메뉴 건너뛰기




Volumn 15, Issue 12, 2004, Pages 3154-3165

Hemoglobin targets for the anemia of chronic kidney disease: A meta-analysis of randomized, controlled trials

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; ERYTHROPOIETIN; HEMOGLOBIN; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PLACEBO;

EID: 9644283016     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ASN.0000145436.09176.A7     Document Type: Article
Times cited : (150)

References (59)
  • 1
    • 0036154114 scopus 로고    scopus 로고
    • Epidemiology of anemia associated with chronic renal insufficiency among adults in the United States: Results from the Third National Health and Nutrition Examination Survey
    • Hsu CY, McCulloch CE, Curhan GC: Epidemiology of anemia associated with chronic renal insufficiency among adults in the United States: Results from the Third National Health and Nutrition Examination Survey. J Am Soc Nephrol 13: 504-510, 2002
    • (2002) J Am Soc Nephrol , vol.13 , pp. 504-510
    • Hsu, C.Y.1    McCulloch, C.E.2    Curhan, G.C.3
  • 5
    • 0029925557 scopus 로고    scopus 로고
    • Quality of life in predialytic uremic patients
    • Klang B, Bjorvell H, Clyne N: Quality of life in predialytic uremic patients. Qual Life Res 5: 109-116, 1996
    • (1996) Qual Life Res , vol.5 , pp. 109-116
    • Klang, B.1    Bjorvell, H.2    Clyne, N.3
  • 6
    • 0032947921 scopus 로고    scopus 로고
    • What are the short-term and long-term consequences of anaemia in CRF patients?
    • Mann JF: What are the short-term and long-term consequences of anaemia in CRF patients? Nephrol Dial Transplant 14[Suppl 2]: 29-36, 1999
    • (1999) Nephrol Dial Transplant , vol.14 , Issue.SUPPL. 2 , pp. 29-36
    • Mann, J.F.1
  • 7
    • 0026767089 scopus 로고
    • Anemia of renal failure. Use of erythropoietin
    • Humphries JE: Anemia of renal failure. Use of erythropoietin. Med Clin North Am 76: 711-725, 1992
    • (1992) Med Clin North Am , vol.76 , pp. 711-725
    • Humphries, J.E.1
  • 9
    • 85047696910 scopus 로고
    • Correction of anaemia of chronic renal failure with recombinant human erythropoietin: Safety and efficacy of one year's treatment in a European multicentre study of 150 haemodialysis-dependent patients
    • Sundal E, Kaeser U: Correction of anaemia of chronic renal failure with recombinant human erythropoietin: Safety and efficacy of one year's treatment in a European multicentre study of 150 haemodialysis-dependent patients. Nephrol Dial Transplant 4: 979-987, 1989
    • (1989) Nephrol Dial Transplant , vol.4 , pp. 979-987
    • Sundal, E.1    Kaeser, U.2
  • 10
    • 0033832718 scopus 로고    scopus 로고
    • Effects of haemoglobin normalization on quality of life and cardiovascular parameters in end-stage renal failure
    • McMahon LP, Mason K, Skinner SL, Burge CM, Grigg LE, Becker GJ: Effects of haemoglobin normalization on quality of life and cardiovascular parameters in end-stage renal failure. Nephrol Dial Transplant 15: 1425-1430, 2000
    • (2000) Nephrol Dial Transplant , vol.15 , pp. 1425-1430
    • McMahon, L.P.1    Mason, K.2    Skinner, S.L.3    Burge, C.M.4    Grigg, L.E.5    Becker, G.J.6
  • 11
    • 0035721393 scopus 로고    scopus 로고
    • Novel erythropoiesis stimulating protein for managing the anemia of chronic kidney disease
    • Nissenson AR: Novel erythropoiesis stimulating protein for managing the anemia of chronic kidney disease. Am J Kidney Dis 38: 1390-1397, 2001
    • (2001) Am J Kidney Dis , vol.38 , pp. 1390-1397
    • Nissenson, A.R.1
  • 13
    • 0025928229 scopus 로고
    • Quality of life in end-stage renal disease patients during recombinant human erythropoietin therapy
    • The Canadian Erythropoietin Study Group
