Functional diversity of genes for the biosynthesis of paeoniflorin and its derivatives in Paeonia

International Journal of Molecular Sciences

Volumn 14, Issue 9, 2013, Pages 18502-18519

  Yuan, Yuan ^a   Yu, Jun ^b   Jiang, Chao ^a   Li, Minhui ^a   Lin, Shufang ^a   Wang, Xumin ^b   Huang, Luqi ^a  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Bark; Gallic acid; Gene expression; Orthologs; Paeonia; Paeoniflorin

Indexed keywords

3 DEHYDROQUINATE DEHYDRATASE; BENZOIC ACID; BENZOYLPAEONIFLORIN; GALLIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; PAEONIFLORIN; PEONOL; PEONY LACTONE GLYCOSIDE; PHOSPHOMEVALONATE KINASE; SHIKIMIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BARK; CARPEL; CORIARIA NEPALENSIS; CORRELATION ANALYSIS; FLOWER; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; MEDICINAL PLANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PAEONIA LACTIFLORA; PAEONIA SUFFRUTICOSA; PHYLOGENY; PLACAT GENE; PLANT GENE; PLANT ROOT; PLARODE1 GENE; PLARODE2 GENE; PLCMK GENE; PLDHQS GENE; PLDHS1 GENE; PLDHS2 GENE; PLDXPS1 GENE; PLDXPS2 GENE; PLDXPS3 GENE; PLDXR1 GENE; PLDXR2 GENE; PLHDR GENE; PLHDS GENE; PLHMGCR GENE; PLHMGS1 GENE; PLHMGS2 GENE; PLIDI GENE; PLISPD GENE; PLISPF GENE; PLMVD1 GENE; PLMVD2 GENE; PLMVK GENE; PLPMK GENE; POISON IVY; POMEGRANATE; RHUS RADICANS; SYNTHESIS;

BENZOATES; BRIDGED COMPOUNDS; GLUCOSIDES; PAEONIA; PHYLOGENY; PLANT PROTEINS;

EID: 84883889678     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms140918502     Document Type: Article

References (35)

