-
1
-
-
0036794815
-
Dopamine and antipsychotic drug action revisited
-
Jones HM, Pilowsky LS. Dopamine and antipsychotic drug action revisited. Br J Psychiatry. 2002;181:271-275
-
(2002)
Br J Psychiatry
, vol.181
, pp. 271-275
-
-
Jones, H.M.1
Pilowsky, L.S.2
-
2
-
-
0027520871
-
Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients
-
Nordstrom AL, Farde L,Wiesel FA, et al. Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients. Biol Psychiatry. 1993;33:227-235
-
(1993)
Biol Psychiatry
, vol.33
, pp. 227-235
-
-
Nordstrom, A.L.1
Farde, L.2
Wiesel, F.A.3
-
3
-
-
0034025771
-
Relationship between dopamine D 2) occupancy clinical response and side effects a double-blind PET study of first-episode schizophrenia
-
Kapur S, Zipursky R, Jones C, et al. Relationship between dopamine D(2) occupancy, clinical response, and side effects: A double-blind PET study of first-episode schizophrenia. Am J Psychiatry. 2000;157: 514-520
-
(2000)
Am J Psychiatry
, vol.157
, pp. 514-520
-
-
Kapur, S.1
Zipursky, R.2
Jones, C.3
-
4
-
-
0026643193
-
Clozapine, single photon emission tomography, and the D2 dopamine receptor blockade hypothesis of schizophrenia
-
Pilowsky LS, Costa DC, Ell PJ, et al. Clozapine, single photon emission tomography, and the D2 dopamine receptor blockade hypothesis of schizophrenia. Lancet. 1992;340:199-202
-
(1992)
Lancet
, vol.340
, pp. 199-202
-
-
Pilowsky, L.S.1
Costa, D.C.2
Ell, P.J.3
-
5
-
-
0031953450
-
Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors
-
Seeman P, Tallerico T. Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors. Mol Psychiatry. 1998;3:123-134
-
(1998)
Mol Psychiatry
, vol.3
, pp. 123-134
-
-
Seeman, P.1
Tallerico, T.2
-
6
-
-
0035094264
-
Does fast dissociation from the dopamine d (2) receptor explain the action of atypical antipsychotics?: A new hypothesis
-
Kapur S, Seeman P. Does fast dissociation from the dopamine d(2) receptor explain the action of atypical antipsychotics?: A new hypothesis. Am J Psychiatry. 2001;158:360-369
-
(2001)
Am J Psychiatry
, vol.158
, pp. 360-369
-
-
Kapur, S.1
Seeman, P.2
-
7
-
-
0029026941
-
The D2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: A PET study
-
Kapur S, Remington G, Zipursky RB, et al. The D2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: A PET study. Life Sci. 1995;57:103-107
-
(1995)
Life Sci
, vol.57
, pp. 103-107
-
-
Kapur, S.1
Remington, G.2
Zipursky, R.B.3
-
8
-
-
0034130233
-
Subjective experience and striatal dopamine D 2) receptor occupancy in patients with schizophrenia stabilized by olanzapine or risperidone
-
de Haan L, Lavalaye J, Linszen D, et al. Subjective experience and striatal dopamine D(2) receptor occupancy in patients with schizophrenia stabilized by olanzapine or risperidone. Am J Psychiatry. 2000;157: 1019-1020
-
(2000)
Am J Psychiatry
, vol.157
, pp. 1019-1020
-
-
De Haan, L.1
Lavalaye, J.2
Linszen, D.3
-
9
-
-
34247533866
-
Adverse subjective experience with antipsychotics and its relationship to striatal and extrastriatal D2 receptors: A PET study in schizophrenia
-
Mizrahi R, Rusjan P, Agid O, et al. Adverse subjective experience with antipsychotics and its relationship to striatal and extrastriatal D2 receptors: A PET study in schizophrenia. Am J Psychiatry. 2007;164: 630-637
-
(2007)
Am J Psychiatry
, vol.164
, pp. 630-637
-
-
Mizrahi, R.1
Rusjan, P.2
Agid, O.3
-
10
-
-
80054901956
-
Emotional experience and estimates of D (2) receptor occupancy in psychotic patients treated with haloperidol, risperidone, or olanzapine: An experience sampling study
-
Lataster J, van Os J, de Haan L, et al. Emotional experience and estimates of D(2) receptor occupancy in psychotic patients treated with haloperidol, risperidone, or olanzapine: An experience sampling study. J Clin Psychiatry. 2011;72:1397-1404
-
