In vivo effects of a new dentifrice containing 1.5% arginine and 1450 ppm fluoride on plaque metabolism

Journal of Clinical Dentistry

Volumn 24, Issue SPEC.ISS.A, 2013, Pages

  Wolff, M ^a   Corby, P ^a   Klaczany, G ^a   Santarpia, P ^b   Lavender, S ^b   Gittins, E ^b   Vandeven, M ^b   Cummins, D ^b   Sullivan, R ^b  

^a NEW YORK UNIVERSITY COLLEGE OF DENTISTRY   (United States)

^b Oral Care Research and Development   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; ANTICARIES AGENT; ARGININE; CALCIUM; FLUORIDE; FLUOROPHOSPHATE; LACTIC ACID; PHOSPHATE; SILICON DIOXIDE; SODIUM FLUORIDE; SUCROSE; TOOTHPASTE;

ARTICLE; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FOLLOW UP; HUMAN; METABOLISM; PH; RANDOMIZED CONTROLLED TRIAL; TOOTH PLAQUE;

AMMONIA; ARGININE; CALCIUM; CARIOSTATIC AGENTS; DENTAL PLAQUE; DENTIFRICES; DOUBLE-BLIND METHOD; FLUORIDES; FOLLOW-UP STUDIES; HUMANS; HYDROGEN-ION CONCENTRATION; LACTIC ACID; PHOSPHATES; SILICON DIOXIDE; SODIUM FLUORIDE; SUCROSE;

