Anti-inflammatory and antioxidant activities of ethanolic extract of aerial parts of Vernonia patula (Dryand.) Merr.

Asian Pacific Journal of Tropical Biomedicine

Volumn 3, Issue 10, 2013, Pages 798-805

  Hira, Arpona ^a   Dey, Shubhra Kanti ^a   Howlader, Md Sariful Islam ^b   Ahmed, Arif ^a   Hossain, Hemayet ^c   Jahan, Ismet Ara ^c  

^a KHULNA UNIVERSITY   (Bangladesh)

^b WORLD UNIVERSITY OF BANGLADESH   (Bangladesh)

^c BCSIR Laboratories Dhaka   (Bangladesh)

Author keywords

Acute toxicity; Anti inflammatory; DPPH free radical scavenging; Nitric oxide radical scavenging; Reducing power; Vernonia patula

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ALCOHOL; ANTIINFLAMMATORY AGENT; ASCORBIC ACID; CARRAGEENAN; EDETIC ACID; GALLIC ACID; HISTAMINE; INDOMETACIN; NITRIC OXIDE; PHENOL; PLANT EXTRACT; UNCLASSIFIED DRUG; VERNONIA PATULA EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DETERMINATION; DRUG DOSE COMPARISON; DRUG SAFETY; INFLAMMATION; IRON CHELATION; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; RAT; TOXICITY TESTING; VERNONIA; VERNONIA PATULA;

ACUTE TOXICITY; ANTI-INFLAMMATORY; DPPH FREE-RADICAL SCAVENGING; NITRIC OXIDE RADICAL SCAVENGING; REDUCING POWER; VERNONIA PATULA;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; ETHANOL; FREE RADICAL SCAVENGERS; HISTAMINE; IRON CHELATING AGENTS; MALE; NITRIC OXIDE; OXIDATION-REDUCTION; PHENOLS; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; RATS; VERNONIA;

EID: 84883823750     PISSN: 22211691     EISSN: None     Source Type: Journal    
DOI: 10.1016/S2221-1691(13)60158-6     Document Type: Article

References (37)

