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Volumn 22, Issue 3, 2013, Pages

Genomic and molecular aberrations in malignant peripheral nerve sheath tumor and their roles in personalized target therapy

Author keywords

Genetic aberration; Malignant peripheral nerve sheath tumor; Microarray based comparative genomic hybridization; Personalized medicine; Target therapy

Indexed keywords

BINDING PROTEIN; BIRC5 PROTEIN; COLLAGENASE 3; CYCLIN DEPENDENT KINASE 6; DNA TOPOISOMERASE (ATP HYDROLYSING) A; E1A ENHANCER BINDING PROTEIN; EARLY GROWTH RESPONSE FACTOR 1; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUTATHIONE TRANSFERASE T1; LYSYL OXIDASE LIKE 2 PROTEIN; MATRIX METALLOPROTEINASE 15; PEPTIDES AND PROTEINS; PROTEIN BCL 3; PROTEIN KINASE B BETA; PROTEIN LYSINE 6 OXIDASE; PROTEIN MSH2; PROTEIN P53; SCATTER FACTOR RECEPTOR; SOMATOMEDIN C; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; UVOMORULIN; XERODERMA PIGMENTOSUM GROUP D PROTEIN;

EID: 84883824488     PISSN: 09607404     EISSN: 18793320     Source Type: Journal    
DOI: 10.1016/j.suronc.2013.06.003     Document Type: Review
Times cited : (12)

References (34)
  • 1
    • 34548415523 scopus 로고    scopus 로고
    • Malignant peripheral nerve sheath tumors
    • G. Gupta, and A. Maniker Malignant peripheral nerve sheath tumors Neurosurg Focus 22 2007 E12
    • (2007) Neurosurg Focus , vol.22 , pp. 12
    • Gupta, G.1    Maniker, A.2
  • 2
    • 33646593182 scopus 로고    scopus 로고
    • Malignant peripheral nerve sheath tumors: An update
    • B. Fuchs, R.J. Spinner, and M.G. Rock Malignant peripheral nerve sheath tumors: an update J Surg Orthop Adv 14 2005 168 174
    • (2005) J Surg Orthop Adv , vol.14 , pp. 168-174
    • Fuchs, B.1    Spinner, R.J.2    Rock, M.G.3
  • 3
    • 13644258035 scopus 로고    scopus 로고
    • Molecular profiling of malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1, based on large-scale real-time RT-PCR
    • P. Levy, D. Vidaud, K. Leroy, I. Laurendeau, J. Wechsler, and G. Bolasco Molecular profiling of malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1, based on large-scale real-time RT-PCR Mol Cancer 3 2004 20
    • (2004) Mol Cancer , vol.3 , pp. 20
    • Levy, P.1    Vidaud, D.2    Leroy, K.3    Laurendeau, I.4    Wechsler, J.5    Bolasco, G.6
  • 4
    • 79953331217 scopus 로고    scopus 로고
    • Array-based comparative genomic hybridization identifies CDK4 and FOXM1 alterations as independent predictors of survival in malignant peripheral nerve sheath tumor
    • J. Yu, H. Deshmukh, J.E. Payton, C. Dunham, B.W. Scheithauer, and T. Tihan Array-based comparative genomic hybridization identifies CDK4 and FOXM1 alterations as independent predictors of survival in malignant peripheral nerve sheath tumor Clin Cancer Res 17 2011 1924 1934
    • (2011) Clin Cancer Res , vol.17 , pp. 1924-1934
    • Yu, J.1    Deshmukh, H.2    Payton, J.E.3    Dunham, C.4    Scheithauer, B.W.5    Tihan, T.6
  • 5
    • 80052207613 scopus 로고    scopus 로고
    • Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma
    • S. Ugras, E. Brill, A. Jacobsen, M. Hafner, N.D. Socci, and P.L. Decarolis Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma Cancer Res 71 2011 5659 5669
    • (2011) Cancer Res , vol.71 , pp. 5659-5669
    • Ugras, S.1    Brill, E.2    Jacobsen, A.3    Hafner, M.4    Socci, N.D.5    Decarolis, P.L.6
