloidosis

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; DEXAMETHASONE; MELPHALAN; PREDNISOLONE; THALIDOMIDE;

EID: 33846263334     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-07-035352     Document Type: Article
Times cited : (211)

References (40)
  • 1
    • 0026519157 scopus 로고
    • Incidence and natural history of primary systemic amyloidosis in Olmsted County, Minnesota, 1950 through 1989
    • Kyle RA, Linos A, Beard CM, et al. Incidence and natural history of primary systemic amyloidosis in Olmsted County, Minnesota, 1950 through 1989. Blood. 1992;79:1817-1822.
    • (1992) Blood , vol.79 , pp. 1817-1822
    • Kyle, R.A.1    Linos, A.2    Beard, C.M.3
  • 2
    • 0030895545 scopus 로고    scopus 로고
    • A trial of three regimens for primary amyloidosis: Colchicine alone, melphalan and prednisone, and melphalan, prednisone, and colchicine
    • Kyle RA, Gertz MA, Greipp PR, et al. A trial of three regimens for primary amyloidosis: colchicine alone, melphalan and prednisone, and melphalan, prednisone, and colchicine. N Engl J Med. 1997;336:1202-1207.
    • (1997) N Engl J Med , vol.336 , pp. 1202-1207
    • Kyle, R.A.1    Gertz, M.A.2    Greipp, P.R.3
  • 3
    • 0032525180 scopus 로고    scopus 로고
    • Doseintensive melphalan with blood stem-cell support for the treatment of AL (amyloid light-chain) amyloidosis: Survival and responses in 25 patients
    • Comenzo RL, Vosburgh E, Falk RH, et al. Doseintensive melphalan with blood stem-cell support for the treatment of AL (amyloid light-chain) amyloidosis: survival and responses in 25 patients. Blood. 1998;91:3662-3670.
    • (1998) Blood , vol.91 , pp. 3662-3670
    • Comenzo, R.L.1    Vosburgh, E.2    Falk, R.H.3
  • 4
    • 0037097843 scopus 로고    scopus 로고
    • Autologous stem cell transplantation for primary systemic amyloidosis
    • Comenzo RL, Gertz MA. Autologous stem cell transplantation for primary systemic amyloidosis. Blood. 2002;99:4276-4282.
    • (2002) Blood , vol.99 , pp. 4276-4282
    • Comenzo, R.L.1    Gertz, M.A.2
  • 5
    • 33846249725 scopus 로고    scopus 로고
    • Clonal diseases response and clinical outcome in 229 patients with AL amyloidosis treated with VAD-like chemotherapy [abstract]
    • Goodman H, Wechalekar A, Lachmann H, Bradwell A, Hawkins P. Clonal diseases response and clinical outcome in 229 patients with AL amyloidosis treated with VAD-like chemotherapy [abstract]. Haematologica. 2005;90:201.
    • (2005) Haematologica , vol.90 , pp. 201
    • Goodman, H.1    Wechalekar, A.2    Lachmann, H.3    Bradwell, A.4    Hawkins, P.5
  • 6
    • 32944455916 scopus 로고    scopus 로고
    • Intermediate dose intravenous melphalan and dexamethasone treatment in 144 patients with systemic AL amyloidosis [abstract]
    • Goodman HJB, Lachmann HJ, Bradwell AR, Hawkins PN. Intermediate dose intravenous melphalan and dexamethasone treatment in 144 patients with systemic AL amyloidosis [abstract]. Blood. 2004;104:755.
    • (2004) Blood , vol.104 , pp. 755
    • Goodman, H.J.B.1    Lachmann, H.J.2    Bradwell, A.R.3    Hawkins, P.N.4
  • 7
    • 11144358046 scopus 로고    scopus 로고
    • Association of melphalan and high-dose dexamethasone is effective and well tolerated in patients with AL (primary) amyloidosis who are ineligible for stem cell transplantation
    • Palladini G, Perfetti V, Obici L, et al. Association of melphalan and high-dose dexamethasone is effective and well tolerated in patients with AL (primary) amyloidosis who are ineligible for stem cell transplantation. Blood. 2004;103:2936-2938.
