Pesticide exposure and inherited variants in vitamin d pathway genes in relation to prostate cancer

Cancer Epidemiology Biomarkers and Prevention

Volumn 22, Issue 9, 2013, Pages 1557-1566

  Karami, Sara ^a   Andreotti, Gabriella ^a   Koutros, Stella ^a   Barry, Kathryn Hughes ^a   Moore, Lee E ^a   Han, Summer ^a   Hoppin, Jane A ^c   Sandler, Dale P ^c   Lubin, Jay H ^a   Burdette, Laurie A ^b   Yuenger, Jeffrey ^b   Yeager, Meredith ^b   Freeman, Laura E Beane ^a   Blair, Aaron ^a   Alavanja, Michael C R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4,5 TRICHLOROPHENOXYACETIC ACID; CHOLESTANETRIOL 26 MONOOXYGENASE; CYANAZINE; DICAMBA; PARAQUAT; PARATHION; PESTICIDE; RETINOID X RECEPTOR ALPHA; RETINOID X RECEPTOR BETA; TERBUFOS; VITAMIN D; VITAMIN D BINDING PROTEIN;

ADULT; AGED; ARTICLE; CANCER RISK; CARCINOGEN DNA INTERACTION; CASE CONTROL STUDY; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FAMILY HISTORY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; PROTECTIVE EQUIPMENT; QUESTIONNAIRE; SINGLE NUCLEOTIDE POLYMORPHISM; VITAMIN D RESPONSIVE ELEMENT;

AGED; AGED, 80 AND OVER; APOPTOSIS; CASE-CONTROL STUDIES; CELL GROWTH PROCESSES; COHORT STUDIES; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PESTICIDES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATIC NEOPLASMS; QUESTIONNAIRES; RISK FACTORS; UNITED STATES; VITAMIN D;

EID: 84884144914     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-12-1454     Document Type: Article

References (64)