  • 6
    • 47649124124 scopus 로고    scopus 로고
    • A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome
    • M. Sultan, M.H. Schulz, H. Richard, A. Magen, A. Klingenhoff, and M. Scherf A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome Science 321 2008 956 960
    • (2008) Science , vol.321 , pp. 956-960
    • Sultan, M.1    Schulz, M.H.2    Richard, H.3    Magen, A.4    Klingenhoff, A.5    Scherf, M.6
  • 7
    • 79958239179 scopus 로고    scopus 로고
    • Lessons from the deep study of rare tumours
    • D.M. Thomas Lessons from the deep study of rare tumours J Pathol 224 2011 306 308
    • (2011) J Pathol , vol.224 , pp. 306-308
    • Thomas, D.M.1
  • 9
    • 39749203515 scopus 로고    scopus 로고
    • High-resolution DNA copy number profiling of malignant peripheral nerve sheath tumors using targeted microarray-based comparative genomic hybridization
    • K.K. Mantripragada, G. Spurlock, L. Kluwe, N. Chuzhanova, R.E. Ferner, and I.M. Frayling High-resolution DNA copy number profiling of malignant peripheral nerve sheath tumors using targeted microarray-based comparative genomic hybridization Clin Cancer Res 14 2008 1015 1024
    • (2008) Clin Cancer Res , vol.14 , pp. 1015-1024
    • Mantripragada, K.K.1    Spurlock, G.2    Kluwe, L.3    Chuzhanova, N.4    Ferner, R.E.5    Frayling, I.M.6
  • 10
    • 0344224273 scopus 로고    scopus 로고
    • Analysis of chromosomal imbalances in sporadic and NF1-associated peripheral nerve sheath tumors by comparative genomic hybridization
    • G. Mechtersheimer, M. Otano-Joos, S. Ohl, A. Benner, T. Lehnert, and F. Willeke Analysis of chromosomal imbalances in sporadic and NF1-associated peripheral nerve sheath tumors by comparative genomic hybridization Genes Chromosomes Cancer 25 1999 362 369
    • (1999) Genes Chromosomes Cancer , vol.25 , pp. 362-369
    • Mechtersheimer, G.1    Otano-Joos, M.2    Ohl, S.3    Benner, A.4    Lehnert, T.5    Willeke, F.6
  • 11
    • 84055222094 scopus 로고    scopus 로고
    • Genomic and molecular characterization of malignant peripheral nerve sheath tumor identifies the IGF1R pathway as a primary target for treatment
    • J. Yang, A. Ylipaa, Y. Sun, H. Zheng, K. Chen, and M. Nykter Genomic and molecular characterization of malignant peripheral nerve sheath tumor identifies the IGF1R pathway as a primary target for treatment Clin Cancer Res 17 2011 7563 7573
    • (2011) Clin Cancer Res , vol.17 , pp. 7563-7573
    • Yang, J.1    Ylipaa, A.2    Sun, Y.3    Zheng, H.4    Chen, K.5    Nykter, M.6
  • 12
    • 0345552243 scopus 로고    scopus 로고
    • Genomic imbalances of 7p and 17q in malignant peripheral nerve sheath tumors are clinically relevant
    • H. Schmidt, P. Wurl, H. Taubert, A. Meye, M. Bache, and H.J. Holzhausen Genomic imbalances of 7p and 17q in malignant peripheral nerve sheath tumors are clinically relevant Genes Chromosomes Cancer 25 1999 205 211
    • (1999) Genes Chromosomes Cancer , vol.25 , pp. 205-211
    • Schmidt, H.1    Wurl, P.2    Taubert, H.3    Meye, A.4    Bache, M.5    Holzhausen, H.J.6
  • 13
    • 0036242757 scopus 로고    scopus 로고
    • Frequent genomic imbalances in chromosomes 17, 19, and 22q in peripheral nerve sheath tumours detected by comparative genomic hybridization analysis