    • (2004) Blood , vol.103 , pp. 2936-2938
    • Palladini, G.1    Perfetti, V.2    Obici, L.3
  • 8
  • 9
    • 1642421878 scopus 로고    scopus 로고
    • Poor tolerance to high doses of thalidomide in patients with primary systemic amyloidosis
    • Dispenzieri A, Lacy MQ, Rajkumar SV, et al. Poor tolerance to high doses of thalidomide in patients with primary systemic amyloidosis. Amyloid. 2003;10:257-261.
    • (2003) Amyloid , vol.10 , pp. 257-261
    • Dispenzieri, A.1    Lacy, M.Q.2    Rajkumar, S.V.3
  • 10
    • 0037359277 scopus 로고    scopus 로고
    • Tolerability and efficacy of thalidomide for the treatment of patients with light chain-associated (AL) amyloidosis
    • Seldin DC, Choufani EB, Dember LM, et al. Tolerability and efficacy of thalidomide for the treatment of patients with light chain-associated (AL) amyloidosis. Clin Lymphoma. 2003;3:241-246.
    • (2003) Clin Lymphoma , vol.3 , pp. 241-246
    • Seldin, D.C.1    Choufani, E.B.2    Dember, L.M.3
  • 11
    • 33846246151 scopus 로고    scopus 로고
    • Low dose single agent thalidomide is tolerated in patients with primary systemic amyloidosis, but responses are limited [abstract]
    • Dispenzieri A, Lacy MQ, Geyer SM, et al. Low dose single agent thalidomide is tolerated in patients with primary systemic amyloidosis, but responses are limited [abstract]. Blood. 2004;104:4920.
    • (2004) Blood , vol.104 , pp. 4920
    • Dispenzieri, A.1    Lacy, M.Q.2    Geyer, S.M.3
  • 12
    • 15944395687 scopus 로고    scopus 로고
    • The combination of thalidomide and intermediate-dose dexamethasone is an effective but toxic treatment for patients with primary amyloidosis (AL)
    • Palladini G, Perfetti V, Perlini S, et al. The combination of thalidomide and intermediate-dose dexamethasone is an effective but toxic treatment for patients with primary amyloidosis (AL). Blood. 2005;105:2949-2951.
    • (2005) Blood , vol.105 , pp. 2949-2951
    • Palladini, G.1    Perfetti, V.2    Perlini, S.3
  • 13
    • 11144356289 scopus 로고    scopus 로고
    • Pulsed cyclophosphamide, thalidomide and dexamethasone: An oral regimen for previously treated patients with multiple myeloma
    • Dimopoulos MA, Hamilos G, Zomas A, et al. Pulsed cyclophosphamide, thalidomide and dexamethasone: an oral regimen for previously treated patients with multiple myeloma. Hematol J. 2004;5:112-117.
    • (2004) Hematol J , vol.5 , pp. 112-117
    • Dimopoulos, M.A.1    Hamilos, G.2    Zomas, A.3
  • 14
    • 85047682765 scopus 로고    scopus 로고
    • The combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is feasible and can be an option for relapsed/refractory multiple myeloma
    • Garcia-Sanz R, Gonzalez-Fraile MI, Sierra M, Lopez C, Gonzalez M, San Miguel JF. The combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is feasible and can be an option for relapsed/refractory multiple myeloma. Hematol J. 2002;3:43-48.
    • (2002) Hematol J , vol.3 , pp. 43-48
    • Garcia-Sanz, R.1    Gonzalez-Fraile, M.I.2    Sierra, M.3    Lopez, C.4    Gonzalez, M.5    San Miguel, J.F.6
  • 15
    • 3042685387 scopus 로고    scopus 로고
    • Guidelines on the diagnosis and management of AL amyloidosis
    • Guidelines Working Group of UK Myeloma Forum, British Committee for Standards in Haematology, British Society for Haematology
    • Guidelines Working Group of UK Myeloma Forum, British Committee for Standards in Haematology, British Society for Haematology. Guidelines on the diagnosis and management of AL amyloidosis. Br J Haematol. 2004;125:681-700.
