메뉴 건너뛰기




Volumn 167, Issue 6, 2013, Pages 2882-2888

Value of platelet pharmacogenetics in common clinical practice of patients with ST-segment elevation myocardial infarction

Author keywords

Antiplatelet therapy; Cyclooxygenase 1; Cytochrome P450 2C19; Pharmacogenetics; ST segment elevation myocardial infarction; Treatment outcome

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ALPHA2 INTEGRIN; ARYLDIALKYLPHOSPHATASE 1; CLOPIDOGREL; CYCLOOXYGENASE 1; CYTOCHROME P450 2C19; GLYCOPROTEIN IIIA; MULTIDRUG RESISTANCE PROTEIN 1; PURINERGIC P2Y1 RECEPTOR;

EID: 84883758234     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.07.020     Document Type: Article
Times cited : (30)

References (39)
  • 1
    • 84856164890 scopus 로고    scopus 로고
    • A systematic review on pharmacogenetics in cardiovascular disease: Is it ready for clinical application?
    • J.J. Verschuren, S. Trompet, and J.A. Wessels A systematic review on pharmacogenetics in cardiovascular disease: is it ready for clinical application? Eur Heart J 33 2 2012 165 175
    • (2012) Eur Heart J , vol.33 , Issue.2 , pp. 165-175
    • Verschuren, J.J.1    Trompet, S.2    Wessels, J.A.3
  • 2
    • 79960178505 scopus 로고    scopus 로고
    • Pharmacogenetics of antiplatelet therapy: Ready for clinical application?
    • J.J. Verschuren, and J.W. Jukema Pharmacogenetics of antiplatelet therapy: ready for clinical application? Heart 97 15 2011 1268 1276
    • (2011) Heart , vol.97 , Issue.15 , pp. 1268-1276
    • Verschuren, J.J.1    Jukema, J.W.2
  • 3
    • 78049326068 scopus 로고    scopus 로고
    • Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: A meta-analysis
    • J.L. Mega, T. Simon, and J.P. Collet Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis JAMA 304 16 2010 1821 1830
    • (2010) JAMA , vol.304 , Issue.16 , pp. 1821-1830
    • Mega, J.L.1    Simon, T.2    Collet, J.P.3
  • 4
    • 79957472412 scopus 로고    scopus 로고
    • Cytochrome P450 2C19(*)2 polymorphism and cardiovascular recurrences in patients taking clopidogrel: A meta-analysis
    • F. Sofi, B. Giusti, R. Marcucci, A.M. Gori, R. Abbate, and G.F. Gensini Cytochrome P450 2C19(*)2 polymorphism and cardiovascular recurrences in patients taking clopidogrel: a meta-analysis Pharmacogenomics J 11 3 2011 199 206
    • (2011) Pharmacogenomics J , vol.11 , Issue.3 , pp. 199-206
    • Sofi, F.1    Giusti, B.2    Marcucci, R.3    Gori, A.M.4    Abbate, R.5    Gensini, G.F.6
  • 5
    • 84155167902 scopus 로고    scopus 로고
    • Meta-analyses of the association between cytochrome CYP2C19 loss- and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel
    • M. Zabalza, I. Subirana, and J. Sala Meta-analyses of the association between cytochrome CYP2C19 loss- and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel Heart 98 2 2012 100 108
    • (2012) Heart , vol.98 , Issue.2 , pp. 100-108
    • Zabalza, M.1    Subirana, I.2    Sala, J.3
  • 6
    • 84858999257 scopus 로고    scopus 로고
    • Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: Systematic review and meta-analysis
    • T. Bauer, H.J. Bouman, J.W. van Werkum, N.F. Ford, J.M. ten Berg, and D. Taubert Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: systematic review and meta-analysis BMJ 343 2011 d4588
    • (2011) BMJ , vol.343 , pp. 4588
    • Bauer, T.1    Bouman, H.J.2    Van Werkum, J.W.3    Ford, N.F.4    Ten Berg, J.M.5    Taubert, D.6
  • 7
    • 84555195438 scopus 로고    scopus 로고
    • CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: A systematic review and meta-analysis
    • M.V. Holmes, P. Perel, T. Shah, A.D. Hingorani, and J.P. Casas CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis JAMA 306 24 2011 2704 2714
    • (2011) JAMA , vol.306 , Issue.24 , pp. 2704-2714
    • Holmes, M.V.1    Perel, P.2    Shah, T.3    Hingorani, A.D.4    Casas, J.P.5
  • 8
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • T. Simon, C. Verstuyft, and M. Mary-Krause Genetic determinants of response to clopidogrel and cardiovascular events N Engl J Med 360 4 2009 363 375
