Hepcidin in anaemic geriatric patients with non-dialysis chronic kidney disease (ND-CKD)

European Geriatric Medicine

Volumn 4, Issue 4, 2013, Pages 221-225

  Rohrig G ^a   Nobbe, C ^a   Weiss V ^a   Schulz, R J ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Keywords Non dialysis CKD Hepcidin Anemia Functional iron deficiency Elderly

Indexed keywords

C REACTIVE PROTEIN; FERRITIN; HEPCIDIN; TRANSFERRIN;

ADULT; AGED; AGED HOSPITAL PATIENT; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CORRELATION ANALYSIS; ERYTHROPOIESIS; FEMALE; GERIATRIC PATIENT; GLOMERULUS FILTRATION RATE; HUMAN; IRON DEFICIENCY ANEMIA; IRON RESTRICTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL;

EID: 84883885719     PISSN: 18787649     EISSN: 18787657     Source Type: Journal    
DOI: 10.1016/j.eurger.2013.04.010     Document Type: Article

References (29)

1. J.M. Guralnik, R.S. Eisenstaedt, L. Ferrucci, H.G. Klein, and R.C. Woodman Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia Blood 104 8 2004 2263 2268
2. F.A. Shaheen, M.Z. Souqiyyeh, B.A. Al-Attar, A. Karkar, A.M. Al Jazairi, and L.S. Badawi Prevalence of anemia in predialysis chronic kidney disease patients Saudi J Kidney Dis Transpl 22 3 2011 456 463
3. N. Voormolen, D.C. Grootendorst, T.A. Urlings, E.W. Boeschoten, Y.W. Sijpkens, and R.M. Huisman Prevalence of anemia and its impact on mortality and hospitalization rate in predialysis patients Nephron Clin Pract 115 2 2010 c133 c141
4. L. De Nicola, R. Minutolo, P. Chiodini, P. Zamboli, B. Cianciaruso, and F. Nappi Prevalence and prognosis of mild anemia in non-dialysis chronic kidney disease: a prospective cohort study in outpatient renal clinics Am J Nephrol 32 6 2010 533 540
5. D. Munikrishnappa Chronic kidney disease (CKD) in the elderly - a geriatrician's perspective Aging Male 10 3 2007 113 137
6. J.L. Abramson, C.T. Jurkovitz, V. Vaccarino, W.S. Weintraub, and W. McClellan Chronic kidney disease, anemia, and incident stroke in a middle-aged, community-based population: the ARIC Study Kidney Int 64 2 2003 610 615
7. M.L. Thorp, E.S. Johnson, X. Yang, A.F. Petrik, R. Platt, and D.H. Smith Effect of anaemia on mortality, cardiovascular hospitalizations and end-stage renal disease among patients with chronic kidney disease Nephrology (Carlton) 14 2 2009 240 246
8. D.C. Wheeler, J.N. Townend, and M.J. Landray Cardiovascular risk factors in predialysis patients: baseline data from the Chronic Renal Impairment in Birmingham (CRIB) study Kidney Int Suppl 84 2003 S201 S203
9. G.F. Strippoli, J.C. Craig, C. Manno, and F.P. Schena Hemoglobin targets for the anemia of chronic kidney disease: a meta-analysis of randomized, controlled trials J Am Soc Nephrol 15 12 2004 3154 3165
10. W.F. Keane, B.M. Brenner, D. de Zeeuw, J.P. Grunfeld, J. McGill, and W.E. Mitch The risk of developing end-stage renal disease in patients with type 2 diabetes and nephropathy: the RENAAL study Kidney Int 63 4 2003 1499 1507
11. D.S. Silverberg, D. Wexler, A. Iaina, and D. Schwartz The correction of anemia in patients with the combination of chronic kidney disease and congestive heart failure may prevent progression of both conditions Clin Exp Nephrol 13 2 2009 101 106
12. L.T. Goodnough Erythropoietin and iron-restricted erythropoiesis Exp Hematol 35 2007 167 172