(2011)
J Clin Psychiatry
, vol.72
, pp. 1397-1404
-
-
Lataster, J.1
Van Os, J.2
De Haan, L.3
-
11
-
-
79952651319
-
Antipsychotic Occupancy of dopamine receptors in schizophrenia
-
Nord M, Farde L. Antipsychotic Occupancy of dopamine receptors in schizophrenia. CNS Neurosci Ther. 2011;17:97-103
-
(2011)
CNS Neurosci Ther
, vol.17
, pp. 97-103
-
-
Nord, M.1
Farde, L.2
-
12
-
-
70449435368
-
AmisulprideVdose, plasma concentration, occupancy and response: Implications for therapeutic drug monitoring
-
Sparshatt A, Taylor D, Patel MX, et al. AmisulprideVdose, plasma concentration, occupancy and response: Implications for therapeutic drug monitoring. Acta Psychiatr Scand. 2009;120:416-428
-
(2009)
Acta Psychiatr Scand
, vol.120
, pp. 416-428
-
-
Sparshatt, A.1
Taylor, D.2
Patel, M.X.3
-
13
-
-
79955640309
-
Predicting dopamine d2 receptor occupancy from plasma levels of antipsychotic drugs: A systematic review and pooled analysis
-
Uchida H, Takeuchi H, Graff-Guerrero A, et al. Predicting dopamine d2 receptor occupancy from plasma levels of antipsychotic drugs: A systematic review and pooled analysis. J Clin Psychopharmacol. 2011;31:318-325
-
(2011)
J Clin Psychopharmacol
, vol.31
, pp. 318-325
-
-
Uchida, H.1
Takeuchi, H.2
Graff-Guerrero, A.3
-
14
-
-
79960616055
-
Dopamine D2 receptor occupancy and clinical effects: A systematic review and pooled analysis
-
Uchida H, Takeuchi H, Graff-Guerrero A, et al. Dopamine D2 receptor occupancy and clinical effects: A systematic review and pooled analysis. J Clin Psychopharmacol. 2011;31:497-502
-
(2011)
J Clin Psychopharmacol
, vol.31
, pp. 497-502
-
-
Uchida, H.1
Takeuchi, H.2
Graff-Guerrero, A.3
-
15
-
-
68149148941
-
Cortical dopamine D2/D3 receptors are a common site of action for antipsychotic drugsVan original patient data meta-Analysis of the SPECT and PET in vivo receptor imaging literature
-
Stone JM, Davis JM, Leucht S, et al. Cortical dopamine D2/D3 receptors are a common site of action for antipsychotic drugsVan original patient data meta-Analysis of the SPECT and PET in vivo receptor imaging literature. Schizophr Bull. 2009;35:789-797
-
(2009)
Schizophr Bull
, vol.35
, pp. 789-797
-
-
Stone, J.M.1
Davis, J.M.2
Leucht, S.3
-
16
-
-
79951996416
-
Dopamine d (2) occupancy as a biomarker for antipsychotics: Quantifying the relationship with efficacy and extrapyramidal symptoms
-
De Greef R, Maloney A, Olsson-Gisleskog P, et al. Dopamine d(2) occupancy as a biomarker for antipsychotics: Quantifying the relationship with efficacy and extrapyramidal symptoms. AAPS J. 2011;13:121-130
-
(2011)
AAPS J
, vol.13
, pp. 121-130
-
-
De Greef, R.1
Maloney, A.2
Olsson-Gisleskog, P.3
-
17
-
-
0028170808
-
Distribution of D1-And D2-dopamine receptors, and dopamine and its metabolites in the human brain
-
Hall H, Sedvall G, Magnusson O, et al. Distribution of D1-And D2-dopamine receptors, and dopamine and its metabolites in the human brain. Neuropsychopharmacology. 1994;11:245-256
-
(1994)
Neuropsychopharmacology
, vol.11
, pp. 245-256
-
-
Hall, H.1
Sedvall, G.2
Magnusson, O.3
-
18
-
-
35048900928
-
Neuroreceptor imaging studies in schizophrenia
-
Frankle WG. Neuroreceptor imaging studies in schizophrenia. Harv Rev Psychiatry. 2007;15:212-232
-
(2007)
Harv Rev Psychiatry
, vol.15
, pp. 212-232
-
-
Frankle, W.G.1
-
19
-
-
0012144684
-
Neurochemical and neuropharmacological imaging in schizophrenia
-
In: Davis KL, Charney DS, Coyle JT, et al, eds. Philadelphia, PA: Lippincott Williams & Wilkins
-
Weinberger DR, Laruelle M. Neurochemical and neuropharmacological imaging in schizophrenia. In: Davis KL, Charney DS, Coyle JT, et al, eds. NeuropharmacologyVthe Fifth Generation of Progress. Philadelphia, PA: Lippincott, Williams & Wilkins; 2001
-
(2001)
NeuropharmacologyVthe Fifth Generation of Progress
-
-