    • (2009) N Engl J Med , vol.360 , Issue.4 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 9
    • 77956353400 scopus 로고    scopus 로고
    • Protective effect of the CYP2C19*17 polymorphism with increased activation of clopidogrel on cardiovascular events
    • K.A. Tiroch, D. Sibbing, and W. Koch Protective effect of the CYP2C19*17 polymorphism with increased activation of clopidogrel on cardiovascular events Am Heart J 160 3 2010 506 512
    • (2010) Am Heart J , vol.160 , Issue.3 , pp. 506-512
    • Tiroch, K.A.1    Sibbing, D.2    Koch, W.3
  • 10
    • 43049179414 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 681G > A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents
    • D. Trenk, W. Hochholzer, and M.F. Fromm Cytochrome P450 2C19 681G > A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents J Am Coll Cardiol 51 20 2008 1925 1934
    • (2008) J Am Coll Cardiol , vol.51 , Issue.20 , pp. 1925-1934
    • Trenk, D.1    Hochholzer, W.2    Fromm, M.F.3
  • 11
    • 65249145201 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention
    • D. Sibbing, J. Stegherr, and W. Latz Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention Eur Heart J 30 8 2009 916 922
    • (2009) Eur Heart J , vol.30 , Issue.8 , pp. 916-922
    • Sibbing, D.1    Stegherr, J.2    Latz, W.3
  • 12
    • 33845316458 scopus 로고    scopus 로고
    • MISSION!: Optimization of acute and chronic care for patients with acute myocardial infarction
    • S.S. Liem, B.L. van der Hoeven, and P.V. Oemrawsingh MISSION!: optimization of acute and chronic care for patients with acute myocardial infarction Am Heart J 153 1 2007 14.e1 14.e11
    • (2007) Am Heart J , vol.153 , Issue.1
    • Liem, S.S.1    Van Der Hoeven, B.L.2    Oemrawsingh, P.V.3
  • 13
    • 34247558672 scopus 로고    scopus 로고
    • Clinical end points in coronary stent trials: A case for standardized definitions
    • D.E. Cutlip, S. Windecker, and R. Mehran Clinical end points in coronary stent trials: a case for standardized definitions Circulation 115 17 2007 2344 2351
    • (2007) Circulation , vol.115 , Issue.17 , pp. 2344-2351
    • Cutlip, D.E.1    Windecker, S.2    Mehran, R.3
  • 14
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • J.R. Vane Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs Nat New Biol 231 25 1971 232 235
    • (1971) Nat New Biol , vol.231 , Issue.25 , pp. 232-235
    • Vane, J.R.1
  • 15
    • 0037256309 scopus 로고    scopus 로고
    • Genetic variation in cyclooxygenase 1: Effects on response to aspirin
    • M.K. Halushka, L.P. Walker, and P.V. Halushka Genetic variation in cyclooxygenase 1: effects on response to aspirin Clin Pharmacol Ther 73 1 2003 122 130
    • (2003) Clin Pharmacol Ther , vol.73 , Issue.1 , pp. 122-130
    • Halushka, M.K.1    Walker, L.P.2    Halushka, P.V.3
  • 16
    • 33645546989 scopus 로고    scopus 로고
    • Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients
    • A. Lepantalo, J. Mikkelsson, and J.C. Resendiz Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients Thromb Haemost 95 2 2006 253 259
    • (2006) Thromb Haemost , vol.95 , Issue.2 , pp. 253-259
    • Lepantalo, A.1    Mikkelsson, J.2    Resendiz, J.C.3
  • 17
    • 28444484957 scopus 로고    scopus 로고
    • Cyclooxygenase-1 haplotype modulates platelet response to aspirin
    • A.O. Maree, R.J. Curtin, and A. Chubb Cyclooxygenase-1 haplotype modulates platelet response to aspirin J Thromb Haemost 3 10 2005 2340 2345
    • (2005) J Thromb Haemost , vol.3 , Issue.10 , pp. 2340-2345
    • Maree, A.O.1    Curtin, R.J.2    Chubb, A.3
  • 18
    • 60849137489 scopus 로고    scopus 로고
    • Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease
    • T.J. Kunicki, S.A. Williams, and D.J. Nugent Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease Thromb Haemost 101 1 2009 123 133
    • (2009) Thromb Haemost , vol.101 , Issue.1 , pp. 123-133
    • Kunicki, T.J.1    Williams, S.A.2    Nugent, D.J.3
  • 19
    • 64849112905 scopus 로고    scopus 로고
    • Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin
    • C. Pettinella, M. Romano, L. Stuppia, F. Santilli, R. Liani, and G. Davi Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin Thromb Haemost 101 4 2009 687 690