13. C.Y. Hsu, C.E. McCulloch, and G.C. Curhan Epidemiology of anemia associated with chronic renal insufficiency among adults in the United States: Results from the Third National Health and Nutrition Examination Survey J Am Soc Nephrol 13 2002 504 510
14. National Kidney Foundation NKF-K/DOQI clinical practice guidelines for anemia of chronic kidney disease: update 2000 Am J Kidney Dis 37 Suppl. 1 2001 S182 S238
15. E. Nemeth Iron regulation and erythropoiesis Curr Opin Hematol 15 2008 169 175
16. G. Nicolas, L. Viatte, M. Bennoun, C. Beaumont, A. Kahn, and S. Vaulont Hepcidin, a new iron regulatory peptide Blood Cells Mol Dis 29 3 2002 327 335
17. P. Fievet, M. Coppin, F. Brazier, M. Lefèvre, R. Stephan, and R. Demontis Treatment of iron deficiency in predialysis state by low molecular weight iron dextran high doses intravenously Nephrol Ther 8 1 2012 41 46
18. W.Y. Qunibi, C. Martinez, M. Smith, J. Benjamin, A. Mangione, and S.D. Roger A randomized controlled trial comparing intravenous ferric carboxymaltose with oral iron for treatment of iron deficiency anaemia of non-dialysis- dependent chronic kidney disease patients Nephrol Dial Transplant 26 5 2011 1599 1607
19. Kidney Disease: Improving Global Outcomes (KDIGO) Anemia Work Group KDIGO Clinical Practice Guideline for Anemia in Chronic Kidney Disease Kidney Int Suppl 2 2012 279 335
20. J. Zaritsky, B. Young, H.J. Wang, M. Westerman, G. Olbina, and E. Nemeth Hepcidin - a potential novel biomarker for iron status in chronic kidney disease Clin J Am Soc Nephrol 4 2009 1051 1056
21. W.P. den Elzen, A.J. de Craen, E.T. Wiegerinck, R.G. Westendorp, D.W. Swinkels, and J. Gussekloo Plasma hepcidin levels and anemia in old age. The Leiden 85-Plus Study Haematologica 98 3 2013 448 454
22. B. Blanc Nutritional anaemias. Report of a WHO Scientific Group WHO Tech Rep Ser 405 1968 1 40
23. J. Coresh, E. Selvin, L.A. Stevens, J. Manzi, J.W. Kusek, and P. Eggers Prevalence of chronic kidney disease in the United States JAMA 298 17 2007 2038 2047
24. P. Schwarz, P. Strnad, G. von Figura, A. Janetzko, P. Krayenbühl, and G. Adler A novel monoclonal antibody immunoassay for the detection of human serum hepcidin J Gastroenterol 46 5 2011 648 656
25. T. Uehata, N. Tomosugi, T. Shoji, Y. Sakaguchi, A. Suzuki, and T. Kaneko Serum hepcidin-25 levels and anemia in non-dialysis chronic kidney disease patients: a cross-sectional study Nephrol Dial Transplant 27 3 2012 1076 1083
26. J. Malyszko, J.S. Malyszko, K. Pawlak, and M. Mysliwiec Hepcidin, iron status, and renal function in chronic renal failure, kidney transplantation, and hemodialysis Am J Hematol 81 11 2006 832 837
27. K. Niihata, N. Tomosugi, T. Uehata, T. Shoji, K. Mitsumoto, and M. Shimizu Serum hepcidin-25 levels predict the progression of renal anemia in patients with non-dialysis chronic kidney disease Nephrol Dial Transplant 2012 [Epub ahead of print]
28. D.W. Coyne Hepcidin: clinical utility as a diagnostic tool and therapeutic target Kidney Int 80 3 2011 240 244
29. H. Kulaksiz, F. Theilig, S. Bachmann, S.G. Gehrke, D. Rost, and A. Janetzko The iron-regulatory peptide hormone hepcidin: expression and cellular localization in the mammalian kidney J Endocrinol 184 2005 361 370