Role and mechanism of tissue plasminogen activator in venous wall fibrosis remodeling after deep venous thrombosis via the glycogen synthase kinase-3 beta signaling pathway

Journal of Surgical Research

Volumn 184, Issue 2, 2013, Pages 1182-1195

  Yin, Minyi ^a,b   Tian, Shuo ^a,b   Huang, Xintian ^a,b   Huang, Ying ^a,b   Jiang, Mier ^a,b  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Deep venous thrombosis; GSK3 ; tPA; Vein wall remodeling

Indexed keywords

ALTEPLASE; COLLAGEN TYPE 1; CYCLIN D1; ENHANCED GREEN FLUORESCENT PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATE BUFFERED SALINE; PLASMID VECTOR; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL CULTURE; CELL CYCLE PROGRESSION; COLLAGEN DEGRADATION; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMORAL VEIN; FLOW CYTOMETRY; GENE SWITCHING; GENETIC TRANSFECTION; HISTOPATHOLOGY; IN VIVO STUDY; INTIMA; MALE; NONHUMAN; PHENOTYPE; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TUNICA MEDIA; UPREGULATION; VASCULAR SMOOTH MUSCLE; VEIN LIGATION; VEIN WALL; VENOUS STASIS; WESTERN BLOTTING;

DEEP VENOUS THROMBOSIS; GSK3Β; TPA; VEIN WALL REMODELING;

ANIMALS; CELLS, CULTURED; COLLAGEN; DISEASE MODELS, ANIMAL; FEMORAL VEIN; FIBROSIS; GLYCOGEN SYNTHASE KINASE 3; MALE; MAP KINASE SIGNALING SYSTEM; MUSCLE, SMOOTH, VASCULAR; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TISSUE PLASMINOGEN ACTIVATOR; VENOUS THROMBOSIS;

EID: 84883852006     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.03.100     Document Type: Article

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