    • (2009) Thromb Haemost , vol.101 , Issue.4 , pp. 687-690
    • Pettinella, C.1    Romano, M.2    Stuppia, L.3    Santilli, F.4    Liani, R.5    Davi, G.6
  • 20
    • 46749115957 scopus 로고    scopus 로고
    • The C50T polymorphism of the cyclooxygenase-1 gene and the risk of thrombotic events during low-dose therapy with acetyl salicylic acid
    • N. Clappers, M.G. van Oijen, and S. Sundaresan The C50T polymorphism of the cyclooxygenase-1 gene and the risk of thrombotic events during low-dose therapy with acetyl salicylic acid Thromb Haemost 100 1 2008 70 75
    • (2008) Thromb Haemost , vol.100 , Issue.1 , pp. 70-75
    • Clappers, N.1    Van Oijen, M.G.2    Sundaresan, S.3
  • 21
    • 79960175185 scopus 로고    scopus 로고
    • Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use
    • D. Voora, J. Horton, S.H. Shah, L.K. Shaw, and L.K. Newby Polymorphisms associated with in vitro aspirin resistance are not associated with clinical outcomes in patients with coronary artery disease who report regular aspirin use Am Heart J 162 1 2011 166 172
    • (2011) Am Heart J , vol.162 , Issue.1 , pp. 166-172
    • Voora, D.1    Horton, J.2    Shah, S.H.3    Shaw, L.K.4    Newby, L.K.5
  • 22
    • 34547760330 scopus 로고    scopus 로고
    • A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease
    • M. Lordkipanidze, C. Pharand, E. Schampaert, J. Turgeon, D.A. Palisaitis, and J.G. Diodati A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease Eur Heart J 28 14 2007 1702 1708
    • (2007) Eur Heart J , vol.28 , Issue.14 , pp. 1702-1708
    • Lordkipanidze, M.1    Pharand, C.2    Schampaert, E.3    Turgeon, J.4    Palisaitis, D.A.5    Diodati, J.G.6
  • 23
    • 47249143688 scopus 로고    scopus 로고
    • Pharmacogenetics of aspirin resistance: A comprehensive systematic review
    • T. Goodman, A. Ferro, and P. Sharma Pharmacogenetics of aspirin resistance: a comprehensive systematic review Br J Clin Pharmacol 66 2 2008 222 232
    • (2008) Br J Clin Pharmacol , vol.66 , Issue.2 , pp. 222-232
    • Goodman, T.1    Ferro, A.2    Sharma, P.3
  • 25
    • 34250625249 scopus 로고    scopus 로고
    • Frequency of genetic polymorphisms of COX1, GPIIIa and P2Y1 in a Chinese population and association with attenuated response to aspirin
    • Q. Li, B.L. Chen, and V. Ozdemir Frequency of genetic polymorphisms of COX1, GPIIIa and P2Y1 in a Chinese population and association with attenuated response to aspirin Pharmacogenomics 8 6 2007 577 586
    • (2007) Pharmacogenomics , vol.8 , Issue.6 , pp. 577-586
    • Li, Q.1    Chen, B.L.2    Ozdemir, V.3
  • 26
    • 38849189504 scopus 로고    scopus 로고
    • Association of the platelet membrane glycoprotein i a C807T gene polymorphism with aspirin resistance
    • G. Su, Z. Wang, and Y. Ding Association of the platelet membrane glycoprotein I a C807T gene polymorphism with aspirin resistance J Huazhong Univ Sci Technol Med Sci 27 6 2007 664 667
    • (2007) J Huazhong Univ Sci Technol Med Sci , vol.27 , Issue.6 , pp. 664-667
    • Su, G.1    Wang, Z.2    Ding, Y.3
  • 27
    • 78651239845 scopus 로고    scopus 로고
    • Paraoxonase-1 is a major determinant of clopidogrel efficacy
    • H.J. Bouman, E. Schomig, and J.W. van Werkum Paraoxonase-1 is a major determinant of clopidogrel efficacy Nat Med 17 1 2011 110 116
    • (2011) Nat Med , vol.17 , Issue.1 , pp. 110-116
    • Bouman, H.J.1    Schomig, E.2    Van Werkum, J.W.3
  • 28
    • 79960012663 scopus 로고    scopus 로고
    • No association of paraoxonase-1 Q192R genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stenting
    • D. Sibbing, W. Koch, and S. Massberg No association of paraoxonase-1 Q192R genotypes with platelet response to clopidogrel and risk of stent thrombosis after coronary stenting Eur Heart J 32 13 2011 1605 1613
    • (2011) Eur Heart J , vol.32 , Issue.13 , pp. 1605-1613
    • Sibbing, D.1    Koch, W.2    Massberg, S.3
  • 29
    • 80052790906 scopus 로고    scopus 로고
    • Paraoxonase-1 Q192R polymorphism and antiplatelet effects of clopidogrel in patients undergoing elective coronary stent placement