    • T. Koga, H. Iwasaki, M. Ishiguro, A. Matsuzaki, and M. Kikuchi Frequent genomic imbalances in chromosomes 17, 19, and 22q in peripheral nerve sheath tumours detected by comparative genomic hybridization analysis J Pathol 197 2002 98 107
    • (2002) J Pathol , vol.197 , pp. 98-107
    • Koga, T.1    Iwasaki, H.2    Ishiguro, M.3    Matsuzaki, A.4    Kikuchi, M.5
  • 14
    • 33748544613 scopus 로고    scopus 로고
    • A cytogenetic analysis in two cases of malignant peripheral nerve sheath tumor showing hypodiploid karyotype
    • M. Ishiguro, H. Iwasaki, M. Takeshita, Y. Hirose, and Y. Kaneko A cytogenetic analysis in two cases of malignant peripheral nerve sheath tumor showing hypodiploid karyotype Oncol Rep 16 2006 225 232
    • (2006) Oncol Rep , vol.16 , pp. 225-232
    • Ishiguro, M.1    Iwasaki, H.2    Takeshita, M.3    Hirose, Y.4    Kaneko, Y.5
  • 15
    • 0035395754 scopus 로고    scopus 로고
    • Cytogenetic characterization of six malignant peripheral nerve sheath tumors: Comparison of karyotyping and comparative genomic hybridization
    • H. Schmidt, H. Taubert, P. Wurl, M. Bache, F. Bartel, and H.J. Holzhausen Cytogenetic characterization of six malignant peripheral nerve sheath tumors: comparison of karyotyping and comparative genomic hybridization Cancer Genet Cytogenet 128 2001 14 23
    • (2001) Cancer Genet Cytogenet , vol.128 , pp. 14-23
    • Schmidt, H.1    Taubert, H.2    Wurl, P.3    Bache, M.4    Bartel, F.5    Holzhausen, H.J.6
  • 17
    • 31544475397 scopus 로고    scopus 로고
    • An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model
    • K.M. Reilly, K.W. Broman, R.T. Bronson, S. Tsang, D.A. Loisel, and E.S. Christy An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model Cancer Res 66 2006 62 68
    • (2006) Cancer Res , vol.66 , pp. 62-68
    • Reilly, K.M.1    Broman, K.W.2    Bronson, R.T.3    Tsang, S.4    Loisel, D.A.5    Christy, E.S.6
  • 18
    • 0035164154 scopus 로고    scopus 로고
    • Biallelic inactivation of TP53 rarely contributes to the development of malignant peripheral nerve sheath tumors
    • R.A. Lothe, B. Smith-Sorensen, M. Hektoen, A.E. Stenwig, N. Mandahl, and G. Saeter Biallelic inactivation of TP53 rarely contributes to the development of malignant peripheral nerve sheath tumors Genes Chromosomes Cancer 30 2001 202 206
    • (2001) Genes Chromosomes Cancer , vol.30 , pp. 202-206
    • Lothe, R.A.1    Smith-Sorensen, B.2    Hektoen, M.3    Stenwig, A.E.4    Mandahl, N.5    Saeter, G.6
  • 19
    • 64949185318 scopus 로고    scopus 로고
    • Molecular characterization of permanent cell lines from primary, metastatic and recurrent malignant peripheral nerve sheath tumors (MPNST) with underlying neurofibromatosis-1
    • Y. Fang, A. Elahi, R.C. Denley, P.H. Rao, M.F. Brennan, and S.C. Jhanwar Molecular characterization of permanent cell lines from primary, metastatic and recurrent malignant peripheral nerve sheath tumors (MPNST) with underlying neurofibromatosis-1 Anticancer Res 29 2009 1255 1262
    • (2009) Anticancer Res , vol.29 , pp. 1255-1262
    • Fang, Y.1    Elahi, A.2    Denley, R.C.3    Rao, P.H.4    Brennan, M.F.5    Jhanwar, S.C.6
  • 20
    • 33646753630 scopus 로고    scopus 로고
    • Chromosomal imbalances in malignant peripheral nerve sheath tumor detected by metaphase and microarray comparative genomic hybridization