1. He, D.; Dai, S. Anti-inflammatory and immunomodulatory effects of Paeonia lactiflora Pall., a traditional Chinese herbal medicine. Front Pharmacol. 2011, 2, doi:10.3389/fphar.2011.00010.
2. Peng, H.S.; Wang, D.Q. The development and evolution of differentiation between Radix Paeoniae Rubra and Radix Paeoniae Alba. Chin. J. Med. Hist. 2007, 37, 133-136.
3. Lin, H.C.; Ding, H.Y.; Wu, Y.C. Two novel compounds from Paeonia suffruticosa. J. Nat. Prod. 1998, 61, 343-346.
4. Zhang, X.; Wang, J.; Li, X. A study on the chemical constituents of Paeonia lactiflora Pall. J. Shenyang Pharm. Univ. 2001, 18, 30-32.
5. Tan, J.; Zhao, Q.; Yang, L.; Shang, Z.; Du, Z.; Yan, M. Chemical constituents in roots of Paeonia lactiflora. Chin. Tradit. Herb. Drugs 2010, 41, 1245-1248.
6. Wang, R.; Lu, T.; Li, Y.W.; Hu, Y.J.; Wang, Z.T. A comparison on pharmacological actions between Radix Paeoniae Rubra and Radix Paeoniae Alba. China J. Exper. Trad. Med. Form. 2010, 16, 113-114.
7. Li, H.; Wang, S.; Zhang, B. Pharmacological action and pharmacokinetics of paeonol. Asia-Pacific Tradit. Med. 2010, 6, 110-112.
8. Lau, C.H.; Chan, C.M.; Chan, Y.W. Pharmacological investigations of the anti-diabetic effect of Cortex Moutan and its active component paeonol. Phytomedicine 2007, 14, 778-784.
9. Sun, G.P.; Wan, X.; Xu, S.P.; Wang, H.; Liu, S.H.; Wang, Z.G. Antiproliferation and apoptosis induction of paeonol in human esophageal cancer cell lines. Dis. Esophaqus 2008, 21, 723-729.
10. Huang, X.; Zhu, W. The involvement of mitochondrial phosphate transporter in accelerating bud dormancy release during chilling treatment of tree peony (Paeonia suffruticosa). Planta 2008, 228, 545-552.
11. Zhao, D.; Tao, J.; Han, C.; Ge, J. Flower color diversity revealed by differential expression of flavonoid biosynthetic genes and flavonoid accumulation in herbaceous peony (Paeonia lactiflora Pall.). Mol. Biol. Rep. 2012, 39, 11263-11275.
12. Zhang, X.Y.; Li, X. Chemical research progress on white peony. Shenyang Pharm. Univ. Bulletin. 2002, 19, 70-73.
13. Kitagawa, I.; Yoshikawa, M.; Tsunaga, K. Moutanpi ingredients. Shyakugaku Zasshi. 1979, 33, 171-177.
14. Ren, Y.; Qu, W.; Liang, J. Progress on chemical constituents and anti-prostate cancer of Punica Granatum. Strait Pharm. J. 2011, 23, 7-11.
15. Djakpo, O.; Yao, W. Rhus Chinensis and Galla Chinensis-Folklore to modern evidence: Review. Phytother. Res. 2010, 24, 1739-1747.
16. Wei, H.; Zeng, F.J.; Lu, M.Y.; Tang, R.J. Studies on chemical constituents from the root of Coriaria nepalensis wall. Acta Pharm. Sin. 1998, 33, 688-692.
17. Rozen, S.; Skaletsky, H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol. 2000, 132, 365-386.
18. Thompson, J.D.; Higgins, D.G.; Gibson, T.J. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994, 22, 4673-4680.
19. Hittinger, C.T.; Carroll, S.B. Gene duplication and the adaptive evolution of a classic genetic switch. Nature 2007, 449, 677-681.
20. Ding, L.; Hofius, D.; Hajirezaei, M.R.; Fernie, A.R.; Bornke, F.; Sonnewald, U. Functional analysis of the essential bifunctional tobacco enzyme 3-dehydroquinate dehydratase/shikimate dehydrogenase in transgenic tobacco plants. J. Exp. Bot. 2007, 8, 2053-2067.
21. Lange, B.M.; Ketchum, R.E.; Croteau, R.B. Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis. Plant Physiol. 2001, 127, 305-314.
22. Ishiguro, S.; Nishimori, Y.; Yamada, M.; Saito, H.; Suzuki, T.; Nakagawa, T.; Miyake, H.; Okada, K.; Nakamura, K. The Arabidopsis FLAKY POLLEN1 gene encodes a 3-hydroxy-3-methylglutaryl-coenzyme A synthase required for development of tapetum-specific organelles and fertility of pollen grains. Plant Cell Physiol. 2010, 51, 896-911.
23. Yang, J.; Xian, M.; Su, S.; Zhao, G.; Nie, Q.; Jiang, X.; Zheng, Y.; Liu, W. Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. PLoS One 2012, 7, e33509.
24. Herdendorf, T.J.; Miziorko, H.M. Phosphomevalonate kinase: Functional investigation of the recombinant human enzyme. Biochemistry 2006, 45, 3235-3242.
25. Van Deenen, N.; Bachmann, A.L.; Schmidt, T.; Schaller, H.; Sand, J.; Prufer, D.; Schulze, G.C. Molecular cloning of mevalonate pathway genes from Taraxacum brevicorniculatum and functional characterisation of the key enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Mol. Biol. Rep. 2012, 39, 4337-4349.
26. Wang, H.; Nagegowda, D.A.; Rawat, R.; Bouvier-Nave, P.; Guo, D.; Bach, T.J.; Chye, M.L. Overexpression of Brassica juncea wild-type and mutant HMG-CoA synthase 1 in Arabidopsis up-regulates genes in sterol biosynthesis and enhances sterol production and stress tolerance. Plant Biotechnol. J. 2012, 10, 31-42.
27. Ohno, S. Evolution by Gene Duplication. Springer-Verlag: New York, NY, USA, 1970; pp. 59-87.
28. Rastogi, S.; Liberles, D. Subfunctionalization of duplicated genes as a transition state to neofunctionalization. BMC Evol. Biol. 2005, 5, 28.
29. Kanehisa, M.; Goto, S. KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 2000, 28, 27-30.
30. Altschul, S.F.; Madden, T.L.; Schaffer, A.A.; Zhang, J.; Zhang, Z.; Miller, W.; Lipman, D.J. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 1997, 25, 3389-3402.
31. Burge, C.B.; Karlin, S. Finding the genes in genomic DNA. Curr. Opin. Struct. Biol. 1998, 8, 346-354.
32. Bjellqvist, B.; Basse, B.; Olsen, E.; Celis, J.E. Reference points for comparisons of two-dimensional maps of proteins from different human cell types defined in a pH scale where isoelectric points correlate with polypeptide compositions. Electrophoresis 1994, 15, 529-539.
33. Quevillon, E.; Silventoinen, V.; Pillai, S.; Harte, N.; Mulder, N.; Apweiler, R.; Lopez, R. InterProScan: Protein domains identifier. Nucleic Acids Res. 2005, 33, W116-W120.
34. Tamura, K.; Peterson, D.; Peterson, N.; Stecher, G.; Nei, M.; Kumar, S. MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 2011, 28, 2731-2739.
35. Kumar, S.; Dudley, J.; Nei, M.; Tamura, K. MEGA: A biologist-centric software for evolutionary analysis of DNA and protein sequences. Brief. Bioinform. 2008, 9, 299-306.