Rapid Fc glycosylation analysis of Fc fusions with IdeS and liquid chromatography mass spectrometry

mAbs

Volumn 5, Issue 5, 2013, Pages 641-645

  Lynaugh, Heather ^a   Li, Huijuan ^a   Gong, Bing ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Fc fusion protein; Glycosylation analysis; IdeS protease; LC MS

Indexed keywords

ABATACEPT; BACTERIAL ENZYME; IMMUNOGLOBULIN DEGRADING ENZYME; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; GLYCOSYLATION; HINGE REGION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR RECOGNITION; STREPTOCOCCUS PYOGENES;

FC FUSION PROTEIN; GLYCOSYLATION ANALYSIS; IDES PROTEASE; LC-MS;

ANIMALS; BACTERIAL PROTEINS; BINDING SITES; CHO CELLS; CHROMATOGRAPHY, LIQUID; CRICETINAE; CRICETULUS; CYSTEINE ENDOPEPTIDASES; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; MASS SPECTROMETRY; PICHIA; POLYSACCHARIDES; RECOMBINANT FUSION PROTEINS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84883859087     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.25302     Document Type: Article

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