Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen-1 and nidogen-2

International Journal of Cancer

Volumn 133, Issue 10, 2013, Pages 2315-2324

  Martino Echarri, Estefanía ^a   Fernández Rodríguez, Rubén ^a   Rodríguez Baena, Francisco Javier ^a   Barrientos Durán, Antonio ^a   Torres Collado, Antoni X ^a   Del Carmen Plaza Calonge, María ^a   Amador Cubero, Suyapa ^a   Cortés, Javier ^b   Reynolds, Louise E ^c   Hodivala Dilke, Kairbaan M ^c   Rodríguez Manzaneque, Juan Carlos ^a  

^a JUNTA DE ANDALUCÍA   (Spain)

^b VALL D HEBRON UNIVERSITY HOSPITAL   (Spain)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

ADAMTS; breast carcinoma; extracellular proteolysis; nidogens; vascular basement membrane

Indexed keywords

ENTACTIN; NIDOGEN 1; NIDOGEN 2; PROTEINASE; UNCLASSIFIED DRUG;

ADAMTS1 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASEMENT MEMBRANE; BLOOD VESSEL; BREAST CARCINOMA; CANCER INHIBITION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE FUNCTION; HEMATOLOGICAL PARAMETERS; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; TISSUE SECTION; TISSUE STRUCTURE; TUMOR SUPPRESSOR GENE; TUMOR VASCULARIZATION; TUMOR XENOGRAFT;

ADAMTS; BREAST CARCINOMA; EXTRACELLULAR PROTEOLYSIS; NIDOGENS; VASCULAR BASEMENT MEMBRANE;

ADAM PROTEINS; ANIMALS; BASEMENT MEMBRANE; BREAST NEOPLASMS; CELL ADHESION MOLECULES; CELL LINE; DOWN-REGULATION; GENES, TUMOR SUPPRESSOR; GLYCOSAMINOGLYCANS; HEK293 CELLS; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDE HYDROLASES; PROTEOLYSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 84883805424     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28271     Document Type: Article

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