Gene expression signature of parathion-transformed human breast epithelial cells

International Journal of Molecular Medicine

Volumn 19, Issue 5, 2007, Pages 741-750

  Calaf, Gloria M ^a,b   Roy, Debasish ^c  

^a UNIVERSIDAD DE TARAPACÁ   (Chile)

^b New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Malignant transformation of breast epithelial cells; Organophosphorous pesticides; Parathion

Indexed keywords

ATROPINE; COMPLEMENTARY DNA; PARATHION;

ARTICLE; BREAST; CELL CYCLE; CELL LINE; CELL PROLIFERATION; CELL TRANSFORMATION; CYTOLOGY; DNA MICROARRAY; DRUG EFFECT; EPITHELIUM CELL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; PHENOTYPE;

ATROPINE; BREAST; CELL CYCLE; CELL LINE, TRANSFORMED; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DNA, COMPLEMENTARY; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARATHION; PHENOTYPE;

EID: 34248531130     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.19.5.741     Document Type: Article

References (51)

1. Krieger N: Exposure, susceptibility and breast cancer risk: a hypothesis regarding exogenous carcinogens, breast tissue development, and social gradients, including black/white differences, in breast cancer incidence. Breast Cancer Res Treat 13: 205-222, 1989.
2. Davis DL, Axelrod D, Bailey L, Gaynor M and Sasco AJ: Rethinking breast cancer risk and the environment: the case for the precautionary principle. Environ Health Perspect 106: 523-529, 1998.
3. Khayat D, Giroux B, Berille J, Cour V, Gerard B, Sarkany M, Bertrand P and Bizzari JP: Fotemustine in the treatment of brain primary tumors and metastases. Cancer Invest 12: 414-420, 1994.
4. Patel SV: Pharmacotherapy of cognitive impairment in Alzheimer's disease: a review. J Geriatr Psychiatry Neurol 8: 81-95, 1995.
5. Meinking TL, Entzel P, Villar ME, Vicaria M, Lemard GA and Porcelain SL: Comparative efficacy of treatments for pediculosis capitis infestations: update 2000. Arch Dematol 137: 287-292, 2001.
6. Klaasen C: Nonmetallic environmental toxicants: air pollutants, solvents and vapors, and pesticides. In: The Pharmacological Basis of Therapeutics. Goodman Gilman A, Rall TW, Nies AS and Taylor P (eds). Pergamon Press Inc, New York, pp1615-1635, 1990.
7. Taylor P: The cholinesterase. J Biol Chem 266: 4025-4028, 1991.
8. Cabello G, Valenzuela M, Vilaxa A, Durán V, Rudolph I, Hrepic N and Calaf G: A rat mammary tumor model induced by the organophosphorous pesticides, parathion and malathion, possibly through acetylcholinesterase inhibition. Environ Health Perspect 109: 471-479, 2001.
9. Loeb LA: Mutator phenotype may be required for multistage carcinogenesis. Cancer Res 51: 3075-3079, 1991.
10. Knudson AG: Hereditary cancer, oncogenes and antioncogenes. Cancer Res 45: 1437-1443, 1985.
11. Schwab M, Varmus HE and Bishop JM: Amplification of cellular oncogenes in tumor cells. In: Cancer Cells. Vande Woude GF (ed). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp215-220, 1984.
12. Roy D, Calaf G and Hei TK: Profiling of differentially expressed genes induced by high linear energy transfer radiation in breast epithelial cells. Mol Carcinog 31: 192-203, 2001.
13. Calaf G and Hei TK: Establishment of a radiation- and estrogen-induced breast cancer. Carcinogenesis 21: 769-776, 2000.
14. Calaf G, Alvarado M and Hei TK: Beta catenin is associated with breast cancer progression in vitro. Int J Oncol 26: 913-921, 2005.
15. Calaf G, Roy D and Hei TK: Immunochemical analysis of protein in breast epithelial cells transformed by estrogens and high linear energy transfer (LET) radiation. Histochem Cell Biol 124: 261-274, 2005.
16. Calaf G, Alvarado ME and Hei TK: Oncoprotein expression and morphological phenotypes of human breast epithelial cell transformed by c-Ha-ras oncogene. Oncol Rep 14: 885-893, 2005.
17. Hines SJ, Litz JS and Krystal GW: Coexpression of c-kit and stem cell factor in breast cancer results in enhanced sensitivity to members of the EGF family of growth factors. Breast Cancer Res Treat 58: 1-10, 1999.
18. Ko CD, Kim JS, Ko BG, Son BH, Kang HJ, Yoon HS, Cho EY, Gong G and Ahn SH: The meaning of the c-kit proto-oncogene product in malignant transformation in human mammary epithelium. Clin Exp Metastasis 20: 593-597, 2003.
19. Debant A, Serra-Pages C, Seipel K, O'Brien S, Tang M, Park SH and Streuli M: The multi-domain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate Rac-specific and Rho-specific guanine nucleotide exchange factor domains. Proc Natl Acad Sci USA: 93: 5466-5471, 1996.
20. Elson A and Leder P: Protein tyrosine phosphatase ε. An isoform specifically expressed in mouse mammary tumors initiated by v-Ha-Ras. J Biol Chem 270: 26116-26122, 1995.
