메뉴 건너뛰기




Volumn 92, Issue 10, 2013, Pages 1345-1350

Improved tolerability by a modified intermittent treatment schedule of dasatinib for patients with chronic myeloid leukemia resistant or intolerant to imatinib

Author keywords

CML; Dasatinib; Dosing; Resistance; Tolerability; Toxicity

Indexed keywords

ALPHA INTERFERON; CYTARABINE; DASATINIB; HYDROXYUREA; IMATINIB;

EID: 84883891271     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-013-1769-2     Document Type: Article
Times cited : (45)

References (28)
  • 1
    • 84883874144 scopus 로고    scopus 로고
    • Sprycel (dasatinib) package insert (2010). Princeton, New Jersey, Bristo-Myers Squibb Company
    • Sprycel (dasatinib) package insert (2010). Princeton, New Jersey, Bristo-Myers Squibb Company
  • 2
    • 84863011486 scopus 로고    scopus 로고
    • Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION)
    • 22160483 10.1182/blood-2011-08-376087 1:CAS:528:DC%2BC38XisFOitrg%3D
    • Kantarjian HM, Shah NP, Cortes JE et al (2012) Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION). Blood 119(5):1123-1129
    • (2012) Blood , vol.119 , Issue.5 , pp. 1123-1129
    • Kantarjian, H.M.1    Shah, N.P.2    Cortes, J.E.3
  • 3
    • 33745102555 scopus 로고    scopus 로고
    • Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
    • 16775234 10.1056/NEJMoa055229 1:CAS:528:DC%2BD28Xlslyisb0%3D
    • Talpaz M, Shah NP, Kantarjian H et al (2006) Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 354(24):2531-2541
    • (2006) N Engl J Med , vol.354 , Issue.24 , pp. 2531-2541
    • Talpaz, M.1    Shah, N.P.2    Kantarjian, H.3
  • 4
    • 19744365702 scopus 로고    scopus 로고
    • A small molecule-kinase interaction map for clinical kinase inhibitors
    • 15711537 10.1038/nbt1068 1:CAS:528:DC%2BD2MXitF2nt7w%3D
    • Fabian MA, Biggs WH 3rd, Treiber DK et al (2005) A small molecule-kinase interaction map for clinical kinase inhibitors. Nat Biotechnol 23(3):329-336
    • (2005) Nat Biotechnol , vol.23 , Issue.3 , pp. 329-336
    • Fabian, M.A.1    Biggs III, W.H.2    Treiber, D.K.3
  • 5
    • 21144451094 scopus 로고    scopus 로고
    • In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants
    • 15930265 10.1158/0008-5472.CAN-05-0259
    • O'Hare T, Walters DK, Stoffregen EP et al (2005) In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. Cancer Res 65(11):4500-4505
    • (2005) Cancer Res , vol.65 , Issue.11 , pp. 4500-4505
    • O'Hare, T.1    Walters, D.K.2    Stoffregen, E.P.3
  • 6
    • 70449704111 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of tyrosine kinase inhibitors
    • 19733976 10.1016/j.ctrv.2009.08.004
    • van Erp NP, Gelderblom H, Guchelaar HJ (2009) Clinical pharmacokinetics of tyrosine kinase inhibitors. Cancer Treat Rev 35(8):692-706
    • (2009) Cancer Treat Rev , vol.35 , Issue.8 , pp. 692-706
    • Van Erp, N.P.1    Gelderblom, H.2    Guchelaar, H.J.3
  • 7
    • 0033987746 scopus 로고    scopus 로고
    • Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
    • 10619854 10.1172/JCI9083 1:CAS:528:DC%2BD3cXislSktw%3D%3D
    • Druker BJ, Lydon NB (2000) Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia. J Clin Invest 105(1):3-7
    • (2000) J Clin Invest , vol.105 , Issue.1 , pp. 3-7
    • Druker, B.J.1    Lydon, N.B.2
  • 8
    • 49249121723 scopus 로고    scopus 로고
    • Intermittent target inhibition with dasatinib 100 mg once daily preserves efficacy and improves tolerability in imatinib-resistant and -intolerant chronic-phase chronic myeloid leukemia
    • 18541900 10.1200/JCO.2007.14.9260 1:CAS:528:DC%2BD1cXptlKgtb0%3D