    • (2004) Br J Haematol , vol.125 , pp. 681-700
  • 16
    • 0037030659 scopus 로고    scopus 로고
    • Misdiagnosis of hereditary amyloidosis as AL (primary) amyloidosis
    • Lachmann HJ, Booth DR, Booth SE, et al. Misdiagnosis of hereditary amyloidosis as AL (primary) amyloidosis. N Engl J Med. 2002;346:1786-1791.
    • (2002) N Engl J Med , vol.346 , pp. 1786-1791
    • Lachmann, H.J.1    Booth, D.R.2    Booth, S.E.3
  • 17
    • 0038345324 scopus 로고    scopus 로고
    • Outcome in systemic AL amyloidosis in relation to changes in concentration of circulating free immunoglobulin light chains following chemotherapy
    • Lachmann HJ, Gallimore R, Gillmore JD, et al. Outcome in systemic AL amyloidosis in relation to changes in concentration of circulating free immunoglobulin light chains following chemotherapy. Br J Haematol. 2003;122:78-84.
    • (2003) Br J Haematol , vol.122 , pp. 78-84
    • Lachmann, H.J.1    Gallimore, R.2    Gillmore, J.D.3
  • 19
    • 18244428600 scopus 로고    scopus 로고
    • Criteria for evaluating disease response and progression in patients with multiple myeloma treated by highdose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant
    • Blade J, Samson D, Reece D, et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by highdose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Br J Haematol. 1998;102:1115-1123.
    • (1998) Br J Haematol , vol.102 , pp. 1115-1123
    • Blade, J.1    Samson, D.2    Reece, D.3
  • 20
    • 0036720993 scopus 로고    scopus 로고
    • Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: Relative sensitivity for detection of monoclonal light chains
    • Katzmann JA, Clark RJ, Abraham RS, et al. Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains. Clin Chem. 2002;48:1437-1444.
    • (2002) Clin Chem , vol.48 , pp. 1437-1444
    • Katzmann, J.A.1    Clark, R.J.2    Abraham, R.S.3
  • 21
    • 84888750369 scopus 로고    scopus 로고
    • Cancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 3.0. Accessed online August 2006
    • Cancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 3.0. Accessed online August 2006.
  • 23
    • 0020396015 scopus 로고
    • Toxicity and response criteria of the Eastern Cooperative Oncology Group
    • Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982;5:649-655.
    • (1982) Am J Clin Oncol , vol.5 , pp. 649-655
    • Oken, M.M.1    Creech, R.H.2    Tormey, D.C.3
  • 24
    • 0025025397 scopus 로고
    • Evaluation of systemic amyloidosis by scintigraphy with 123I-labeled serum amyloid P component
    • Hawkins PN, Lavender JP, Pepys MB. Evaluation of systemic amyloidosis by scintigraphy with 123I-labeled serum amyloid P component. N Engl J Med. 1990;323:508-513.
    • (1990) N Engl J Med , vol.323 , pp. 508-513
    • Hawkins, P.N.1    Lavender, J.P.2    Pepys, M.B.3
  • 25
    • 0035879128 scopus 로고    scopus 로고
    • Eligibility for hematopoietic stem-cell transplantation for primary systemic amyloidosis is a favorable prognostic factor for survival
    • Dispenzieri A, Lacy MQ, Kyle RA, et al. Eligibility for hematopoietic stem-cell transplantation for primary systemic amyloidosis is a favorable prognostic factor for survival. J Clin Oncol. 2001;19:3350-3356.
    • (2001) J Clin Oncol , vol.19 , pp. 3350-3356
    • Dispenzieri, A.1    Lacy, M.Q.2    Kyle, R.A.3
  • 26
    • 0026034817 scopus 로고
    • Response rates and survival in primary systemic amyloidosis
    • Gertz MA, Kyle RA, Greipp PR. Response rates and survival in primary systemic amyloidosis. Blood. 1991;77:257-262.