1. Adorini L, Penna G, Amuchastegui S, Cossetti C, Aquilano F, Mariani R, et al. Inhibition of prostate growth and inflammation by the vitamin D receptor agonist BXL-628 (elocalcitol). J Steroid Biochem Mol Biol 2007;103: 689-93.
2. Holick MF, Chen TC. Vitamin D and prostate cancer prevention and treatment. Trends Endocrinol Metab 2003;14: 423-30.
3. Zhuang SH, Burnstein KL. Antiproliferative effect of 1alpha,25- dihydroxyvitamin D3 in human prostate cancer cell line LNCaP involves reduction of cyclin-dependent kinase 2 activity and persistent G1 accumulation. Endocrinology 1998;139: 1197-207.
4. Garland CF, Gorham ED, Mohr SB, Garland FC. Vitamin D for cancer prevention: global perspective. Ann Epidemiol 2009;19: 468-83.
5. Krause R, Matulla-Nolte B, Essers M, Brown A, Hopfenmüller W. UV radiation and cancer prevention: what is the evidence? Anticancer Res 2006;26: 2723-7.
6. Colli JL, Grant WB. Solar ultravioletBradiation compared with prostate cancer incidence and mortality rates in United States. Urology 2008;71: 531-5.
7. Gilbert R, Metcalfe C, Oliver SE, Whiteman DC, Bain C, Ness A, et al. Life course sun exposure and risk of prostate cancer: populationbased nested case-control study and meta-analysis. Int J Cancer 2009;125: 1414-23.
8. Loke TW, Seyfi D, Khadra M. Prostate cancer incidence in Australia correlates inversely with solar radiation. BJU Int 2011;108(Suppl 2): 66-70.
9. John EM, Schwartz GG, Koo J, Van Den Berg D, Ingles SA. Sun exposure, vitamin D receptor gene polymorphisms, and risk of advanced prostate cancer. Cancer Res 2005;65: 5470-9.
10. Blair A, Malker H, Cantor KP, Burmeister L, Wiklund K. Cancer among farmers. A review. Scand J Work Environ Health 1985;11: 397-407.
11. Blair A, Freeman LB. Epidemiologic studies in agricultural populations: observations and future directions. J Agromedicine 2009;14: 125-31.
12. Koutros S, Alavanja MC, Lubin JH, Sandler DP, Hoppin JA, Lynch CF, et al. An update of cancer incidence in the Agricultural Health Study. J Occup Environ Med 2010;52: 1098-105.
13. Bonner MR, Williams BA, Rusiecki JA, Blair A, Beane Freeman LE, Hoppin JA, et al. Occupational exposure to terbufos and the incidence of cancer in the Agricultural Health Study. Cancer Causes Control 2010;21: 871-7.
14. Van Maele-Fabry G, Willems JL. Prostate cancer among pesticide applicators: a meta-analysis. Int Arch Occup Environ Health 2004; 77: 559-70.
15. Landau-Ossondo M, Rabia N, Jos-Pelage J, Marquet LM, Isidore Y, Saint-Aim-e C, et al. Why pesticides could be a common cause of prostate and breast cancers in the French Caribbean Island, Martinique. An overview on key mechanisms of pesticide-induced cancer. Biomed Pharmacother 2009;63: 383-95.
16. Gray LE Jr, Kelce WR. Latent effects of pesticides and toxic substances on sexual differentiation of rodents. Toxicol Ind Health 1996; 12: 515-31.
17. Agrawal D, Sultana P, Gupta GS. Oxidative damage and changes in the glutathione redox system in erythrocytes from rats treated with hexachlorocyclohexane. Food Chem Toxicol 1991;29: 459-62.
18. Ralph JL, Orgebin-Crist MC, Lareyre JJ, Nelson CC. Disruption of androgen regulation in the prostate by the environmental contaminant hexachlorobenzene. Environ Health Perspect 2003;111: 461-6.
19. Matesic DF, Blommel ML, Sunman JA, Cutler SJ, Cutler HG. Prevention of organochlorine-induced inhibition of gap junctional communication by chaetoglobosin K in astrocytes. Cell Biol Toxicol 2001;17: 395-408.
20. Koutros S, Beane Freeman LE, Berndt SI, Andreotti G, Lubin JH, Sandler DP, et al. Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer. Cancer Res 2010: 70: 9224-33.
21. Coble J, ThomasKW, Hines CJ, Dosemeci M, Curwin B, Lubin JH, et al. An updated algorithm for estimation of pesticide exposure intensity in the Agricultural Health Study. Int J Environ Res Public Helath 2011;8: 4608-22.
22. Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA. Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 2004;74: 106-20.
23. Verboven C, Rabijns A, De Maeyer M, Van Baelen H, Bouillon R, De Ranter C. A structural basis for the unique binding features of the human vitamin D binding protein. Nat Struct Biol 2002;9: 131-6.