    • Y. Nakagawa, A. Yoshida, K. Numoto, T. Kunisada, D. Wai, and N. Ohata Chromosomal imbalances in malignant peripheral nerve sheath tumor detected by metaphase and microarray comparative genomic hybridization Oncol Rep 15 2006 297 303
    • (2006) Oncol Rep , vol.15 , pp. 297-303
    • Nakagawa, Y.1    Yoshida, A.2    Numoto, K.3    Kunisada, T.4    Wai, D.5    Ohata, N.6
  • 21
    • 79957901656 scopus 로고    scopus 로고
    • Prognostic significance of p14ARF, p15INK4b and p16INK4a inactivation in malignant peripheral nerve sheath tumors
    • M. Endo, C. Kobayashi, N. Setsu, Y. Takahashi, K. Kohashi, and H. Yamamoto Prognostic significance of p14ARF, p15INK4b and p16INK4a inactivation in malignant peripheral nerve sheath tumors Clin Cancer Res 17 2011 3771 3782
    • (2011) Clin Cancer Res , vol.17 , pp. 3771-3782
    • Endo, M.1    Kobayashi, C.2    Setsu, N.3    Takahashi, Y.4    Kohashi, K.5    Yamamoto, H.6
  • 22
    • 84859555316 scopus 로고    scopus 로고
    • The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells
    • L. Kohli, N. Kaza, N.J. Lavalley, K.L. Turner, S. Byer, and S.L. Carroll The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells Neuro-oncology 14 2012 266 277
    • (2012) Neuro-oncology , vol.14 , pp. 266-277
    • Kohli, L.1    Kaza, N.2    Lavalley, N.J.3    Turner, K.L.4    Byer, S.5    Carroll, S.L.6
  • 24
    • 71849098457 scopus 로고    scopus 로고
    • Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells
    • Y. Sekido Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells Cancer Sci 101 2010 1 6
    • (2010) Cancer Sci , vol.101 , pp. 1-6
    • Sekido, Y.1
  • 25
    • 60549108776 scopus 로고    scopus 로고
    • EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy
    • N. Holtkamp, E. Malzer, J. Zietsch, A.F. Okuducu, J. Mucha, and C. Mawrin EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy Neuro-oncology 10 2008 946 957
    • (2008) Neuro-oncology , vol.10 , pp. 946-957
    • Holtkamp, N.1    Malzer, E.2    Zietsch, J.3    Okuducu, A.F.4    Mucha, J.5    Mawrin, C.6
  • 26
    • 0037101580 scopus 로고    scopus 로고
    • Losses in chromosomes 17, 19, and 22q in neurofibromatosis type 1 and sporadic neurofibromas: A comparative genomic hybridization analysis
    • T. Koga, H. Iwasaki, M. Ishiguro, A. Matsuzaki, and M. Kikuchi Losses in chromosomes 17, 19, and 22q in neurofibromatosis type 1 and sporadic neurofibromas: a comparative genomic hybridization analysis Cancer Genet Cytogenet 136 2002 113 120
    • (2002) Cancer Genet Cytogenet , vol.136 , pp. 113-120
    • Koga, T.1    Iwasaki, H.2    Ishiguro, M.3    Matsuzaki, A.4    Kikuchi, M.5
  • 27
    • 0034738802 scopus 로고    scopus 로고
    • Gains in chromosomes 7, 8q, 15q and 17q are characteristic changes in malignant but not in benign peripheral nerve sheath tumors from patients with Recklinghausen's disease
    • H. Schmidt, H. Taubert, A. Meye, P. Wurl, M. Bache, and F. Bartel Gains in chromosomes 7, 8q, 15q and 17q are characteristic changes in malignant but not in benign peripheral nerve sheath tumors from patients with Recklinghausen's disease Cancer Lett 155 2000 181 190
    • (2000) Cancer Lett , vol.155 , pp. 181-190
    • Schmidt, H.1    Taubert, H.2    Meye, A.3    Wurl, P.4    Bache, M.5    Bartel, F.6
  • 28
    • 0042326348 scopus 로고    scopus 로고
    • NF2 tumor suppressor gene: A comprehensive and efficient detection of somatic mutations by denaturing HPLC and microarray-CGH