    • (1991) Blood , vol.77 , pp. 257-262
    • Gertz, M.A.1    Kyle, R.A.2    Greipp, P.R.3
  • 27
    • 2342591289 scopus 로고    scopus 로고
    • Superior survival in primary systemic amyloidosis patients undergoing peripheral blood stem cell transplantation: A case-control study
    • Dispenzieri A, Kyle RA, Lacy MQ, et al. Superior survival in primary systemic amyloidosis patients undergoing peripheral blood stem cell transplantation: a case-control study. Blood. 2004;103:3960-3963.
    • (2004) Blood , vol.103 , pp. 3960-3963
    • Dispenzieri, A.1    Kyle, R.A.2    Lacy, M.Q.3
  • 28
    • 30944433400 scopus 로고    scopus 로고
    • Serum free light-chain responses after high-dose intravenous melphalan and autologous stem cell transplantation for AL (primary) amyloidosis
    • Sanchorawala V, Seldin DC, Magnani B, Skinner M, Wright DG. Serum free light-chain responses after high-dose intravenous melphalan and autologous stem cell transplantation for AL (primary) amyloidosis. Bone Marrow Transplant. 2005;36:597-600.
    • (2005) Bone Marrow Transplant , vol.36 , pp. 597-600
    • Sanchorawala, V.1    Seldin, D.C.2    Magnani, B.3    Skinner, M.4    Wright, D.G.5
  • 29
    • 33645748052 scopus 로고    scopus 로고
    • Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation
    • Dispenzieri A, Lacy MQ, Katzmann JA, et al. Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation. Blood. 2006;107:3378-3383.
    • (2006) Blood , vol.107 , pp. 3378-3383
    • Dispenzieri, A.1    Lacy, M.Q.2    Katzmann, J.A.3
  • 30
    • 7144251173 scopus 로고    scopus 로고
    • Prognostic factors for survival and response after high-dose therapy and autologous stem cell transplantation in systemic AL amyloidosis: A report on 21 patients
    • Moreau P, Leblond V, Bourquelot P, et al. Prognostic factors for survival and response after high-dose therapy and autologous stem cell transplantation in systemic AL amyloidosis: a report on 21 patients. Br J Haematol. 1998;101:766-769.
    • (1998) Br J Haematol , vol.101 , pp. 766-769
    • Moreau, P.1    Leblond, V.2    Bourquelot, P.3
  • 31
    • 33644772521 scopus 로고    scopus 로고
    • Autologous stem cell transplantation (ASCT) versus oral melphalan and high-dose dexamethasone in patients with AL (Primary) amyloidosis: Results of the French Multicentric Randomized Trial (MAG and IFM Intergroup) [abstract]
    • Jaccard A, Moreau P, Leblond V, et al. Autologous stem cell transplantation (ASCT) versus oral melphalan and high-dose dexamethasone in patients with AL (Primary) amyloidosis: results of the French Multicentric Randomized Trial (MAG and IFM Intergroup) [abstract]. Blood. 2005;106:421.
    • (2005) Blood , vol.106 , pp. 421
    • Jaccard, A.1    Moreau, P.2    Leblond, V.3
  • 32
    • 9144269708 scopus 로고    scopus 로고
    • High-dose melphalan and autologous stem-cell transplantation in patients with AL amyloidosis: An 8-year study
    • Skinner M, Sanchorawala V, Seldin DC, et al. High-dose melphalan and autologous stem-cell transplantation in patients with AL amyloidosis: an 8-year study. Ann Intern Med. 2004;140:85-93.
    • (2004) Ann Intern Med , vol.140 , pp. 85-93
    • Skinner, M.1    Sanchorawala, V.2    Seldin, D.C.3
  • 33
    • 0032952933 scopus 로고    scopus 로고
    • Prospective randomized trial of melphalan and prednisone versus vincristine, carmustine, melphalan, cyclophosphamide, and prednisone in the treatment of primary systemic amyloidosis
    • Gertz MA, Lacy MQ, Lust JA, Greipp PR, Witzig TE, Kyle RA. Prospective randomized trial of melphalan and prednisone versus vincristine, carmustine, melphalan, cyclophosphamide, and prednisone in the treatment of primary systemic amyloidosis. J Clin Oncol. 1999;17:262-267.