    • Keown PA: Quality of life in end-stage renal disease patients during recombinant human erythropoietin therapy. The Canadian Erythropoietin Study Group. Contrib Nephrol 88: 81-86, 1991
    • (1991) Contrib Nephrol , vol.88 , pp. 81-86
    • Keown, P.A.1
  • 15
    • 0025853765 scopus 로고
    • A randomized double-blind study of recombinant human erythropoietin in anaemic hemodialysis patients
    • Canadian Erythropoietin Study Group
    • Laupacis A: A randomized double-blind study of recombinant human erythropoietin in anaemic hemodialysis patients. Canadian Erythropoietin Study Group. Transplant Proc 23: 1825-1826, 1991
    • (1991) Transplant Proc , vol.23 , pp. 1825-1826
    • Laupacis, A.1
  • 16
    • 0032572913 scopus 로고    scopus 로고
    • The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin
    • Besarab A, Bolton WK, Browne JK, Egrie JC, Nissenson AR, Okamoto DM, Schwab SJ, Goodkin DA: The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N Engl J Med 339: 584-590, 1998
    • (1998) N Engl J Med , vol.339 , pp. 584-590
    • Besarab, A.1    Bolton, W.K.2    Browne, J.K.3    Egrie, J.C.4    Nissenson, A.R.5    Okamoto, D.M.6    Schwab, S.J.7    Goodkin, D.A.8
  • 17
    • 84979426138 scopus 로고
    • Erythropoietin is a cause of access thrombosis
    • Muirhead N: Erythropoietin is a cause of access thrombosis. Semin Dial 6: 184-188, 1993
    • (1993) Semin Dial , vol.6 , pp. 184-188
    • Muirhead, N.1
  • 18
    • 0038806683 scopus 로고    scopus 로고
    • The cost-effectiveness of maintaining higher hemoglobin targets with erythropoietin in hemodialysis patients
    • Tonelli M, Winkelmayer WC, Jindal KK, Owen WF, Manns BJ: The cost-effectiveness of maintaining higher hemoglobin targets with erythropoietin in hemodialysis patients. Kidney Int 64: 295-304, 2003
    • (2003) Kidney Int , vol.64 , pp. 295-304
    • Tonelli, M.1    Winkelmayer, W.C.2    Jindal, K.K.3    Owen, W.F.4    Manns, B.J.5
  • 19
    • 0346656675 scopus 로고    scopus 로고
    • Epoetin: For better or for worse?
    • Epoetin: For better or for worse? Lancet Oncol 5: 1, 2004
    • (2004) Lancet Oncol , vol.5 , pp. 1
  • 20
    • 84921440522 scopus 로고    scopus 로고
    • Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage
    • CD000164
    • Crowther CA, Henderson-Smart DJ: Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage. Cochrane Database Syst Rev (3): CD000164, 2003
    • (2003) Cochrane Database Syst Rev , Issue.3
    • Crowther, C.A.1    Henderson-Smart, D.J.2
  • 21
    • 85047692188 scopus 로고
    • Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials
    • Schulz KF, Chalmers I, Hayes RJ, Altman DG: Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA 273: 408-412, 1995
    • (1995) JAMA , vol.273 , pp. 408-412
    • Schulz, K.F.1    Chalmers, I.2    Hayes, R.J.3    Altman, D.G.4
  • 23
    • 0026231228 scopus 로고
    • Blood pressure in hemodialysis patients during amelioration of anemia with erythropoietin
    • Abraham PA, Macres MG: Blood pressure in hemodialysis patients during amelioration of anemia with erythropoietin. J Am Soc Nephrol 2: 927-936, 1991
    • (1991) J Am Soc Nephrol , vol.2 , pp. 927-936
    • Abraham, P.A.1    Macres, M.G.2
  • 25
    • 0033002174 scopus 로고    scopus 로고
    • Effects of normal hematocrit on ambulatory blood pressure in epoetin-treated hemodialysis patients with cardiac disease
    • Berns JS, Rudnick MR, Cohen RM, Bower JD, Wood BC: Effects of normal hematocrit on ambulatory blood pressure in epoetin-treated hemodialysis patients with cardiac disease. Kidney Int 56: 253-260, 1999
    • (1999) Kidney Int , vol.56 , pp. 253-260
    • Berns, J.S.1    Rudnick, M.R.2    Cohen, R.M.3    Bower, J.D.4    Wood, B.C.5
  • 26
    • 0033042927 scopus 로고    scopus 로고
    • Safety and efficacy of erythropoietin in children with chronic renal failure
