Degradable and biocompatible nanoparticles decorated with cyclic RGD peptide for efficient drug delivery to hepatoma cells in vitro

International Journal of Pharmaceutics

Volumn 454, Issue 2, 2013, Pages 727-737

  Loyer, Pascal ^a   Bedhouche, Wahib ^a   Huang, Zhi Wei ^b,c   Cammas Marion, Sandrine ^b  

^a RENNES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c UNIVERSITÉ DE ROUEN   (France)

Author keywords

Anti cancer drug encapsulation; Biotinylated nanoparticles; Cyclic RGD peptide; Degradable poly(benzyl malate) derivatives; HepaRG hepatoma cells; Site specific targeting

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; BIOTIN; COPOLYMER; CYCLOPEPTIDE; DOXORUBICIN; FLUORESCENT DYE; MACROGOL; NANOCARRIER; STREPTAVIDIN;

ARTICLE; BIOCOMPATIBILITY; BIOTINYLATION; CANCER CELL CULTURE; CELL STRAIN HT29; CONTROLLED STUDY; CULTURE MEDIUM; DRUG DELIVERY SYSTEM; DRUG RELEASE; FEMALE; GENE OVEREXPRESSION; HELA CELL; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; KUPFFER CELL; LIVER CELL CARCINOMA; NANOENCAPSULATION; NANOMEDICINE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RETICULOENDOTHELIAL SYSTEM;

ANTI-CANCER DRUG ENCAPSULATION; BIOTINYLATED NANOPARTICLES; CYCLIC RGD PEPTIDE; DEGRADABLE POLY(BENZYL MALATE) DERIVATIVES; HEPARG HEPATOMA CELLS; SITE-SPECIFIC TARGETING;

ANTIBIOTICS, ANTINEOPLASTIC; BIOTIN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; HUMANS; LIVER NEOPLASMS; NANOPARTICLES; PEPTIDES, CYCLIC; POLYESTERS; POLYETHYLENE GLYCOLS;

EID: 84884126966     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.05.060     Document Type: Article

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