    • Shah NP, Kantarjian HM, Kim DW et al (2008) Intermittent target inhibition with dasatinib 100 mg once daily preserves efficacy and improves tolerability in imatinib-resistant and -intolerant chronic-phase chronic myeloid leukemia. J Clin Oncol 26(19):3204-3212
    • (2008) J Clin Oncol , vol.26 , Issue.19 , pp. 3204-3212
    • Shah, N.P.1    Kantarjian, H.M.2    Kim, D.W.3
  • 9
    • 67650607999 scopus 로고    scopus 로고
    • Phase 3 study of dasatinib 140 mg once daily versus 70 mg twice daily in patients with chronic myeloid leukemia in accelerated phase resistant or intolerant to imatinib: 15-month median follow-up
    • 19369231 10.1182/blood-2008-11-186817 1:CAS:528:DC%2BD1MXnvFGnsrY%3D
    • Kantarjian H, Cortes J, Kim DW et al (2009) Phase 3 study of dasatinib 140 mg once daily versus 70 mg twice daily in patients with chronic myeloid leukemia in accelerated phase resistant or intolerant to imatinib: 15-month median follow-up. Blood 113(25):6322-6329
    • (2009) Blood , vol.113 , Issue.25 , pp. 6322-6329
    • Kantarjian, H.1    Cortes, J.2    Kim, D.W.3
  • 10
    • 79751533746 scopus 로고    scopus 로고
    • Management of adverse events associated with tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia
    • 20861918 10.1038/leu.2010.215 1:CAS:528:DC%2BC3MXhs1ams7c%3D
    • Jabbour E, Deininger M, Hochhaus A (2011) Management of adverse events associated with tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia. Leukemia 25(2):201-210
    • (2011) Leukemia , vol.25 , Issue.2 , pp. 201-210
    • Jabbour, E.1    Deininger, M.2    Hochhaus, A.3
  • 11
    • 70349306853 scopus 로고    scopus 로고
    • Dasatinib-associated major molecular responses in patients with chronic myeloid leukemia in chronic phase following imatinib failure: Response dynamics and predictive value
    • 19641527 10.1038/leu.2009.156 1:CAS:528:DC%2BD1MXhtV2rtrjF
    • Hochhaus A, Muller MC, Radich J et al (2009) Dasatinib-associated major molecular responses in patients with chronic myeloid leukemia in chronic phase following imatinib failure: response dynamics and predictive value. Leukemia 23(9):1628-1633
    • (2009) Leukemia , vol.23 , Issue.9 , pp. 1628-1633
    • Hochhaus, A.1    Muller, M.C.2    Radich, J.3
  • 12
    • 77953725855 scopus 로고    scopus 로고
    • Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
    • 20525995 10.1056/NEJMoa1002315 1:CAS:528:DC%2BC3cXnvVaktbY%3D
    • Kantarjian H, Shah NP, Hochhaus A et al (2010) Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 362(24):2260-2270
    • (2010) N Engl J Med , vol.362 , Issue.24 , pp. 2260-2270
    • Kantarjian, H.1    Shah, N.P.2    Hochhaus, A.3
  • 13
    • 56849117387 scopus 로고    scopus 로고
    • Transient potent BCR-ABL inhibition is sufficient to commit chronic myeloid leukemia cells irreversibly to apoptosis
    • 19061839 10.1016/j.ccr.2008.11.001 1:CAS:528:DC%2BD1cXhsFahsrfF
    • Shah NP, Kasap C, Weier C et al (2008) Transient potent BCR-ABL inhibition is sufficient to commit chronic myeloid leukemia cells irreversibly to apoptosis. Cancer Cell 14(6):485-493
    • (2008) Cancer Cell , vol.14 , Issue.6 , pp. 485-493
    • Shah, N.P.1    Kasap, C.2    Weier, C.3
  • 14
    • 73349122639 scopus 로고    scopus 로고
    • Chronic myeloid leukemia: An update of concepts and management recommendations of European LeukemiaNet
    • 19884523 10.1200/JCO.2009.25.0779 1:CAS:528:DC%2BC3cXhtVWisLY%3D
    • Baccarani M, Cortes J, Pane F et al (2009) Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet. J Clin Oncol 27(35):6041-6051
    • (2009) J Clin Oncol , vol.27 , Issue.35 , pp. 6041-6051
    • Baccarani, M.1    Cortes, J.2    Pane, F.3