    • Brandt JR, Avner ED, Hickman RO, Watkins SL: Safety and efficacy of erythropoietin in children with chronic renal failure. Pediatr Nephrol 13: 143-147, 1999
    • (1999) Pediatr Nephrol , vol.13 , pp. 143-147
    • Brandt, J.R.1    Avner, E.D.2    Hickman, R.O.3    Watkins, S.L.4
  • 27
    • 0026523401 scopus 로고
    • Effect of erythropoietin treatment on physical exercise capacity and on renal function in predialytic uremic patients
    • Clyne N, Jogestrand T: Effect of erythropoietin treatment on physical exercise capacity and on renal function in predialytic uremic patients. Nephron 60: 390-396, 1992
    • (1992) Nephron , vol.60 , pp. 390-396
    • Clyne, N.1    Jogestrand, T.2
  • 28
    • 0033920429 scopus 로고    scopus 로고
    • Normalization of hematocrit in hemodialysis patients with cardiac disease does not increase blood pressure
    • Conlon PJ, Kovalik E, Schumm D, Minda S, Schwab SJ: Normalization of hematocrit in hemodialysis patients with cardiac disease does not increase blood pressure. Ren Fail 22: 435-444, 2000
    • (2000) Ren Fail , vol.22 , pp. 435-444
    • Conlon, P.J.1    Kovalik, E.2    Schumm, D.3    Minda, S.4    Schwab, S.J.5
  • 30
    • 0024814973 scopus 로고
    • The use of recombinant human erythropoietin in the correction of anemia in predialysis patients and its effect on renal function: A double-blind, placebo-controlled trial
    • Kleinman KS, Schweitzer SU, Perdue ST, Bleifer KH, Abels RI: The use of recombinant human erythropoietin in the correction of anemia in predialysis patients and its effect on renal function: A double-blind, placebo-controlled trial. Am J Kidney Dis 14: 486-495, 1989
    • (1989) Am J Kidney Dis , vol.14 , pp. 486-495
    • Kleinman, K.S.1    Schweitzer, S.U.2    Perdue, S.T.3    Bleifer, K.H.4    Abels, R.I.5
  • 31
    • 0030827804 scopus 로고    scopus 로고
    • Reversal of anemia by erythropoietin therapy retards the progression of chronic renal failure, especially in nondiabetic patients
    • Kuriyama S, Tomonari H, Yoshida H, Hashimoto T, Kawaguchi Y, Sakai O: Reversal of anemia by erythropoietin therapy retards the progression of chronic renal failure, especially in nondiabetic patients. Nephron 77: 176-185, 1997
    • (1997) Nephron , vol.77 , pp. 176-185
    • Kuriyama, S.1    Tomonari, H.2    Yoshida, H.3    Hashimoto, T.4    Kawaguchi, Y.5    Sakai, O.6
  • 32
    • 0024581871 scopus 로고
    • Recombinant human erythropoietin treatment in pre-dialysis patients. A double-blind placebo-controlled trial
    • Lim VS, DeGowin RL, Zavala D, Kirchner PT, Abels R, Perry P, Fangman J: Recombinant human erythropoietin treatment in pre-dialysis patients. A double-blind placebo-controlled trial. Ann Intern Med 110: 108-114, 1989
    • (1989) Ann Intern Med , vol.110 , pp. 108-114
    • Lim, V.S.1    DeGowin, R.L.2    Zavala, D.3    Kirchner, P.T.4    Abels, R.5    Perry, P.6    Fangman, J.7
  • 33
    • 0027489009 scopus 로고
    • Non-cardiac benefits of human recombinant erythropoietin in end stage renal failure and anaemia
    • Morris KP, Sharp J, Watson S, Coulthard MG: Non-cardiac benefits of human recombinant erythropoietin in end stage renal failure and anaemia. Arch Dis Child 69: 580-586, 1993
    • (1993) Arch Dis Child , vol.69 , pp. 580-586
    • Morris, K.P.1    Sharp, J.2    Watson, S.3    Coulthard, M.G.4
  • 34
    • 0028945387 scopus 로고
    • Health-related quality of life associated with recombinant human erythropoietin therapy for predialysis chronic renal disease patients
    • Revicki DA, Brown RE, Feeny DH, Henry D, Teehan BP, Rudnick MR, Benz RL: Health-related quality of life associated with recombinant human erythropoietin therapy for predialysis chronic renal disease patients. Am J Kidney Dis 25: 548-554, 1995