    • I. Szijan, D. Rochefort, C. Bruder, E. Surace, G. Machiavelli, and V. Dalamon NF2 tumor suppressor gene: a comprehensive and efficient detection of somatic mutations by denaturing HPLC and microarray-CGH Neuromolecular Med 3 2003 41 52
    • (2003) Neuromolecular Med , vol.3 , pp. 41-52
    • Szijan, I.1    Rochefort, D.2    Bruder, C.3    Surace, E.4    Machiavelli, G.5    Dalamon, V.6
  • 30
    • 0033981059 scopus 로고    scopus 로고
    • Population-based analysis of sporadic and type 2 neurofibromatosis- associated meningiomas and schwannomas
    • J. Antinheimo, R. Sankila, O. Carpen, E. Pukkala, M. Sainio, and J. Jaaskelainen Population-based analysis of sporadic and type 2 neurofibromatosis-associated meningiomas and schwannomas Neurology 54 2000 71 76
    • (2000) Neurology , vol.54 , pp. 71-76
    • Antinheimo, J.1    Sankila, R.2    Carpen, O.3    Pukkala, E.4    Sainio, M.5    Jaaskelainen, J.6
  • 31
    • 0033760978 scopus 로고    scopus 로고
    • Genetic aberrations in sporadic and neurofibromatosis 2 (NF2)-associated schwannomas studied by comparative genomic hybridization (CGH)
    • discussion 104-5
    • J. Antinheimo, S.L. Sallinen, P. Sallinen, H. Haapasalo, H. Helin, and N. Horelli-Kuitunen Genetic aberrations in sporadic and neurofibromatosis 2 (NF2)-associated schwannomas studied by comparative genomic hybridization (CGH) Acta Neurochirurgica 142 2000 1099 1104 discussion 104-5
    • (2000) Acta Neurochirurgica , vol.142 , pp. 1099-1104
    • Antinheimo, J.1    Sallinen, S.L.2    Sallinen, P.3    Haapasalo, H.4    Helin, H.5    Horelli-Kuitunen, N.6
  • 32
    • 0344874062 scopus 로고    scopus 로고
    • Identification of recurrent regions of chromosome loss and gain in vestibular schwannomas using comparative genomic hybridisation
    • C. Warren, L.A. James, R.T. Ramsden, A. Wallace, M.E. Baser, and J.M. Varley Identification of recurrent regions of chromosome loss and gain in vestibular schwannomas using comparative genomic hybridisation J Med Genet 40 2003 802 806
    • (2003) J Med Genet , vol.40 , pp. 802-806
    • Warren, C.1    James, L.A.2    Ramsden, R.T.3    Wallace, A.4    Baser, M.E.5    Varley, J.M.6
  • 33
    • 20944451522 scopus 로고    scopus 로고
    • Comparative genomic hybridization and mutation analyses of sporadic schwannomas
    • T. Ikeda, S. Hashimoto, S. Fukushige, H. Ohmori, and A. Horii Comparative genomic hybridization and mutation analyses of sporadic schwannomas J Neurooncol 72 2005 225 230
    • (2005) J Neurooncol , vol.72 , pp. 225-230
    • Ikeda, T.1    Hashimoto, S.2    Fukushige, S.3    Ohmori, H.4    Horii, A.5
  • 34
    • 27644467508 scopus 로고    scopus 로고
    • High-resolution array-CGH profiling of germline and tumor-specific copy number alterations on chromosome 22 in patients affected with schwannomas
    • T. Diaz de Stahl, C.M. Hansson, C. de Bustos, K.K. Mantripragada, A. Piotrowski, and M. Benetkiewicz High-resolution array-CGH profiling of germline and tumor-specific copy number alterations on chromosome 22 in patients affected with schwannomas Hum Genet 118 2005 35 44
    • (2005) Hum Genet , vol.118 , pp. 35-44
    • Diaz De Stahl, T.1    Hansson, C.M.2    De Bustos, C.3    Mantripragada, K.K.4    Piotrowski, A.5    Benetkiewicz, M.6


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