24. Takeyama K, Kato S. The vitamin D3 1alpha-hydroxylase gene and its regulation by active vitamin D3. Biosci Biotechnol Biochem 2011; 75: 208-13.
25. Inaba Y,Yamamoto K, Yoshimoto N, Matsunawa M, Uno S, Yamada S, et al. Vitamin D3 derivatives with adamantane or lactone ring side chains are cell type-selective vitamin D receptor modulators. Mol Pharmacol 2007;71: 1298-311.
26. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B 1995;57: 289-300.
27. U.S. Environmental Protection Agency Technology Transfer Network Air Toxics Web Site. Parathion. 2012 [updated 2007 Nov 6; accessed 2012 Aug 9]. Available from: http://www.epa.gov/ttn/atw/hlthef/parathio. html.
28. U.S. Environmental Protection Agency Office of Pesticide Programs. Reregistration eligibility decision for terbufos. 2012 [updated 2006 July 31; accessed 2012 Aug 9]. Available from: http://www.epa.gov/oppsrrd1/REDs/terbufos- red.pdf.
29. Office of Pesticide Programs U.S. Environmental Protection Agency. Chemicals Evaluated for Carcinogenic Potential. [updated 2010 Aug.; accessed 2013 July 29]. Available from: http://www.pesticide. org/get-the-facts/ncap- publications-and-reports/general-reportsand- publications/corrected-2010-cancer- report-public.pdf.
30. Alavanja MC, Samanic C, Dosemeci M, Lubin J, Tarone R, Lynch CF, et al. Use of agricultural pesticides and prostate cancer risk in the Agricultural Health Study cohort. Am J Epidemiol 2003;157: 800-14.
31. Cantor KP, Blair A, Everett G, Gibson R, Burmeister LF, Brown LM, et al. Pesticides and other agricultural risk factors for non-Hodgkin's lymphoma among men in Iowa and Minnesota. Cancer Res 1992;52: 2447-55.
32. De Roos AJ, Zahm SH, Cantor KP, Weisenburger DD, Holmes FF, Burmeister LF, et al. Integrative assessment of multiple pesticides as risk factors for non-Hodgkin's lymphoma among men. Occup Environ Med 2003;60:E11.
33. U.S. Department of Health and Human Services Public Health Service Agency for Toxic Substances and Disease Registry. Toxicological profile for methyl parathion. 2012 [updated 2001 Sept.; accessed 2012 Aug 9]. Available from: http://www.atsdr.cdc.gov/toxprofiles/tp48.pdf.
34. Koutros S, Beane Freeman LE, Lubin JH, Heltshe SL, Andreotti G, Barry KH, et al. Risk of total and aggressive prostate cancer and pesticide use in the Agricultural Health Study. Am J Epidemiol 2013; 177: 59-74.
35. Koutros S, Andreotti G, Berndt SI, Hughes Barry K, Lubin JH, Hoppin JA, et al. Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer. Pharmacogenet Genomics 2011;21: 615-23.
36. Dennis LK, Lynch CF, Sandler DP, Alavanja MC. Pesticide use and cutaneous melanoma in pesticide applicators in the agricultural heath study. Environ Health Perspect 2010;118: 812-7.
37. Calaf GM, Roy D. Gene expression signature of parathion-transformed human breast epithelial cells. Int J Mol Med 2007;19: 741-50.
38. National Toxicology Program. Bioassay of parathion for possible carcinogenicity. Bethesda (MD): U.S. Department of Health, Education, and Welfare; National Cancer Institute Carcinogenesis Technical Report Series; 1979. Report No.: 70. CAS No.: 56-38-2. p. 1-123.
39. Ahn J, Albanes D, Berndt SI, Peters U, Chatterjee N, Freedman ND, et al. Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk. Carcinogenesis 2009;30: 769-76.
40. Hibler EA, Hu C, Jurutka PW, Martinez ME, Jacobs ET. Polymorphic variation in the GC and CASR genes and associations with vitamin D metabolite concentration and metachronous colorectal neoplasia. Cancer Epidemiol Biomarkers Prev 2011;21: 368-75.
41. Suzuki M, Yoshioka M, Hashimoto M, Murakami M, Kawasaki K, Noya M, et al. 25-hydroxyvitamin D, vitaminDreceptor gene polymorphisms, and severity of Parkinson's disease. Mov Disord 2011;27: 264-71.
42. Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, Berry D, et al. Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet 2010;376: 180-8.
43. Ahn J, Yu K, Stolzenberg-Solomon R, Simon KC, McCullough ML, Gallicchio L, et al. Genome-wide association study of circulating vitamin D levels. Hum Mol Genet 2010;19: 2739-45.