    • (1995) Am J Kidney Dis , vol.25 , pp. 548-554
    • Revicki, D.A.1    Brown, R.E.2    Feeny, D.H.3    Henry, D.4    Teehan, B.P.5    Rudnick, M.R.6    Benz, R.L.7
  • 35
    • 0027724073 scopus 로고
    • Analysis of heart morphology and function following erythropoietin treatment of anemic dialysis patients
    • Sikole A, Polenakovic M, Spirovska V, Polenakovic B, Masin G: Analysis of heart morphology and function following erythropoietin treatment of anemic dialysis patients. Artif Organs 17: 977-984, 1993
    • (1993) Artif Organs , vol.17 , pp. 977-984
    • Sikole, A.1    Polenakovic, M.2    Spirovska, V.3    Polenakovic, B.4    Masin, G.5
  • 36
    • 0025302489 scopus 로고
    • Early intervention with recombinant human erythropoietin therapy
    • Teehan BP, Benz RL, Sigler MH, Brown JM: Early intervention with recombinant human erythropoietin therapy. Semin Nephrol 10: 28-34, 1990
    • (1990) Semin Nephrol , vol.10 , pp. 28-34
    • Teehan, B.P.1    Benz, R.L.2    Sigler, M.H.3    Brown, J.M.4
  • 37
    • 0025077010 scopus 로고
    • Treatment of the anemia of chronic renal failure with subcutaneous recombinant human erythropoietin
    • Watson AJ, Gimenez LF, Cotton S, Walser M, Spivak JL: Treatment of the anemia of chronic renal failure with subcutaneous recombinant human erythropoietin. Am J Med 89: 432-435, 1990
    • (1990) Am J Med , vol.89 , pp. 432-435
    • Watson, A.J.1    Gimenez, L.F.2    Cotton, S.3    Walser, M.4    Spivak, J.L.5
  • 38
    • 0025892745 scopus 로고
    • Effect of recombinant human erythropoietin therapy on blood pressure in hemodialysis patients
    • Canadian Erythropoietin Study Group
    • Effect of recombinant human erythropoietin therapy on blood pressure in hemodialysis patients. Canadian Erythropoietin Study Group. Am J Nephrol 11: 23-26, 1991
    • (1991) Am J Nephrol , vol.11 , pp. 23-26
  • 39
    • 0034055969 scopus 로고    scopus 로고
    • Normalization of hematocrit in hemodialysis patients does not affect silent ischemia
    • Conlon PJ, Kovalik E, Schumm D, Minda S, Schwab SJ: Normalization of hematocrit in hemodialysis patients does not affect silent ischemia. Ren Fail 22: 205-211, 2000
    • (2000) Ren Fail , vol.22 , pp. 205-211
    • Conlon, P.J.1    Kovalik, E.2    Schumm, D.3    Minda, S.4    Schwab, S.J.5
  • 40
    • 0025373361 scopus 로고
    • Association between recombinant human erythropoietin and quality of life and exercise capacity of patients receiving haemodialysis
    • Canadian Erythropoietin Study Group
    • Association between recombinant human erythropoietin and quality of life and exercise capacity of patients receiving haemodialysis. Canadian Erythropoietin Study Group. BMJ 300: 573-578, 1990
    • (1990) BMJ , vol.300 , pp. 573-578
  • 42
    • 0037317068 scopus 로고    scopus 로고
    • A randomized controlled trial of haemoglobin normalization with epoetin alfa in pre-dialysis and dialysis patients
    • Furuland H, Linde T, Ahlmen J, Christensson A, Strombom U, Danielson BG: A randomized controlled trial of haemoglobin normalization with epoetin alfa in pre-dialysis and dialysis patients. Nephrol Dial Transplant 18: 353-361, 2003
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 353-361
    • Furuland, H.1    Linde, T.2    Ahlmen, J.3    Christensson, A.4    Strombom, U.5    Danielson, B.G.6
  • 44
    • 0032916267 scopus 로고    scopus 로고
    • Normalization of haemoglobin: Why not?
    • Jacobs C: Normalization of haemoglobin: Why not? Nephrol Dial Transplant 14[Suppl 2]: 75-79, 1999
    • (1999) Nephrol Dial Transplant , vol.14 , Issue.SUPPL. 2 , pp. 75-79
    • Jacobs, C.1
  • 45
    • 0036655023 scopus 로고    scopus 로고
    • Should hemoglobin be normalized in uremic patients?
