Behavior of printable formulations of loperamide and caffeine on different substrates - Effect of print density in inkjet printing

International Journal of Pharmaceutics

Volumn 453, Issue 2, 2013, Pages 488-497

  Genina, Natalja ^a   Fors, Daniela ^a   Palo, Mirja ^a   Peltonen, Jouko ^a   Sandler, Niklas ^a  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

Author keywords

Caffeine; Flexible doses; Inkjet printing; Loperamide hydrochloride; Personalized medicine

Indexed keywords

CAFFEINE; LOPERAMIDE;

ARTICLE; CONTACT ANGLE; CONTENT ANALYSIS; CRYSTALLIZATION; DENSITY; DRUG FORMULATION; PRINTING; PRIORITY JOURNAL; SOLUBILITY; SURFACE TENSION; THERMAL ANALYSIS; VISCOSITY;

EID: 84884128481     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.06.003     Document Type: Article

References (37)

1. Breitkreutz, J., Boos, J., 2007. Paediatric and geriatric drug delivery. Exp. Opin. Drug Deliv. 4, 37-45. (Pubitemid 46117485)
2. Buanz, A.B.M., Saunders, M.H., Basit, A.W., Gaisford, S., 2011. Preparation of personalized-dose salbutamol sulphate oral films with thermal ink-jet printing. Pharm. Res. 28, 2386-2392.
3. Caffeine, 2011. European Pharmacopoeia, seventh ed. Council of Europe, Strasbourg, pp. 1536-1537.
4. Calvert, P., 2001. Inkjet printing for materials and devices. Chem. Mater. 13, 3299-3305. (Pubitemid 32999277)
5. Cilurzo, F., Minghetti, P., Casiraghi, A., Tosi, L., Pagani, S., Montanari, L., 2005. Polymethacrylates as crystallization inhibitors in monolayer transdermal patches containing ibuprofen. Eur. J. Pharm. Biopharm. 60, 61-66. (Pubitemid 40545861)
6. Dimatix Materials Printer DMP2800 Series User Manual, 2010. FUJIFILM Dimatix, Inc, Santa Clara, California.
7. Dong, H., Carr, W.W., Morris, J.F., 2006. Visualization of drop-on-demand inkjet: drop formation and deposition. Rev. Sci. Intrum. 77, 085101-085108.
8. Dow Answer Center, 2011. https://dow-answer.custhelp.com/app/answers/ detail/a-id/7740/~/propylene-glycol-usp%2Fep-pharmaceutical-ingredient- solubility-data (accessed March 26th, 2013).
9. Genina, N., Fors, D., Vakili, H., Ihalainen, P., Pohjala, L., Ehlers, H., Kassamakov, I., Haeggström, E., Vuorela, P., Peltonen, J., Sandler, N., 2012. Tailoring controlled-release oral dosage forms by combining inkjet and flexographic printing techniques. Eur. J. Pharm. Sci. 47, 615-623.
10. Genina, N., Janßen, E.M., Breitenbach, A., Breitkreutz, J., Sandler, N., 2013. Evaluation of different substrates for inkjet-printing of rasagiline mesylate. Eur. J. Pharm. Biopharm., in press.
11. Hamburg, M.A., Collins, F.S., 2010. The path to personalized medicine. N. Engl. J. Med. 363, 301-304.
12. Hsu, H.-Y., Toth, S., Simpson, G.J., Taylor, L.S., Harris, M.T., 2013. Effect of substrates on naproxen-polyvinylpyrrolidone solid dispersions formed via the drop printing technique. J. Pharm. Sci. 102, 638-648.
13. Huang, Q., Shen, W., Song, W., 2012. Synthesis of colourless silver precursor ink for printing conductive patterns on silicon nitride substrates. Appl. Surf. Sci. 258, 7384-7388.
14. Jang, D., Kim, D., Moon, J., 2009. Influence of fluid physical properties on ink-jet printability. Langmuir 25, 2629-2635.
15. Janßen, E.M., Schliephacke, R., Breitenbach, A., Breitkreutz, J., 2013. Drug-printing by flexographic printing technology - a new manufacturing process for orodispersible films. Int. J. Pharm. 441, 818-825.
16. Jones, D., 2007. Steps on the road to personalized medicine. Nat. Rev. Drug Discov. 6, 770-771. (Pubitemid 47500502)
17. Jøgensen, A., Rantanen, J., Karjalainen, M., Khriachtchev, L., Räsänen, E., Yliruusi, J., 2002. Hydrate formation during wet granulation studied by spectroscopic methods and multivariate analysis. Pharm. Res. 19, 1285-1291.