    • D. Trenk, W. Hochholzer, and M.F. Fromm Paraoxonase-1 Q192R polymorphism and antiplatelet effects of clopidogrel in patients undergoing elective coronary stent placement Circ Cardiovasc Genet 4 4 2011 429 436
    • (2011) Circ Cardiovasc Genet , vol.4 , Issue.4 , pp. 429-436
    • Trenk, D.1    Hochholzer, W.2    Fromm, M.F.3
  • 31
    • 57549092687 scopus 로고    scopus 로고
    • The pharmacogenetics and pharmacodynamics of clopidogrel response: An analysis from the PRINC (Plavix Response in Coronary Intervention) trial
    • P. Gladding, M. Webster, and I. Zeng The pharmacogenetics and pharmacodynamics of clopidogrel response: an analysis from the PRINC (Plavix Response in Coronary Intervention) trial JACC Cardiovasc Interv 1 6 2008 620 627
    • (2008) JACC Cardiovasc Interv , vol.1 , Issue.6 , pp. 620-627
    • Gladding, P.1    Webster, M.2    Zeng, I.3
  • 32
    • 79952598836 scopus 로고    scopus 로고
    • Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: The GRAVITAS randomized trial
    • M.J. Price, P.B. Berger, and P.S. Teirstein Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: the GRAVITAS randomized trial JAMA 305 11 2011 1097 1105
    • (2011) JAMA , vol.305 , Issue.11 , pp. 1097-1105
    • Price, M.J.1    Berger, P.B.2    Teirstein, P.S.3
  • 33
    • 81855211733 scopus 로고    scopus 로고
    • Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease
    • J.L. Mega, W. Hochholzer, and A.L. Frelinger III Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease JAMA 306 20 2011 2221 2228
    • (2011) JAMA , vol.306 , Issue.20 , pp. 2221-2228
    • Mega, J.L.1    Hochholzer, W.2    Frelinger III, A.L.3
  • 34
    • 80053080512 scopus 로고    scopus 로고
    • High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI
    • G. Parodi, R. Marcucci, and R. Valenti High residual platelet reactivity after clopidogrel loading and long-term cardiovascular events among patients with acute coronary syndromes undergoing PCI JAMA 306 11 2011 1215 1223
    • (2011) JAMA , vol.306 , Issue.11 , pp. 1215-1223
    • Parodi, G.1    Marcucci, R.2    Valenti, R.3
  • 35
    • 66349133650 scopus 로고    scopus 로고
    • Cytochrome P450 genetic polymorphisms and the response to prasugrel: Relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes
    • J.L. Mega, S.L. Close, and S.D. Wiviott Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes Circulation 119 19 2009 2553 2560
    • (2009) Circulation , vol.119 , Issue.19 , pp. 2553-2560
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 36
    • 77958100874 scopus 로고    scopus 로고
    • Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: A genetic substudy of the PLATO trial
    • L. Wallentin, S. James, and R.F. Storey Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial Lancet 376 9749 2010 1320 1328
    • (2010) Lancet , vol.376 , Issue.9749 , pp. 1320-1328
    • Wallentin, L.1    James, S.2    Storey, R.F.3
  • 37
    • 77958128969 scopus 로고    scopus 로고
    • Guidelines on myocardial revascularization
    • W. Wijns, P. Kolh, and N. Danchin Guidelines on myocardial revascularization Eur Heart J 31 20 2010 2501 2555
    • (2010) Eur Heart J , vol.31 , Issue.20 , pp. 2501-2555
    • Wijns, W.1    Kolh, P.2    Danchin, N.3
  • 38
    • 79960613122 scopus 로고    scopus 로고
    • Clinical pharmacogenetics implementation consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy
    • S.A. Scott, K. Sangkuhl, and E.E. Gardner Clinical pharmacogenetics implementation consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy Clin Pharmacol Ther 90 2 2011 328 332
    • (2011) Clin Pharmacol Ther , vol.90 , Issue.2 , pp. 328-332
    • Scott, S.A.1    Sangkuhl, K.2    Gardner, E.E.3
  • 39
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • H. Schunkert, I.R. Konig, and S. Kathiresan Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease Nat Genet 43 4 2011 333 338
    • (2011) Nat Genet , vol.43 , Issue.4 , pp. 333-338
    • Schunkert, H.1    Konig, I.R.2    Kathiresan, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.