    • Foley RN: Should hemoglobin be normalized in uremic patients? Clin Nephrol 58[Suppl 1]: S58-S61, 2002
    • (2002) Clin Nephrol , vol.58 , Issue.SUPPL. 1
    • Foley, R.N.1
  • 46
    • 0033925188 scopus 로고    scopus 로고
    • The optimal target hemoglobin
    • Ritz E, Schwenger V: The optimal target hemoglobin. Semin Nephrol 20: 382-386, 2000
    • (2000) Semin Nephrol , vol.20 , pp. 382-386
    • Ritz, E.1    Schwenger, V.2
  • 47
    • 0032401967 scopus 로고    scopus 로고
    • Heterogeneity of the baseline risk within patient populations of clinical trials: A proposed evaluation algorithm
    • Ioannidis JP, Lau J: Heterogeneity of the baseline risk within patient populations of clinical trials: A proposed evaluation algorithm. Am J Epidemiol 148: 1117-1126, 1998
    • (1998) Am J Epidemiol , vol.148 , pp. 1117-1126
    • Ioannidis, J.P.1    Lau, J.2
  • 48
    • 0036244550 scopus 로고    scopus 로고
    • Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades
    • Chong ZZ, Kang JQ, Maiese K: Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades. J Cereb Blood Flow Metab 22: 503-514, 2002
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 503-514
    • Chong, Z.Z.1    Kang, J.Q.2    Maiese, K.3
  • 49
    • 0025718847 scopus 로고
    • Erythropoietin and spontaneous platelet aggregation in haemodialysis patients
    • Taylor JE, Henderson IS, Stewart WK, Belch JJ: Erythropoietin and spontaneous platelet aggregation in haemodialysis patients. Lancer 338: 1361-1362, 1991
    • (1991) Lancer , vol.338 , pp. 1361-1362
    • Taylor, J.E.1    Henderson, I.S.2    Stewart, W.K.3    Belch, J.J.4
  • 50
    • 0041976976 scopus 로고    scopus 로고
    • Breast cancer trial with erythropoietin terminated unexpectedly
    • Leyland-Jones B, BEST Investigators and Study Group: Breast cancer trial with erythropoietin terminated unexpectedly. Lancet Oncol 4: 459-460, 2003
    • (2003) Lancet Oncol , vol.4 , pp. 459-460
    • Leyland-Jones, B.1
  • 55
    • 0012444787 scopus 로고    scopus 로고
    • Rockville, MD, Agency for Healthcare Research and Quality (Prepared by the Blue Cross and Blue Shield Association Technology Evaluation Center under contract No. 290-97-0015; AHRQ Publication No. 01-3016)
    • Flamm CR, Aronson N, Bohn R: Use of Epoetin for Anemia in Chronic Renal Failure. Evidence Report/Technology Assessment N9.29, Rockville, MD, Agency for Healthcare Research and Quality, 2001 (Prepared by the Blue Cross and Blue Shield Association Technology Evaluation Center under contract No. 290-97-0015; AHRQ Publication No. 01-3016)
    • (2001) Use of Epoetin for Anemia in Chronic Renal Failure. Evidence Report/Technology Assessment N9.29
    • Flamm, C.R.1    Aronson, N.2    Bohn, R.3
  • 56
    • 0032246766 scopus 로고    scopus 로고
    • Trends in anemia treatment with erythropoietin usage and patient outcomes
    • Collins AJ, Ma JZ, Xia A, Ebben J: Trends in anemia treatment with erythropoietin usage and patient outcomes. Am J Kidney Dis 32: S133-S141, 1998
    • (1998) Am J Kidney Dis , vol.32
    • Collins, A.J.1    Ma, J.Z.2    Xia, A.3    Ebben, J.4
  • 57
    • 0018736142 scopus 로고
    • Bias in analytic research
    • Sackett DL: Bias in analytic research. J Chronic Dis 32: 51-63, 1979
    • (1979) J Chronic Dis , vol.32 , pp. 51-63
    • Sackett, D.L.1
  • 58
    • 0036236303 scopus 로고    scopus 로고
    • Effects of increased peritoneal clearances on mortality rates in peritoneal dialysis: ADEMEX, a prospective, randomized, controlled trial
    • Paniagua R, Amato D, Vonesh E, Correa-Rotter R, Ramos A, Moran J, Mujais S, Mexican Nephrology Collaborative Study Group: Effects of increased peritoneal clearances on mortality rates in peritoneal dialysis: ADEMEX, a prospective, randomized, controlled trial. J Am Soc Nephrol 13: 1307-1320, 2002
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1307-1320
    • Paniagua, R.1    Amato, D.2    Vonesh, E.3    Correa-Rotter, R.4    Ramos, A.5    Moran, J.6    Mujais, S.7
  • 59
    • 0032926635 scopus 로고    scopus 로고
    • Lessons from the Hemodialysis (HEMO) Study: An improved measure of the actual hemodialysis dose
    • Depner T, Beck G, Daugirdas J, Kusek J, Eknoyan G: Lessons from the Hemodialysis (HEMO) Study: An improved measure of the actual hemodialysis dose. Am J Kidney Dis 33: 142-149, 1999
    • (1999) Am J Kidney Dis , vol.33 , pp. 142-149
    • Depner, T.1    Beck, G.2    Daugirdas, J.3    Kusek, J.4    Eknoyan, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.