18. Lee, B.K., Yun, Y.H., Choi, J.S., Choi, Y.C., Kim, J.D., Cho, Y.W., 2012. Fabrication of drug-loaded polymer microparticles with arbitrary geometries using a piezoelectric inkjet printing system. Int. J. Pharm. 427, 305-310.
19. Lehto, V.-P., Laine, E., 1998. A kinetic study of polymorphic transition of anhydrous caffeine with microcalorimeter. Thermochim. Acta 317, 47-58. (Pubitemid 128349572)
20. Link, N., Semiat, R., 2009. Ink drop motion in wide-format printers I. Drop flow from Drop-On-Demand (DOD) printing heads. Chem. Eng. Process. 48, 68-83.
21. th, 2013).
22. Loperamide Hydrochloride, 2011. European Pharmacopoeia, seventh ed. Council of Europe, Strasbourg, pp. 2376-2377.
23. Melèndez, P.A., Kane, K.M., Ashvar, C.S., Albrecht, M., Smith, P.A., 2008. Thermal inkjet application in the preparation of oral dosage forms: dispensing of prednisolone solutions and polymorphic characterization by solid-state spectroscopic techniques. J. Pharm. Sci. 97, 2619-2636.
24. Notz, P.K., Chen, A.U., Basaran, O.A., 2001. Satellite drops: unexpected dynamics and change of scaling during pinch-off. Phys. Fluids 13, 549-552.
25. Pardeike, J., Strohmeier, D.M., Schrodl, N., Voura, C., Gruber, M., Khinast, J.G., Zimmer, A., 2011. Nanosuspensions as advanced printing ink for accurate dosing of poorly soluble drugs in personalized medicines. Int. J. Pharm. 420, 93-100.
26. Quinn, M.E., 2009. Alcohol. In: Rowe, R.C., Sheskey, P.J., Quinn, M.E. (Eds.), Handbook of Pharmaceutical Excipients., sixth ed. Pharmaceutical Press and American Pharmacists Association, London, Chicago, pp. 17-19.
27. Rompay, J.V., Carter, J.E., 1990. Loperamide hydrochloride. In: Florey, K. (Ed.), Analytical Profiles of Drug Substances, vol. 19. Academic Press, INC., San Diego, California, pp. 341-365.
28. Scoutaris, N., Alexander, M.R., Gellert, P.R., Roberts, C.J., 2011. Inkjet printing as a novel medicine formulation technique. J. Control. Release 156, 179-185.
29. Sumerel, J., Lewis, J., Doraiswamy, A., Deravi, L.F., Sewell, S.L., Gerdon, A.E., Wright, D.W., Narayan, R.J., 2006. Piezoelectric ink jet processing of materials for medical and biological applications. Biotechnol. J. 1, 976-987.
30. Sun, J., Wei, X., Huang, B., 2012. Influence of the viscosity of edible ink to piezoelectric ink-jet printing drop state. Appl. Mech. Mater. 200, 676-680.
31. Takala, M., Helkio, H., Sundholm, J., Genina, N., Kiviluoma, P., Widmaier, T., Sandler, N., Kuosmanen, P., http://innomet.ttu.ee/daaam/ proceedings/pdf/Takala.pdf (accessed March 26th, 2013) 2012. Ink-jet printing of pharmaceuticals. In: 8th International DAAM Baltic Conference 'Industrial Engineering', Tallinn, Estonia, April 19-21.
32. Weller, P.J., 2009. Propylene glycol. In: Rowe, R.C., Sheskey, P.J., Quinn, M.E. (Eds.), Handbook of Pharmaceutical Excipients., sixth ed. Pharmaceutical Press and American Pharmacists Association, London, Chicago, pp. 592-594.
33. Wening, K., Breitkreutz, J., 2011. Oral drug delivery in personalized medicine: Unmet needs and novel approaches. Int. J. Pharm. 404, 1-9.
34. Weuts, I., Kempen, D., Decorte, A., Verreck, G., Peeters, J., Brewster, M., Mooter, G.V.d., 2004. Phase behaviour analysis of solid dispersions of loperamide and two structurally related compounds with the polymers PVP-K30 and PVP-VA64. Eur. J. Pharm. Sci. 22, 375-385. (Pubitemid 38953896)
35. Wikström, H., Rantanen, J., Gift, A.D., Taylor, L.S., 2008. Toward an understanding of the factors influencing anhydrate-to-hydrate transformation kinetics in aqueous environments. Cryst. Growth Des. 8, 2684-2693.
36. Wyttenbach, N., Alsenz, J., Grassmann, O., 2007. Miniaturized assay for solubility and residual solid screening (SORESOS) in early drug development. Pharm. Res. 24, 888-898. (Pubitemid 46675389)
37. Xu, Q., Basaran, O.A., 2007. Computational analysis of drop-on-demand drop formation. Phys. Fluids 19, 102111-102122.