    • (1999) J Clin Oncol , vol.17 , pp. 262-267
    • Gertz, M.A.1    Lacy, M.Q.2    Lust, J.A.3    Greipp, P.R.4    Witzig, T.E.5    Kyle, R.A.6
  • 34
    • 6044260269 scopus 로고    scopus 로고
    • Clinical efficacy of high-dose dexamethasone with maintenance dexamethasone/alpha interferon in patients with primary systemic amyloidosis: Results of United States Intergroup Trial Southwest Oncology Group (SWOG) S9628
    • Dhodapkar MV, Hussein MA, Rasmussen E, et al. Clinical efficacy of high-dose dexamethasone with maintenance dexamethasone/alpha interferon in patients with primary systemic amyloidosis: results of United States Intergroup Trial Southwest Oncology Group (SWOG) S9628. Blood. 2004;104:3520-3526.
    • (2004) Blood , vol.104 , pp. 3520-3526
    • Dhodapkar, M.V.1    Hussein, M.A.2    Rasmussen, E.3
  • 35
    • 28844472902 scopus 로고    scopus 로고
    • Lenalidomide and thalidomide: Mechanisms of action - similarities and differences
    • Anderson KC. Lenalidomide and thalidomide: mechanisms of action - similarities and differences. Semin Hematol. 2005;42(4 suppl 4):S3-S8.
    • (2005) Semin Hematol , vol.42 , Issue.4 SUPPL. 4
    • Anderson, K.C.1
  • 36
    • 0034885073 scopus 로고    scopus 로고
    • Thalidomide in the management of multiple myeloma
    • Barlogie B, Zangari M, Spencer T, et al. Thalidomide in the management of multiple myeloma. Semin Hematol. 2001;38:250-259.
    • (2001) Semin Hematol , vol.38 , pp. 250-259
    • Barlogie, B.1    Zangari, M.2    Spencer, T.3
  • 37
    • 33644831033 scopus 로고    scopus 로고
    • Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group
    • Rajkumar SV, Blood E, Vesole D, Fonseca R, Greipp PR. Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol. 2006;24:431-436.
    • (2006) J Clin Oncol , vol.24 , pp. 431-436
    • Rajkumar, S.V.1    Blood, E.2    Vesole, D.3    Fonseca, R.4    Greipp, P.R.5
  • 38
    • 33645504594 scopus 로고    scopus 로고
    • Total therapy 2 without thalidomide in comparison with total therapy 1: Role of intensified induction and posttransplantation consolidation therapies
    • Barlogie B, Tricot G, Rasmussen E, et al. Total therapy 2 without thalidomide in comparison with total therapy 1: role of intensified induction and posttransplantation consolidation therapies. Blood. 2006;107:2633-2638.
    • (2006) Blood , vol.107 , pp. 2633-2638
    • Barlogie, B.1    Tricot, G.2    Rasmussen, E.3
  • 39
    • 0347815503 scopus 로고    scopus 로고
    • Single versus double autologous stem-cell transplantation for multiple myeloma
    • Attal M, Harousseau JL, Facon T, et al. Single versus double autologous stem-cell transplantation for multiple myeloma. N Engl J Med. 2003;349:2495-2502.
    • (2003) N Engl J Med , vol.349 , pp. 2495-2502
    • Attal, M.1    Harousseau, J.L.2    Facon, T.3
  • 40
    • 33846199333 scopus 로고    scopus 로고
    • Newly diagnosed myeloma patients are at risk of venous thrombotic events - high risk patients need to be identified and receive thromboprophylaxis: The MRC Experience [abstract]
    • Davies FE, Child JA, Hawkins K, et al. Newly diagnosed myeloma patients are at risk of venous thrombotic events - high risk patients need to be identified and receive thromboprophylaxis: the MRC Experience [abstract]. Blood. 2004;104:2395.
    • (2004) Blood , vol.104 , pp. 2395
    • Davies, F.E.1    Child, J.A.2    Hawkins, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.