EID: 84883830153     PISSN: 08958831     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Tanzer JM, Krichevsky MI, Keyes PH. The metabolic fate of glucose catabolized by a washed stationary phase caries-conducive steptococcus. Caries Res 1969;3:167-77.
2. Loesche W. Role of Streptococcus mutans in human dental decay. Microbiol Rev 1986;50:353-80. (Pubitemid 17202894)
3. Dashper SG, Reynolds EC. Lactic acid excretion by Streptococcus mutans. Microbiol 1996;142:33-9. (Pubitemid 26032043)
4. Law V, Seow WK, Townsend G. Factors influencing oral colonization of mutans streptococci in young children. Aust Dent J 2007;52:93-100.
5. Kleinberg I. A new saliva based anticaries composition. Dent Today 1999;18:98-103.
6. Zhang JZ, Harper DS, Vogel GL, Schumacher G. Effect of an essential oil mouthrinse, with and without fluoride, on plaque metabolic acid production and pH after a sucrose challenge. Caries Res 2004;38:537-41. (Pubitemid 39482557)
7. Carter WMJ, Dunn J K, Fosdick LS, Moore BW. The formation of lactic acid in dental plaque. I. Caries-active individuals. J Dent Res 1956;35: 778-85.
8. Margolis HC, Moreno EC. Composition and cariogenic potential of dental plaque fluid. Crit Rev Oral Biol Med 1994;5:1 -25.
9. Shimizu K, Igarashi K, Takahashi N. Chairside evaluation of pH-lowering activity and lactic acid production of dental plaque: Correlation with caries experience and incidence in preschool children. Quintessence Int 2008;39:151-8.
10. Rolla G, Scheie AA, Ciardi JE. Role of sucrose in plaque formation. Scand J Dent Res 1985;93:105-11.
11. Bender GR, Thibodeau ET, Marquis RT. Reduction of acidurance of streptococcal growth and glycolysis by fluoride and gramicidin. J Dent Res 1985;64:90-5. (Pubitemid 15102864)
12. Aoba T. The effect of fluoride on apatite structure and growth. Crit Rev Oral Biol Med 1997;8:136-53. (Pubitemid 27217165)
13. Robinson C, Shore RC, Brooks SJ, Stafford S, Wood SR, Kirkham J. The chemistry of enamel caries. Crit Rev Oral Biol Med 2000; 11:481-95. (Pubitemid 32003258)
14. Bratthall D, Hänsel-Petersson G, Sundberg H. Reasons for the caries decline: What do the experts believe? Eur J Oral Sci 1996; 104:416-22.
15. Cummins D. Dental caries: A disease that remains a public health concern in the 21st century-the exploration of a breakthrough technology for caries prevention. J Clin Dent 2013;24(Spec Iss A):A1-14.
16. Burne RA, Marquis RE. Alkali production by oral bacteria and protection against dental caries. FEMS Microbiol Lett 2000; 193:1-6.
17. Liu S, Pritchard GG, Hardman MJ, Pilone G. Occurrence of arginine deiminase pathway enzymes in arginine catabolism by wine lactic acid bacteria. Appl Environ Microbiol 1995;61:310-6.
18. Wijeyeweera R L, Kleinberg I. Arginolytic and ureolytic activities of pure cultures of human oral bacteria and their effects on the pH response of salivary sediment and dental plaque in vitro. Arch Oral Biol 1989;34:43-53.
19. Casiano-Colón A, Marquis RE. Role of the arginine deiminase system in protecting oral bacteria and an enzymatic basis for acid tolerance. Appl Environ Microbiol 1988;54:1318-24.
20. van Wuyckhuyse BC, Perinpanayagam HE, Bevacqua D, Raubertas RF, Billings RJ, Bowen WH, Tabak LA. Association of free arginine and lysine concentrations in human parotid saliva with caries experience. J Dent Res 1995;74:686-90.
21. Kleinberg I. A mixed-bacteria ecological approach to understanding the role of the oral bacteria in dental caries causation: an alternative to Streptococcus mutans and the specific-plaque hypothesis. Crit Rev Oral Biol Med 2002;13:108-25. (Pubitemid 34791212)
22. Acevedo AM, Machado C, Rivera LE, Wolff M, Kleinberg I. The inhibitory effect of an arginine bicarbonate/calcium carbonate (CaviStat)-containing dentifrice on the development of dental caries in Venezuelan school children. J Clin Dent 2005; 16:63-70. (Pubitemid 41527051)
23. Yin W, Hu DY, Fan X, Feng Y, Zhang YP, Cummins D, Mateo LR, Pretty IA, Ellwood RP. A clinical investigation using quantitative light-induced fluorescence (QLF) of the anticaries efficacy of a dentifrice containing 1.5% arginine and 1450 ppm fluoride as sodium monofluorophosphate. J Clin Dent 2013;24(Spec Iss A):A 15-22.
