Tumor cell death induced by the inhibition of mitochondrial electron transport: The effect of 3-hydroxybakuchiol

Toxicology and Applied Pharmacology

Volumn 272, Issue 2, 2013, Pages 356-364

  Jaña, Fabián ^a   Faini, Francesca ^a   Lapier, Michel ^a   Pavani, Mario ^a   Kemmerling, Ulrike ^b   Morello, Antonio ^a   Maya, Juan Diego ^a   Jara, José ^a   Parra, Eduardo ^c   Ferreira, Jorge ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSIDAD DE TARAPACÁ   (Chile)

Author keywords

3 hydroxybakuchiol; Apoptosis; Electron transport chain; Mitochondria

Indexed keywords

3 HYDROXYBAKUCHIOL; ANTINEOPLASTIC AGENT; CASPASE 3; CATECHOL DERIVATIVE; DUROQUINOL; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; REACTIVE OXYGEN METABOLITE; SUCCINIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; CANCER INHIBITION; CELL CYCLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; LIPOPHILICITY; MEMBRANE POTENTIAL; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION SWELLING; MOUSE; NICK END LABELING; NONHUMAN; OXYGEN CONSUMPTION; PSORALEA; RESPIRATORY CHAIN; TUMOR CELL;

3-HYDROXYBAKUCHIOL; 3-OHBK; ANALYSIS OF VARIANCE; ANOVA; APOPTOSIS; CASPASE-3-LIKE ENZYME; CSA; CYCLOSPORINE A; DCFDA; DEVDASE; DICHLOROFLUORESCEIN DIACETATE; DIMETHYL SULFOXIDE; DMEM; DMSO; DQ; DULBECCO'S MODIFIED EAGLE MEDIUM; DUROQUINOL; EGTA; ELECTRON TRANSPORT CHAIN; ETC; ETHYLENE GLYCOL TETRAACETIC ACID; FACS; FITC; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENCE-ACTIVATED CELL SORTING; G+M; GLUCOSE-6-P; GLUCOSE-6-PHOSPHATE; GLUTAMATE PLUS MALATE; HEXOKINASE II; HKII; MITOCHONDRIA; MITOCHONDRIAL PERMEABILITY TRANSPORT PORE; MPTP; NADH; OXIDATIVE PHOSPHORYLATION; OXPHOS; PBS; PHOSPHATE BUFFERED SALINE; PI; PROPIDIUM IODIDE; REACTIVE OXYGEN SPECIES; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RELATIVE FLUORESCENCE UNITS; RFU; ROS; SD; SEM; STANDARD DEVIATION; STANDARD ERROR OF THE MEAN; TERMINAL DEOXYURIDINE TRIPHOSPHATE NICK END LABELING; TETRAMETHYLRHODAMINE METHYL ESTER; TMRM; TUNEL; VDAC; VOLTAGE-DEPENDENT ANION CHANNEL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CATECHOLS; CELL CULTURE TECHNIQUES; CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; MITOCHONDRIAL SWELLING; MOLECULAR STRUCTURE; NECROSIS; PHENOLS; REACTIVE OXYGEN SPECIES;

EID: 84883810441     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.06.005     Document Type: Article

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