  • 15
    • 54049139246 scopus 로고    scopus 로고
    • Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials
    • 18684859 10.1182/blood-2008-04-150680 1:CAS:528:DC%2BD1cXht1Omur3M
    • Branford S, Fletcher L, Cross NC et al (2008) Desirable performance characteristics for BCR-ABL measurement on an international reporting scale to allow consistent interpretation of individual patient response and comparison of response rates between clinical trials. Blood 112(8):3330-3338
    • (2008) Blood , vol.112 , Issue.8 , pp. 3330-3338
    • Branford, S.1    Fletcher, L.2    Cross, N.C.3
  • 16
    • 84867405606 scopus 로고    scopus 로고
    • Standardized definitions of molecular response in chronic myeloid leukemia
    • 22504141 10.1038/leu.2012.104 1:CAS:528:DC%2BC38XhsFSgu7zL
    • Cross NC, White H, Muller MC, Saglio G, Hochhaus A (2012) Standardized definitions of molecular response in chronic myeloid leukemia. Leukemia 26(10):2172-2175
    • (2012) Leukemia , vol.26 , Issue.10 , pp. 2172-2175
    • Cross, N.C.1    White, H.2    Muller, M.C.3    Saglio, G.4    Hochhaus, A.5
  • 17
    • 0344614012 scopus 로고    scopus 로고
    • Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR
    • 10557058 10.1038/sj.leu.2401566 1:CAS:528:DyaK1MXnvVKgurg%3D
    • Emig M, Saussele S, Wittor H et al (1999) Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR. Leukemia 13(11):1825-1832
    • (1999) Leukemia , vol.13 , Issue.11 , pp. 1825-1832
    • Emig, M.1    Saussele, S.2    Wittor, H.3
  • 18
    • 0027207407 scopus 로고
    • Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: Correlations with acute graft-versus-host disease and relapse
    • 8338780 10.1111/j.1365-2141.1993.tb03026.x 1:STN:280:DyaK3szjt1ylsg%3D%3D
    • Cross NC, Hughes TP, Feng L et al (1993) Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: correlations with acute graft-versus-host disease and relapse. Br J Haematol 84(1):67-74
    • (1993) Br J Haematol , vol.84 , Issue.1 , pp. 67-74
    • Cross, N.C.1    Hughes, T.P.2    Feng, L.3
  • 19
    • 3042612211 scopus 로고    scopus 로고
    • Denaturing-HPLC-based assay for detection of ABL mutations in chronic myeloid leukemia patients resistant to imatinib
    • 15107311 10.1373/clinchem.2004.031112 1:CAS:528:DC%2BD2cXlsFWgur0%3D
    • Soverini S, Martinelli G, Amabile M et al (2004) Denaturing-HPLC-based assay for detection of ABL mutations in chronic myeloid leukemia patients resistant to imatinib. Clin Chem 50(7):1205-1213
    • (2004) Clin Chem , vol.50 , Issue.7 , pp. 1205-1213
    • Soverini, S.1    Martinelli, G.2    Amabile, M.3
  • 20
    • 40849105148 scopus 로고    scopus 로고
    • Dynamics of BCR-ABL mutated clones prior to hematologic or cytogenetic resistance to imatinib
    • 18223278 10.3324/haematol.11993 1:CAS:528:DC%2BD1cXhsVSiu7zM
    • Ernst T, Erben P, Muller MC et al (2008) Dynamics of BCR-ABL mutated clones prior to hematologic or cytogenetic resistance to imatinib. Haematologica 93(2):186-192
    • (2008) Haematologica , vol.93 , Issue.2 , pp. 186-192
    • Ernst, T.1    Erben, P.2    Muller, M.C.3
  • 21
    • 70350727160 scopus 로고    scopus 로고
    • Acute dasatinib exposure commits Bcr-Abl-dependent cells to apoptosis
    • 19706883 10.1182/blood-2007-10-113969 1:CAS:528:DC%2BD1MXhtlensb7F
    • Snead JL, O'Hare T, Adrian LT et al (2009) Acute dasatinib exposure commits Bcr-Abl-dependent cells to apoptosis. Blood 114(16):3459-3463
    • (2009) Blood , vol.114 , Issue.16 , pp. 3459-3463
    • Snead, J.L.1    O'Hare, T.2    Adrian, L.T.3
  • 22
    • 0033585504 scopus 로고    scopus 로고