24. Yin W, Hu DY, Li X, Fan X, Zhang YP, Pretty IA, Mateo LR, Cummins D, Ellwood RP. The anti-caries efficacy of a dentifrice containing 1.5% arginine and 1450 ppm fluoride as sodium monofluorophosphate assessed using quantitative light-induced fluorescence (QLF). J Dent 2013;41(Suppl 2):22-8.
25. Srisilapanan P, Korwanich N, Yin W, Cheunsuwonkul C, Mateo LR, Zhang YP, Cummins D, Ellwood RP. Comparison of the efficacy of a dentifrice containing 1.5% arginine and 1450 ppm fluoride to a dentifrice containing 1450 ppm fluoride alone in the management of early coronal caries as assessed using quantitative light-induced fluorescence. J Dent 2013;41(Suppl 2):29-34.
26. Hu DY, Yin W, Li X, Feng Y, Zhang YP, Cummins D, Mateo LR, Ellwood RP. A clinical investigation of the efficacy of a dentifrice containing 1.5% arginine and 1450 ppm fluoride, as sodium monofluorophosphate in a calcium base, on primary root caries. J Clin Dent 2013;24(Spec Iss A):A23-31.
27. Souza M LR, Cury JA, Tenuta LMA, Zhang YP, Mateo LR, Cummins D, Ellwood RP. Comparing the efficacy of a dentifrice containing 1.5% arginine and 1450 ppm fluoride to a dentifrice containing 1450 ppm fluoride alone in the management of primary root caries. J Dent 2013;41 (Suppl 2):35-41.
28. Kraivaphan P, Amomchat C, Triratana T, Mateo LR, Ellwood R, Cummins D, DeVizio W, Zhang YP. Two-year caries clinical study of the efficacy of novel dentifrices containing 1.5% arginine, an insoluble calcum compound and 1450 ppm fluoride. Accepted for publication in Caries Res.
29. Damen JJ, Buijs MJ, ten Cate JM. Acidogenicity of buccal plaque after a single rinse with amine fiuoride-stannous fluoride mouthrinse solution. Caries Res 2002;36:53-7.
30. Naini A, Mandel I. Plaque ammonia production in caries resistant and caries susceptible adults. J Dent Res 1989;68(Spec Iss):318.
31. Gerardu VA, Buijs M, van Loveren C, ten Cate JM. Plaque formation and lactic acid production after the use of amine fluoride/stannous fluoride mouthrinse. Eur J Oral Sci 2007; 115:148-52.
32. Izco JM, Tormo M, Jimenez-Flores R. Rapid simultaneous determination of organic acids, free amino acids, and lactose in cheese by capillary electrophoresis. J Dairy Sci 2002;85:2122-9. (Pubitemid 38572129)
33. Cantore R, Petrou I, Lavender S, Santarpia P, Liu Z, Gittins E, Vandeven M, Cummins D, Sullivan R, Utgikar N. In situ clinical effects of new dentifrices containing 1.5% arginine and fluoride on enamel de- and remineral ization and plaque metabolism. J Clin Dent 2013;24(Spec Iss A):A3244.
34. Jenkins G: The Physiology and Biochemistry of the Mouth. 4th ed. Blackwell Scientific Publications, 1978.
35. Burne RA, Marquis RE. Alkali production by oral bacteria and protection against dental caries. FEMS Microbiol Lett 2000; 193:1 -6.
36. Burne RA, Zeng L, Ahn SJ, Palmer SR, Liu Y, Lefebure T, Stanhope MJ, Nascimento MM. Progress dissecting the oral microbiome in caries and health. Adv Dent Res 2012;24:77-80.
37. Shu M, Morou-Bermudez E, Suarez-Perez E, Rivera-Miranda C, Browngardt CM, Chen YY, Magnusson I, Burne RA. The relationship between dental caries status and dental plaque urease activity. Oral Microbiol Immunol 2007;22:61-6. (Pubitemid 46096197)
38. Morou-Bermudez E, Elias-Boneta A, Billings RJ, Burne RA, GarciaRivas V, Brignoni-Nazario V, Suarez-Perez E. Urease activity in dental plaque and saliva of children during a three-year study period and its relationship with other caries risk factors. Arch Oral Biol 201;56:1282-9.
39. Nascimento MM, Gordan V, Garvan CW, Browngardt CM, Burne RA. Correlations of oral bacteria arginine and urea catabolism with caries experience. Oral Micro Immun 2009;24:89-95.
40. Gordan VV, Garvan CW, Ottenga, Schulte R, Harris PA, Mc Edward, Magnusson I. Could alkali production be considered an approach for caries control? Caries Res 2010;44:547-54.
41. Nascimento MM, personal communication.
42. Autio-Gold J. The role of Chlorhexidine in caries prevention. Oper Dent 2008;33:710-6.
43. Zhang Q, van Palenstein Helderman WH, van't Hof MA, Truin GJ. Chlorhexidine varnish for preventing dental caries in children, adolescents and young adults: a systematic review. Eur J Oral Sci 2006; 114:449-55. (Pubitemid 44893344)
44. Twetman S. Antimicrobials in future caries control? A review with special reference to Chlorhexidine treatment. Caries Res 2004;38:223-9. (Pubitemid 38716213)