44. Bonilla C, Hooker S, Mason T, Bock CH, Kittles RA. Prostate cancer susceptibility loci identified on chromosome 12 in African Americans. PLoS ONE 2011;6:e16044.
45. Abbas S, Nieters A, Linseisen J, Slanger T, Kropp S, Mutschelknauss EJ, et al. Vitamin D receptor gene polymorphisms and haplotypes and postmenopausal breast cancer risk. Breast Cancer Res 2008;10:R31.
46. National Cancer Institute Core Genotyping Facility. Variant GPS. 2012 [accessed 2012 Aug 9]. Available from: http://variantgps.nci.nih.gov/cgfseq/ pages/snp500.do.
47. Ventura S, Pennefather J, Mitchelson F. Cholinergic innervation and function in the prostate gland. Pharmacol Ther 2002;94: 93-112.
48. Turner KJ, Barlow NJ, Struve MF, Wallace DG, Gaido KW, Dorman DC, et al. Effects of in utero exposure to the organophosphate insecticide fenitrothion on androgen-dependent reproductive development in the Crl:CD(SD)BR rat. Toxicol Sci 2002;68: 174-83.
49. Tamura H, Yoshikawa H, Gaido KW, Ross SM, DeLisle RK, Welsh WJ, et al. Interaction of organophosphate pesticides and related compounds with the androgen receptor. Environ Health Perspect 2003; 111: 545-52.
50. Padungtod C, Lasley BL, Christiani DC, Ryan LM, Xu X. Reproductive hormone profile among pesticide factory workers. J Occup Environ Med 1998;40: 1038-47.
51. Peiris-John RJ, Wickremasinghe R. Impact of low-level exposure to organophosphates on human reproduction and survival. Trans R Soc Trop Med Hyg 2008;102: 239-45.
52. Huggins C, Hodges CV. Studies on prostatic cancer. I. The effect of castration, of estrogen, and of androgen injection on serum phosphatases inmetastatic carcinoma of the prostate.CancerRes1941;1: 293-7.
53. Huggins C, Stevens R, Hodges C. Studies on prostatic cancer. II. The effects of castration on advanced carcinoma of the prostate gland. Arch Surg 1941;43: 209-23.
54. Lee WJ, Colt JS, Heineman EF, McComb R, Weisenburger DD, Lijinsky W, et al. Agricultural pesticide use and risk of glioma in Nebraska, United States. Occup Environ Med 2005;62: 786-92.
55. Delancey JO, Alavanja MC, Coble J, Blair A, Hoppin JA, Austin HD, et al. Occupational exposure to metribuzin and the incidence of cancer in the Agricultural Health Study. Ann Epidemiol 2009;19: 388-95.
56. U.S. Environmental Protection Agency Pesticide Registration. Atrazine updates. 2013 [updated 2013 Jan 31; accessed 2012 Aug 9]. Available from: http://www.epa.gov/opp00001/reregistration/atrazine/atrazine- update.htm.
57. U.S. Environmental Protection Agency Integrated Risk Information System. Metribuzin. 2012 [updated 2012 Aug. 9; accessed 2012 Aug 9]. Available from: http://www.epa.gov/iris/subst/0075.htm.
58. Freeman LE, Rusiecki JA, Hoppin JA, Lubin JH, Koutros S, Andreotti G, et al. Atrazine and cancer incidence among pesticide applicators in the agricultural health study (1994-2007). Environ Health Perspect 2011; 119: 1253-9.
59. Andreotti G, Koutros S, Berndt SI, Barry KH, Hou L, Hoppin JA, et al. The interaction between pesticide use and genetic variants involved in lipid metabolism on prostate cancer risk. J Cancer Epidemiol 2012;2012: 358076.
60. Barry KH, Koutros S, Andreotti G, Sandler DP, Burdette LA, Yeager M, et al. Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk. Carcinogenesis 2012; 33: 331-7
61. Blair A, Tarone R, Sandler D, Lynch CF, Rowland A, Wintersteen W, et al. Reliability of reporting on life-style and agricultural factors by a sample of participants in the Agricultural Health Study from Iowa. Epidemiology 2002;13: 94-9.
62. Hoppin JA, Yucel F, Dosemeci M, Sandler DP. Accuracy of selfreported pesticide use duration information from licensed pesticide applicators in the Agricultural Health Study. J Expo Anal Environ Epidemiol 2002;12: 313-8.
63. Thomas KW, Dosemeci M, Coble JB, Hoppin JA, Sheldon LS, Chapa G, et al. Assessment of a pesticide exposure intensity algorithm in the agricultural health study. J Expo Sci Environ Epidemiol 2010;20: 559-69.
64. Blair A, Thomas KT, Coble J, Sandler DP, Hines CJ, Lynch CF, et al. Impact of pesticide exposuremisclassification on estimates of relative risks in the Agricultural Health Study. Occup Environ Med 2011;68: 537-41.