Weinberger, D.R.1
Laruelle, M.2
-
20
-
-
0031595586
-
5-HT2 and D2 receptor occupancy of olanzapine in schizophrenia: A PET investigation
-
Kapur S, Zipursky RB, Remington G, et al. 5-HT2 and D2 receptor occupancy of olanzapine in schizophrenia: A PET investigation. Am J Psychiatry. 1998;155:921-928
-
(1998)
Am J Psychiatry
, vol.155
, pp. 921-928
-
-
Kapur, S.1
Zipursky, R.B.2
Remington, G.3
-
21
-
-
49349105633
-
Pharmacokinetics and time-course of D 2) receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients
-
Catafau AM, Penengo MM, Nucci G, et al. Pharmacokinetics and time-course of D(2) receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients. J Psychopharmacol. 2008;22:882-894
-
(2008)
J Psychopharmacol
, pp. 22882-894
-
-
Catafau, A.M.1
Penengo, M.M.2
Nucci, G.3
-
22
-
-
79960978687
-
Calculating occupancy when one does not have baseline: A comparison of different options
-
Kim E, Howes OD, Yu KS, et al. Calculating occupancy when one does not have baseline: A comparison of different options. J Cereb Blood Flow Metab. 2011;31:1760-1767
-
(2011)
J Cereb Blood Flow Metab
, vol.31
, pp. 1760-1767
-
-
Kim, E.1
Howes, O.D.2
Yu, K.S.3
-
27
-
-
0000499774
-
Delta method
-
In: Armitage P, Colton T eds. New York, NY: John Wiley
-
Cox C. Delta method. In: Armitage P, Colton T eds. Encyclopedia of Biostatistics. New York, NY: John Wiley; 1998;1125-1127
-
(1998)
Encyclopedia of Biostatistics
, pp. 1125-1127
-
-
Cox, C.1
-
28
-
-
2642561823
-
Subjective experience and dopamine D2 receptor occupancy in patients treated with antipsychotics: Clinical implications
-
de Haan L, Lavalaye J, van Bruggen M, et al. Subjective experience and dopamine D2 receptor occupancy in patients treated with antipsychotics: Clinical implications. Can J Psychiatry. 2004;49: 290-296
-
(2004)
Can J Psychiatry
, vol.49
, pp. 290-296
-
-
De Haan, L.1
Lavalaye, J.2
Van Bruggen, M.3
-
29
-
-
30344473331
-
Striatal D2 receptor binding as a marker of prognosis and outcome in untreated first-episode psychosis
-
Corripio I, Perez V, Catafau AM, et al. Striatal D2 receptor binding as a marker of prognosis and outcome in untreated first-episode psychosis. Neuroimage. 2006;29:662-666
-
(2006)
Neuroimage
, vol.29
, pp. 662-666
-
-
Corripio, I.1
Perez, V.2
Catafau, A.M.3
-
31
-
-
1642372241
-
Dose response and dose equivalence of antipsychotics
-
Davis JM, Chen N. Dose response and dose equivalence of antipsychotics. J Clin Psychopharmacol. 2004;24:192-208
-
(2004)
J Clin Psychopharmacol
, vol.24
, pp. 192-208
-
-
Davis, J.M.1
Chen, N.2
-
32
-
-
73549110068
-
Antipsychotic dose equivalents and dose-years: A standardized method for comparing exposure to different drugs
-
Andreasen NC, Pressler M, Nopoulos P, et al. Antipsychotic dose equivalents and dose-years: A standardized method for comparing exposure to different drugs. Biol Psychiatry. 2010;67:255-262
-
(2010)
Biol Psychiatry
, vol.67
, pp. 255-262
-
-
Andreasen, N.C.1
Pressler, M.2
Nopoulos, P.3
-
33
-
-
0029946719
-
High levels of dopamine D2 receptor occupancy with low-dose haloperidol treatment: A PET study
-
Kapur S, Remington G, Jones C, et al. High levels of dopamine D2 receptor occupancy with low-dose haloperidol treatment: A PET study. Am J Psychiatry. 1996;153:948-950
-
(1996)
Am J Psychiatry
, vol.153
, pp. 948-950
-
-
Kapur, S.1
Remington, G.2
Jones, C.3
-
34
-
-
0030613524
-
The relationship between D2 receptor occupancy and plasma levels on low dose oral haloperidol: A PET study
-
Kapur S, Zipursky R, Roy P, et al. The relationship between D2 receptor occupancy and plasma levels on low dose oral haloperidol: A PET study. Psychopharmacology (Berl). 1997;131:148-152
-
(1997)
Psychopharmacology (Berl
, vol.131
, pp. 148-152
-
-
Kapur, S.1
Zipursky, R.2
Roy, P.3
-
35
-
-
0034091239
-