1. Herrera CL, Chanco GL, Sison FM. Chemical and pharmacological studies on Vernonia patula (Dry.) Merr. and Vernonia cinerea (Linn.) Less. 4th Asian Symposium on Medicinal Plants and Spices; 1980 Sep 15-19; Bangkok, Thailand; 1980, p. 249.
2. Liang QL, Min ZD [Studies on the constituents from the herb of Vernonia patula]. Zhongguo Zhong Yao Za Zhi 2003, 28(3):235-237. Chinese.
3. Lin YL, Wang WY Chemical constituents of Vernonia patula. Chin Pharm J 2002, 54(3):187-192.
4. Evans WC Trease and Evan's pharmacognosy 1989, 546-547. University Press, Cambridge. 3rd ed.
5. Badakhshan MP, Subramanion LJ, Lachimanan YL, Yeng C, Sreenivasan S Antioxidant activity of methanol extracts of different parts of Lantana camara. Asian Pac J Trop Biomed 2012, 2(12):960-965.
6. Jude EO, Anwanga EU, Samuel GF, Louis UA Anti-inflammatory and analgesic activities of Melanthera scandens. Asian Pac J Trop Biomed 2012, 2(2):144-148.
7. Perianayagam JB, Sharma SK, Pillai KK Anti-inflammatory activity of Trichodesma indicum leaves extract in experimental animals. J Ethnopharmacol 2006, 104:410-414.
8. Khadem A, Ayesha A, Nripendra NB Analgesic, anti-inflammatory and anti-diarrheal activities of ethanolic leaf extract of Typhonium trilobatum L. Asian Pac J Trop Biomed 2012, 2(9):722-726.
9. Francis MA, Andrew WV Antioxidant activity, nitric oxide scavenging activity and phenolic contents of Ocimum gratissimum leaf extract. J Med Plants Res 2010, 4(24):2479-2487.
10. Robu SV, aprotosoaie AC, Miron A, Cioanc O, stǎnescu U, Hǎncianu M In vitro antioxidant activity of ethanolic extracts from some Lavandula species cultivated in Romania. Farmacia 2012, 60(3):394-401.
11. Sikder MA, Rahman MA, Islam MR, Kaisar MA, Rahman MS, Rashid MA In vitro antioxidant, reducing power, free radical scavenging and membrane stabilizing activities of Spilanthes calva. Bangladesh Pharm J 2010, 13(1):63-67.
12. Ejebe DE, Siminialayi IM, Emudainowho JO, Ofesi U, Morka L Analgesic and anti-inflammatory activities of the ethanol extract of the leaves of Helianthus annus in Wistar rats. Asian Pac J Trop Med 2010, 3(5):341-347.
13. Seibert K, Zhang Y, Leahy K, Hauser S, Masferrer J, Perkins W, et al. Pharmacological and biochemical demonstration of the role of cyclooxygenase-2 in inflammation and pain. Proc Natl Acad Sci U S A 1994, 91:12013-12017.
14. Cuman RK, Bersani-Amadio CA, Fortes ZB Influence of type 2 diabetes on the inflammatory response in rat. Inflamm Res 2001, 50:460-465.
15. Vasudevan M, Gunman KK, Parle M Antinociceptive and antiinflammatory effects of Thespesia populnea bark extract. J Ethnopharmacol 2007, 109:264-270.
16. Sawadogo WR, Boly R, Lompo M, Some N, Lamien CE, Guissou IP, et al. Anti-inflammatory, analgesic and antipyretic activities of Dicliptera verticillata. Int J Pharmacol 2006, 2:435-438.
17. Shimoi K, Saka N, Kaji K, Nozawa R Metabolic fate of luteolin and its functional activity on focal site. Biofactors 2000, 12:181-186.
18. Pan MH, Lai CS, Ho CT Anti-inflammatory activity of natural dietary flavonoids. Food Funct 2010, 1:15-31.
19. Wu Y, Zhou C, Song L, Li X, Shi S, Mo J, et al. Effect of total phenolics from Laggera alata on acute and chronic inflammatory models. J Ethnopharmacol 2006, 108:243-250.
20. Michaluart P, Masferrer JL, Carothers AM, Subbaramaiah K, Zweifel BS, Koboldt C, et al. Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation. Cancer Res 1999, 59:2347-2352.
21. Frenkel K, Wei H, Bhimani R, Ye J, Zadunaisky JA, Huang MT, et al. Inhibition of tumor promoter mediated processes in mouse skin and bovine lens by caffeic acid phenethyl ester. Cancer Res 1993, 53:1255-1261.
22. Rao CV, Desai D, Simi B, Kulkarni N, Amin S, Reddy BS Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon. Cancer Res 1993, 53:4182-4188.
23. Márquez N, Sancho R, Macho A, Calzado MA, Fiebich BL, Muñoz E Caffeic acid phenethyl ester inhibits T-cell activation by targeting both nuclear factor of activated T-cells and NF-kappaB transcription factors. J Pharmacol Exp Ther 2004, 308:993-1001.
24. Dhara AK, Suba V, Sen T, Pal S, Chaudhuri AK Preliminary studies on the anti-inflammatory and analgesic activity of the methanol fraction of the root extract of Tragia involucrata Linn. J Ethnopharmacol 2000, 72:265-268.
25. Mondal SK, Chakroborty G, Gupta M, Mazumder UK Hepatoprotective activity of Diospyros malabarica bark in carbon tetrachloride intoxicated rats. Eur Bull Drug Res 2005, 13:25-30.
26. Marcocci L, Packer L, Droy-Lefaix MT, Sekaki A, Gardès-Albert M Antioxidant action of Ginkgo biloba extracts EGb 761. Methods Enzymol 1994, 234:462-475.
27. Meir S, Kanner J, Akiri B, Philosoph-Hadas S Determination and involvement of aqueous reducing compounds in oxidative systems of various senescing leaves. J Agric Food Chem 1995, 43:1813-1819.
28. Yamaguchi F, Ariga T, Yoshimara Y, Nakazawa H Antioxidant and antiglycation of carcinol from Garcina indica fruit rind. J Agric Food Chem 2000, 48:180-185.
29. Duh PD, Tu YY, Yen GC Antioxidant activty of water extract of Harng Jyur (Chrysanthemum morifolium Ramat). LWT-Food Sci Technol 1999, 32:269-277.
30. Hatano T, Edamatsu R, Hiramatsu M, Mori A, Fujita Y, Yasuhara T, et al. Effects of the interaction of tannins with co-existing substances. VI: Effects of tannins and related polyphenols on superoxide anion radical and on 1, 1-diphenyl-2-picrylhydrazyl radical. Chem Pharm Bull 1989, 37:2016-2021.
31. Tanaka M, Kuie CW, Nagashima Y, Taguchi T Application of antioxidative Maillard reaction products from histidine and glucose to sardine products. Bull Jpn Soc Sci Fish 1988, 54:1409-1414.
32. Ningappa MB, Dinesha R, Srinivas L Antioxidant and free radical scavenging activities of polyphenol-enriched curry leaf (Murraya koenigii L.) extract. Food Chem 2008, 106:720-728.
33. Ponou BK, Teponno RB, Ricciutelli M, Quassinti L, Bramucci M, Lupidi G, et al. Dimeric antioxidant and cytotoxic triterpenoid saponins from Terminalia ivorensis A. Chev. Phytochemistry 2010, 71(17-18):2108-2115.
34. Yokozawa T, Chen CP, Dong E, Tanaka T, Nonaka GI, Nishioka I Study on the inhibitory effect of tannins and flavonoids against the 1, 1-Diphenyl-2 picrylhydrazyl Radical. Biochem Pharmacol 1998, 56(2):213-222.
35. Gülçin I, Huyut Z, Elmastaş M, Aboul-Enein HY Radical scavenging and antioxidant activity of tannic acid. Arab J Chem 2010, 3:43-53.
36. Pérez-García F, Adzet T, Cañigueral S Activity of artichoke leaf extract on reactive oxygen species in human leukocytes. Free Radic Res 2000, 33(5):661-665.
37. Van Acker SA, Tromp MN, Haenen GR, van der Vijgh WJ, Bast A Flavonoids as scavengers of nitric oxide radical. Biochem Biophys Res Commun 1995, 214(3):755-759.