21. Olofsson B, Chardin P, Touchot N, Zahraoui A and Tavitian A: Expression of the ras-related ral A, rho 12 and rab genes in adult mouse tissues. Oncogene 3: 231-234, 1985.
22. Yeramian P, Chardin P, Madaule P and Tavitian A: Nucleotide sequence of human rho cDNA clone 12. Nucleic Acids Res 15: 1869, 1987.
23. Garrett MD, Self AJ, Van Oers C and Hall A: Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins. J Biol Chem 264: 10-13, 1989.
24. Lui VW and Grandis JR: EGFR-mediated cell cycle regulation. Anticancer Res 22: 1-11, 2002.
25. Rubin I and Yarden Y: The basic biology of HER2. Ann Oncol 12: S3-S8, 2001.
26. Yamamoto T, Ikawa S, Akiyama T, Semba K, Nomura N, Miyajima N, Saito T and Toyoshima K: Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor. Nature 319: 230-234, 1986.
27. Kraus MH, Issing W, Miki T, Popescu NC and Aaronson SA: Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc Nat Acad Sci USA 86: 9193-9197, 1989.
28. Kopan R and Weintraub H: Mouse notch: expression in hair follicles correlates with cell fate determination. J Cell Biol 121: 631-641, 1993.
29. Miele L, Miao H and Nickoloff BJ: NOTCH signaling as a novel cancer therapeutic target. Curr Cancer Drug Targets 4: 313-323, 2006.
30. Wagner U, Brownlees J, Irving NG, Lucas FR, Salinas PC and Miller CC: Overexpression of the mouse dishevelled-1 protein inhibits GSK-3β mediated phosphorylation of tau transfected mammalian cells. FEBS Lett 411: 369-372, 1997.
31. Gould KL, Bretscher A, Esch FS and Hunter T: cDNA cloning and sequencing of the protein-tyrosine kinase substrate, Ezrin, reveals homology to band 4.1. EMBO J 8: 4133-4142, 1989.
32. Algrain M, Turunen O, Vaheri A, Louvard D and Arpin M: Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linker. J Cell Biol 120: 129-139, 1993.
33. Takayama T, Shiozaki H, Shibamoto S, Oka H, Kimura Y, Tamura S, Inoue M, Monden T, Ito F and Monden M: Beta-catenin expression in human cancers. Am J Pathol 148: 39-46, 1996.
34. Breen E, Steele G Jr and Mercurio AM: Role of the E-cadherin/ alpha-catenin complex in modulating cell-cell and cell-matrix adhesive properties of invasive colon carcinoma cells. Ann Surg Oncol 2: 378-385, 1995.
35. Levine AJ, Momand J and Finlay CA: The p53 tumor suppressor gene. Nature 351: 453-456, 1991.
36. Callahan R: p53 mutations, another breast cancer prognostic factor. J Natl Cancer Inst 84: 826-827, 1992.
37. Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, et al: Mutations in p53 gene occur in diverse human tumor types. Nature 342: 705-708, 1989.
38. Nurse P: A long twentieth century of the cell cycle and beyond. Cell 100: 71-80, 2000.
39. Deshaies RJ: The self-destructive personality of a cell cycle in transition. Curr Opin Cell Biol 7: 781-789, 1995.
40. Gardner RD and Burke DJ: The spindle checkpoint: two transitions, two pathways. Trends Cell Biol 10: 154-158, 2000.
41. Dasika GK, Lin SC, Zhao S, Sung P, Tomkinson A and Lee EY: DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis. Oncogene 18: 7883-7899, 1999.
42. Bottazzi ME and Assoian RK: The extracellular matrix and mitogenic growth factors control G1 phase cyclins and cyclin-dependent kinase inhibitors. Trends Cell Biol 7: 348-352, 1997.
43. Soule HD, Maloney TM, Wolman SR, Peterson WD Jr, Brenz R, McGrath CM, Russo J, Pauley RJ, Jones RF and Brooks SC: Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res 50: 6075-6086, 1990. (Pubitemid 20331424)
44. Calaf G and Hei TK: Oncoprotein expressions in human breast epithelial cells transformed by high-LET radiation. Int J Radiat Biol 77: 31-40, 2001. (Pubitemid 32096694)
45. Calaf G, Russo J and Alvarado ME: Morphological phenotypes in neoplastic progression of benz (alpha) pyrene-treated breast epithelial cells. J Submicrosc Cytol Pathol 32: 535-545, 2000.
46. Calaf G and Russo J: Transformation of human breast epithelial cells by chemical carcinogens. Carcinogenesis 14: 483-492, 1993.
47. Sambrook J, Fritsch EF and Maniatis T: Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989.
48. Roy D, Calaf G and Hei TK: Frequent allelic imbalance on chromosome 6 and 17 correlate with radiation-induced neoplastic transformation of human breast epithelial cells. Carcinogenesis 22: 1685-1692, 2001.
49. Kleer CG, Van Golen KL, Zhang Y, Wu ZF, Rubin MA and Merajver SD: Characterization of Rho C expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability. Am J Pathol 160: 579-584, 2002.
50. Zhou H, Calaf G and Hei TK: Malignant transformation of human bronchial epithelial cells with the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1- (3-pyridyl)-1-butatone. Int J Cancer 106: 821-826, 2003.
51. Appella E and Anderson CW: Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem 268: 2764-2772, 2001.