    • In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor
    • 9923858 10.1093/jnci/91.2.163
    • le Coutre P, Mologni L, Cleris L et al (1999) In vivo eradication of human BCR/ABL-positive leukemia cells with an ABL kinase inhibitor. J Natl Cancer Inst 91(2):163-168
    • (1999) J Natl Cancer Inst , vol.91 , Issue.2 , pp. 163-168
    • Le Coutre, P.1    Mologni, L.2    Cleris, L.3
  • 23
    • 3142676436 scopus 로고    scopus 로고
    • Overriding imatinib resistance with a novel ABL kinase inhibitor
    • 15256671 10.1126/science.1099480 1:CAS:528:DC%2BD2cXls1egtrY%3D
    • Shah NP, Tran C, Lee FY, Chen P, Norris D, Sawyers CL (2004) Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 305(5682):399-401
    • (2004) Science , vol.305 , Issue.5682 , pp. 399-401
    • Shah, N.P.1    Tran, C.2    Lee, F.Y.3    Chen, P.4    Norris, D.5    Sawyers, C.L.6
  • 24
    • 24344482346 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of imatinib
    • 16122278 10.2165/00003088-200544090-00001 1:CAS:528:DC%2BD2MXhtFSktbzF
    • Peng B, Lloyd P, Schran H (2005) Clinical pharmacokinetics of imatinib. Clin Pharmacokinet 44(9):879-894
    • (2005) Clin Pharmacokinet , vol.44 , Issue.9 , pp. 879-894
    • Peng, B.1    Lloyd, P.2    Schran, H.3
  • 25
    • 38949134552 scopus 로고    scopus 로고
    • Sprycel for chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia resistant to or intolerant of imatinib mesylate
    • 18223208 10.1158/1078-0432.CCR-07-4175 1:CAS:528:DC%2BD1cXhtVKisb0%3D
    • Brave M, Goodman V, Kaminskas E et al (2008) Sprycel for chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia resistant to or intolerant of imatinib mesylate. Clin Cancer Res 14(2):352-359
    • (2008) Clin Cancer Res , vol.14 , Issue.2 , pp. 352-359
    • Brave, M.1    Goodman, V.2    Kaminskas, E.3
  • 26
    • 62549108246 scopus 로고    scopus 로고
    • Clinical trials underestimate the age of chronic myeloid leukemia (CML) patients. Incidence and median age of Ph/BCR-ABL-positive CML and other chronic myeloproliferative disorders in a representative area in Germany
    • 18784744 10.1038/leu.2008.245 1:STN:280:DC%2BD1M7pvVSqsQ%3D%3D
    • Rohrbacher M, Berger U, Hochhaus A et al (2009) Clinical trials underestimate the age of chronic myeloid leukemia (CML) patients. Incidence and median age of Ph/BCR-ABL-positive CML and other chronic myeloproliferative disorders in a representative area in Germany. Leukemia 23(3):602-604
    • (2009) Leukemia , vol.23 , Issue.3 , pp. 602-604
    • Rohrbacher, M.1    Berger, U.2    Hochhaus, A.3
  • 27
    • 33947280081 scopus 로고    scopus 로고
    • Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy
    • 17138817 10.1182/blood-2006-09-047266 1:CAS:528:DC%2BD2sXnslygsrw%3D
    • Hochhaus A, Kantarjian HM, Baccarani M et al (2007) Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy. Blood 109(6):2303-2309
    • (2007) Blood , vol.109 , Issue.6 , pp. 2303-2309
    • Hochhaus, A.1    Kantarjian, H.M.2    Baccarani, M.3
  • 28
    • 79953823237 scopus 로고    scopus 로고
    • Poor adherence is the main reason for loss of CCyR and imatinib failure for chronic myeloid leukemia patients on long-term therapy
    • 21346253 10.1182/blood-2010-10-309807 1:CAS:528:DC%2BC3MXltFCrsb4%3D
    • Ibrahim AR, Eliasson L, Apperley JF et al (2011) Poor adherence is the main reason for loss of CCyR and imatinib failure for chronic myeloid leukemia patients on long-term therapy. Blood 117(14):3733-3736
    • (2011) Blood , vol.117 , Issue.14 , pp. 3733-3736
    • Ibrahim, A.R.1    Eliasson, L.2    Apperley, J.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.