A positron emission tomography study of quetiapine in schizophrenia: A preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy
-
Kapur S, Zipursky R, Jones C, et al. A positron emission tomography study of quetiapine in schizophrenia: A preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy. Arch Gen Psychiatry. 2000;57:553-559
-
(2000)
Arch Gen Psychiatry
, vol.57
, pp. 553-559
-
-
Kapur, S.1
Zipursky, R.2
Jones, C.3
-
36
-
-
0028176855
-
D2 dopamine receptor binding in the basal ganglia of antipsychotic-free schizophrenic patients. An 123I-IBZM single photon emission computerised tomography study
-
Pilowsky LS, Costa DC, Ell PJ, et al. D2 dopamine receptor binding in the basal ganglia of antipsychotic-free schizophrenic patients. An 123I-IBZM single photon emission computerised tomography study. Br J Psychiatry. 1994;164:16-26
-
(1994)
Br J Psychiatry
, vol.164
, pp. 16-26
-
-
Pilowsky, L.S.1
Costa, D.C.2
Ell, P.J.3
-
37
-
-
64049109285
-
Within-subject comparison of striatal d2 receptor occupancy measurements using [123i]ibzm spect and [11c]raclopride pet
-
Catafau AM, Suarez M, Bullich S, et al. Within-subject comparison of striatal D2 receptor occupancy measurements using [123I]IBZM SPECT and [11C]Raclopride PET. Neuroimage. 2009;46:447-458
-
(2009)
Neuroimage
, vol.46
, pp. 447-458
-
-
Catafau, A.M.1
Suarez, M.2
Bullich, S.3
-
38
-
-
0041349310
-
Analysis of D2 dopamine receptor occupancy with quantitative SPET using the high-Affinity ligand [123I]epidepride: Resolving conflicting findings
-
Erlandsson K, Bressan RA, Mulligan RS, et al. Analysis of D2 dopamine receptor occupancy with quantitative SPET using the high-Affinity ligand [123I]epidepride: Resolving conflicting findings. Neuroimage. 2003;19:1205-1214
-
(2003)
Neuroimage
, vol.19
, pp. 1205-1214
-
-
Erlandsson, K.1
Bressan, R.A.2
Mulligan, R.S.3
-
39
-
-
0034805368
-
Potentials and pitfalls using high affinity radioligands in PET and SPET determinations on regional drug induced D2 receptor occupancyVa simulation study based on experimental data
-
Olsson H, Farde L. Potentials and pitfalls using high affinity radioligands in PET and SPET determinations on regional drug induced D2 receptor occupancyVa simulation study based on experimental data. Neuroimage. 2001;14:936-945
-
(2001)
Neuroimage
, vol.14
, pp. 936-945
-
-
Olsson, H.1
Farde, L.2
-
40
-
-
0030300171
-
The D2 receptor occupancy profile of loxapine determined using PET
-
Kapur S, Zipursky RB, Jones C, et al. The D2 receptor occupancy profile of loxapine determined using PET. Neuropsychopharmacology. 1996;15:562-566
-
(1996)
Neuropsychopharmacology
, vol.15
, pp. 562-566
-
-
Kapur, S.1
Zipursky, R.B.2
Jones, C.3
-
41
-
-
1942475421
-
Estimation of the time-course of dopamine D2 receptor occupancy in living human brain from plasma pharmacokinetics of antipsychotics
-
Takano A, Suhara T, Ikoma Y, et al. Estimation of the time-course of dopamine D2 receptor occupancy in living human brain from plasma pharmacokinetics of antipsychotics. Int J Neuropsychopharmacol. 2004;7:19-26
-
(2004)
Int J Neuropsychopharmacol
, vol.7
, pp. 19-26
-
-
Takano, A.1
Suhara, T.2
Ikoma, Y.3
-
42
-
-
20144388474
-
Increased caudate dopamine D2 receptor availability as a genetic marker for schizophrenia
-
Hirvonen J, van Erp TG, Huttunen J, et al. Increased caudate dopamine D2 receptor availability as a genetic marker for schizophrenia. Arch Gen Psychiatry. 2005;62:371-378
-
(2005)
Arch Gen Psychiatry
, vol.62
, pp. 371-378
-
-
Hirvonen, J.1
Van Erp, T.G.2
Huttunen, J.3
-
44
-
-
50349096587
-
In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems
-
Meltzer HY, Huang M. In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems. Prog Brain Res. 2008;172:177-197
-
(2008)
Prog Brain Res
, vol.172
, pp. 177-197
-
-
Meltzer, H.Y.1
Huang, M.2
|